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HERON THERAPEUTICS, INC. /DE/

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SEC CIK
0000818033
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288

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
April 19, 2026 Filed Apr 21, 2026 15:15 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionRestricted Stock Units · Derivative 3,874 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-165591 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,120

Underlying: Common Stock · 3,874 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
April 19, 2026 Filed Apr 21, 2026 15:15 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionCommon Stock 3,874 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-165591 · ownership.xml · nonDerivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 185,647

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
April 19, 2026 Filed Apr 21, 2026 13:41 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 13,797 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-165365 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,758

Underlying: Common Stock · 13,797 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
April 19, 2026 Filed Apr 21, 2026 13:41 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 13,797 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-165365 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 662,052

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
April 19, 2026 Filed Apr 21, 2026 13:13 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 3,874 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-165304 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,120

Underlying: Common Stock · 3,874 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F3 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
April 19, 2026 Filed Apr 21, 2026 13:13 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionCommon Stock 3,874 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-165304 · ownership.xml · nonDerivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 215,876

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · balance_after: Includes 16,646 shares acquired under the Heron Therapeutics, Inc. 1997 Employee Stock Purchase Plan on April 30, 2025.

Read SEC document
April 03, 2026 Filed Apr 6, 2026 23:06 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 62,500 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-144196 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,500

Underlying: Common Stock · 62,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning one year after the date of grant, subject to the Reporting Person's continued service to the Issuer through the vesting date.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning one year after the date of grant, subject to the Reporting Person's continued service to the Issuer through the vesting date.

Read SEC document
April 03, 2026 Filed Apr 6, 2026 23:06 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 62,500 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-144196 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 648,255

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · balance_after: Includes 14,045 shares acquired under the Heron Therapeutics, Inc. 1997 Employee Stock Purchase Plan on April 30, 2025.

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 11,695 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034492 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 140,332

Underlying: Common Stock · 11,695 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionCommon Stock 11,695 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-034492 · ownership.xml · nonDerivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,356

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionRestricted Stock Units · Derivative 11,695 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034491 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 140,332

Underlying: Common Stock · 11,695 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionCommon Stock 11,695 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-034491 · ownership.xml · nonDerivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 181,773

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 34,789 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034490 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 417,464

Underlying: Common Stock · 34,789 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
January 31, 2026 Filed Feb 3, 2026 13:30 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 34,789 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-034490 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 571,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Collard Craig ADirector · Chief Executive Officer
GrantPerformance Stock Units · Derivative 800,336 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034633 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 800,336

Underlying: Common Stock · 800,336 shares

Expires not disclosed

F3 · derivative.exercise_price: Performance stock units ("PSUs") convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: On January 30, 2026, the Reporting Person was granted 800,336 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

F4 · derivative.expiration_date: On January 30, 2026, the Reporting Person was granted 800,336 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Collard Craig ADirector · Chief Executive Officer
GrantRestricted Stock Units · Derivative 800,337 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034633 · ownership.xml · derivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 800,337

Underlying: Common Stock · 800,337 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units ("RSUs") convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 800,337 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

F2 · derivative.expiration_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 800,337 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034632 · ownership.xml · nonDerivative · entry 1

Christian Waage · CIK 0001553179 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,960

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contigent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034631 · ownership.xml · nonDerivative · entry 1

Kaseta Michael · CIK 0001724346 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,960

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contigent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Duarte IraEVP, Chief Financial Officer
GrantPerformance Stock Units · Derivative 216,561 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034630 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 216,561

Underlying: Common Stock · 216,561 shares

Expires not disclosed

F3 · derivative.exercise_price: Performance stock units ("PSUs") convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: On January 30, 2026, the Reporting Person was granted 216,561 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

F4 · derivative.expiration_date: On January 30, 2026, the Reporting Person was granted 216,561 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Duarte IraEVP, Chief Financial Officer
GrantRestricted Stock Units · Derivative 216,562 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034630 · ownership.xml · derivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 216,562

Underlying: Common Stock · 216,562 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units ("RSUs") convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 216,562 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

F2 · derivative.expiration_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 216,562 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034629 · ownership.xml · nonDerivative · entry 1

Johnson Craig A · CIK 0001370348 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,960

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contigent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034628 · ownership.xml · nonDerivative · entry 1

Cusack Thomas · CIK 0002094824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,960

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contigent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Forbes William PEVP, Chief Development Officer
GrantPerformance Stock Units · Derivative 188,314 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034627 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 188,314

Underlying: Common Stock · 188,314 shares

Expires not disclosed

F3 · derivative.exercise_price: Performance stock units ("PSUs") convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: On January 30, 2026, the Reporting Person was granted 188,314 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

F4 · derivative.expiration_date: On January 30, 2026, the Reporting Person was granted 188,314 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Forbes William PEVP, Chief Development Officer
GrantRestricted Stock Units · Derivative 188,315 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034627 · ownership.xml · derivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 188,315

Underlying: Common Stock · 188,315 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units ("RSUs") convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 188,315 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

F2 · derivative.expiration_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 188,315 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034626 · ownership.xml · nonDerivative · entry 1

Dissanaike Sharmila · CIK 0001885069 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,960

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contigent right to receive one share of common stock.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Hensley Mark EarlChief Operating Officer
GrantPerformance Stock Units · Derivative 188,314 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034625 · ownership.xml · derivative · entry 2

Hensley Mark Earl · CIK 0002065816 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 188,314

Underlying: Common Stock · 188,314 shares

Expires not disclosed

F3 · derivative.exercise_price: Performance stock units ("PSUs") convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: On January 30, 2026, the Reporting Person was granted 188,314 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

F4 · derivative.expiration_date: On January 30, 2026, the Reporting Person was granted 188,314 PSUs which vest upon the following time-based vesting schedule: the PSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant, subject to satisfaction of the milestone-based vesting condition: the applicable percentage of the PSUs vesting based on a net product sales revenue target for the fiscal year ending December 31, 2026 as reported in the Issuer's Form 10-K. The full amount of the PSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 15:00 UTC
Hensley Mark EarlChief Operating Officer
GrantRestricted Stock Units · Derivative 188,315 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-034625 · ownership.xml · derivative · entry 1

Hensley Mark Earl · CIK 0002065816 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 188,315

Underlying: Common Stock · 188,315 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units ("RSUs") convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 188,315 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

F2 · derivative.expiration_date: On January 30, 2026 (the "Date of Grant"), the Reporting Person was granted 188,315 RSUs which vest upon the following time-based vesting schedule: the RSUs vest in 16 equal quarterly installments beginning one quarter after the Date of Grant. The full amount of the RSUs granted to the Reporting Person is reflected herein.

Read SEC document
January 30, 2026 Filed Feb 3, 2026 14:15 UTC
Morgan AdamDirector
GrantCommon Stock 53,960 $0.00 $0.00
Disclosure

SEC source: 0000921895-26-000200 · form412927018_02032026.xml · nonDerivative · entry 1

Morgan Adam · CIK 0001964335 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 123,737

F1 · shares: The shares were granted as restricted stock units which vest in full on January 30, 2027. Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 19, 2026 Filed Jan 20, 2026 20:00 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionRestricted Stock Units · Derivative 3,875 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-016451 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,994

Underlying: Common Stock · 3,875 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
January 19, 2026 Filed Jan 20, 2026 20:00 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionCommon Stock 3,875 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-016451 · ownership.xml · nonDerivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 170,078

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 19, 2026 Filed Jan 20, 2026 19:49 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 3,875 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-016423 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,994

Underlying: Common Stock · 3,875 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
January 19, 2026 Filed Jan 20, 2026 19:49 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionCommon Stock 3,875 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-016423 · ownership.xml · nonDerivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 183,661

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
January 19, 2026 Filed Jan 20, 2026 19:39 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 13,797 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-26-016413 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 110,375

Underlying: Common Stock · 13,797 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
January 19, 2026 Filed Jan 20, 2026 19:39 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 13,797 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-016413 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 536,921

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
November 08, 2025 Filed Nov 12, 2025 14:20 UTC GrantStock Option (Right to Buy) · Derivative 227,272 $1.10 Strike: $1.10 $249,999.20
Disclosure

SEC source: 0001193125-25-276244 · ownership.xml · derivative · entry 2

Cusack Thomas · CIK 0002094824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 227,272

Underlying: Common Stock · 227,272 shares

Expires 2035-11-08

F3 · derivative.exercise_date: The stock options vest and become exercisable in 48 equal monthly installments beginning one month after the date of grant.

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November 08, 2025 Filed Nov 12, 2025 14:20 UTC GrantCommon Stock 37,879 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-276244 · ownership.xml · nonDerivative · entry 1

Cusack Thomas · CIK 0002094824 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,879

F1 · security: The shares were granted as restricted stock units which vest in 16 equal quarterly installments beginning one quarter after the date of grant.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:35 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionRestricted Stock Units · Derivative 11,694 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-264044 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 152,027

Underlying: Common Stock · 11,694 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:35 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionCommon Stock 11,694 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-264044 · ownership.xml · nonDerivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 166,203

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:33 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 11,694 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-264039 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 152,027

Underlying: Common Stock · 11,694 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:33 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionCommon Stock 11,694 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-264039 · ownership.xml · nonDerivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 179,786

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:31 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 34,789 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-264032 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 452,253

Underlying: Common Stock · 34,789 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal installments beginning one quarter after the date of grant (January 31, 2025).

Read SEC document
October 31, 2025 Filed Nov 4, 2025 17:31 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 34,789 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-264032 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 523,124

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:56 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionRestricted Stock Units · Derivative 3,874 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-244582 · ownership.xml · derivative · entry 2

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,869

Underlying: Common Stock · 3,874 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:56 UTC
Forbes William PEVP, Chief Development Officer
Exercise / conversionCommon Stock 3,874 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-244582 · ownership.xml · nonDerivative · entry 1

Forbes William P · CIK 0001314760 · EVP, Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,509

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:42 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 3,874 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-244560 · ownership.xml · derivative · entry 2

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,869

Underlying: Common Stock · 3,874 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:42 UTC
Duarte IraEVP, Chief Financial Officer
Exercise / conversionCommon Stock 3,874 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-244560 · ownership.xml · nonDerivative · entry 1

Duarte Ira · CIK 0001488864 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 168,092

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:23 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 13,797 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001193125-25-244520 · ownership.xml · derivative · entry 2

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,172

Underlying: Common Stock · 13,797 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

F2 · derivative.expiration_date: The restricted stock units vest in 16 equal quarterly installments beginning one quarter after the date of grant (01/19/2024).

Read SEC document
October 19, 2025 Filed Oct 21, 2025 15:23 UTC
Collard Craig ADirector · Chief Executive Officer
Exercise / conversionCommon Stock 13,797 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-25-244520 · ownership.xml · nonDerivative · entry 1

Collard Craig A · CIK 0001363558 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 488,335

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

Read SEC document
October 15, 2025 Filed Oct 17, 2025 22:00 UTC ConversionSeries A Convertible Preferred Stock ("Preferred Shares") · Derivative 94,610 $0.00 $0.00
Disclosure

SEC source: 0000902664-25-004459 · ownership.xml · derivative · entry 2

Rubric Capital Management LP · CIK 0001687509 · 10% owner

Rosen David Efraim · CIK 0001898677 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 946,100 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Preferred Shares automatically converted into Common Stock pursuant to their terms at a conversion price of $1.50.

F1 · derivative.exercise_date: The Preferred Shares automatically converted into Common Stock pursuant to their terms at a conversion price of $1.50.

F1 · derivative.expiration_date: The Preferred Shares automatically converted into Common Stock pursuant to their terms at a conversion price of $1.50.

F2 · ownership.nature: This Form 4 is filed by Rubric Capital Management LP ("Rubric Capital") and Mr. David Rosen, with respect to the securities held by certain funds and/or accounts (collectively, the "Rubric Vehicles"). Rubric Capital serves as the investment adviser to the Rubric Vehicles. Mr. David Rosen serves as the Managing Member of Rubric Capital Management GP, LLC, the general partner of Rubric Capital.

F3 · ownership.nature: The filing of this statement shall not be deemed an admission that any Reporting Person is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each Reporting Person expressly disclaims beneficial ownership of the securities reported herein except to the extent of its or his pecuniary interest therein.

Read SEC document
October 15, 2025 Filed Oct 17, 2025 22:00 UTC ConversionCommon Stock, par value $0.01 per share ("Common Stock") 946,100 Not disclosed Not disclosed
Disclosure

SEC source: 0000902664-25-004459 · ownership.xml · nonDerivative · entry 1

Rubric Capital Management LP · CIK 0001687509 · 10% owner

Rosen David Efraim · CIK 0001898677 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 30,046,828

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Preferred Shares automatically converted into Common Stock pursuant to their terms at a conversion price of $1.50.

F2 · ownership.nature: This Form 4 is filed by Rubric Capital Management LP ("Rubric Capital") and Mr. David Rosen, with respect to the securities held by certain funds and/or accounts (collectively, the "Rubric Vehicles"). Rubric Capital serves as the investment adviser to the Rubric Vehicles. Mr. David Rosen serves as the Managing Member of Rubric Capital Management GP, LLC, the general partner of Rubric Capital.

F3 · ownership.nature: The filing of this statement shall not be deemed an admission that any Reporting Person is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each Reporting Person expressly disclaims beneficial ownership of the securities reported herein except to the extent of its or his pecuniary interest therein.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.