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Nasdaq · USD

IONS

IONIS PHARMACEUTICALS INC

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1182
SEC CIK
0000874015
Parsed reports
834

Last 12 months

Inside the activity.

2 purchase rows · 116 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025015
Dec 202502
Jan 2026029
Feb 202607
Mar 2026031
Apr 202609
May 202606
Jun 2026011
Jul 202626
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 01, 2017 Filed Mar 3, 2017 00:12 UTC
PARSHALL B LYNNEDirector · COO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 4,625 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-17-000023 · edgar.xml · derivative · entry 3

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,785

Underlying: Common Stock · 4,625 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:12 UTC
PARSHALL B LYNNEDirector · COO
SaleCommon Stock 4,625 $49.26 $227,827.50
Disclosure

SEC source: 0000874015-17-000023 · edgar.xml · nonDerivative · entry 2

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,651

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 7/13/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 7/13/2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.20 to $49.32, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:12 UTC
PARSHALL B LYNNEDirector · COO
Exercise / conversionCommon Stock 4,625 $14.69 $67,941.25
Disclosure

SEC source: 0000874015-17-000023 · edgar.xml · nonDerivative · entry 1

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,276

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 7/13/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 7/13/2016.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:11 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 500 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-17-000022 · edgar.xml · derivative · entry 4

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,926

Underlying: Common Stock · 500 shares

Expires 2020-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:11 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 1,000 $49.29 $49,290.00
Disclosure

SEC source: 0000874015-17-000022 · edgar.xml · nonDerivative · entry 3

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,449

F2 · kind: The sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F2 · shares: The sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.20 to $49.32, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:11 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 500 $49.29 $24,645.00
Disclosure

SEC source: 0000874015-17-000022 · edgar.xml · nonDerivative · entry 2

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,449

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
March 01, 2017 Filed Mar 3, 2017 00:11 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionCommon Stock 500 $10.82 $5,410.00
Disclosure

SEC source: 0000874015-17-000022 · edgar.xml · nonDerivative · entry 1

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,949

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 24, 2017 Filed Feb 28, 2017 00:15 UTC Exercise / conversionDirector Stock Option (right to buy) · Derivative 12,500 $0.00 Strike: $9.77 $0.00
Disclosure

SEC source: 0000874015-17-000020 · edgar.xml · derivative · entry 3

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 12,500 shares

Expires 2017-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 24, 2017 Filed Feb 28, 2017 00:15 UTC Exercise / conversionCommon Stock 12,500 $9.77 $122,125.00
Disclosure

SEC source: 0000874015-17-000020 · edgar.xml · nonDerivative · entry 1

BERTHELSEN SPENCER R · CIK 0001181548 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,958

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option that was scheduled to expire on 7/1/2017.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 7/1/2017.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 481 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · derivative · entry 7

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,426

Underlying: Common Stock · 481 shares

Expires 2020-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 19 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · derivative · entry 6

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,200

Underlying: Common Stock · 19 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 481 $46.50 $22,366.50
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · nonDerivative · entry 5

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,449

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionCommon Stock 481 $10.82 $5,204.42
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · nonDerivative · entry 4

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,930

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 19 $46.50 $883.50
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · nonDerivative · entry 3

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,449

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionCommon Stock 19 $7.25 $137.75
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · nonDerivative · entry 2

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,468

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 06, 2017 Filed Feb 8, 2017 23:32 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 1,000 $46.00 $46,004.00
Disclosure

SEC source: 0000874015-17-000019 · edgar.xml · nonDerivative · entry 1

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,449

F1 · kind: The sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

F1 · shares: The sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/6/2017.

Read SEC document
February 03, 2017 Filed Feb 3, 2017 23:31 UTC Exercise / conversionRestricted Stock Units · Derivative 937 $0.00 $0.00
Disclosure

SEC source: 0000874015-17-000018 · edgar.xml · derivative · entry 2

LOSCALZO JOSEPH · CIK 0001276128 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 937

Underlying: Common Stock · 937 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.

F3 · derivative.exercise_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

F3 · derivative.expiration_date: Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.

Read SEC document
February 03, 2017 Filed Feb 3, 2017 23:31 UTC Exercise / conversionCommon Stock 937 $0.00 $0.00
Disclosure

SEC source: 0000874015-17-000018 · edgar.xml · nonDerivative · entry 1

LOSCALZO JOSEPH · CIK 0001276128 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,814

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit award granted on February 3, 2014.

F1 · shares: Acquired pursuant to vesting and release of shares pursuant to a Restricted Stock Unit award granted on February 3, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:38 UTC
Monia Brett PSVP, Antisense Drug Discovery
SaleCommon Stock 623 $46.29 $28,838.67
Disclosure

SEC source: 0000874015-17-000016 · edgar.xml · nonDerivative · entry 8

Monia Brett P · CIK 0001537529 · SVP, Antisense Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,772

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:38 UTC
Monia Brett PSVP, Antisense Drug Discovery
SaleCommon Stock 593 $46.29 $27,450.56
Disclosure

SEC source: 0000874015-17-000016 · edgar.xml · nonDerivative · entry 6

Monia Brett P · CIK 0001537529 · SVP, Antisense Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,801

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:38 UTC
Monia Brett PSVP, Antisense Drug Discovery
SaleCommon Stock 733 $46.29 $33,931.30
Disclosure

SEC source: 0000874015-17-000016 · edgar.xml · nonDerivative · entry 4

Monia Brett P · CIK 0001537529 · SVP, Antisense Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,876

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:38 UTC
Monia Brett PSVP, Antisense Drug Discovery
SaleCommon Stock 553 $46.29 $25,598.37
Disclosure

SEC source: 0000874015-17-000016 · edgar.xml · nonDerivative · entry 2

Monia Brett P · CIK 0001537529 · SVP, Antisense Drug Discovery

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,734

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:48 UTC
Boyce SarahChief Business Officer
SaleCommon Stock 506 $46.29 $23,422.74
Disclosure

SEC source: 0000874015-17-000017 · edgar.xml · nonDerivative · entry 4

Boyce Sarah · CIK 0001629383 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,252

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:48 UTC
Boyce SarahChief Business Officer
SaleCommon Stock 855 $46.29 $39,577.95
Disclosure

SEC source: 0000874015-17-000017 · edgar.xml · nonDerivative · entry 2

Boyce Sarah · CIK 0001629383 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,463

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 623 $46.29 $28,838.67
Disclosure

SEC source: 0000874015-17-000015 · edgar.xml · nonDerivative · entry 10

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,449

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 512 $46.29 $23,700.99
Disclosure

SEC source: 0000874015-17-000015 · edgar.xml · nonDerivative · entry 8

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,478

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 733 $46.29 $33,930.57
Disclosure

SEC source: 0000874015-17-000015 · edgar.xml · nonDerivative · entry 6

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,679

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 256 $46.29 $11,850.24
Disclosure

SEC source: 0000874015-17-000015 · edgar.xml · nonDerivative · entry 4

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,537

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 122 $46.29 $5,647.75
Disclosure

SEC source: 0000874015-17-000015 · edgar.xml · nonDerivative · entry 2

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,140

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
BENNETT C FRANKSVP, Antisense Research
SaleCommon Stock 623 $46.29 $28,838.67
Disclosure

SEC source: 0000874015-17-000014 · edgar.xml · nonDerivative · entry 8

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,788

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
BENNETT C FRANKSVP, Antisense Research
SaleCommon Stock 512 $46.29 $23,700.99
Disclosure

SEC source: 0000874015-17-000014 · edgar.xml · nonDerivative · entry 6

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,817

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
BENNETT C FRANKSVP, Antisense Research
SaleCommon Stock 733 $46.29 $33,930.57
Disclosure

SEC source: 0000874015-17-000014 · edgar.xml · nonDerivative · entry 4

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,018

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:37 UTC
BENNETT C FRANKSVP, Antisense Research
SaleCommon Stock 553 $46.29 $25,598.37
Disclosure

SEC source: 0000874015-17-000014 · edgar.xml · nonDerivative · entry 2

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,876

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

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January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 131 $46.29 $6,063.99
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 16

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

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January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 142 $46.29 $6,573.32
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 14

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 2,859

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 139 $46.29 $6,434.31
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 12

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 2,638

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 163 $46.29 $7,545.43
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 2,423

F10 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

F10 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 4,410 $46.29 $204,138.90
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 3,728 $46.29 $172,569.12
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,291

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 4,236 $46.29 $196,080.20
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,144

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 3,008 $46.29 $139,237.31
Disclosure

SEC source: 0000874015-17-000013 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,568

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:35 UTC
Geary Richard SSVP, Development
SaleCommon Stock 623 $46.29 $28,839.29
Disclosure

SEC source: 0000874015-17-000010 · edgar.xml · nonDerivative · entry 8

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,962

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:35 UTC
Geary Richard SSVP, Development
SaleCommon Stock 539 $46.29 $24,950.31
Disclosure

SEC source: 0000874015-17-000010 · edgar.xml · nonDerivative · entry 6

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,991

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:35 UTC
Geary Richard SSVP, Development
SaleCommon Stock 733 $46.29 $33,931.30
Disclosure

SEC source: 0000874015-17-000010 · edgar.xml · nonDerivative · entry 4

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,150

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:35 UTC
Geary Richard SSVP, Development
SaleCommon Stock 546 $46.29 $25,274.89
Disclosure

SEC source: 0000874015-17-000010 · edgar.xml · nonDerivative · entry 2

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,008

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
PARSHALL B LYNNEDirector · COO
SaleCommon Stock 2,076 $46.29 $96,096.59
Disclosure

SEC source: 0000874015-17-000012 · edgar.xml · nonDerivative · entry 8

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,651

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
PARSHALL B LYNNEDirector · COO
SaleCommon Stock 2,696 $46.29 $124,796.49
Disclosure

SEC source: 0000874015-17-000012 · edgar.xml · nonDerivative · entry 6

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,245

F6 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

F6 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2015.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
PARSHALL B LYNNEDirector · COO
SaleCommon Stock 1,509 $46.29 $69,850.86
Disclosure

SEC source: 0000874015-17-000012 · edgar.xml · nonDerivative · entry 4

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,422

F4 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

F4 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2014.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:36 UTC
PARSHALL B LYNNEDirector · COO
SaleCommon Stock 965 $46.29 $44,670.04
Disclosure

SEC source: 0000874015-17-000012 · edgar.xml · nonDerivative · entry 2

PARSHALL B LYNNE · CIK 0001073385 · Director · COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,494

F2 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

F2 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 30, 2013.

Read SEC document
January 17, 2017 Filed Jan 18, 2017 23:35 UTC
HOUGEN ELIZABETH LSVP, Finance & CFO
SaleCommon Stock 623 $46.29 $28,838.67
Disclosure

SEC source: 0000874015-17-000011 · edgar.xml · nonDerivative · entry 10

HOUGEN ELIZABETH L · CIK 0001074773 · SVP, Finance & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,288

F8 · kind: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

F8 · shares: The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice, dated January 15, 2016.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.