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GPCR

Structure Therapeutics Inc.

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1222
SEC CIK
0001888886
Parsed reports
115

Last 12 months

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Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202600
Mar 202600
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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 19, 2026 Filed Mar 23, 2026 16:30 UTC
Coll Crespo BlasCHIEF MEDICAL OFFICER
GrantOrdinary Shares 75,897 $0.00 $0.00
Disclosure

SEC source: 0002037144-26-000003 · form4-03232026_040308.xml · nonDerivative · entry 1

Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 280,878

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 16:30 UTC
Hall AshleyChief Development Officer
GrantEmployee Stock Option (right to buy) · Derivative 59,073 $0.00 Strike: $16.82 $0.00
Disclosure

SEC source: 0001801842-26-000003 · form4-03232026_040310.xml · derivative · entry 2

Hall Ashley · CIK 0001801842 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,073

Underlying: Ordinary Shares · 59,073 shares

Expires 2036-03-18

F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.

F4 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 16:30 UTC
Hall AshleyChief Development Officer
GrantOrdinary Shares 47,706 $0.00 $0.00
Disclosure

SEC source: 0001801842-26-000003 · form4-03232026_040310.xml · nonDerivative · entry 1

Hall Ashley · CIK 0001801842 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 155,187

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one ordinary share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
GrantEmployee Stock Option (right to buy) · Derivative 322,230 $0.00 Strike: $16.82 $0.00
Disclosure

SEC source: 0001698149-26-000003 · form4-03232026_040301.xml · derivative · entry 3

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 322,230

Underlying: Ordinary Shares · 322,230 shares

Expires 2036-03-18

F4 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.

F5 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
GrantOrdinary Shares 260,217 $0.00 $0.00
Disclosure

SEC source: 0001698149-26-000003 · form4-03232026_040301.xml · nonDerivative · entry 1

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,401,593

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Ma YingliCHIEF TECHNOLOGY OFFICER
GrantEmployee Stock Option (right to buy) · Derivative 40,278 $0.00 Strike: $16.82 $0.00
Disclosure

SEC source: 0001963664-26-000003 · form4-03232026_040307.xml · derivative · entry 2

Ma Yingli · CIK 0001963664 · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,278

Underlying: Ordinary Shares · 40,278 shares

Expires 2036-03-18

F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.

F4 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Ma YingliCHIEF TECHNOLOGY OFFICER
GrantOrdinary Shares 32,526 $0.00 $0.00
Disclosure

SEC source: 0001963664-26-000003 · form4-03232026_040307.xml · nonDerivative · entry 1

Ma Yingli · CIK 0001963664 · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 139,917

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one ordinary share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Lin XichenCHIEF SCIENTIFIC OFFICER
GrantEmployee Stock Option (right to buy) · Derivative 53,703 $0.00 Strike: $16.82 $0.00
Disclosure

SEC source: 0001962926-26-000003 · form4-03232026_040305.xml · derivative · entry 2

Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,703

Underlying: Ordinary Shares · 53,703 shares

Expires 2036-03-18

F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.

F4 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Lin XichenCHIEF SCIENTIFIC OFFICER
GrantOrdinary Shares 43,368 $0.00 $0.00
Disclosure

SEC source: 0001962926-26-000003 · form4-03232026_040305.xml · nonDerivative · entry 1

Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 228,960

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one ordinary share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Yoon JunCHIEF FINANCIAL OFFICER
GrantEmployee Stock Option (right to buy) · Derivative 128,892 $0.00 Strike: $16.82 $0.00
Disclosure

SEC source: 0001962414-26-000003 · form4-03232026_040303.xml · derivative · entry 3

Yoon Jun · CIK 0001962414 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 128,892

Underlying: Ordinary Shares · 128,892 shares

Expires 2036-03-18

F4 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.

F5 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 20:30 UTC
Yoon JunCHIEF FINANCIAL OFFICER
GrantOrdinary Shares 104,085 $0.00 $0.00
Disclosure

SEC source: 0001962414-26-000003 · form4-03232026_040303.xml · nonDerivative · entry 1

Yoon Jun · CIK 0001962414 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,401,656

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2026, subject to Reporting Person's continued service on such dates.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 18:20 UTC
Coll Crespo BlasCHIEF MEDICAL OFFICER
Tax withholdingOrdinary Shares 11,826 $20.99 $248,227.74
Disclosure

SEC source: 0002037144-26-000002 · form4-03052026_060312.xml · nonDerivative · entry 1

Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 204,981

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 18:20 UTC
Hall AshleyChief Development Officer
Tax withholdingOrdinary Shares 4,836 $20.99 $101,507.64
Disclosure

SEC source: 0001801842-26-000002 · form4-03052026_060304.xml · nonDerivative · entry 1

Hall Ashley · CIK 0001801842 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,481

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 23:20 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
Tax withholdingOrdinary Shares 53,454 $20.99 $1,121,999.46
Disclosure

SEC source: 0001698149-26-000002 · form4-03052026_060301.xml · nonDerivative · entry 1

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,141,376

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 23:20 UTC
Ma YingliCHIEF TECHNOLOGY OFFICER
Tax withholdingOrdinary Shares 11,313 $20.99 $237,459.87
Disclosure

SEC source: 0001963664-26-000002 · form4-03052026_060310.xml · nonDerivative · entry 1

Ma Yingli · CIK 0001963664 · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,391

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 23:20 UTC
Lin XichenCHIEF SCIENTIFIC OFFICER
Tax withholdingOrdinary Shares 18,735 $20.99 $393,247.65
Disclosure

SEC source: 0001962926-26-000002 · form4-03052026_060307.xml · nonDerivative · entry 1

Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 185,592

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 23:20 UTC
Yoon JunCHIEF FINANCIAL OFFICER
Tax withholdingOrdinary Shares 22,305 $20.99 $468,181.95
Disclosure

SEC source: 0001962414-26-000002 · form4-03052026_060306.xml · nonDerivative · entry 1

Yoon Jun · CIK 0001962414 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,297,571

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 230 $85.04 $19,559.20
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 11

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 48,256

Underlying: Ordinary Shares · 690 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F5 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $85.02 to $85.06. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 6,498 $84.22 $547,261.56
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 10

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 48,486

Underlying: Ordinary Shares · 19,494 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F4 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $84.00 to $84.64. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 3,880 $83.35 $323,398.00
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 9

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 54,984

Underlying: Ordinary Shares · 11,640 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F3 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $83.00 to $83.84. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 5,477 $82.10 $449,661.70
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 8

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP LP

Disclosed balance after: 58,864

Underlying: Ordinary Shares · 16,431 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $82.00 to $82.37. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 20 $85.04 $1,700.80
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 7

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 4,103

Underlying: Ordinary Shares · 60 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F5 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $85.02 to $85.06. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 552 $84.22 $46,489.44
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 6

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 4,123

Underlying: Ordinary Shares · 1,656 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F4 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $84.00 to $84.64. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 330 $83.35 $27,505.50
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 5

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 4,675

Underlying: Ordinary Shares · 990 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F3 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $83.00 to $83.84. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
January 15, 2026 Filed Jan 20, 2026 14:22 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 465 $82.10 $38,176.50
Disclosure

SEC source: 0001193125-26-016062 · ownership.xml · derivative · entry 4

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 5,005

Underlying: Ordinary Shares · 1,395 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $82.00 to $82.37. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 15,535 $61.45 $954,625.75
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 13

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 0

Underlying: Ordinary Shares · 46,605 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F6 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $61.32 to $61.64. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 16,635 $61.05 $1,015,566.75
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 12

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 15,535

Underlying: Ordinary Shares · 49,905 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F5 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $60.32 to $61.31. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

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December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 5,589 $94.61 $528,775.29
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 11

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 32,170

Underlying: Ordinary Shares · 16,767 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F4 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $94.28 to $94.88. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 2,159 $94.00 $202,946.00
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 10

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 37,759

Underlying: Ordinary Shares · 6,477 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F3 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $93.27 to $94.26. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 8,337 $92.52 $771,339.24
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 9

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP

Disclosed balance after: 39,918

Underlying: Ordinary Shares · 25,011 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $92.29 to $92.93. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 1,320 $61.45 $81,114.00
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 8

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 1

Underlying: Ordinary Shares · 3,960 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F6 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $61.32 to $61.64. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 1,414 $61.05 $86,324.70
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 7

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 1,321

Underlying: Ordinary Shares · 4,242 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F5 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $60.32 to $61.31. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 475 $94.61 $44,939.75
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 6

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 2,735

Underlying: Ordinary Shares · 1,425 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F4 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $94.28 to $94.88. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 183 $94.00 $17,202.00
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 5

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 3,210

Underlying: Ordinary Shares · 549 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F3 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $93.27 to $94.26. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
December 08, 2025 Filed Dec 10, 2025 19:07 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 709 $92.52 $65,596.68
Disclosure

SEC source: 0001193125-25-313977 · ownership.xml · derivative · entry 4

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP

Disclosed balance after: 3,393

Underlying: Ordinary Shares · 2,127 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $92.29 to $92.93. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
November 20, 2025 Filed Mar 5, 2026 18:20 UTC
Hall AshleyChief Development Officer
GrantAmerican Depositary Shares · Derivative 237 $0.00 $0.00
Disclosure

SEC source: 0001801842-26-000002 · form4-03052026_060304.xml · derivative · entry 3

Hall Ashley · CIK 0001801842 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 462

Underlying: Ordinary Shares · 711 shares

Expires not disclosed

F3 · derivative.exercise_price: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F5 · kind: Voluntary reporting of the acquisition of 237 ADSs by the Reporting Person on November 20, 2025 pursuant to the Issuer's Employee Share Purchase Plan.

F3 · derivative.exercise_date: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F3 · derivative.expiration_date: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
November 20, 2025 Filed Mar 5, 2026 23:20 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
GrantAmerican Depositary Shares · Derivative 824 $0.00 $0.00
Disclosure

SEC source: 0001698149-26-000002 · form4-03052026_060301.xml · derivative · entry 3

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,824

Underlying: Ordinary Shares · 2,472 shares

Expires not disclosed

F4 · derivative.exercise_price: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F5 · kind: Voluntary reporting of the acquisition of 824 ADSs by the Reporting Person on November 20, 2025 pursuant to the Issuer's Employee Share Purchase Plan.

F4 · derivative.exercise_date: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F4 · derivative.expiration_date: Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.

F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

Read SEC document
September 18, 2025 Filed Sep 22, 2025 21:25 UTC
Coll Crespo BlasCHIEF MEDICAL OFFICER
Tax withholdingOrdinary Shares 8,106 $7.74 $62,767.19
Disclosure

SEC source: 0002037144-25-000003 · form4-09222025_090901.xml · nonDerivative · entry 1

Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 216,807

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
September 18, 2025 Filed Sep 22, 2025 21:25 UTC
Hall AshleyChief Development Officer
Tax withholdingOrdinary Shares 6,021 $7.74 $46,622.41
Disclosure

SEC source: 0001801842-25-000004 · form4-09222025_090903.xml · nonDerivative · entry 1

Hall Ashley · CIK 0001801842 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 112,317

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
July 30, 2025 Filed Aug 1, 2025 13:34 UTC
FMR LLC10% owner · See Remark 1
SaleAmerican Depositary Shares · Derivative 26,310 $17.87 $470,159.70
Disclosure

SEC source: 0000950170-25-101141 · ownership.xml · derivative · entry 3

FMR LLC · CIK 0000315066 · 10% owner · See Remark 1

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by persons and entities whose shares are subject to reporting by the undersigned

Disclosed balance after: 1,515,558

Underlying: Ordinary Shares · 78,930 shares

Expires not disclosed

F1 · derivative.exercise_price: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.exercise_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

F1 · derivative.expiration_date: Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 17:15 UTC
Coll Crespo BlasCHIEF MEDICAL OFFICER
Tax withholdingOrdinary Shares 1,434 $6.84 $9,803.68
Disclosure

SEC source: 0001415889-25-019354 · form4-07032025_050709.xml · nonDerivative · entry 3

Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 224,913

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 17:15 UTC
Coll Crespo BlasCHIEF MEDICAL OFFICER
GrantOrdinary Shares 7,992 $0.00 $0.00
Disclosure

SEC source: 0001415889-25-019354 · form4-07032025_050709.xml · nonDerivative · entry 2

Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,347

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F3 · kind: On March 15, 2024, the reporting person was granted performance-vesting restricted share units ("PSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer, which vest upon satisfaction of certain performance criteria. Certain of the performance criteria was determined to have been met effective July 1, 2025. The shares subject to the PSUs vest as follows: 50% of the shares vested on July 1, 2025 and the remainder will vest on January 1, 2027 subject to the reporting person's Continuous Service (as defined in the Structure Therapeutics Inc. 2023 Equity Incentive Plan) through such vesting date.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
Tax withholdingOrdinary Shares 16,050 $6.84 $109,727.43
Disclosure

SEC source: 0001415889-25-019350 · form4-07032025_050702.xml · nonDerivative · entry 3

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,194,830

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Stevens Raymond CDirector · CHIEF EXECUTIVE OFFICER
GrantOrdinary Shares 89,697 $0.00 $0.00
Disclosure

SEC source: 0001415889-25-019350 · form4-07032025_050702.xml · nonDerivative · entry 2

Stevens Raymond C · CIK 0001698149 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,210,880

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F3 · kind: On March 15, 2024, the reporting person was granted performance-vesting restricted share units ("PSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer, which vest upon satisfaction of certain performance criteria. Certain of the performance criteria was determined to have been met effective July 1, 2025. The shares subject to the PSUs vest as follows: 50% of the shares vested on July 1, 2025 and the remainder will vest on January 1, 2027 subject to the reporting person's Continuous Service (as defined in the Structure Therapeutics Inc. 2023 Equity Incentive Plan) through such vesting date.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Ma YingliCHIEF TECHNOLOGY OFFICER
GrantOrdinary Shares 24,459 $0.00 $0.00
Disclosure

SEC source: 0001415889-25-019353 · form4-07032025_050708.xml · nonDerivative · entry 2

Ma Yingli · CIK 0001963664 · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 123,174

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F3 · kind: On March 15, 2024, the reporting person was granted performance-vesting restricted share units ("PSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer, which vest upon satisfaction of certain performance criteria. Certain of the performance criteria was determined to have been met effective July 1, 2025. The shares subject to the PSUs vest as follows: 50% of the shares vested on July 1, 2025 and the remainder will vest on January 1, 2027 subject to the reporting person's Continuous Service (as defined in the Structure Therapeutics Inc. 2023 Equity Incentive Plan) through such vesting date.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Lin XichenCHIEF SCIENTIFIC OFFICER
GrantOrdinary Shares 57,078 $0.00 $0.00
Disclosure

SEC source: 0001415889-25-019352 · form4-07032025_050706.xml · nonDerivative · entry 2

Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 217,173

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F3 · kind: On March 15, 2024, the reporting person was granted performance-vesting restricted share units ("PSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer, which vest upon satisfaction of certain performance criteria. Certain of the performance criteria was determined to have been met effective July 1, 2025. The shares subject to the PSUs vest as follows: 50% of the shares vested on July 1, 2025 and the remainder will vest on January 1, 2027 subject to the reporting person's Continuous Service (as defined in the Structure Therapeutics Inc. 2023 Equity Incentive Plan) through such vesting date.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Yoon JunCHIEF FINANCIAL OFFICER
Tax withholdingOrdinary Shares 7,089 $6.84 $48,464.66
Disclosure

SEC source: 0001415889-25-019351 · form4-07032025_050704.xml · nonDerivative · entry 3

Yoon Jun · CIK 0001962414 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,319,876

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 21:15 UTC
Yoon JunCHIEF FINANCIAL OFFICER
GrantOrdinary Shares 39,606 $0.00 $0.00
Disclosure

SEC source: 0001415889-25-019351 · form4-07032025_050704.xml · nonDerivative · entry 2

Yoon Jun · CIK 0001962414 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,326,965

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F3 · kind: On March 15, 2024, the reporting person was granted performance-vesting restricted share units ("PSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer, which vest upon satisfaction of certain performance criteria. Certain of the performance criteria was determined to have been met effective July 1, 2025. The shares subject to the PSUs vest as follows: 50% of the shares vested on July 1, 2025 and the remainder will vest on January 1, 2027 subject to the reporting person's Continuous Service (as defined in the Structure Therapeutics Inc. 2023 Equity Incentive Plan) through such vesting date.

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July 01, 2025 Filed Aug 20, 2025 21:00 UTC
Ma YingliCHIEF TECHNOLOGY OFFICER
Tax withholdingOrdinary Shares 4,470 $6.84 $30,559.60
Disclosure

SEC source: 0001415889-25-022472 · form4-08202025_050803.xml · nonDerivative · entry 1

Ma Yingli · CIK 0001963664 · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 118,704

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

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July 01, 2025 Filed Aug 20, 2025 21:00 UTC
Lin XichenCHIEF SCIENTIFIC OFFICER
Tax withholdingOrdinary Shares 12,846 $6.84 $87,822.96
Disclosure

SEC source: 0001415889-25-022471 · form4-08202025_050801.xml · nonDerivative · entry 1

Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 204,327

F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer.

F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.