HRMY

SEC source: 0000899243-21-032526 · doc4.xml · nonDerivative · entry 2

Dayno Jeffrey M. · CIK 0001615993 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.00 to $30.75. The reporting person undertakes to provide the Issuer, any securityholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000899243-21-032526 · doc4.xml · nonDerivative · entry 1

Dayno Jeffrey M. · CIK 0001615993 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,950

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-21-029687 · doc4.xml · derivative · entry 3

Dayno Jeffrey M. · CIK 0001615993 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,419

Underlying: Common Stock · 50 shares

Expires 2027-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option is currently vested with respect to 82,777 shares, and will vest with respect to the remainder of the shares in two equal annual installments beginning on October 13, 2021.

SEC source: 0000899243-21-029687 · doc4.xml · nonDerivative · entry 2

Dayno Jeffrey M. · CIK 0001615993 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan.

SEC source: 0000899243-21-029687 · doc4.xml · nonDerivative · entry 1

Dayno Jeffrey M. · CIK 0001615993 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-21-024214 · doc4.xml · derivative · entry 3

Dierks Jeffrey · CIK 0001821102 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,692

Underlying: Common Stock · 15,000 shares

Expires 2027-10-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option is currently vested with respect to 20,707 shares, and will vest with respect to the remainder of the shares in two equal annual installments beginning on October 2, 2021.

SEC source: 0000899243-21-024214 · doc4.xml · nonDerivative · entry 2

Dierks Jeffrey · CIK 0001821102 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.96 to $31.73. The reporting person undertakes to provide the issuer, any security holder of the Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000899243-21-024214 · doc4.xml · nonDerivative · entry 1

Dierks Jeffrey · CIK 0001821102 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-21-023896 · doc4.xml · derivative · entry 1

Dierks Jeffrey · CIK 0001821102 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,900

Underlying: Common Stock · 53,900 shares

Expires 2031-06-01

F1 · derivative.exercise_date: The stock option shall vest with respect to half of the underlying shares on June 1, 2022 and with respect to the remaining shares, in forty-eight equal monthly installments beginning on July 1, 2022.

SEC source: 0000899243-21-023568 · doc4.xml · derivative · entry 1

Gracias Antonio J. · CIK 0001495158 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,144

Underlying: Common Stock · 10,144 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-023564 · doc4.xml · derivative · entry 1

Graf R. Mark · CIK 0001494757 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,246

Underlying: Common Stock · 7,246 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-023566 · doc4.xml · derivative · entry 1

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,246

Underlying: Common Stock · 7,246 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-023567 · doc4.xml · derivative · entry 1

Sender Gary · CIK 0001659085 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,333

Underlying: Common Stock · 13,333 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-023565 · doc4.xml · derivative · entry 1

Motley Eric L · CIK 0001831815 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,246

Underlying: Common Stock · 7,246 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-023563 · doc4.xml · derivative · entry 1

Sabater Juan A. · CIK 0001821210 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,246

Underlying: Common Stock · 7,246 shares

Expires 2031-05-20

F1 · derivative.exercise_date: The stock option shall vest in full on the earlier to occur of (i) May 20, 2022 and (ii) the date of the next annual meeting following the grant date, subject to continued service through the applicable vesting date.

SEC source: 0000899243-21-014161 · doc4.xml · derivative · entry 2

Kapadia Sandip · CIK 0001677141 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 230,000

Underlying: Common Stock · 230,000 shares

Expires 2031-03-29

F2 · derivative.exercise_date: The stock option vests with respect to 50% of the underlying shares on March 29, 2023, and will vest with respect to the remainder of the shares in 24 equal monthly installments thereafter.

SEC source: 0000899243-21-014161 · doc4.xml · derivative · entry 1

Kapadia Sandip · CIK 0001677141 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Represents an award of restricted stock units, which will vest with respect to 50% of the underlying shares on March 29, 2023, and in two equal annual installments thereafter. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date.

F1 · derivative.exercise_date: Represents an award of restricted stock units, which will vest with respect to 50% of the underlying shares on March 29, 2023, and in two equal annual installments thereafter. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date.

F1 · derivative.expiration_date: Represents an award of restricted stock units, which will vest with respect to 50% of the underlying shares on March 29, 2023, and in two equal annual installments thereafter. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date.

SEC source: 0000899243-20-030987 · doc4.xml · derivative · entry 1

Graf R. Mark · CIK 0001494757 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,604

Underlying: Common Stock · 4,604 shares

Expires 2030-11-11

F1 · derivative.exercise_date: The stock option shall vest in 36 equal monthly installments beginning on December 11, 2020.

SEC source: 0000899243-20-030988 · doc4.xml · derivative · entry 1

Motley Eric L · CIK 0001831815 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,604

Underlying: Common Stock · 4,604 shares

Expires 2030-11-11

F1 · derivative.exercise_date: The stock option shall vest in 36 equal monthly installments beginning on December 11, 2020.

SEC source: 0000899243-20-023547 · doc4.xml · nonDerivative · entry 2

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 42,702

F3 · price: The price reported herein is a weighted average price. These shares were acquired on the open market in multiple transactions at prices ranging from $33.9 to $35.0, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the ranges set forth in footnote (3) to this Form 4.

F1 · ownership.nature: The shares are held of record by Vivo Capital Fund IX, L.P. Vivo Capital IX, LLC is the General Partner of Vivo Capital Fund IX, L.P. As a managing member of Vivo Capital IX, LLC, Jack Nielsen shares voting and dispositive power with respect to the shares held of record by Vivo Capital Fund IX, L.P with other managing members, but disclaims beneficial ownership of such shares except to the extent of his individual pecuniary interest therein.

SEC source: 0000899243-20-023547 · doc4.xml · nonDerivative · entry 1

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 38,780

F2 · price: The price reported herein is a weighted average price. These shares were acquired on the open market in multiple transactions at prices ranging from $33.3 to $34.8, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the ranges set forth in footnote (2) to this Form 4.

F1 · ownership.nature: The shares are held of record by Vivo Capital Fund IX, L.P. Vivo Capital IX, LLC is the General Partner of Vivo Capital Fund IX, L.P. As a managing member of Vivo Capital IX, LLC, Jack Nielsen shares voting and dispositive power with respect to the shares held of record by Vivo Capital Fund IX, L.P with other managing members, but disclaims beneficial ownership of such shares except to the extent of his individual pecuniary interest therein.

SEC source: 0000899243-20-023341 · doc4.xml · nonDerivative · entry 4

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 37,957

F4 · price: The price reported herein is a weighted average price. These shares were acquired on the open market in multiple transactions at prices ranging from $35.0 to $33.8, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the ranges set forth in footnote (4) to this Form 4.

F1 · ownership.nature: The shares are held of record by Vivo Capital Fund IX, L.P. Vivo Capital IX, LLC is the General Partner of Vivo Capital Fund IX, L.P. As a managing member of Vivo Capital IX, LLC, Jack Nielsen shares voting and dispositive power with respect to the shares held of record by Vivo Capital Fund IX, L.P with other managing members, but disclaims beneficial ownership of such shares except to the extent of his individual pecuniary interest therein.

SEC source: 0000899243-20-023341 · doc4.xml · nonDerivative · entry 3

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 34,900

F3 · price: The price reported herein is a weighted average price. These shares were acquired on the open market in multiple transactions at prices ranging from $33.3 to $35.0, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the ranges set forth in footnote (3) to this Form 4.

F1 · ownership.nature: The shares are held of record by Vivo Capital Fund IX, L.P. Vivo Capital IX, LLC is the General Partner of Vivo Capital Fund IX, L.P. As a managing member of Vivo Capital IX, LLC, Jack Nielsen shares voting and dispositive power with respect to the shares held of record by Vivo Capital Fund IX, L.P with other managing members, but disclaims beneficial ownership of such shares except to the extent of his individual pecuniary interest therein.

SEC source: 0000899243-20-023341 · doc4.xml · nonDerivative · entry 2

Nielsen Jack · CIK 0001602402 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 27,548

F2 · price: The price reported herein is the public offering price.

F1 · ownership.nature: The shares are held of record by Vivo Capital Fund IX, L.P. Vivo Capital IX, LLC is the General Partner of Vivo Capital Fund IX, L.P. As a managing member of Vivo Capital IX, LLC, Jack Nielsen shares voting and dispositive power with respect to the shares held of record by Vivo Capital Fund IX, L.P with other managing members, but disclaims beneficial ownership of such shares except to the extent of his individual pecuniary interest therein.

SEC source: 0000899243-20-023393 · doc4.xml · derivative · entry 4

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 240,668 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F4 · shares: Includes 23,141 shares received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

F1 · derivative.exercise_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F4 · derivative.underlying_shares: Includes 23,141 shares received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-023393 · doc4.xml · derivative · entry 3

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 12,080,352 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F3 · shares: Includes 2,950,712 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

F1 · derivative.exercise_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F3 · derivative.underlying_shares: Includes 2,950,712 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-023393 · doc4.xml · nonDerivative · entry 2

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,166,357

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-023393 · doc4.xml · nonDerivative · entry 1

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,925,688

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0001209191-20-048226 · doc4.xml · derivative · entry 4

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 250,516 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · price: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.exercise_date: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.expiration_date: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0001209191-20-048226 · doc4.xml · derivative · entry 3

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,026,784 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · price: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.exercise_date: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.expiration_date: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0001209191-20-048226 · doc4.xml · nonDerivative · entry 2

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,409,803

F2 · shares: Represents a purchase from the underwriters in the Issuer's initial public offering.

SEC source: 0001209191-20-048226 · doc4.xml · nonDerivative · entry 1

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,277,300

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0000899243-20-023394 · doc4.xml · derivative · entry 4

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,871 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F3 · shares: Includes 661 shares received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F3 · derivative.underlying_shares: Includes 661 shares received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-023394 · doc4.xml · derivative · entry 3

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 32,214 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F2 · shares: Includes 7,869 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

F2 · derivative.underlying_shares: Includes 7,869 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-023394 · doc4.xml · nonDerivative · entry 2

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,085

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

SEC source: 0000899243-20-023394 · doc4.xml · nonDerivative · entry 1

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,214

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a one-for-one basis into Common stock upon the closing of the Issuer's initial public offering.

SEC source: 0000899243-20-023396 · doc4.xml · derivative · entry 2

Marshman Fund Trust II · CIK 0001821461 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,026,784 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F2 · shares: Includes 983,571 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

F1 · derivative.exercise_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

F2 · derivative.underlying_shares: Includes 983,571 shares received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-023396 · doc4.xml · nonDerivative · entry 1

Marshman Fund Trust II · CIK 0001821461 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,958,547

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preffered stock automatically converted on a 8.215-for-1 basis into common stock upon the closing of the Issuer's initial public offering.

SEC source: 0000899243-20-024369 · doc4a.xml · derivative · entry 4

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 233,052.23 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F4 · derivative.underlying_shares: Includes 15,525.15 shares of common stock received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-024369 · doc4a.xml · derivative · entry 3

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,139,645.04 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F3 · derivative.underlying_shares: Includes 1,010,004.14 shares of common stock received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-024369 · doc4a.xml · nonDerivative · entry 2

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,218,033

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0000899243-20-024369 · doc4a.xml · nonDerivative · entry 1

Valor IV Pharma Holdings, LLC · CIK 0001821186 · 10% owner

Valor Management L.P. · CIK 0001822428 · 10% owner

Valor Equity Capital IV LLC · CIK 0001821936 · 10% owner

Valor Equity Associates IV L.P. · CIK 0001822427 · 10% owner

VALOR EQUITY PARTNERS IV L.P. · CIK 0001705506 · 10% owner

VALOR EQUITY PARTNERS IV-A L.P. · CIK 0001705542 · 10% owner

VALOR EQUITY PARTNERS IV-B L.P. · CIK 0001705512 · 10% owner

Gracias Antonio J. · CIK 0001495158 · Director · 10% owner

Sabater Juan A. · CIK 0001821210 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,984,981

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F2 · ownership.direct: Antonio Gracias is the Chief Executive Officer of Valor Management L.P. ("Valor Management") and Juan A. Sabater is the President of Valor Management. Valor Management is the managing member of Valor Equity Capital IV LLC, which is the general partner of Valor Equity Associates IV L.P., which, in turn, is the general partner of each of Valor Equity Partners IV L.P., Valor Equity Partners IV-A L.P. and Valor Equity Partners IV-B L.P. (collectively, the "Valor Funds"). The Valor Funds are the sole members of the Valor IV Pharma Holdings, LLC ("Valor"). As such, Messers. Gracias and Sabater may be deemed to beneficially own the shares held by Valor. Each of Messers. Gracias and Sabater disclaims beneficial ownership over the shares described herein except to the extent of their pecuniary interest therein.

SEC source: 0001209191-20-049626 · doc4a.xml · derivative · entry 3

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 242,588 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · price: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.exercise_date: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.expiration_date: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0001209191-20-049626 · doc4a.xml · derivative · entry 2

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,379,882 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · price: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.exercise_date: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

F1 · derivative.expiration_date: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0001209191-20-049626 · doc4a.xml · nonDerivative · entry 1

Novo Holdings A/S · CIK 0001388325 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,754,973

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: This amendment reflects the updated dividend shares issuable on the preferred stock as communicated to Novo Holdings A/S by the Issuer on August 31, 2020. The Series A Convertible Preferred Stock and Series C Convertible Preferred Stock automatically converted on a 8.215-for-1 basis into the number of shares of Common Stock as shown in Column 7 upon the closing of the Issuer's initial public offering without payment or further consideration. The number of shares of Common Stock shown in Column 7 also includes the payment of an accrued stock dividend by the Company to the holder which became due and issuable upon the conversion of the convertible preferred stock. These shares have no expiration date.

SEC source: 0000899243-20-024372 · doc4a.xml · derivative · entry 2

Marshman Fund Trust II · CIK 0001821461 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,379,881.68 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F2 · derivative.underlying_shares: Includes 336,668.05 shares of common stock received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-024372 · doc4a.xml · nonDerivative · entry 1

Marshman Fund Trust II · CIK 0001821461 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,379,881

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

SEC source: 0000899243-20-024370 · doc4a.xml · derivative · entry 3

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,653.98 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F3 · derivative.underlying_shares: Includes 443.27 shares of common stock received upon the payment of an in-kind dividend on the Series C Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-024370 · doc4a.xml · derivative · entry 2

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 27,039.05 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.exercise_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F1 · derivative.expiration_date: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.

F2 · derivative.underlying_shares: Includes 2,693.34 shares of common stock received upon the payment of an in-kind dividend on the Series A Preferred Stock on August 21, 2020.

SEC source: 0000899243-20-024370 · doc4a.xml · nonDerivative · entry 1

Serafin Andrew · CIK 0001821460 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,693

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of preferred stock automatically converted on a 8.215-for-one basis into common stock upon the closing of the Issuer's initial public offering, with any fractional shares resulting from the conversion of the aggregate preferred stock held by the reporting person canceled in exchange for cash.