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Nasdaq · USD

CRSP

CRISPR Therapeutics AG

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Tapewire entity
3852
SEC CIK
0001674416
Parsed reports
491

Last 12 months

Inside the activity.

0 purchase rows · 27 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202503
Jan 202607
Feb 202602
Mar 2026010
Apr 202600
May 202601
Jun 202600
Jul 202600
Aug 202600
Sep 202602
Oct 202602

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 11, 2019 Filed Jun 14, 2019 00:49 UTC GrantStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $43.52 $0.00
Disclosure

SEC source: 0000899243-19-016947 · doc4.xml · derivative · entry 1

High Katherine A · CIK 0001631248 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2029-06-11

F1 · derivative.exercise_date: This option was granted on June 11, 2019 with respect to 30,000 Common Shares with 100% of the shares vesting in 36 equal monthly installments.

Read SEC document
June 11, 2019 Filed Jun 13, 2019 21:05 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $43.52 $0.00
Disclosure

SEC source: 0000899243-19-016847 · doc4.xml · derivative · entry 1

Bolzon Bradley J PhD · CIK 0001354345 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 15,000

Underlying: Common Shares · 15,000 shares

Expires 2029-06-11

F2 · shares: The Reporting Person is a managing member of Versant Venture Management, LLC and pursuant to agreement with Versant Venture Management, LLC, the Reporting Person is deemed to hold these securities for the benefit of Versant Venture Management, LLC. Accordingly, Versant Venture Management, LLC may be deemed to be the indirect beneficial owner of these securities, and the Reporting Person may be deemed to indirectly beneficially own the securities through his interest in Versant Venture Management, LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

F1 · derivative.exercise_date: This option was granted on June 11, 2019 with respect to 15,000 Common Shares with 100% of the shares vesting in 12 equal monthly installments beginning on June 30, 2019; provided that the last installment will vest on the earlier of (i) the one year anniversary of the date of grant or (ii) the date of the 2020 Annual General Meeting of Shareholders.

F2 · derivative.underlying_shares: The Reporting Person is a managing member of Versant Venture Management, LLC and pursuant to agreement with Versant Venture Management, LLC, the Reporting Person is deemed to hold these securities for the benefit of Versant Venture Management, LLC. Accordingly, Versant Venture Management, LLC may be deemed to be the indirect beneficial owner of these securities, and the Reporting Person may be deemed to indirectly beneficially own the securities through his interest in Versant Venture Management, LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

F2 · balance_after: The Reporting Person is a managing member of Versant Venture Management, LLC and pursuant to agreement with Versant Venture Management, LLC, the Reporting Person is deemed to hold these securities for the benefit of Versant Venture Management, LLC. Accordingly, Versant Venture Management, LLC may be deemed to be the indirect beneficial owner of these securities, and the Reporting Person may be deemed to indirectly beneficially own the securities through his interest in Versant Venture Management, LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

F2 · ownership.nature: The Reporting Person is a managing member of Versant Venture Management, LLC and pursuant to agreement with Versant Venture Management, LLC, the Reporting Person is deemed to hold these securities for the benefit of Versant Venture Management, LLC. Accordingly, Versant Venture Management, LLC may be deemed to be the indirect beneficial owner of these securities, and the Reporting Person may be deemed to indirectly beneficially own the securities through his interest in Versant Venture Management, LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

Read SEC document
June 11, 2019 Filed Jun 13, 2019 21:07 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $43.52 $0.00
Disclosure

SEC source: 0001209191-19-036843 · doc4.xml · derivative · entry 1

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2029-06-11

F1 · derivative.exercise_date: This option was granted on June 11, 2019 with respect to 15,000 Common Shares with 100% of the shares vesting in 12 equal monthly installments beginning on June 30, 2019; provided that the last installment will vest on the earlier of (i) the one year anniversary of the date of grant or (ii) the date of the 2020 Annual General Meeting of Shareholders.

Read SEC document
June 11, 2019 Filed Jun 13, 2019 21:04 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $43.52 $0.00
Disclosure

SEC source: 0000899243-19-016845 · doc4.xml · derivative · entry 1

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Shares · 15,000 shares

Expires 2029-06-11

F1 · derivative.exercise_date: This option was granted on June 11, 2019 with respect to 15,000 Common Shares with 100% of the shares vesting in 12 equal monthly installments beginning on June 30, 2019; provided that the last installment will vest on the earlier of (i) the one year anniversary of the date of grant or (ii) the date of the 2020 Annual General Meeting of Shareholders.

Read SEC document
June 11, 2019 Filed Jun 13, 2019 21:04 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $43.52 $0.00
Disclosure

SEC source: 0000899243-19-016843 · doc4.xml · derivative · entry 1

George Simeon · CIK 0001595117 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Shares · 15,000 shares

Expires 2029-06-11

F1 · derivative.exercise_date: This option was granted on June 11, 2019 with respect to 15,000 Common Shares with 100% of the shares vesting in 12 equal monthly installments beginning on June 30, 2019; provided that the last installment will vest on the earlier of (i) the one year anniversary of the date of grant or (ii) the date of the 2020 Annual General Meeting of Shareholders.

Read SEC document
June 10, 2019 Filed Jun 12, 2019 20:16 UTC
Novak RodgerDirector · President
SaleCommon Shares 50,000 $45.00 $2,250,000.00
Disclosure

SEC source: 0000899243-19-016636 · doc4.xml · nonDerivative · entry 1

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 898,007

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
June 01, 2019 Filed Jun 4, 2019 20:25 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Tax withholdingCommon Shares 741 $35.57 $26,357.37
Disclosure

SEC source: 0000899243-19-015475 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,801

F1 · kind: On December 1, 2017, the reporting person was granted 26,667 restricted stock units. On June 1, 2019, 1,667 restricted stock units vested, and the reporting person forfeited 741 common shares to the issuer to satisfy tax withholding obligations.

Read SEC document
April 29, 2019 Filed May 1, 2019 20:05 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 20,000 $0.00 Strike: $1.81 $0.00
Disclosure

SEC source: 0000899243-19-011567 · doc4.xml · derivative · entry 3

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,058

Underlying: Common Shares · 20,000 shares

Expires 2025-09-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option was granted on September 10, 2015 with respect to 321,712 Common Shares with 120,640 of the shares vested on August 1, 2016, the first anniversary of employment commencement, and the remainder vest in equal 36 monthly installments thereafter.

Read SEC document
April 29, 2019 Filed May 1, 2019 20:05 UTC
Kulkarni SamarthDirector · Chief Executive Officer
SaleCommon Shares 20,000 $42.03 $840,600.00
Disclosure

SEC source: 0000899243-19-011567 · doc4.xml · nonDerivative · entry 2

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,542

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $42.00 to $42.16, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
April 29, 2019 Filed May 1, 2019 20:05 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Exercise / conversionCommon Shares 20,000 $1.81 $36,200.00
Disclosure

SEC source: 0000899243-19-011567 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,542

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:11 UTC
Kulkarni SamarthDirector · Chief Executive Officer
GrantStock Option (Right to Buy) · Derivative 250,000 $0.00 Strike: $40.87 $0.00
Disclosure

SEC source: 0000899243-19-006647 · doc4.xml · derivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Shares · 250,000 shares

Expires 2029-03-05

F1 · derivative.exercise_date: This option was granted on March 5, 2019 with respect to 250,000 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of April 5, 2019.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:17 UTC
Klein Lawrence OttoChief Business Officer
GrantStock Option (Right to Buy) · Derivative 45,000 $0.00 Strike: $40.87 $0.00
Disclosure

SEC source: 0000899243-19-006657 · doc4.xml · derivative · entry 1

Klein Lawrence Otto · CIK 0001762583 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Shares · 45,000 shares

Expires 2029-03-05

F1 · derivative.exercise_date: This option was granted on March 5, 2019 with respect to 45,000 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of April 5, 2019.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:14 UTC
TOMSICEK MICHAEL JOHNChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $40.87 $0.00
Disclosure

SEC source: 0000899243-19-006653 · doc4.xml · derivative · entry 1

TOMSICEK MICHAEL JOHN · CIK 0001570392 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Shares · 75,000 shares

Expires 2029-03-05

F1 · derivative.exercise_date: This option was granted on March 5, 2019 with respect to 75,000 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of April 5, 2019.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:14 UTC
KASINGER JAMES R.General Counsel and Secretary
GrantStock Option (Right to Buy) · Derivative 65,000 $0.00 Strike: $40.87 $0.00
Disclosure

SEC source: 0000899243-19-006652 · doc4.xml · derivative · entry 1

KASINGER JAMES R. · CIK 0001708172 · General Counsel and Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Shares · 65,000 shares

Expires 2029-03-05

F1 · derivative.exercise_date: This option was granted on March 5, 2019 with respect to 65,000 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of April 5, 2019.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:12 UTC
Ho Tony WSee Remarks
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $40.87 $0.00
Disclosure

SEC source: 0000899243-19-006649 · doc4.xml · derivative · entry 2

Ho Tony W · CIK 0001713637 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Shares · 75,000 shares

Expires 2029-03-05

F2 · derivative.exercise_date: This option was granted on March 5, 2019 with respect to 75,000 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of April 5, 2019.

Read SEC document
March 05, 2019 Filed Mar 7, 2019 21:12 UTC
Ho Tony WSee Remarks
GrantRestricted Stock Units 10,000 $40.87 $408,700.00
Disclosure

SEC source: 0000899243-19-006649 · doc4.xml · nonDerivative · entry 1

Ho Tony W · CIK 0001713637 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,869

F1 · shares: This restricted stock unit award was granted on March 5, 2019 with respect to 10,000 Common Shares, with (i) 3,333 shares vesting on March 5, 2020, (ii) 3,333 shares vesting on March 5, 2021, and (iii) 3,334 shares vesting on March 5, 2022. Each restricted stock unit represents a contingent right to receive one CRSP Common Share.

Read SEC document
March 04, 2019 Filed Mar 5, 2019 22:59 UTC
Novak RodgerDirector · President
SaleCommon Shares 3,500 $42.03 $147,105.00
Disclosure

SEC source: 0000899243-19-006186 · doc4.xml · nonDerivative · entry 4

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 948,007

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
March 04, 2019 Filed Mar 5, 2019 22:59 UTC
Novak RodgerDirector · President
SaleCommon Shares 8,912 $41.29 $367,948.85
Disclosure

SEC source: 0000899243-19-006186 · doc4.xml · nonDerivative · entry 3

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 951,507

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.00 to $41.99, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 04, 2019 Filed Mar 5, 2019 22:59 UTC
Novak RodgerDirector · President
SaleCommon Shares 64,115 $40.24 $2,580,186.36
Disclosure

SEC source: 0000899243-19-006186 · doc4.xml · nonDerivative · entry 2

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 960,419

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.95, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 01, 2019 Filed Mar 5, 2019 22:59 UTC
Novak RodgerDirector · President
SaleCommon Shares 8,693 $40.01 $347,796.50
Disclosure

SEC source: 0000899243-19-006186 · doc4.xml · nonDerivative · entry 1

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,024,534

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.04, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 01, 2019 Filed Mar 5, 2019 22:57 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Tax withholdingCommon Shares 748 $39.97 $29,897.56
Disclosure

SEC source: 0000899243-19-006182 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 166,542

F1 · kind: On December 1, 2017, the reporting person was granted 26,667 restricted stock units. On March 1, 2019, 1,667 restricted stock units vested, and the reporting person forfeited 748 common shares to the issuer to satisfy tax withholding obligations.

Read SEC document
February 25, 2019 Filed Feb 27, 2019 21:10 UTC
Novak RodgerDirector · President
SaleCommon Shares 14,780 $40.00 $591,232.52
Disclosure

SEC source: 0000899243-19-005001 · doc4.xml · nonDerivative · entry 1

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,033,227

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.025, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
January 09, 2019 Filed Jan 10, 2019 21:09 UTC
Novak RodgerDirector · President
SaleCommon Shares 82,690 $35.01 $2,894,976.90
Disclosure

SEC source: 0000899243-19-000956 · doc4.xml · nonDerivative · entry 2

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,048,007

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.00 to $35.105, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
January 08, 2019 Filed Jan 10, 2019 21:09 UTC
Novak RodgerDirector · President
SaleCommon Shares 17,310 $35.09 $607,407.90
Disclosure

SEC source: 0000899243-19-000956 · doc4.xml · nonDerivative · entry 1

Novak Rodger · CIK 0001682017 · Director · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,130,697

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.00 to $35.24, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 21:32 UTC
Klein Lawrence OttoChief Business Officer
GrantStock Option (Right to Buy) · Derivative 20,000 $0.00 Strike: $29.87 $0.00
Disclosure

SEC source: 0000899243-19-000296 · doc4.xml · derivative · entry 2

Klein Lawrence Otto · CIK 0001762583 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Shares · 20,000 shares

Expires 2029-01-01

F3 · derivative.exercise_date: 25% of the option shall vest on January 2, 2020, and the remaining 75% of the shares shall vest in 36 equal monthly installments on the final day of each month.

Read SEC document
January 02, 2019 Filed Jan 3, 2019 21:32 UTC
Klein Lawrence OttoChief Business Officer
GrantRestricted Stock Units 20,000 $29.87 $597,400.00
Disclosure

SEC source: 0000899243-19-000296 · doc4.xml · nonDerivative · entry 1

Klein Lawrence Otto · CIK 0001762583 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

F1 · security: Each restricted stock unit represents a contingent right to receive one CRSP common share.

F2 · security: The restricted stock units shall vest in full on January 2, 2021, subject to continued employment with the company.

Read SEC document
December 27, 2018 Filed Dec 28, 2018 21:34 UTC PurchaseCommon Shares 27,461 $24.95 $685,116.25
Disclosure

SEC source: 0001209191-18-064322 · doc4.xml · nonDerivative · entry 2

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,380,940

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F3 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.85 and $25.00.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

Read SEC document
December 26, 2018 Filed Dec 28, 2018 21:34 UTC PurchaseCommon Shares 12,737 $24.89 $317,077.43
Disclosure

SEC source: 0001209191-18-064322 · doc4.xml · nonDerivative · entry 1

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,353,479

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F2 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.69 and $25.00.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

Read SEC document
December 24, 2018 Filed Dec 26, 2018 21:35 UTC PurchaseCommon Shares 53,655 $24.97 $1,339,695.60
Disclosure

SEC source: 0001209191-18-064099 · doc4.xml · nonDerivative · entry 4

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,340,742

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F5 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.82 and $25.00.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

Read SEC document
December 24, 2018 Filed Dec 26, 2018 21:35 UTC PurchaseCommon Shares 11,742 $23.18 $272,139.64
Disclosure

SEC source: 0001209191-18-064099 · doc4.xml · nonDerivative · entry 3

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,287,087

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F4 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $23.02 and $23.25.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

Read SEC document
December 24, 2018 Filed Dec 26, 2018 21:35 UTC PurchaseCommon Shares 2,603 $22.91 $59,646.96
Disclosure

SEC source: 0001209191-18-064099 · doc4.xml · nonDerivative · entry 2

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,275,345

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F3 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $22.69 and $23.00.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

Read SEC document
December 21, 2018 Filed Dec 26, 2018 21:35 UTC PurchaseCommon Shares 22,742 $22.58 $513,477.97
Disclosure

SEC source: 0001209191-18-064099 · doc4.xml · nonDerivative · entry 1

Vertex Pharmaceuticals (Europe) Ltd · CIK 0001761216 · 10% owner

VERTEX PHARMACEUTICALS INC / MA · CIK 0000875320 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,272,742

F1 · shares: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

F2 · price: Represents the weighted average price. These shares were purchased in multiple transactions at prices ranging from $22.46 and $22.70.

F1 · balance_after: Shares are directly held by Vertex Pharmaceuticals (Europe) Limited ("Vertex Europe"). Vertex Europe is an indirect wholly owned subsidiary of Vertex Pharmaceuticals Inc. Vertex Pharmaceuticals Inc. may be deemed to beneficially own the shares owned directly by Vertex Europe.

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December 18, 2018 Filed Dec 19, 2018 21:22 UTC SaleCommon Shares 69,925 $29.70 $2,077,101.15
Disclosure

SEC source: 0000905718-18-000981 · crisprfm4_dec172018.xml · nonDerivative · entry 2

EMSTER KURT VON · CIK 0001252524 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 1,164,268

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.18 to $30.62 per share, inclusive.

F2 · price: The Reporting Person undertakes to provide to Issuer any security holder of Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth herein.

F3 · ownership.nature: Shares are held by ABV VI. Abingworth LLP is the investment manager of ABV VI and has been delegated with all investment and dispositive power over the securities held by ABV VI. Reporting Person is a member of the investment committee of Abingworth LLP, which approves investment and voting decisions by a majority vote, and no individual member has the sole control or voting power over the shares held by ABV VI.

F4 · ownership.nature: From time to time, the investment committee may delegate investment and voting authority over certain securities held by ABV VI and ABE to employees of Abingworth subject to the supervision and oversight of the investment committee, including any limits on such authority imposed by the investment committee in its discretion and the right of the investment committee to revoke such authority at any time. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any.

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December 18, 2018 Filed Jan 18, 2019 21:32 UTC Amendment SaleCommon Shares 62,925 $29.70 $1,869,168.25
Disclosure

SEC source: 0000905718-19-000065 · crisprfm4a_dec192018.xml · nonDerivative · entry 1

EMSTER KURT VON · CIK 0001252524 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 1,171,268

F1 · shares: This amended Form 4 is being filed to correct the number of shares sold on December 18, 2018 and the number of shares beneficially owned following the transaction.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.18 to $30.62 per share, inclusive.

F3 · price: The Reporting Person undertakes to provide to Issuer any security holder of Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth herein.

F1 · balance_after: This amended Form 4 is being filed to correct the number of shares sold on December 18, 2018 and the number of shares beneficially owned following the transaction.

F4 · ownership.nature: Shares are held by ABV VI. Abingworth LLP is the investment manager of ABV VI and has been delegated with all investment and dispositive power over the securities held by ABV VI. Reporting Person is a member of the investment committee of Abingworth LLP, which approves investment and voting decisions by a majority vote, and no individual member has the sole control or voting power over the shares held by ABV VI.

F5 · ownership.nature: From time to time, the investment committee may delegate investment and voting authority over certain securities held by ABV VI and ABE to employees of Abingworth subject to the supervision and oversight of the investment committee, including any limits on such authority imposed by the investment committee in its discretion and the right of the investment committee to revoke such authority at any time. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any.

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December 17, 2018 Filed Dec 19, 2018 21:22 UTC SaleCommon Shares 3,009 $33.17 $99,797.10
Disclosure

SEC source: 0000905718-18-000981 · crisprfm4_dec172018.xml · nonDerivative · entry 1

EMSTER KURT VON · CIK 0001252524 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 1,234,193

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $33.03 to $33.29 per share, inclusive.

F2 · price: The Reporting Person undertakes to provide to Issuer any security holder of Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth herein.

F3 · ownership.nature: Shares are held by ABV VI. Abingworth LLP is the investment manager of ABV VI and has been delegated with all investment and dispositive power over the securities held by ABV VI. Reporting Person is a member of the investment committee of Abingworth LLP, which approves investment and voting decisions by a majority vote, and no individual member has the sole control or voting power over the shares held by ABV VI.

F4 · ownership.nature: From time to time, the investment committee may delegate investment and voting authority over certain securities held by ABV VI and ABE to employees of Abingworth subject to the supervision and oversight of the investment committee, including any limits on such authority imposed by the investment committee in its discretion and the right of the investment committee to revoke such authority at any time. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any.

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December 07, 2018 Filed Dec 11, 2018 21:29 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Exercise / conversionStock Options (Right to Buy) · Derivative 21,500 $0.00 Strike: $1.81 $0.00
Disclosure

SEC source: 0000899243-18-030649 · doc4.xml · derivative · entry 2

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 243,058

Underlying: Common Shares · 21,500 shares

Expires 2025-09-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option was granted on September 10, 2015 with respect to 321,712 Common Shares with 120,640 of the shares vested on August 1, 2016, the first anniversary of employment commencement, and the remainder vest in equal 36 monthly installments thereafter.

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December 07, 2018 Filed Dec 11, 2018 21:29 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Exercise / conversionCommon Shares 21,500 $1.81 $38,915.00
Disclosure

SEC source: 0000899243-18-030649 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,290

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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December 01, 2018 Filed Dec 3, 2018 22:29 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Tax withholdingCommon Shares 741 $38.33 $28,402.53
Disclosure

SEC source: 0000899243-18-029962 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,790

F1 · kind: On December 1, 2017, the reporting person was granted 26,667 restricted stock units. On December 1, 2018, 1,666 restricted stock units vested, and the reporting person forfeited 741 common shares to the issuer to satisfy tax withholding obligations.

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November 21, 2018 Filed Dec 7, 2017 09:57 UTC SaleCommon Stock 80,000 $19.25 $1,540,000.00
Disclosure

SEC source: 0001209191-17-064325 · doc4.xml · nonDerivative · entry 13

CELGENE CORP /DE/ · CIK 0000816284 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See explanation of responses

Disclosed balance after: 4,173,019

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from: $17.86 to $18.57 on 11/16/2017; $18.30 to $18.65 on 11/17/2017; $18.60 to $19.26 on 11/20/2017; $19.02 to $19.46 on 11/21/2017; $19.20 to $20.01 on 11/22/2017; $19.84 to $20.27 on 11/24/2017; $19.41 to $20.20 on 11/27/2017; $19.00 to $19.76 on 11/28/2017; $19.20 to $19.39 on 11/29/2017; $19.00 to $19.20 on 11/30/2017; $19.02 to $19.22 on 12/1/2017; and $19.20 to 19.64 on 12/4/2017, inclusive. The reporting person undertakes to provide any security holder of the Issuer or the staff of the Securities Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

F2 · ownership.nature: These securities are held of record by Celgene Alpine Investment Co. III, LLC, an indirectly wholly-owned subsidiary of Celgene Corporation ("Celgene"). Celgene may be deemed to have voting and investment power over these securities and as a result may be deemed to have beneficial ownership over such securities.

F3 · ownership.nature: Celgene disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that Celgene is a beneficial owner of such securities for the purpose of Section 16 and the Exchange Act, or for any other purpose.

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September 01, 2018 Filed Sep 4, 2018 22:33 UTC
Kulkarni SamarthDirector · Chief Executive Officer
Tax withholdingCommon Shares 741 $56.67 $41,992.47
Disclosure

SEC source: 0000899243-18-023753 · doc4.xml · nonDerivative · entry 1

Kulkarni Samarth · CIK 0001682019 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,531

F1 · kind: On December 1, 2017, the reporting person was granted 26,667 restricted stock units. On September 1, 2018, 1,667 restricted stock units vested, and the reporting person forfeited 741 common shares to the issuer to satisfy tax withholding obligations.

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August 02, 2018 Filed Aug 3, 2018 21:43 UTC
Ho Tony WSee Remarks
Tax withholdingCommon Shares 14,631 $48.43 $708,579.33
Disclosure

SEC source: 0000899243-18-021415 · doc4.xml · nonDerivative · entry 2

Ho Tony W · CIK 0001713637 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,869

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August 01, 2018 Filed Aug 3, 2018 21:43 UTC
Ho Tony WSee Remarks
Exercise / conversionRestricted Stock Units · Derivative 37,500 $0.00 $0.00
Disclosure

SEC source: 0000899243-18-021415 · doc4.xml · derivative · entry 3

Ho Tony W · CIK 0001713637 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,500

Underlying: Common Shares · 37,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of CRSP Common Shares.

F2 · derivative.exercise_date: On August 1, 2017, the reporting person was granted 75,000 restricted stock units that vest in two equal annual installments on 8/1/2018 and 8/1/2019.

F2 · derivative.expiration_date: On August 1, 2017, the reporting person was granted 75,000 restricted stock units that vest in two equal annual installments on 8/1/2018 and 8/1/2019.

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August 01, 2018 Filed Aug 3, 2018 21:43 UTC
Ho Tony WSee Remarks
Exercise / conversionCommon Shares 37,500 Not disclosed Not disclosed
Disclosure

SEC source: 0000899243-18-021415 · doc4.xml · nonDerivative · entry 1

Ho Tony W · CIK 0001713637 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of CRSP Common Shares.

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July 05, 2018 Filed Jul 5, 2018 22:25 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 1,684 $0.00 Strike: $5.59 $0.00
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · derivative · entry 6

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 86,333

Underlying: Common Shares · 1,684 shares

Expires 2025-11-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option was granted on November 4, 2015 with respect to 93,833 Common Shares with 100% of the shares vesting in 48 equal monthly installments thereafter.

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July 05, 2018 Filed Jul 5, 2018 22:25 UTC SaleCommon Shares 1,684 $62.00 $104,408.00
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · nonDerivative · entry 4

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

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July 05, 2018 Filed Jul 5, 2018 22:25 UTC Exercise / conversionCommon Shares 1,684 $5.59 $9,413.56
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · nonDerivative · entry 3

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,684

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 03, 2018 Filed Jul 5, 2018 22:25 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 5,816 $0.00 Strike: $5.59 $0.00
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · derivative · entry 5

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,017

Underlying: Common Shares · 5,816 shares

Expires 2025-11-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option was granted on November 4, 2015 with respect to 93,833 Common Shares with 100% of the shares vesting in 48 equal monthly installments thereafter.

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July 03, 2018 Filed Jul 5, 2018 22:25 UTC SaleCommon Shares 5,816 $62.00 $360,592.00
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · nonDerivative · entry 2

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

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July 03, 2018 Filed Jul 5, 2018 22:25 UTC Exercise / conversionCommon Shares 5,816 $5.59 $32,511.44
Disclosure

SEC source: 0000899243-18-019501 · doc4.xml · nonDerivative · entry 1

CAGNONI PABLO J · CIK 0001205703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,816

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 15, 2018 Filed Jun 16, 2018 01:46 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $59.31 $0.00
Disclosure

SEC source: 0001209191-18-038217 · doc4.xml · derivative · entry 1

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Shares · 15,000 shares

Expires 2028-06-15

F1 · derivative.exercise_date: This option was granted on June 15, 2018 with respect to 15,000 Common Shares with 100% of the shares vesting in 12 equal monthly installments beginning May 30, 2018.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.