GOSS

SEC source: 0001728117-23-000086 · wf-form4_168780970194929.xml · nonDerivative · entry 1

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 197,574

F1 · shares: Represents a broker-assisted sale to satisfy the Reporting Person's tax withholding obligations in connection with the vesting of restricted stock units.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.285 to 1.29 per share. The price reported above reflects the weighted average sale price for the entire number of shares sold. Information on the exact number of shares sold at each sale price can be obtained from the Issuer upon request.

SEC source: 0001728117-23-000083 · wf-form4_168634170109729.xml · derivative · entry 1

Cox Russell J. · CIK 0001512984 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-06-07

F1 · shares: Award made pursuant to Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The entire number of shares subject to this option becomes fully vested and exercisable on the first to occur of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0001728117-23-000079 · wf-form4_168634161664139.xml · derivative · entry 1

Daniel Thomas O · CIK 0001538894 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-06-07

F1 · shares: Award made pursuant to Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The entire number of shares subject to this option becomes fully vested and exercisable on the first to occur of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0001728117-23-000078 · wf-form4_168634158506142.xml · derivative · entry 1

Burow Kristina · CIK 0001569248 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-06-07

F1 · shares: Award made pursuant to Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The entire number of shares subject to this option becomes fully vested and exercisable on the first to occur of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0001728117-23-000084 · wf-form4_168634174722045.xml · derivative · entry 1

GALA RENEE D · CIK 0001607737 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-06-07

F1 · shares: Award made pursuant to Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The entire number of shares subject to this option becomes fully vested and exercisable on the first to occur of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0001728117-23-000082 · wf-form4_168634167292261.xml · derivative · entry 1

Milligan Sandra · CIK 0001859810 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-06-07

F1 · shares: Award made pursuant to Non-Employee Director Compensation Program.

F2 · derivative.exercise_date: The entire number of shares subject to this option becomes fully vested and exercisable on the first to occur of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date.

SEC source: 0001728117-23-000052 · wf-form4_168366312804581.xml · derivative · entry 1

Hasnain Faheem · CIK 0001352620 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 750,000

Underlying: Common Stock · 750,000 shares

Expires 2033-05-04

F1 · derivative.exercise_date: The Option shall vest and become exercisable as follows: (i) with respect to 50% of the shares subject to the option, the Issuer's common stock achieving a 30-day average stock price at or above $5 per share within four years of the grant date; (ii) with respect to 25% of the shares subject to the option, the Issuer's common stock achieving a 30-day average stock price at or above $7.50 per share within four years of the grant date; and (iii) with respect to the remaining 25% of the shares subject to the option, the Issuer's common stock achieving a 30-day average stock price at or above $10 per share within four years of the grant date; in each case subject to the Reporting Person's continuous service to the Issuer on each such vesting date; provided in no event will any portion of the option vest prior to the first anniversary of the grant date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 8

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,667

Underlying: Common Stock · 126,667 shares

Expires 2032-01-05

F9 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F8 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 7

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2031-02-25

F9 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 60,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 6

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,667

Underlying: Common Stock · 47,667 shares

Expires 2030-02-14

F9 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F4 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 47,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 5

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2029-03-25

F9 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 70,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 4

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 190,000 shares

Expires 2032-01-05

F8 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 3

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 90,000 shares

Expires 2031-02-25

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 60,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 2

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 71,500 shares

Expires 2030-02-14

F4 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 47,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000055 · wf-form4_168366350375181.xml · derivative · entry 1

Christian Waage · CIK 0001553179 · EVP, Tech Ops and Admin

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 105,000 shares

Expires 2029-03-25

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 70,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 12

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,667

Underlying: Common Stock · 126,667 shares

Expires 2032-01-05

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F12 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F11 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 11

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,167

Underlying: Common Stock · 21,167 shares

Expires 2031-04-16

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F10 · price: On May 5, 2023, the Issuer canceled an option granted on April 16, 2021. In exchange for the canceled option, the reporting person received 21,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on April 16, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 10

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,834

Underlying: Common Stock · 18,834 shares

Expires 2031-02-25

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F8 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 18,834 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 9

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,784

Underlying: Common Stock · 22,784 shares

Expires 2030-02-14

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 22,784 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 8

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,167

Underlying: Common Stock · 9,167 shares

Expires 2029-12-23

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F4 · price: On May 5, 2023, the Issuer canceled an option granted on December 23, 2019. In exchange for the canceled option, the reporting person received 9,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on December 23, 2020 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 7

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,334

Underlying: Common Stock · 32,334 shares

Expires 2029-03-25

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 32,334 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 6

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 190,000 shares

Expires 2032-01-05

F12 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F11 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 5

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 31,750 shares

Expires 2031-04-16

F10 · price: On May 5, 2023, the Issuer canceled an option granted on April 16, 2021. In exchange for the canceled option, the reporting person received 21,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on April 16, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 4

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 28,250 shares

Expires 2031-02-25

F8 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 18,834 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 3

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 34,175 shares

Expires 2030-02-14

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 22,784 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 2

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,750 shares

Expires 2029-12-23

F4 · price: On May 5, 2023, the Issuer canceled an option granted on December 23, 2019. In exchange for the canceled option, the reporting person received 9,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on December 23, 2020 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000059 · wf-form4_168366387285335.xml · derivative · entry 1

Peterson Caryn · CIK 0001857256 · EVP, Regulatory Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 48,500 shares

Expires 2029-03-25

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 32,334 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 12

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,667

Underlying: Common Stock · 126,667 shares

Expires 2032-01-05

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F12 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F11 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 11

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2031-06-21

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F10 · price: On May 5, 2023, the Issuer canceled an option granted on June 21, 2021. In exchange for the canceled option, the reporting person received 20,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on June 21, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 10

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2031-02-25

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F8 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 40,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 9

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,784

Underlying: Common Stock · 22,784 shares

Expires 2030-02-14

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 22,784 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 8

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,167

Underlying: Common Stock · 9,167 shares

Expires 2029-12-23

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F4 · price: On May 5, 2023, the Issuer canceled an option granted on December 23, 2019. In exchange for the canceled option, the reporting person received 9,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on December 23, 2020 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 7

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2029-03-25

F13 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 30,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 6

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 190,000 shares

Expires 2032-01-05

F12 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 126,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F11 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 5

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2031-06-21

F10 · price: On May 5, 2023, the Issuer canceled an option granted on June 21, 2021. In exchange for the canceled option, the reporting person received 20,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on June 21, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 4

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 60,000 shares

Expires 2031-02-25

F8 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 40,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 3

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 34,175 shares

Expires 2030-02-14

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 22,784 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 2

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,750 shares

Expires 2029-12-23

F4 · price: On May 5, 2023, the Issuer canceled an option granted on December 23, 2019. In exchange for the canceled option, the reporting person received 9,167 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on December 23, 2020 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000057 · wf-form4_168366370450924.xml · derivative · entry 1

Aranda Richard · CIK 0001867872 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 45,000 shares

Expires 2029-03-25

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 30,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 10

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 176,667

Underlying: Common Stock · 176,667 shares

Expires 2032-01-05

F11 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F10 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 176,677 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 9

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2031-09-16

F11 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F8 · price: On May 5, 2023, the Issuer canceled an option granted on September 16, 2021. In exchange for the canceled option, the reporting person received 100,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on September 16, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Corporation on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 8

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2031-02-25

F11 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 60,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 7

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,667

Underlying: Common Stock · 47,667 shares

Expires 2030-02-14

F11 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F4 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 47,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 6

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,667

Underlying: Common Stock · 96,667 shares

Expires 2029-03-25

F11 · derivative.exercise_price: The exercise price of the option is $1.36 per share, representing the fair market value per share of the Issuer's common stock on the date of grant; provided that in the event the option is exercised prior to May 5, 2024, or the Reporting Person's employment terminates prior to May 5, 2024 other than due to death, disability or circumstances giving rise to severance under the Reporting Person's employment agreement, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted.

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 96,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 5

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 265,000 shares

Expires 2032-01-05

F10 · price: On May 5, 2023, the Issuer canceled an option granted on January 6, 2022. In exchange for the canceled option, the reporting person received 176,677 options to purchase common stock having a lower exercise price with the same vesting terms.

F9 · derivative.exercise_date: One-third of the total number of shares subject to the option vested on January 6, 2023 and 1/36th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 4

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 150,000 shares

Expires 2031-09-16

F8 · price: On May 5, 2023, the Issuer canceled an option granted on September 16, 2021. In exchange for the canceled option, the reporting person received 100,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F7 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on September 16, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Corporation on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 3

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 90,000 shares

Expires 2031-02-25

F6 · price: On May 5, 2023, the Issuer canceled an option granted on February 25, 2021. In exchange for the canceled option, the reporting person received 60,000 options to purchase common stock having a lower exercise price with the same vesting terms.

F5 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 25, 2022 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 2

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 71,500 shares

Expires 2030-02-14

F4 · price: On May 5, 2023, the Issuer canceled an option granted on February 14, 2020. In exchange for the canceled option, the reporting person received 47,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F3 · derivative.exercise_date: 25% of the total number of shares subject to the option vested on February 14, 2021 and 1/48th of the total number of shares subject to the option vest on the last day of each one-month period thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001728117-23-000053 · wf-form4_168366328309495.xml · derivative · entry 1

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 145,000 shares

Expires 2029-03-25

F2 · price: On May 5, 2023, the Issuer canceled an option granted on March 25, 2019. In exchange for the canceled option, the reporting person received 96,667 options to purchase common stock having a lower exercise price with the same vesting terms.

F1 · derivative.exercise_date: The shares subject to the option are fully vested.

SEC source: 0001728117-23-000032 · wf-form4_168072635273012.xml · nonDerivative · entry 1

Giraudo Bryan · CIK 0001740847 · COO/CFO

10b5-1 filing: No plan indicated

Ownership: Indirect · By family trust

Disclosed balance after: 125,990

F1 · price: This transaction was executed in multiple trades at prices ranging from $1.0198 to $1.02 per share. The price reported above reflects the weighted average sale price for the entire number of shares sold. Information on the exact number of shares sold at each sale price can be obtained from the Issuer upon request.