Tapewire

Nasdaq · USD

IONS

IONIS PHARMACEUTICALS INC

Export transactions ↓
Tapewire entity
1182
SEC CIK
0000874015
Parsed reports
834

Last 12 months

Inside the activity.

2 purchase rows · 116 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025015
Dec 202502
Jan 2026029
Feb 202607
Mar 2026031
Apr 202609
May 202606
Jun 2026011
Jul 202626
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
October 13, 2017 Filed Oct 17, 2017 21:36 UTC
Geary Richard SSVP, Development
SaleCommon Stock 7,035 $60.00 $422,100.00
Disclosure

SEC source: 0000874015-17-000061 · edgar.xml · nonDerivative · entry 5

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,351

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

Read SEC document
October 13, 2017 Filed Oct 17, 2017 21:36 UTC
Geary Richard SSVP, Development
Exercise / conversionCommon Stock 7,035 $7.25 $51,003.75
Disclosure

SEC source: 0000874015-17-000061 · edgar.xml · nonDerivative · entry 4

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,386

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

Read SEC document
October 13, 2017 Filed Oct 17, 2017 21:36 UTC
Geary Richard SSVP, Development
SaleCommon Stock 426 $60.00 $25,560.00
Disclosure

SEC source: 0000874015-17-000061 · edgar.xml · nonDerivative · entry 3

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,351

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

Read SEC document
October 13, 2017 Filed Oct 17, 2017 21:36 UTC
Geary Richard SSVP, Development
Exercise / conversionCommon Stock 426 $10.29 $4,383.54
Disclosure

SEC source: 0000874015-17-000061 · edgar.xml · nonDerivative · entry 2

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,777

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 12/2/2016.

Read SEC document
October 13, 2017 Filed Oct 17, 2017 21:36 UTC
Geary Richard SSVP, Development
SaleCommon Stock 807 $60.00 $48,420.00
Disclosure

SEC source: 0000874015-17-000061 · edgar.xml · nonDerivative · entry 1

Geary Richard S · CIK 0001442730 · SVP, Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,351

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 12/2/2016.

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 12/2/2016.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 800 $0.00 Strike: $10.82 $0.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · derivative · entry 6

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,700

Underlying: Common Stock · 800 shares

Expires 2020-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 200 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · derivative · entry 5

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 200 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 800 $55.00 $44,000.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · nonDerivative · entry 4

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,433

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionCommon Stock 800 $10.82 $8,656.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · nonDerivative · entry 3

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
SaleCommon Stock 200 $55.00 $11,000.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · nonDerivative · entry 2

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,433

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
October 05, 2017 Filed Oct 6, 2017 20:41 UTC
O'NEIL PATRICK R.SVP, Legal & General Counsel
Exercise / conversionCommon Stock 200 $7.25 $1,450.00
Disclosure

SEC source: 0000874015-17-000060 · edgar.xml · nonDerivative · entry 1

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,633

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,000 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · derivative · entry 25

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 2,404

Underlying: Common Stock · 1,000 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · derivative · entry 24

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,642

Underlying: Common Stock · 10,000 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 500 $54.25 $27,125.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 20

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 500 $7.25 $3,625.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 19

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 500 $54.20 $27,100.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 18

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 500 $7.25 $3,625.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 17

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 5,000 $54.25 $271,250.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 16

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 5,000 $14.69 $73,450.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 15

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 5,000 $54.20 $271,000.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 14

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 04, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 5,000 $14.69 $73,450.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 13

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,500 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · derivative · entry 23

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,404

Underlying: Common Stock · 1,500 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 15,000 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · derivative · entry 22

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 91,642

Underlying: Common Stock · 15,000 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 500 $52.50 $26,250.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 12

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 500 $7.25 $3,625.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 11

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 500 $52.05 $26,025.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 10

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 500 $7.25 $3,625.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 9

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 500 $51.45 $25,725.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 8

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 500 $7.25 $3,625.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,562

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F2 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 5,000 $52.50 $262,500.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 5,000 $14.69 $73,450.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 5

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 5,000 $52.05 $260,250.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 5,000 $14.69 $73,450.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 5,000 $51.45 $257,250.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
October 02, 2017 Filed Oct 4, 2017 23:15 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 5,000 $14.69 $73,450.00
Disclosure

SEC source: 0000874015-17-000058 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document
September 06, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 800 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · derivative · entry 6

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200

Underlying: CommonStock · 800 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 06, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
SaleCommon Stock 800 $55.00 $44,000.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · nonDerivative · entry 4

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,433

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
September 06, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
Exercise / conversionCommon Stock 800 $7.25 $5,800.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · nonDerivative · entry 3

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
September 05, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 200 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · derivative · entry 5

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

Underlying: CommonStock · 200 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 05, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
SaleCommon Stock 200 $55.00 $11,000.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · nonDerivative · entry 2

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,433

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
September 05, 2017 Filed Sep 8, 2017 00:23 UTC
O'NEIL PATRICK R.SVP, Legal and General Counsel
Exercise / conversionCommon Stock 200 $7.25 $1,450.00
Disclosure

SEC source: 0001140361-17-034864 · form4.xml · nonDerivative · entry 1

O'NEIL PATRICK R. · CIK 0001564926 · SVP, Legal and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,633

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/30/2017.

Read SEC document
July 24, 2017 Filed Jul 27, 2017 00:03 UTC
BENNETT C FRANKSVP, Antisense Research
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $10.29 $0.00
Disclosure

SEC source: 0000874015-17-000052 · edgar.xml · derivative · entry 3

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,250

Underlying: Common Stock · 10,000 shares

Expires 2018-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 24, 2017 Filed Jul 27, 2017 00:03 UTC
BENNETT C FRANKSVP, Antisense Research
SaleCommon Stock 10,000 $59.29 $592,900.00
Disclosure

SEC source: 0000874015-17-000052 · edgar.xml · nonDerivative · entry 2

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,041

F1 · kind: Acquired as a result of exercising a stock option that was scheduled to expire on 1/2/2018. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/27/2015.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/2/2018. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/27/2015.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.25 to $59.33, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Read SEC document
July 24, 2017 Filed Jul 27, 2017 00:03 UTC
BENNETT C FRANKSVP, Antisense Research
Exercise / conversionCommon Stock 10,000 $10.29 $102,900.00
Disclosure

SEC source: 0000874015-17-000052 · edgar.xml · nonDerivative · entry 1

BENNETT C FRANK · CIK 0001073387 · SVP, Antisense Research

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option that was scheduled to expire on 1/2/2018. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/27/2015.

F1 · shares: Acquired as a result of exercising a stock option that was scheduled to expire on 1/2/2018. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 1/27/2015.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option · Derivative 1,000 $0.00 Strike: $7.25 $0.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · derivative · entry 7

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 4,904

Underlying: Common Stock · 1,000 shares

Expires 2019-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $14.69 $0.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · derivative · entry 6

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,642

Underlying: Common Stock · 10,000 shares

Expires 2020-01-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 1,000 $55.35 $55,350.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · nonDerivative · entry 4

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 3,062

F3 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F3 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $55.20 to $55.50, inclusive. The reporting person's wife undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) on this Form 4.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 1,000 $7.25 $7,250.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · nonDerivative · entry 3

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By wife

Disclosed balance after: 4,062

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

F3 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person's wife on 6/17/2016.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
SaleCommon Stock 10,000 $55.35 $553,500.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · nonDerivative · entry 2

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,014

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $55.20 to $55.50, inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc., any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Read SEC document
July 20, 2017 Filed Jul 24, 2017 21:54 UTC
CROOKE STANLEY TDirector · Chairman and CEO
Exercise / conversionCommon Stock 10,000 $14.69 $146,900.00
Disclosure

SEC source: 0000874015-17-000051 · edgar.xml · nonDerivative · entry 1

CROOKE STANLEY T · CIK 0000897667 · Director · Chairman and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,014

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

F1 · shares: Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 6/17/2016.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.