DXCM

SEC source: 0001093557-18-000205 · edgardoc.xml · nonDerivative · entry 2

Balo Andrew K · CIK 0001323190 · EVP, Reg. Strategy, Clinical

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,105

F1 · shares: On June 14, 2018, Mr. Balo adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Balo. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F4 · price: This transaction was executed in multiple trades at prices ranging from $145.00 to $145.70. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issurer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 59,217 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 14,381 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000205 · edgardoc.xml · nonDerivative · entry 1

Balo Andrew K · CIK 0001323190 · EVP, Reg. Strategy, Clinical

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,505

F1 · shares: On June 14, 2018, Mr. Balo adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Balo. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $144.00 to $144.82. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 59,217 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 14,381 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000203 · edgardoc.xml · derivative · entry 4

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2018-10-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-18-000203 · edgardoc.xml · nonDerivative · entry 1

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,284

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Included in this number are 46,994 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 11,567 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,334 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0000899243-18-024485 · doc4.xml · nonDerivative · entry 4

Blackford Quentin S. · CIK 0001612451 · EVP, CFO, PFO & PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,131

F1 · shares: On August 7, 2018, Mr. Blackford adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Blackford. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F6 · price: This transaction was executed in multiple trades at prices ranging from $147.75 to $148.44. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 85,271 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021 and 46,769 of which were granted on September 7, 2017 and shall vest through September 7, 2021.

SEC source: 0000899243-18-024485 · doc4.xml · nonDerivative · entry 3

Blackford Quentin S. · CIK 0001612451 · EVP, CFO, PFO & PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,811

F1 · shares: On August 7, 2018, Mr. Blackford adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Blackford. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F5 · price: This transaction was executed in multiple trades at prices ranging from $146.75 to $147.74. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 85,271 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021 and 46,769 of which were granted on September 7, 2017 and shall vest through September 7, 2021.

SEC source: 0000899243-18-024485 · doc4.xml · nonDerivative · entry 2

Blackford Quentin S. · CIK 0001612451 · EVP, CFO, PFO & PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,271

F1 · shares: On August 7, 2018, Mr. Blackford adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Blackford. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F4 · price: This transaction was executed in multiple trades at prices ranging from $145.68 to $146.58. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 85,271 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021 and 46,769 of which were granted on September 7, 2017 and shall vest through September 7, 2021.

SEC source: 0000899243-18-024485 · doc4.xml · nonDerivative · entry 1

Blackford Quentin S. · CIK 0001612451 · EVP, CFO, PFO & PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,471

F1 · shares: On August 7, 2018, Mr. Blackford adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Blackford. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $144.54 to $145.50. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · balance_after: Included in this number are 85,271 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021 and 46,769 of which were granted on September 7, 2017 and shall vest through September 7, 2021.

SEC source: 0001093557-18-000201 · edgardoc.xml · nonDerivative · entry 5

MOY JEFFREY · CIK 0001446422 · SVP, Operations

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 16,711

F5 · shares: On May 29, 2018, Mr. Moy adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Moy. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F4 · ownership.nature: Shares are held by the Moy Family Trust U/A/D 12/09/2013, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000201 · edgardoc.xml · nonDerivative · entry 4

MOY JEFFREY · CIK 0001446422 · SVP, Operations

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 22,447

F3 · shares: Shares were transferred from direct ownership to ownership under the Moy Family Trust upon vesting of previously awarded restricted stock units.

F4 · ownership.nature: Shares are held by the Moy Family Trust U/A/D 12/09/2013, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000201 · edgardoc.xml · nonDerivative · entry 3

MOY JEFFREY · CIK 0001446422 · SVP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,534

F3 · shares: Shares were transferred from direct ownership to ownership under the Moy Family Trust upon vesting of previously awarded restricted stock units.

F2 · balance_after: Included in this number are 46,534 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 10,941 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,500 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000201 · edgardoc.xml · nonDerivative · entry 2

MOY JEFFREY · CIK 0001446422 · SVP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,920

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 46,534 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 10,941 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,500 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000201 · edgardoc.xml · nonDerivative · entry 1

MOY JEFFREY · CIK 0001446422 · SVP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,682

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 46,534 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 10,941 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,500 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000200 · edgardoc.xml · nonDerivative · entry 3

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,804

F3 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 58,591 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000200 · edgardoc.xml · nonDerivative · entry 2

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,984

F3 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 58,591 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000199 · edgardoc.xml · nonDerivative · entry 2

Balo Andrew K · CIK 0001323190 · EVP, Reg. Strategy, Clinical

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,105

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 59,217 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 14,381 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000199 · edgardoc.xml · nonDerivative · entry 1

Balo Andrew K · CIK 0001323190 · EVP, Reg. Strategy, Clinical

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,285

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 59,217 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 14,381 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000198 · edgardoc.xml · nonDerivative · entry 2

Pacelli Steven Robert · CIK 0001359098 · EVP, Strategy & Corp. Dev.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,974

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 58,591 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020, and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000198 · edgardoc.xml · nonDerivative · entry 1

Pacelli Steven Robert · CIK 0001359098 · EVP, Strategy & Corp. Dev.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,277

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 58,591 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020, and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000197 · edgardoc.xml · nonDerivative · entry 3

Murphy Patrick Michael · CIK 0001692785 · VP, Legal Aff & Chf Compl Ofcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,308

F3 · shares: On June 15, 2018, Mr. Murphy adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Murphy. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F2 · balance_after: Included in this number are 24,998 unvested restricted stock units, 16,817 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 5,681 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 2,500 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000197 · edgardoc.xml · nonDerivative · entry 2

Murphy Patrick Michael · CIK 0001692785 · VP, Legal Aff & Chf Compl Ofcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,708

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 24,998 unvested restricted stock units, 16,817 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 5,681 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 2,500 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000197 · edgardoc.xml · nonDerivative · entry 1

Murphy Patrick Michael · CIK 0001692785 · VP, Legal Aff & Chf Compl Ofcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,729

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 24,998 unvested restricted stock units, 16,817 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 5,681 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 2,500 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000196 · edgardoc.xml · nonDerivative · entry 2

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,284

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 46,994 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 11,567 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,334 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000196 · edgardoc.xml · nonDerivative · entry 1

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,962

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 46,994 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 11,567 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 5,334 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000195 · edgardoc.xml · nonDerivative · entry 1

ACE HEATHER S · CIK 0001610762 · SVP Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,339

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 54,784 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 10,941 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 13,750 of which were granted on August 22, 2016 and shall vest through August 22, 2020.

SEC source: 0001093557-18-000194 · edgardoc.xml · nonDerivative · entry 1

Abbey Donald · CIK 0001534342 · EVP, Quality & Regulatory Afrs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,639

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 70,590 restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 18,333 of which were granted on May 31, 2016 and shall vest through May 31, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · derivative · entry 7

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,484

Underlying: Common Stock · 11,161 shares

Expires 2019-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 6

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 320,837

F6 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 5

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 327,639

F6 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 4

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 335,171

F2 · shares: On May 10, 2018, Mr. Sayer adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Sayer. The exercise and sale of shares set forth above were pursuant to the 10b5-1 Plan.

F5 · price: This transaction was executed in multiple trades at prices ranging from $143.78 to $144.28. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 3

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 338,932

F2 · shares: On May 10, 2018, Mr. Sayer adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Sayer. The exercise and sale of shares set forth above were pursuant to the 10b5-1 Plan.

F4 · price: This transaction was executed in multiple trades at prices ranging from $142.78 to $143.77. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 2

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 344,832

F2 · shares: On May 10, 2018, Mr. Sayer adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Sayer. The exercise and sale of shares set forth above were pursuant to the 10b5-1 Plan.

F3 · price: This transaction was executed in multiple trades at prices ranging from $141.77 to $142.72. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000192 · edgardoc.xml · nonDerivative · entry 1

SAYER KEVIN R · CIK 0001286858 · Director · President, CEO & Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 346,332

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Included in this number are 136,185 unvested restricted stock units, 80,545 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 40,640 of which were granted on March 8, 2017 and shall vest through March 8, 2020, 15,000 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000193 · edgardoc.xml · nonDerivative · entry 1

Blackford Quentin S. · CIK 0001612451 · EVP, CFO, PFO & PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,571

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · balance_after: Included in this number are 85,271 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021 and 46,769 of which were granted on September 7, 2017 and shall vest through September 7, 2021.

SEC source: 0001093557-18-000200 · edgardoc.xml · nonDerivative · entry 4

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 20,830

F1 · shares: Shares were transferred from direct ownership to ownership under the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.

F4 · ownership.nature: Shares are held by the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000200 · edgardoc.xml · nonDerivative · entry 1

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,287

F1 · shares: Shares were transferred from direct ownership to ownership under the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.

F2 · balance_after: Included in this number are 58,591 unvested restricted stock units, 38,502 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 13,755 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 6,334 of which were granted on March 8, 2016 and shall vest through March 8, 2019.

SEC source: 0001093557-18-000181 · edgardoc.xml · nonDerivative · entry 1

ALTMAN STEVEN R · CIK 0001191307 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Foundation

Disclosed balance after: 0

F1 · price: This transaction was executed in multiple trades at prices ranging from $136.47 to $136.56. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F2 · ownership.nature: Shares held by The Lisa and Steve Altman Family Foundation with respect to which the reporting person is an authorized agent.

SEC source: 0001093557-18-000179 · edgardoc.xml · nonDerivative · entry 1

FOLETTA MARK G · CIK 0001236389 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 17,095

F1 · balance_after: Shares are held by the Mark G. and Mary E. Foletta, TTEE's for the Foletta Family Trust DTD 1/30/15, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000178 · edgardoc.xml · derivative · entry 8

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 10,000 shares

Expires 2018-10-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-18-000178 · edgardoc.xml · derivative · entry 7

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,577 shares

Expires 2018-12-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-18-000178 · edgardoc.xml · nonDerivative · entry 4

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,878

F1 · price: This transaction was executed in multiple trades at prices ranging from $138.19 to $138.65. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Included in this number are 56,182 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 15,422 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 10,667 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000178 · edgardoc.xml · nonDerivative · entry 3

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,878

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-18-000178 · edgardoc.xml · nonDerivative · entry 2

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,878

F1 · price: This transaction was executed in multiple trades at prices ranging from $138.19 to $138.65. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F2 · balance_after: Included in this number are 56,182 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 15,422 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 10,667 of which were granted on March 8, 2016 shall vest through March 8, 2019.

SEC source: 0001093557-18-000178 · edgardoc.xml · nonDerivative · entry 1

Leach Jacob Steven · CIK 0001700255 · SVP, Research & Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,455

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001093557-19-000031 · edgardoc.xml · nonDerivative · entry 4

ALTMAN STEVEN R · CIK 0001191307 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 57,855

F2 · shares: Shares were transferred from the Steven R. and Lisa J. Altman, TTEE's Altman Family Trust DTD 8/21/92, to ownership under The Lisa and Steve Altman Family Foundation with respect to which the reporting person is an authorized agent.

SEC source: 0001093557-19-000031 · edgardoc.xml · nonDerivative · entry 2

ALTMAN STEVEN R · CIK 0001191307 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Foundation

Disclosed balance after: 5,000

F2 · shares: Shares were transferred from the Steven R. and Lisa J. Altman, TTEE's Altman Family Trust DTD 8/21/92, to ownership under The Lisa and Steve Altman Family Foundation with respect to which the reporting person is an authorized agent.

SEC source: 0001093557-18-000175 · edgardoc.xml · nonDerivative · entry 1

ACE HEATHER S · CIK 0001610762 · SVP Human Resources

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,171

F1 · shares: Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of RSUs. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Included in this number are 58,431 unvested restricted stock units, 30,093 of which were granted on March 8, 2018 and shall vest through March 8, 2021, 14,588 of which were granted on March 8, 2017 and shall vest through March 8, 2020 and 13,750 of which were granted on August 22, 2016 and shall vest through August 22, 2020.

SEC source: 0001093557-18-000174 · edgardoc.xml · nonDerivative · entry 3

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 0

F1 · shares: On May 16, 2017 Mr. Doubleday adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Doubleday. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F3 · ownership.nature: Shares are held by the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000174 · edgardoc.xml · nonDerivative · entry 2

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 100

F1 · shares: On May 16, 2017 Mr. Doubleday adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Doubleday. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F4 · price: This transaction was executed in multiple trades at prices ranging from $140.27 to $141.08. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · ownership.nature: Shares are held by the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.

SEC source: 0001093557-18-000174 · edgardoc.xml · nonDerivative · entry 1

DOUBLEDAY RICHARD · CIK 0001466545 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 650

F1 · shares: On May 16, 2017 Mr. Doubleday adopted a 10b5-1 Plan. This 10b5-1 Plan allows the orderly disposition of shares owned by Mr. Doubleday. The shares set forth above were sold pursuant to the 10b5-1 Plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $139.24 to $140.24. The price above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transactions were effected.

F3 · ownership.nature: Shares are held by the Doubleday Living Trust U/A/D 5/26/2015, with respect to which the reporting person is a trustee.