DTIL

SEC source: 0000950170-24-072052 · ownership.xml · derivative · entry 3

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 301 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F5 · derivative.exercise_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

F5 · derivative.expiration_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

SEC source: 0000950170-24-072052 · ownership.xml · nonDerivative · entry 1

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,814

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on June 7, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

SEC source: 0000950170-24-072050 · ownership.xml · derivative · entry 2

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 454 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · derivative.exercise_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

F3 · derivative.expiration_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

SEC source: 0000950170-24-072050 · ownership.xml · nonDerivative · entry 1

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,468

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on June 7, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

SEC source: 0000950170-24-072049 · ownership.xml · derivative · entry 4

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 163 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F5 · derivative.exercise_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

F5 · derivative.expiration_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on June 7, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates. The RSUs vested in full on June 7, 2024.

SEC source: 0000950170-24-072049 · ownership.xml · nonDerivative · entry 1

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,609

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on June 7, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

SEC source: 0000950170-24-069940 · ownership.xml · derivative · entry 1

Frankel Stanley · CIK 0001855726 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-069938 · ownership.xml · derivative · entry 1

Germano Geno J · CIK 0001424383 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-069942 · ownership.xml · derivative · entry 1

Brown Melinda · CIK 0001682988 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-069941 · ownership.xml · derivative · entry 1

Buehler Kevin · CIK 0001792722 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-069936 · ownership.xml · derivative · entry 1

Pire Shari Lisa · CIK 0001892150 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-069934 · ownership.xml · derivative · entry 1

Wadsworth Samuel C. · CIK 0001653056 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock or, at the Issuer's option, an amount of cash equal to the fair market value of such shares.

F2 · derivative.exercise_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

F2 · derivative.expiration_date: The RSUs vest on the earlier to occur of (i) June 4, 2025 and (ii) the day immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in either case, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date.

SEC source: 0000950170-24-056138 · ownership.xml · nonDerivative · entry 1

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,513

F1 · shares: Represents shares purchased through a definitive subscription agreement, pursuant to which the Issuer agreed to issue and sell shares of its common stock in a non-brokered private placement to certain members of its management.

SEC source: 0000950170-24-056141 · ownership.xml · nonDerivative · entry 1

Amoroso Michael · CIK 0001830874 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,106

F1 · shares: Represents shares purchased through a definitive subscription agreement, pursuant to which the Issuer agreed to issue and sell shares of its common stock in a non-brokered private placement to certain members of its management.

SEC source: 0000950170-24-056140 · ownership.xml · nonDerivative · entry 1

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,014

F1 · shares: Represents shares purchased through a definitive subscription agreement, pursuant to which the Issuer agreed to issue and sell shares of its common stock in a non-brokered private placement to certain members of its management.

SEC source: 0000950170-24-056139 · ownership.xml · nonDerivative · entry 1

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,446

F1 · shares: Represents shares purchased through a definitive subscription agreement, pursuant to which the Issuer agreed to issue and sell shares of its common stock in a non-brokered private placement to certain members of its management.

SEC source: 0000950170-24-054579 · ownership.xml · derivative · entry 2

Frankel Stanley · CIK 0001855726 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

SEC source: 0000950170-24-054579 · ownership.xml · nonDerivative · entry 1

Frankel Stanley · CIK 0001855726 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,252

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-054581 · ownership.xml · derivative · entry 2

Germano Geno J · CIK 0001424383 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

SEC source: 0000950170-24-054581 · ownership.xml · nonDerivative · entry 1

Germano Geno J · CIK 0001424383 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-054587 · ownership.xml · derivative · entry 2

Pire Shari Lisa · CIK 0001892150 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

SEC source: 0000950170-24-054587 · ownership.xml · nonDerivative · entry 1

Pire Shari Lisa · CIK 0001892150 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-054586 · ownership.xml · derivative · entry 2

Buehler Kevin · CIK 0001792722 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

SEC source: 0000950170-24-054586 · ownership.xml · nonDerivative · entry 1

Buehler Kevin · CIK 0001792722 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,392

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-054584 · ownership.xml · derivative · entry 2

Wadsworth Samuel C. · CIK 0001653056 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024.

SEC source: 0000950170-24-054584 · ownership.xml · nonDerivative · entry 1

Wadsworth Samuel C. · CIK 0001653056 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-054576 · ownership.xml · derivative · entry 2

Brown Melinda · CIK 0001682988 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,202 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024

F4 · derivative.expiration_date: On May 4, 2023 the Reporting Person was granted RSUs. The RSUs vested in full on May 4, 2024

SEC source: 0000950170-24-054576 · ownership.xml · nonDerivative · entry 1

Brown Melinda · CIK 0001682988 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the vesting and settlement of Restricted Stock Units ("RSUs") on May 4, 2024.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-053115 · ownership.xml · nonDerivative · entry 2

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,680

F4 · kind: The sales were effected pursuant to a Rule 10b5-1 plan adopted on July 14, 2023. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.11 to $10.53. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote.

SEC source: 0000950170-24-053114 · ownership.xml · nonDerivative · entry 3

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,613

F4 · kind: The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.11 to $10.53. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote.

SEC source: 0000950170-24-053113 · ownership.xml · nonDerivative · entry 2

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,488

F3 · kind: The sales were effected pursuant to a Rule 10b5-1 plan adopted on March 24, 2022. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.11 to $10.53. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote.

SEC source: 0000950170-24-053112 · ownership.xml · nonDerivative · entry 2

Amoroso Michael · CIK 0001830874 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,772

F4 · kind: The sales were effected pursuant to a Rule 10b5-1 plan adopted on March 24, 2022. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.11 to $10.53. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote.

SEC source: 0000950170-24-053115 · ownership.xml · derivative · entry 3

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 919

Underlying: Common Stock · 918 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F6 · derivative.exercise_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6 · derivative.expiration_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053115 · ownership.xml · nonDerivative · entry 1

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,952

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the partial vesting of Restricted Stock Units ("RSUs") on March 3, 2024, and subsequent settlement of such vested RSUs on May 1, 2024.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-053116 · ownership.xml · derivative · entry 3

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,702

Underlying: Common Stock · 1,702 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F4 · derivative.exercise_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F4 · derivative.expiration_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053116 · ownership.xml · nonDerivative · entry 2

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,680

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · shares: Represents the partial vesting of Restricted Stock Units ("RSUs") on March 3, 2024, and subsequent settlement of such vested RSUs on May 1, 2024.

F3 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

SEC source: 0000950170-24-053114 · ownership.xml · derivative · entry 5

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 519

Underlying: Common Stock · 519 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F6 · derivative.exercise_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6 · derivative.expiration_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053114 · ownership.xml · nonDerivative · entry 2

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,767

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the partial vesting of Restricted Stock Units ("RSUs") on March 3, 2024, and subsequent settlement of such vested RSUs on May 1, 2024.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-053113 · ownership.xml · derivative · entry 3

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 981

Underlying: Common Stock · 982 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F5 · derivative.exercise_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F5 · derivative.expiration_date: On March 3, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 3, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053113 · ownership.xml · nonDerivative · entry 1

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,778

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the partial vesting of Restricted Stock Units ("RSUs") on March 3, 2024, and subsequent settlement of such vested RSUs on May 1, 2024.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

SEC source: 0000950170-24-053112 · ownership.xml · derivative · entry 3

Amoroso Michael · CIK 0001830874 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,417

Underlying: Common Stock · 3,417 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F6 · derivative.exercise_date: On March 21, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 21, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6 · derivative.expiration_date: On March 21, 2022 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on March 21, 2023, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053112 · ownership.xml · nonDerivative · entry 1

Amoroso Michael · CIK 0001830874 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,298

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the partial vesting of Restricted Stock Units ("RSUs") on March 21, 2024, and subsequent settlement of such vested RSUs on May 1, 2024.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-050769 · ownership.xml · nonDerivative · entry 2

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,796

F4 · kind: The sales were effected pursuant to a Rule 10b5-1 plan adopted on March 24, 2022. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.85 to $10.14. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares acquired at each separate price within the range set forth in this footnote.

SEC source: 0000950170-24-050769 · ownership.xml · derivative · entry 3

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 868 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F6 · derivative.exercise_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on April 26, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6 · derivative.expiration_date: On June 7, 2021 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on April 26, 2022, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-050769 · ownership.xml · nonDerivative · entry 1

List Alan · CIK 0001858530 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,034

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents the partial vesting and settlement of Restricted Stock Units ("RSUs") on April 26, 2024.

F2 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F3 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.

SEC source: 0000950170-24-046597 · ownership.xml · derivative · entry 1

Scimeca Dario · CIK 0001779581 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,277

Underlying: Common Stock · 25,277 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F2 · derivative.exercise_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F2 · derivative.expiration_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-046599 · ownership.xml · derivative · entry 1

SMITH J. JEFFERSON · CIK 0001770169 · Chief Research Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,343

Underlying: Common Stock · 31,343 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F2 · derivative.exercise_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F2 · derivative.expiration_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-046598 · ownership.xml · derivative · entry 1

Amoroso Michael · CIK 0001830874 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,217

Underlying: Common Stock · 111,217 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F2 · derivative.exercise_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F2 · derivative.expiration_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-046596 · ownership.xml · derivative · entry 1

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,705

Underlying: Common Stock · 41,705 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.

F2 · derivative.exercise_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F2 · derivative.expiration_date: Award vests in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0000950170-24-053116 · ownership.xml · nonDerivative · entry 1

Kelly John Alexander · CIK 0001590030 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,978

F1 · balance_after: On February 13, 2024, the Issuer effected a 1-for-30 reverse stock split. The amounts of securities herein have been adjusted to reflect the reverse stock split.