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Nasdaq · USD

CSTL

CASTLE BIOSCIENCES INC

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359
SEC CIK
0001447362
Parsed reports
578

Last 12 months

Inside the activity.

0 purchase rows · 214 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025014
Dec 2025010
Jan 202603
Feb 202603
Mar 2026026
Apr 2026014
May 2026028
Jun 2026015
Jul 2026036
Aug 2026044
Sep 2026015
Oct 202606

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 31, 2020 Filed Sep 2, 2020 21:45 UTC SaleCommon Stock 8,228 $45.84 $377,171.52
Disclosure

SEC source: 0001447362-20-000199 · wf-form4_159908308910869.xml · nonDerivative · entry 1

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,113,382

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $45.96, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 28, 2020 Filed Aug 31, 2020 20:08 UTC SaleCommon Stock 2,500 $46.48 $116,200.00
Disclosure

SEC source: 0001447362-20-000197 · wf-form4_159890448085845.xml · nonDerivative · entry 1

Aspinall Mara G. · CIK 0001623049 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,348

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 1, 2020.

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August 28, 2020 Filed Aug 31, 2020 20:05 UTC SaleCommon Stock 3,609 $46.15 $166,555.35
Disclosure

SEC source: 0001447362-20-000195 · wf-form4_159890429738649.xml · nonDerivative · entry 4

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,121,610

F8 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 LP on March 13, 2020.

F9 · price: This transaction was executed in multiple trades at prices ranging from $46.00 to $46.46, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 28, 2020 Filed Aug 31, 2020 20:05 UTC SaleCommon Stock 3,605 $46.16 $166,406.80
Disclosure

SEC source: 0001447362-20-000195 · wf-form4_159890429738649.xml · nonDerivative · entry 3

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,125,219

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 QP LP on March 13, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $46.00 to $46.47, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 28, 2020 Filed Aug 31, 2020 20:05 UTC SaleCommon Stock 48,487 $46.06 $2,233,311.22
Disclosure

SEC source: 0001447362-20-000195 · wf-form4_159890429738649.xml · nonDerivative · entry 2

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,128,824

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $46.47, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 27, 2020 Filed Aug 31, 2020 20:05 UTC SaleCommon Stock 16,239 $45.89 $745,207.71
Disclosure

SEC source: 0001447362-20-000195 · wf-form4_159890429738649.xml · nonDerivative · entry 1

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,177,311

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $46.01, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 26, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 100 $46.00 $4,600.00
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 6

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,193,550

F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 LP on March 13, 2020.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 26, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 70 $46.00 $3,220.00
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 5

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,193,650

F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 QP LP on March 13, 2020.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 26, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 4,879 $45.85 $223,692.39
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 4

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,193,720

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $45.800 to $46.100, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 25, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 200 $46.05 $9,209.00
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 3

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,198,599

F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 LP on March 13, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $46.000 to $46.090, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 25, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 200 $46.05 $9,209.00
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 2

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,198,799

F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 QP LP on March 13, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $46.000 to $46.090, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 25, 2020 Filed Aug 27, 2020 20:04 UTC SaleCommon Stock 17,148 $45.90 $787,007.46
Disclosure

SEC source: 0001447362-20-000193 · wf-form4_159855867654281.xml · nonDerivative · entry 1

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,198,999

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $45.800 to $46.125, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 24, 2020 Filed Aug 25, 2020 20:11 UTC SaleCommon Stock 8,877 $45.90 $407,454.30
Disclosure

SEC source: 0001447362-20-000191 · wf-form4_159838628445835.xml · nonDerivative · entry 2

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,216,147

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $46.01, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 21, 2020 Filed Aug 25, 2020 20:11 UTC SaleCommon Stock 6,017 $45.85 $275,879.45
Disclosure

SEC source: 0001447362-20-000191 · wf-form4_159838628445835.xml · nonDerivative · entry 1

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,225,024

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $45.95, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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August 20, 2020 Filed Aug 21, 2020 20:06 UTC SaleCommon Stock 300 $46.06 $13,818.00
Disclosure

SEC source: 0001447362-20-000188 · wf-form4_159804038445523.xml · nonDerivative · entry 4

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,231,041

F7 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 LP on March 13, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $46.03 to $46.08, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 20, 2020 Filed Aug 21, 2020 20:06 UTC SaleCommon Stock 100 $46.03 $4,603.00
Disclosure

SEC source: 0001447362-20-000188 · wf-form4_159804038445523.xml · nonDerivative · entry 3

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,231,341

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by MGC 2018 QP LP on March 13, 2020.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 20, 2020 Filed Aug 21, 2020 20:06 UTC SaleCommon Stock 8,395 $45.84 $384,826.80
Disclosure

SEC source: 0001447362-20-000188 · wf-form4_159804038445523.xml · nonDerivative · entry 2

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,231,441

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $46.03, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 19, 2020 Filed Aug 20, 2020 20:06 UTC SaleCommon Stock 750 $45.78 $34,335.00
Disclosure

SEC source: 0001447362-20-000183 · wf-form4_159795400535510.xml · nonDerivative · entry 4

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 848,578

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $45.73 to $45.86, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 19, 2020 Filed Aug 20, 2020 20:06 UTC SaleCommon Stock 1,800 $45.26 $81,468.00
Disclosure

SEC source: 0001447362-20-000183 · wf-form4_159795400535510.xml · nonDerivative · entry 3

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 849,328

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $44.73 to $45.71, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 19, 2020 Filed Aug 20, 2020 20:06 UTC SaleCommon Stock 1,200 $43.90 $52,680.00
Disclosure

SEC source: 0001447362-20-000183 · wf-form4_159795400535510.xml · nonDerivative · entry 2

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 851,128

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $43.39 to $44.24, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 19, 2020 Filed Aug 21, 2020 20:05 UTC SaleCommon Stock 75,000 $44.78 $3,358,500.00
Disclosure

SEC source: 0001447362-20-000187 · wf-form4_159804034038113.xml · nonDerivative · entry 1

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 1,058,577

F1 · kind: The transaction on this Form 4 was made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on May 22, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $44.16 to $45.13, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
August 19, 2020 Filed Aug 21, 2020 20:07 UTC
Spiess Bernhard E.Chief Business Officer
SaleCommon Stock 20,000 $45.00 $900,000.00
Disclosure

SEC source: 0001447362-20-000189 · wf-form4_159804042475133.xml · nonDerivative · entry 1

Spiess Bernhard E. · CIK 0001782994 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,626

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on August 18, 2020.

Read SEC document
August 19, 2020 Filed Aug 21, 2020 20:06 UTC SaleCommon Stock 8,574 $45.83 $392,946.42
Disclosure

SEC source: 0001447362-20-000188 · wf-form4_159804038445523.xml · nonDerivative · entry 1

Cook Joseph C. III · CIK 0001783205 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,239,836

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by MGC Venture Partners 2013, L.P. ("MGC 2013 LP") on March 13, 2020, as amended on June 1, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $45.80 to $45.90, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by MGC 2013 LP, MGC Venture Partners 2018, L.P. ("MGC 2018 LP"), MGC Venture Partners QP 2018, L.P. ("MGC 2018 QP LP") and MGC Venture Partners 2013 GP, LLC ("MGC 2013 GP"). MGC 2013 GP is the general partner of MGC 2013 LP. MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP LP.

F4 · ownership.nature: The Reporting Person is a managing director of MGC 2013 GP and a managing partner of MGC 2018 GP, and shares voting and investment power over the shares held by MGC 2013 LP, MGC 2018 LP, MGC 2018 QP LP and MGC 2013 GP. The Reporting Person disclaims beneficial ownership of the shares held by MGC 2013 GP, MGC 2018 GP, MGC 2013 LP, MGC 2018 LP and MGC 2018 QP LP as reported herein, except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 18, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,000 $43.20 $43,200.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 8

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,530,848

F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F9 · price: This transaction was executed in multiple trades at prices ranging from $42.97 to $43.45, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 18, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 100 $43.67 $4,367.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 7

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,531,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

Read SEC document
August 18, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 9,900 $43.14 $427,086.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 6

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,531,948

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $42.65 to $43.58, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 18, 2020 Filed Aug 20, 2020 20:06 UTC SaleCommon Stock 3,750 $43.18 $161,925.00
Disclosure

SEC source: 0001447362-20-000183 · wf-form4_159795400535510.xml · nonDerivative · entry 1

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 852,328

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $42.78 to $43.62, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 17, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 400 $43.60 $17,440.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 5

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,541,848

F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $43.47 to $43.74, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 17, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 600 $42.39 $25,434.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,542,248

F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $42.04 to $42.79, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 17, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,000 $43.43 $86,860.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,542,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $42.96 to $43.74, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 17, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 5,000 $42.40 $212,000.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,544,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $41.94 to $42.92, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 17, 2020 Filed Aug 19, 2020 20:06 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 500 $40.95 $20,475.00
Disclosure

SEC source: 0001447362-20-000177 · wf-form4_159786754776305.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,549,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $40.76 to $41.47, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 13, 2020 Filed Aug 14, 2020 20:09 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,000 $40.91 $40,909.00
Disclosure

SEC source: 0001447362-20-000175 · wf-form4_159743570029800.xml · nonDerivative · entry 5

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,550,348

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $40.690 to $41.110, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 13, 2020 Filed Aug 14, 2020 20:09 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 200 $41.70 $8,340.00
Disclosure

SEC source: 0001447362-20-000175 · wf-form4_159743570029800.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,551,348

F4 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

Read SEC document
August 13, 2020 Filed Aug 14, 2020 20:09 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 7,300 $40.97 $299,102.90
Disclosure

SEC source: 0001447362-20-000175 · wf-form4_159743570029800.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,551,548

F4 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $40.670 to $41.635, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 12, 2020 Filed Aug 14, 2020 20:09 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 4,200 $41.90 $175,992.60
Disclosure

SEC source: 0001447362-20-000175 · wf-form4_159743570029800.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,558,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F3 · price: This transaction was executed in multiple trades at prices ranging from $41.520 to $42.240, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 12, 2020 Filed Aug 14, 2020 20:09 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 800 $40.30 $32,237.60
Disclosure

SEC source: 0001447362-20-000175 · wf-form4_159743570029800.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,563,048

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $39.940 to $40.765, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 10, 2020 Filed Aug 12, 2020 21:58 UTC SaleCommon Stock 25,000 $42.01 $1,050,305.00
Disclosure

SEC source: 0001447362-20-000172 · wf-form4_159726950602439.xml · nonDerivative · entry 1

KABAKOFF DAVID S · CIK 0001024008 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By L.P.

Disclosed balance after: 1,133,577

F1 · kind: The transaction on this Form 4 was made pursuant to a Rule 10b5-1 plan adopted by Sofinnova HealthQuest Partners, L.P. on May 22, 2020.

F2 · ownership.nature: Held by Sofinnova HealthQuest Partners, L.P., or HealthQuest Partners. HealthQuest Venture Management, L.L.C., or HealthQuest Management, is the general partner of HealthQuest Partners. David Kabakoff, Ph.D., the Reporting Person, is a partner of HealthQuest Management. Garheng Kong is the managing member of HealthQuest Management and has sole voting and investment power over the shares held by HealthQuest Partners. Each of HealthQuest Management, Mr. Kong and Dr. Kabakoff disclaims beneficial ownership over all shares held by HealthQuest Partners except to the extent of any pecuniary interest therein.

Read SEC document
August 07, 2020 Filed Aug 10, 2020 21:22 UTC SaleCommon Stock 3,750 $41.60 $155,992.50
Disclosure

SEC source: 0001447362-20-000170 · wf-form4_159709455926396.xml · nonDerivative · entry 3

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 856,078

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $41.025 to $41.990, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 06, 2020 Filed Aug 8, 2020 00:05 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 1,000 $41.28 $41,281.00
Disclosure

SEC source: 0001447362-20-000161 · wf-form4_159684505354964.xml · nonDerivative · entry 4

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,563,848

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $40.835 to $41.760, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 06, 2020 Filed Aug 8, 2020 00:05 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 800 $42.00 $33,598.40
Disclosure

SEC source: 0001447362-20-000161 · wf-form4_159684505354964.xml · nonDerivative · entry 3

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,564,848

F3 · kind: These transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $41.940 to $42.050, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 06, 2020 Filed Aug 8, 2020 00:05 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 6,700 $41.29 $276,649.70
Disclosure

SEC source: 0001447362-20-000161 · wf-form4_159684505354964.xml · nonDerivative · entry 2

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,565,648

F3 · kind: These transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on March 18, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $40.920 to $41.880, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 21:22 UTC SaleCommon Stock 400 $41.94 $16,775.60
Disclosure

SEC source: 0001447362-20-000170 · wf-form4_159709455926396.xml · nonDerivative · entry 2

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 859,828

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F4 · price: This transaction was executed in multiple trades at prices ranging from $41.835 to $42.020, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 21:22 UTC SaleCommon Stock 3,350 $41.27 $138,237.75
Disclosure

SEC source: 0001447362-20-000170 · wf-form4_159709455926396.xml · nonDerivative · entry 1

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 860,228

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $40.825 to $41.780, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by BioBrit, LLC (the "LLC"), of which the Reporting Person is the managing member and has voting and investment power over the shares.

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August 05, 2020 Filed Aug 8, 2020 00:05 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 5,000 $41.67 $208,360.00
Disclosure

SEC source: 0001447362-20-000161 · wf-form4_159684505354964.xml · nonDerivative · entry 1

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,572,348

F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F2 · price: This transaction was executed in multiple trades at prices ranging from $41.160 to $42.100, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

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July 22, 2020 Filed Jul 23, 2020 20:06 UTC SaleCommon Stock 1,450 $39.90 $57,855.00
Disclosure

SEC source: 0001447362-20-000155 · wf-form4_159553478080217.xml · nonDerivative · entry 5

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 863,578

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F6 · price: This transaction was executed in multiple trades at prices ranging from $39.73 to $40.12, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

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July 22, 2020 Filed Jul 23, 2020 20:06 UTC SaleCommon Stock 2,300 $39.38 $90,574.00
Disclosure

SEC source: 0001447362-20-000155 · wf-form4_159553478080217.xml · nonDerivative · entry 4

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 865,028

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F5 · price: This transaction was executed in multiple trades at prices ranging from $38.69 to $39.64, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

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July 22, 2020 Filed Jul 23, 2020 20:02 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,290 $39.86 $91,279.40
Disclosure

SEC source: 0001447362-20-000153 · wf-form4_159553453081023.xml · nonDerivative · entry 7

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,577,348

F4 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F8 · price: This transaction was executed in multiple trades at prices ranging from $39.580 to $40.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

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July 22, 2020 Filed Jul 23, 2020 20:02 UTC
MAETZOLD DEREK JDirector · Pres. & Chief Exec. Officer
SaleCommon Stock 2,710 $39.32 $106,554.49
Disclosure

SEC source: 0001447362-20-000153 · wf-form4_159553453081023.xml · nonDerivative · entry 6

MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,579,638

F4 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2020.

F7 · price: This transaction was executed in multiple trades at prices ranging from $38.580 to $39.570, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

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July 21, 2020 Filed Jul 23, 2020 20:06 UTC SaleCommon Stock 2 $42.84 $85.68
Disclosure

SEC source: 0001447362-20-000155 · wf-form4_159553478080217.xml · nonDerivative · entry 3

BRADBURY DANIEL · CIK 0001236397 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By LLC

Disclosed balance after: 867,328

F1 · kind: The transactions on this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by BioBrit, LLC (the "LLC") on March 13, 2020.

F3 · ownership.nature: Held by the LLC, of which the Reporting Person is the managing member and has voting and investment power over the shares.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.