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Nasdaq · USD

INCY

INCYTE CORP

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3182
SEC CIK
0000879169
Parsed reports
950

Last 12 months

Inside the activity.

0 purchase rows · 46 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202507
Dec 202509
Jan 202602
Feb 202601
Mar 202601
Apr 202601
May 202602
Jun 202601
Jul 2026015
Aug 202605
Sep 202602
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 11, 2019 Filed Feb 13, 2019 21:20 UTC
Stamoulis ChristianaEVP & Chief Financial Officer
GrantEmployee Stock Option (right to buy) · Derivative 72,809 $0.00 Strike: $80.21 $0.00
Disclosure

SEC source: 0001209191-19-009612 · doc4.xml · derivative · entry 2

Stamoulis Christiana · CIK 0001502917 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,809

Underlying: Common Stock · 72,809 shares

Expires 2029-02-11

F2 · derivative.exercise_date: Beginning February 11, 2019, options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years.

Read SEC document
February 11, 2019 Filed Feb 13, 2019 21:20 UTC
Stamoulis ChristianaEVP & Chief Financial Officer
GrantCommon Stock 10,285 $80.21 $824,959.85
Disclosure

SEC source: 0001209191-19-009612 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,285

F1 · shares: Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years, subject to Ms. Christiana Stamoulis's continued service with the issuer through the applicable vesting dates. The RSUs may be settled only for shares of common stock on a one-for-one basis.

Read SEC document
February 01, 2019 Filed Feb 5, 2019 21:36 UTC
SWAIN PAULA JEVP, Human Resources
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $18.32 $0.00
Disclosure

SEC source: 0001209191-19-007362 · doc4.xml · derivative · entry 3

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,782

Underlying: Common Stock · 10,000 shares

Expires 2020-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Beginning February 9, 2013, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years.

Read SEC document
February 01, 2019 Filed Feb 5, 2019 21:36 UTC
SWAIN PAULA JEVP, Human Resources
SaleCommon Stock 10,000 $81.19 $811,900.00
Disclosure

SEC source: 0001209191-19-007362 · doc4.xml · nonDerivative · entry 2

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,124

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

F2 · price: Reporting person undertakes to provide upon request by Securites and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within range indicated.

F3 · price: Represents weighted average sale price. Actual sale prices ranged from $80.69 - $81.59.

F4 · balance_after: This includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
February 01, 2019 Filed Feb 5, 2019 21:36 UTC
SWAIN PAULA JEVP, Human Resources
Exercise / conversionCommon Stock 10,000 $18.32 $183,200.00
Disclosure

SEC source: 0001209191-19-007362 · doc4.xml · nonDerivative · entry 1

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,124

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 28, 2019 Filed Jan 30, 2019 21:22 UTC
Flannelly Barry PEVP & General Manager US
SaleCommon Stock 1,000 $80.00 $80,000.00
Disclosure

SEC source: 0001209191-19-006004 · doc4.xml · nonDerivative · entry 1

Flannelly Barry P · CIK 0001615842 · EVP & General Manager US

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,944

F1 · shares: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

F2 · balance_after: Includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 17, 2019 Filed Jan 22, 2019 23:04 UTC
Wenqing YaoEVP, Head of Discovery Chem
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 15,354 $0.00 Strike: $17.79 $0.00
Disclosure

SEC source: 0001209191-19-004819 · doc4.xml · derivative · entry 3

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,354 shares

Expires 2019-01-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Beginning January 19, 2012, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years.

Read SEC document
January 17, 2019 Filed Jan 22, 2019 23:04 UTC
Wenqing YaoEVP, Head of Discovery Chem
SaleCommon Stock 15,354 $77.61 $1,191,623.94
Disclosure

SEC source: 0001209191-19-004819 · doc4.xml · nonDerivative · entry 2

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,409

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

F2 · price: Represents weighted average sale price. Actual sale prices ranged from $76.43 to $78.56.

F3 · price: Reporting person undertakes to provide upon request by Securites and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within range indicated.

F4 · balance_after: This includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 17, 2019 Filed Jan 22, 2019 23:04 UTC
Wenqing YaoEVP, Head of Discovery Chem
Exercise / conversionCommon Stock 15,354 $17.79 $273,147.66
Disclosure

SEC source: 0001209191-19-004819 · doc4.xml · nonDerivative · entry 1

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,763

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 15, 2019 Filed Jan 17, 2019 21:15 UTC
Trower PaulPrincipal Accounting Officer
Exercise / conversionIncentive Stock Option (right to buy) · Derivative 5,813 $0.00 Strike: $17.79 $0.00
Disclosure

SEC source: 0001209191-19-004192 · doc4.xml · derivative · entry 3

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,813 shares

Expires 2019-01-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Beginning January 19, 2012, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years

Read SEC document
January 15, 2019 Filed Jan 17, 2019 21:15 UTC
Trower PaulPrincipal Accounting Officer
SaleCommon Stock 5,813 $75.00 $435,975.00
Disclosure

SEC source: 0001209191-19-004192 · doc4.xml · nonDerivative · entry 2

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,900

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

F2 · balance_after: This includes an 4,797 aggregate of shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 15, 2019 Filed Jan 17, 2019 21:15 UTC
Trower PaulPrincipal Accounting Officer
Exercise / conversionCommon Stock 5,813 $17.79 $103,413.27
Disclosure

SEC source: 0001209191-19-004192 · doc4.xml · nonDerivative · entry 1

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,713

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 08, 2019 Filed Jan 10, 2019 21:11 UTC
Flannelly Barry PEVP & General Manager US
SaleCommon Stock 1,714 $75.56 $129,509.84
Disclosure

SEC source: 0001209191-19-003251 · doc4.xml · nonDerivative · entry 1

Flannelly Barry P · CIK 0001615842 · EVP & General Manager US

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,944

F1 · shares: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

F2 · balance_after: Includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:46 UTC
Wenqing YaoEVP, Head of Discovery Chem
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 10,000 $0.00 Strike: $17.79 $0.00
Disclosure

SEC source: 0001209191-19-002811 · doc4.xml · derivative · entry 5

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,354

Underlying: Common Stock · 10,000 shares

Expires 2019-01-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Beginning January 19, 2012, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:46 UTC
Wenqing YaoEVP, Head of Discovery Chem
Tax withholdingCommon Stock 808 $74.21 $59,961.68
Disclosure

SEC source: 0001209191-19-002811 · doc4.xml · nonDerivative · entry 3

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,409

F2 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F3 · balance_after: This includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:46 UTC
Wenqing YaoEVP, Head of Discovery Chem
SaleCommon Stock 10,000 $75.00 $750,000.00
Disclosure

SEC source: 0001209191-19-002811 · doc4.xml · nonDerivative · entry 2

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,217

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:46 UTC
Wenqing YaoEVP, Head of Discovery Chem
Exercise / conversionCommon Stock 10,000 $17.79 $177,900.00
Disclosure

SEC source: 0001209191-19-002811 · doc4.xml · nonDerivative · entry 1

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,217

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
Tax withholdingCommon Stock 1,200 $74.21 $89,052.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · nonDerivative · entry 3

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,124

F2 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F3 · balance_after: This includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 9,187 $0.00 Strike: $17.79 $0.00
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · derivative · entry 6

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 9,187 shares

Expires 2019-01-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Beginning January 19, 2012, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
Tax withholdingCommon Stock 272 $74.21 $20,185.12
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · nonDerivative · entry 3

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,900

F2 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F3 · balance_after: This includes an aggregate of 4,797 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
SaleCommon Stock 9,187 $75.00 $689,025.00
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · nonDerivative · entry 2

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,172

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
Exercise / conversionCommon Stock 9,187 $17.79 $163,436.73
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · nonDerivative · entry 1

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,359

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:32 UTC
Stein Steven HEVP & Chief Medical Officer
Tax withholdingCommon Stock 847 $74.21 $62,855.87
Disclosure

SEC source: 0001209191-19-002792 · doc4.xml · nonDerivative · entry 1

Stein Steven H · CIK 0001673776 · EVP & Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,773

F1 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F2 · balance_after: Includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:16 UTC
Flannelly Barry PEVP & General Manager US
Tax withholdingCommon Stock 896 $74.21 $66,492.16
Disclosure

SEC source: 0001209191-19-002767 · doc4.xml · nonDerivative · entry 1

Flannelly Barry P · CIK 0001615842 · EVP & General Manager US

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,658

F1 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F2 · balance_after: Includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 07, 2019 Filed Jan 8, 2019 21:22 UTC
Hoppenot HerveDirector · Chairman / CEO · President
Tax withholdingCommon Stock 4,604 $74.21 $341,662.84
Disclosure

SEC source: 0001209191-19-002773 · doc4.xml · nonDerivative · entry 1

Hoppenot Herve · CIK 0001596492 · Director · Chairman / CEO · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,532

F1 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F2 · balance_after: Includes an aggregate of 87,728 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:46 UTC
Wenqing YaoEVP, Head of Discovery Chem
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002811 · doc4.xml · derivative · entry 4

Wenqing Yao · CIK 0001624033 · EVP, Head of Discovery Chem

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F4 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 30,000 $0.00 Strike: $18.32 $0.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · derivative · entry 6

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,782

Underlying: Common Stock · 30,000 shares

Expires 2020-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Beginning February 9, 2013, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
GrantEmployee Stock Option (right to buy) · Derivative 31,552 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · derivative · entry 5

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,552

Underlying: Common Stock · 31,552 shares

Expires 2029-01-03

F5 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in full on January 4, 2023.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · derivative · entry 4

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F4 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
SaleCommon Stock 30,000 $70.00 $2,100,000.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · nonDerivative · entry 2

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,324

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:37 UTC
SWAIN PAULA JEVP, Human Resources
Exercise / conversionCommon Stock 30,000 $18.32 $549,600.00
Disclosure

SEC source: 0001209191-19-002796 · doc4.xml · nonDerivative · entry 1

SWAIN PAULA J · CIK 0001236934 · EVP, Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,324

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
GrantEmployee Stock Option (right to buy) · Derivative 7,377 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · derivative · entry 5

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,377

Underlying: Common Stock · 7,377 shares

Expires 2029-01-03

F5 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in full on January 4, 2023.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:42 UTC
Trower PaulPrincipal Accounting Officer
GrantEmployee Stock Option (right to buy) · Derivative 6,298 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002803 · doc4.xml · derivative · entry 4

Trower Paul · CIK 0001642041 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,298

Underlying: Common Stock · 6,298 shares

Expires 2029-01-03

F4 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:32 UTC
Stein Steven HEVP & Chief Medical Officer
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002792 · doc4.xml · derivative · entry 2

Stein Steven H · CIK 0001673776 · EVP & Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F3 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:28 UTC
Pasquale Maria EEVP & General Counsel
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002790 · doc4.xml · derivative · entry 1

Pasquale Maria E · CIK 0001736295 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F1 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:25 UTC
Iyengar Vijay KEVP GPS, BD, & Licensing
GrantEmployee Stock Option (right to buy) · Derivative 31,552 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002783 · doc4.xml · derivative · entry 2

Iyengar Vijay K · CIK 0001670000 · EVP GPS, BD, & Licensing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,552

Underlying: Common Stock · 31,552 shares

Expires 2029-01-03

F2 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in full on January 4, 2023.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:25 UTC
Iyengar Vijay KEVP GPS, BD, & Licensing
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002783 · doc4.xml · derivative · entry 1

Iyengar Vijay K · CIK 0001670000 · EVP GPS, BD, & Licensing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F1 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

Read SEC document
January 04, 2019 Filed Jan 8, 2019 21:16 UTC
Flannelly Barry PEVP & General Manager US
GrantEmployee Stock Option (right to buy) · Derivative 63,105 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002767 · doc4.xml · derivative · entry 3

Flannelly Barry P · CIK 0001615842 · EVP & General Manager US

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,105

Underlying: Common Stock · 63,105 shares

Expires 2029-01-03

F4 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in full on January 4, 2023.

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January 04, 2019 Filed Jan 8, 2019 21:16 UTC
Flannelly Barry PEVP & General Manager US
GrantEmployee Stock Option (right to buy) · Derivative 22,772 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002767 · doc4.xml · derivative · entry 2

Flannelly Barry P · CIK 0001615842 · EVP & General Manager US

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,772

Underlying: Common Stock · 22,772 shares

Expires 2029-01-03

F3 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

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January 04, 2019 Filed Jan 8, 2019 21:22 UTC
Hoppenot HerveDirector · Chairman / CEO · President
GrantEmployee Stock Option (right to buy) · Derivative 88,558 $0.00 Strike: $72.27 $0.00
Disclosure

SEC source: 0001209191-19-002773 · doc4.xml · derivative · entry 3

Hoppenot Herve · CIK 0001596492 · Director · Chairman / CEO · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,558

Underlying: Common Stock · 88,558 shares

Expires 2029-01-03

F4 · derivative.exercise_date: Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years.

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January 02, 2019 Filed Jan 3, 2019 21:20 UTC
Hoppenot HerveDirector · Chairman / CEO · President
Tax withholdingCommon Stock 27,630 $63.56 $1,756,162.80
Disclosure

SEC source: 0001209191-19-000921 · doc4.xml · nonDerivative · entry 1

Hoppenot Herve · CIK 0001596492 · Director · Chairman / CEO · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 157,136

F1 · shares: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock.

F2 · balance_after: Includes an aggregate of 98,170 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested.

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December 31, 2018 Filed Jan 2, 2019 21:10 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
14159, L.P.Director · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
GrantCommon Stock 298 $63.59 $18,949.82
Disclosure

SEC source: 0001638599-19-000003 · doc4_5838.xml · nonDerivative · entry 6

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

14159, L.P. · CIK 0001551138 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 810,862

F4 · ownership.nature: 298 shares of common stock (the "Common Stock") issued to Julian C. Baker pursuant to the Issuer's Amended and Restated 2010 Stock Incentive Plan (the "Stock Incentive Plan") in lieu of director retainer fees of $19,000. The shares of Common Stock are fully vested. Julian C. Baker serves on the Issuer's Board of Directors (the "Board") as a representative of the Funds (as defined below).

F5 · ownership.nature: Pursuant to the policies of Baker Bros. Advisors LP (the "Adviser"), Julian C. Baker does not have any right to the pecuniary interest in the Issuer's securities issued in lieu of director retainer fees and the Funds (as defined below) are entitled to an indirect proportionate pecuniary interest in the securities. 667, L.P. ("667"), Baker Brothers Life Sciences, L.P. ("Life Sciences") and 14159, L.P. ("14159", and together with 667, and Life Sciences, the "Funds") each owns an indirect proportionate pecuniary interest in the shares of Common Stock. Solely as a result of their ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the shares of Common Stock issued in lieu of director retainer fees (ie. no direct pecuniary interest).

F8 · ownership.nature: As a result of Felix J. Baker's and Julian C. Baker's ownership interest in 14159 Capital (GP), LLC, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in 810,862 shares of common stock of the Issuer beneficially owned by 14159, a limited partnership of which the sole general partner is 14159 Capital, L.P., a limited partnership of which the sole general partner is 14159 Capital (GP), LLC, due to 14159 Capital, L.P.'s right to receive an allocation of a portion of the profits from 14159. Includes beneficial ownership of 3,156 shares issued pursuant to the Stock Incentive Plan in lieu of director retainer fees and 115,000 shares received previously from exercise of 115,000 stock options of the Issuer that were issued to Julian C. Baker in his capacity as a director of the Issuer, of which the fund may be deemed to own a portion.

F9 · ownership.nature: The Adviser serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are Managing Members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds.

F10 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F11 · ownership.nature: The 298 shares are reported for each of the Funds as each has an indirect pecuniary interest.

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December 31, 2018 Filed Jan 2, 2019 21:10 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
14159, L.P.Director · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
GrantCommon Stock 298 $63.59 $18,949.82
Disclosure

SEC source: 0001638599-19-000003 · doc4_5838.xml · nonDerivative · entry 5

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

14159, L.P. · CIK 0001551138 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 29,268,793

F4 · ownership.nature: 298 shares of common stock (the "Common Stock") issued to Julian C. Baker pursuant to the Issuer's Amended and Restated 2010 Stock Incentive Plan (the "Stock Incentive Plan") in lieu of director retainer fees of $19,000. The shares of Common Stock are fully vested. Julian C. Baker serves on the Issuer's Board of Directors (the "Board") as a representative of the Funds (as defined below).

F5 · ownership.nature: Pursuant to the policies of Baker Bros. Advisors LP (the "Adviser"), Julian C. Baker does not have any right to the pecuniary interest in the Issuer's securities issued in lieu of director retainer fees and the Funds (as defined below) are entitled to an indirect proportionate pecuniary interest in the securities. 667, L.P. ("667"), Baker Brothers Life Sciences, L.P. ("Life Sciences") and 14159, L.P. ("14159", and together with 667, and Life Sciences, the "Funds") each owns an indirect proportionate pecuniary interest in the shares of Common Stock. Solely as a result of their ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the shares of Common Stock issued in lieu of director retainer fees (ie. no direct pecuniary interest).

F7 · ownership.nature: As a result of Felix J. Baker's and Julian C. Baker's ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in 29,268,793 shares of common stock of the Issuer beneficially owned by Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences. Includes beneficial ownership of 3,156 shares issued pursuant to the Stock Incentive Plan in lieu of director retainer fees and 115,000 shares received previously from exercise of 115,000 stock options of the Issuer that were issued to Julian C. Baker in his capacity as a director of the Issuer, of which the fund may be deemed to own a portion.

F9 · ownership.nature: The Adviser serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are Managing Members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds.

F10 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F11 · ownership.nature: The 298 shares are reported for each of the Funds as each has an indirect pecuniary interest.

Read SEC document
December 31, 2018 Filed Jan 2, 2019 21:10 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
14159, L.P.Director · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
GrantCommon Stock 298 $63.59 $18,949.82
Disclosure

SEC source: 0001638599-19-000003 · doc4_5838.xml · nonDerivative · entry 4

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

14159, L.P. · CIK 0001551138 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,408,264

F4 · ownership.nature: 298 shares of common stock (the "Common Stock") issued to Julian C. Baker pursuant to the Issuer's Amended and Restated 2010 Stock Incentive Plan (the "Stock Incentive Plan") in lieu of director retainer fees of $19,000. The shares of Common Stock are fully vested. Julian C. Baker serves on the Issuer's Board of Directors (the "Board") as a representative of the Funds (as defined below).

F5 · ownership.nature: Pursuant to the policies of Baker Bros. Advisors LP (the "Adviser"), Julian C. Baker does not have any right to the pecuniary interest in the Issuer's securities issued in lieu of director retainer fees and the Funds (as defined below) are entitled to an indirect proportionate pecuniary interest in the securities. 667, L.P. ("667"), Baker Brothers Life Sciences, L.P. ("Life Sciences") and 14159, L.P. ("14159", and together with 667, and Life Sciences, the "Funds") each owns an indirect proportionate pecuniary interest in the shares of Common Stock. Solely as a result of their ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the shares of Common Stock issued in lieu of director retainer fees (ie. no direct pecuniary interest).

F6 · ownership.nature: As a result of Felix J. Baker's and Julian C. Baker's ownership interest in Baker Biotech Capital (GP), LLC, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in 4,408,264 shares of common stock of the Issuer beneficially owned by 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP),LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667. Includes beneficial ownership of 3,156 shares issued pursuant to the Stock Incentive Plan in lieu of director retainer fees and 115,000 shares received previously from exercise of 115,000 stock options of the Issuer that were issued to Julian C. Baker in his capacity as a director of the Issuer, of which the fund may be deemed to own a portion.

F9 · ownership.nature: The Adviser serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are Managing Members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds.

F10 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F11 · ownership.nature: The 298 shares are reported for each of the Funds as each has an indirect pecuniary interest.

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December 31, 2018 Filed Jan 3, 2019 21:12 UTC GrantCommon Stock 196 $63.59 $12,463.64
Disclosure

SEC source: 0001209191-19-000904 · doc4.xml · nonDerivative · entry 1

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 712

F1 · security: Restricted shares issued to the Reporting Person under the Issuer's Amended and Restated 2010 Stock Incentive Plan in lieu of quarterly director retainer fees pursuant to an election by the Reporting Person intended to comply with Rule 10b5-1. Restricted shares are fully vested.

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December 31, 2018 Filed Jan 3, 2019 21:08 UTC GrantCommon Stock 255 $63.59 $16,215.45
Disclosure

SEC source: 0001209191-19-000889 · doc4.xml · nonDerivative · entry 1

DIXON WENDY L · CIK 0001202283 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,199

F1 · security: Restricted shares issued to the Reporting Person under the Issuer's Amended and Restated 2010 Stock Incentive Plan in lieu of quarterly director retainer fees pursuant to an election by the Reporting Person intended to comply with Rule 10b5-1. Restricted shares are fully vested.

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December 31, 2018 Filed Jan 3, 2019 21:05 UTC GrantCommon Stock 373 $63.59 $23,719.07
Disclosure

SEC source: 0001209191-19-000880 · doc4.xml · nonDerivative · entry 1

BROOKE PAUL A · CIK 0001175940 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 198,929

F1 · security: Restricted shares issued to the Reporting Person under the Issuer's Amended and Restated 2010 Stock Incentive Plan in lieu of quarterly director retainer fees pursuant to an election by the Reporting Person intended to comply with Rule 10b5-1. Restricted shares are fully vested.

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December 31, 2018 Filed Jan 3, 2019 21:02 UTC GrantCommon Stock 228 $63.59 $14,498.52
Disclosure

SEC source: 0001209191-19-000858 · doc4.xml · nonDerivative · entry 1

BIENAIME JEAN JACQUES · CIK 0001221590 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,896

F1 · security: Restricted shares issued to the Reporting Person under the Issuer's Amended and Restated 2010 Stock Incentive Plan in lieu of quarterly director retainer fees pursuant to an election by the Reporting Person intended to comply with Rule 10b5-1. Restricted shares are fully vested.

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December 10, 2018 Filed Dec 12, 2018 21:10 UTC
Dhanak DashyantEVP & Chief Scientific Officer
GrantEmployee Stock Option (right to buy) · Derivative 48,403 $0.00 Strike: $65.42 $0.00
Disclosure

SEC source: 0001209191-18-062223 · doc4.xml · derivative · entry 2

Dhanak Dashyant · CIK 0001760682 · EVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,403

Underlying: Common Stock · 48,403 shares

Expires 2028-12-10

F2 · derivative.exercise_date: Beginning December 10, 2018, options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years.

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December 10, 2018 Filed Dec 12, 2018 21:10 UTC
Dhanak DashyantEVP & Chief Scientific Officer
GrantCommon Stock 6,878 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-062223 · doc4.xml · nonDerivative · entry 1

Dhanak Dashyant · CIK 0001760682 · EVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,878

F1 · shares: Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years, subject to Dr. Dashyant Dhanak's continued service with the issuer through the applicable vesting dates. The RSUs may be settled only for shares of common stock on a one-for-one basis.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.