GH

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · derivative · entry 9

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,012

Underlying: COMMON STOCK · 18,562 shares

Expires 2026-07-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The stock option vests and becomes exercisable as to 25% of the options on July 18, 2017, thereafter vests in equal monthly installments over 36 months.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 8

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,875

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $78.42 to $79.21, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 7

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,775

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $77.18 to $78.09, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 6

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,075

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $76.10 to $77.03, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 5

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,375

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $75.08 to $76.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 4

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,832

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $74.05 to $74.98, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 3

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,037

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $73.01 to $73.90, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 2

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,037

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $3.63 pershare.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $71.91 to $72.70, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of theSecurities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006611 · wf-form4_155753786907798.xml · nonDerivative · entry 1

BERTOCCI DEREK A · CIK 0001206964 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,437

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001628280-19-006596 · wf-form4_155752508961628.xml · nonDerivative · entry 4

Wiley Michael J · CIK 0001753789 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 265,358

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-19-006596 · wf-form4_155752508961628.xml · nonDerivative · entry 3

Wiley Michael J · CIK 0001753789 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 265,458

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.00 to $67.99, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006596 · wf-form4_155752508961628.xml · nonDerivative · entry 2

Wiley Michael J · CIK 0001753789 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 265,958

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.92 to $66.85, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-006596 · wf-form4_155752508961628.xml · nonDerivative · entry 1

Wiley Michael J · CIK 0001753789 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 307,625

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.92 to $65.91, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-19-005842 · wf-form4_155692112718431.xml · derivative · entry 3

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,798

Underlying: COMMON STOCK · 2,690 shares

Expires 2027-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests and becomes exercisable in equal monthly installments over 48 months commencing on January 3, 2017.

SEC source: 0001628280-19-005842 · wf-form4_155692112718431.xml · nonDerivative · entry 2

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $4.18 per share.

SEC source: 0001628280-19-005842 · wf-form4_155692112718431.xml · nonDerivative · entry 1

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,690

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 13

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Isabella Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 0

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F12 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.58 to $65.56, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 12

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Isabella Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 6,158

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F11 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $63.58 to $64.53, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 11

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Genevieve Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 0

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F10 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.88 to $65.59, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 10

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Genevieve Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 3,750

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F9 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $63.87 to $64.86, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 9

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Camille Eltoukhy Irrevocable Trust

Disclosed balance after: 0

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F8 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.79 to $65.59, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 8

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Camille Eltoukhy Irrevocable Trust

Disclosed balance after: 4,529

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F7 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $63.80 to $64.73, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · derivative · entry 6

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,113

Underlying: COMMON STOCK · 2,306 shares

Expires 2028-08-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The stock option vests and becomes exercisable in equal monthly installments over 48 months commencing on August 22, 2018

F8 · derivative.expiration_date: The expiration date of August 21, 2028 reported in the Reporting Person's Form 3 filed on October 3, 2019 and Form 4 filed on April 17, 2019 was in error.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · derivative · entry 5

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,678

Underlying: COMMON STOCK · 1,536 shares

Expires 2027-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The stock option vests and becomes exercisable in equal monthly installments over 48 months commencing on April 1, 2017.

F6 · derivative.expiration_date: The expiration date of April 30, 2027 reported in the Reporting Person's Form 3 filed on October 3, 2019 and Form 4 filed on April 17, 2019 was in error.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · nonDerivative · entry 4

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,419

F2 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of one or more stock options at an exercise price of $4.18 or $8.80 per share.

F4 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.02 to $65.98, inclusive. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · nonDerivative · entry 3

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,619

F2 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of one or more stock options at an exercise price of $4.18 or $8.80 per share.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $63.95 to $64.75, inclusive. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · nonDerivative · entry 2

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 135,261

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001628280-19-005841 · wf-form4_155692094161070.xml · nonDerivative · entry 1

Lanman Richard B. · CIK 0001721003 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,955

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes shares acquired under the Issuer's 2018 Employee Stock Purchase Plan that were not included in the Reporting Person's last Form 4 filing.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 7

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Isabella Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 13,907

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 6

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Isabella Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 14,007

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F6 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.20 to $67.16, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 5

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Isabella Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 19,075

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.20 to $66.18, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 4

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Genevieve Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 13,907

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F5 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.21 to $67.16, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 3

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Genevieve Eltoukhy 2018 Irrevocable Trust

Disclosed balance after: 18,906

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.19 to $66.18, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 2

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Camille Eltoukhy Irrevocable Trust

Disclosed balance after: 13,907

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.20 to $67.17, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-005705 · wf-form4_155683202270643.xml · nonDerivative · entry 1

Eltoukhy Helmy · CIK 0001752968 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Camille Eltoukhy Irrevocable Trust

Disclosed balance after: 19,509

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.20 to $66.18, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004973 · wf-form4_155657717448512.xml · derivative · entry 3

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,140

Underlying: COMMON STOCK · 538 shares

Expires 2027-11-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vests and becomes exercisable in equal monthly installments over 48 months commencing on October 25, 2017.

SEC source: 0001628280-19-004973 · wf-form4_155657717448512.xml · nonDerivative · entry 2

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The shares sold were acquired contemporaneously upon the cashless exercise of stock options at an exercise price of $4.18 per share.

SEC source: 0001628280-19-004973 · wf-form4_155657717448512.xml · nonDerivative · entry 1

CLARK IAN T · CIK 0001336504 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 538

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · derivative · entry 29

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,132,000

Underlying: COMMON STOCK · 7,454 shares

Expires 2027-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F26 · derivative.exercise_date: The stock option vests and becomes exercisable in equal monthly installments over 48 months commencing on April 23, 2017.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 26

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,960

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F25 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.90 to $67.17, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 25

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,869

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F24 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.87 to $66.86, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 24

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,884

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F23 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.86 to $65.85, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 23

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,892

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · shares: The shares were acquired and then sold contemporaneously upon the cashless exercise of stock option at an exercise price of $4.18 per share.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 22

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Sana Talasaz 2018 Irrevocable Trust

Disclosed balance after: 13,333

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 21

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Sana Talasaz 2018 Irrevocable Trust

Disclosed balance after: 13,433

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F22 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.96 to $66.9, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 20

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Sana Talasaz 2018 Irrevocable Trust

Disclosed balance after: 16,302

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F21 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.96 to $65.94, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 19

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Samar Talasaz 2018 Irrevocable Trust

Disclosed balance after: 13,333

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F20 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.86 to $67.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 18

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Samar Talasaz 2018 Irrevocable Trust

Disclosed balance after: 13,733

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F19 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $65.86 to $66.85, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 17

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Samar Talasaz 2018 Irrevocable Trust

Disclosed balance after: 16,513

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F18 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $64.81 to $65.73, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001628280-19-004762 · wf-form4_155623750501525.xml · nonDerivative · entry 16

Talasaz AmirAli · CIK 0001753159 · Director · Chairman, President and COO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 3,745,120

F1 · shares: These shares were sold under a pre-arranged sales plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F17 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $66.78 to $67.29, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.