IMCR

SEC source: 0001969518-26-000002 · form4-05282026_070511.xml · derivative · entry 1

Ratcliffe Peter John · CIK 0001969518 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001508596-26-000002 · form4-05282026_070509.xml · derivative · entry 1

Peterson Kristine · CIK 0001508596 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001919343-26-000002 · form4-05282026_070507.xml · derivative · entry 1

Pao William · CIK 0001919343 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001969522-26-000002 · form4-05282026_070505.xml · derivative · entry 1

Kaul Siddharth · CIK 0001969522 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001969520-26-000002 · form4-05282026_070503.xml · derivative · entry 1

Herbst Roy Steven · CIK 0001969520 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001969932-26-000002 · form4-05282026_070501.xml · derivative · entry 1

Bell John Irving · CIK 0001969932 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,492

Underlying: Ordinary Shares · 27,492 shares

Expires 2036-05-26

F1 · derivative.exercise_date: The shares subject to the option award shall vest at the earlier of (i) May 27, 2027 and (ii) the day immediately prior to the date of the Issuer's next annual general meeting, subject to the Reporting Person's continuous service through such vesting date.

SEC source: 0001730038-26-000002 · form4-02192026_050209.xml · nonDerivative · entry 2

Jallal Bahija · CIK 0001730038 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,343

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

F2 · shares: The shares were sold pursuant to a sell-to-cover arrangement for the purpose of satisfying income tax liabilities incurred upon vesting of restricted share units ("RSUs").

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.17 to $32.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001779466-26-000002 · form4-02192026_050207.xml · nonDerivative · entry 2

GOLL JOHN · CIK 0001779466 · SVP, FINANCE & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 653

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

F2 · shares: The shares were sold pursuant to a sell-to-cover arrangement for the purpose of satisfying income tax liabilities incurred upon vesting of restricted share units ("RSUs") .

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.18 to $32.72 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001969525-26-000002 · form4-02192026_050205.xml · nonDerivative · entry 2

St Leger Tina Amber · CIK 0001969525 · CHIEF HR OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,119

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

F2 · shares: The shares were sold pursuant to a sell-to-cover arrangement for the purpose of satisfying income tax liabilities incurred upon vesting of restricted stock units ("RSUs").

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.17 to $32.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-26-000002 · form4-02192026_050203.xml · nonDerivative · entry 2

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,859

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

F2 · shares: The shares were sold pursuant to a sell-to-cover arrangement for the purpose of satisfying income tax liabilities incurred upon vesting of restricted stock units ("RSUs").

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.17 to $32.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001969524-26-000002 · form4-02192026_100225.xml · derivative · entry 2

Coy Travis Alan · CIK 0001969524 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 95,637

Underlying: Ordinary Shares · 95,637 shares

Expires 2036-02-16

F4 · derivative.exercise_date: 25% of the shares subject to the option award shall vest on February 17, 2027, and 6.25% of the shares subject to the option award shall vest in quarterly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date.

F3 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001969524-26-000002 · form4-02192026_100225.xml · derivative · entry 1

Coy Travis Alan · CIK 0001969524 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,353

Underlying: Ordinary Shares · 33,353 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted share unit ("RSU") represents a contingent right to receive one Ordinary Share.

F2 · derivative.exercise_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F2 · derivative.expiration_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F3 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001730038-26-000002 · form4-02192026_050209.xml · derivative · entry 5

Jallal Bahija · CIK 0001730038 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 395,066

Underlying: Ordinary Shares · 395,066 shares

Expires 2036-02-16

F7 · derivative.exercise_date: 25% of the shares subject to the option award shall vest on February 17, 2027, and 6.25% of the shares subject to the option award shall vest in quarterly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001730038-26-000002 · form4-02192026_050209.xml · derivative · entry 4

Jallal Bahija · CIK 0001730038 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 88,573

Underlying: Ordinary Shares · 88,573 shares

Expires not disclosed

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F6 · derivative.exercise_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F6 · derivative.expiration_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001730038-26-000002 · form4-02192026_050209.xml · derivative · entry 3

Jallal Bahija · CIK 0001730038 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,453

Underlying: Ordinary Shares · 23,817 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F5 · derivative.exercise_date: On February 17, 2025, the Reporting Person was granted 95,270 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F5 · derivative.expiration_date: On February 17, 2025, the Reporting Person was granted 95,270 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001730038-26-000002 · form4-02192026_050209.xml · nonDerivative · entry 1

Jallal Bahija · CIK 0001730038 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,817

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001779466-26-000002 · form4-02192026_050207.xml · derivative · entry 5

GOLL JOHN · CIK 0001779466 · SVP, FINANCE & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,252

Underlying: Ordinary Shares · 21,252 shares

Expires 2036-02-16

F7 · derivative.exercise_date: 25% of the shares subject to the option award shall vest on February 17, 2027, and 6.25% of the shares subject to the option award shall vest in quarterly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001779466-26-000002 · form4-02192026_050207.xml · derivative · entry 4

GOLL JOHN · CIK 0001779466 · SVP, FINANCE & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,411

Underlying: Ordinary Shares · 7,411 shares

Expires not disclosed

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F6 · derivative.exercise_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F6 · derivative.expiration_date: The RSUs vest in four equal annual installments beginning February 17, 2027, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001779466-26-000002 · form4-02192026_050207.xml · derivative · entry 3

GOLL JOHN · CIK 0001779466 · SVP, FINANCE & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,054

Underlying: Ordinary Shares · 1,351 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F5 · derivative.exercise_date: On February 17, 2025, the Reporting Person was granted 5,405 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F5 · derivative.expiration_date: On February 17, 2025, the Reporting Person was granted 5,405 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001779466-26-000002 · form4-02192026_050207.xml · nonDerivative · entry 1

GOLL JOHN · CIK 0001779466 · SVP, FINANCE & CAO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,351

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001969525-26-000002 · form4-02192026_050205.xml · derivative · entry 3

St Leger Tina Amber · CIK 0001969525 · CHIEF HR OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,357

Underlying: Ordinary Shares · 2,119 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F5 · derivative.exercise_date: On February 17, 2025, the Reporting Person was granted 8,476 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F5 · derivative.expiration_date: On February 17, 2025, the Reporting Person was granted 8,476 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001969525-26-000002 · form4-02192026_050205.xml · nonDerivative · entry 1

St Leger Tina Amber · CIK 0001969525 · CHIEF HR OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,119

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001955244-26-000002 · form4-02192026_050203.xml · derivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,473

Underlying: Ordinary Shares · 11,824 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each RSU represents a contingent right to receive one Ordinary Share.

F5 · derivative.exercise_date: On February 17, 2025, the Reporting Person was granted 47,297 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F5 · derivative.expiration_date: On February 17, 2025, the Reporting Person was granted 47,297 RSUs, vesting in four equal annual installments beginning February 17, 2026, subject to the Reporting Person's continuous service through each such vesting date.

F1 · derivative.underlying: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001955244-26-000002 · form4-02192026_050203.xml · nonDerivative · entry 1

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,824

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Ordinary Shares may be represented by American Depositary Shares. Each American Depositary Share represents one Ordinary Share.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · derivative · entry 6

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,832

Underlying: Ordinary Shares · 572 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F4 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · nonDerivative · entry 4

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.21 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · nonDerivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 572

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · derivative · entry 5

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,404

Underlying: Ordinary Shares · 31,341 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F4 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · nonDerivative · entry 2

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.02 to $40.44 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000015 · form4-12082025_041211.xml · nonDerivative · entry 1

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,341

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · derivative · entry 6

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 43,745

Underlying: Ordinary Shares · 5,521 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F4 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · nonDerivative · entry 4

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.30 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · nonDerivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,521

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · derivative · entry 5

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 49,266

Underlying: Ordinary Shares · 69,404 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F4 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · nonDerivative · entry 2

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.40 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000013 · form4-12012025_041201.xml · nonDerivative · entry 1

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,404

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · derivative · entry 6

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,670

Underlying: Ordinary Shares · 18,020 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · nonDerivative · entry 4

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.17 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · nonDerivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,020

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · derivative · entry 5

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136,690

Underlying: Ordinary Shares · 100 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · nonDerivative · entry 2

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000011 · form4-11262025_091110.xml · nonDerivative · entry 1

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 100

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000008 · form4-10022025_041002.xml · derivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136,790

Underlying: Ordinary Shares · 61,849 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000008 · form4-10022025_041002.xml · nonDerivative · entry 2

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.01 to $35.48 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000008 · form4-10022025_041002.xml · nonDerivative · entry 1

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,849

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000005 · form4-09162025_040906.xml · derivative · entry 7

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 198,639

Underlying: Ordinary Shares · 200 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F5 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000005 · form4-09162025_040906.xml · nonDerivative · entry 5

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.00 to $35.01 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001955244-25-000005 · form4-09162025_040906.xml · nonDerivative · entry 4

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

SEC source: 0001955244-25-000005 · form4-09162025_040906.xml · derivative · entry 6

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 198,839

Underlying: Ordinary Shares · 22,532 shares

Expires 2028-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F5 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001955244-25-000005 · form4-09162025_040906.xml · nonDerivative · entry 3

Berman David M · CIK 0001955244 · HEAD OF R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 9, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.22 to $36.52 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.