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Nasdaq · USD

COLL

COLLEGIUM PHARMACEUTICAL, INC

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Tapewire entity
5169
SEC CIK
0001267565
Parsed reports
359

Last 12 months

Inside the activity.

0 purchase rows · 14 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202503
Dec 202503
Jan 202600
Feb 202600
Mar 202604
Apr 202600
May 202604
Jun 202600
Jul 202600
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 08, 2026 Filed Jun 10, 2026 20:10 UTC
SANTINI GINODirector
Exercise / conversionStock Option (Right to Purchase) · Derivative 8,700 $0.00 Strike: $16.49 $0.00
Disclosure

SEC source: 0001276038-26-000006 · form4-06102026_040601.xml · derivative · entry 2

SANTINI GINO · CIK 0001276038 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,700 shares

Expires 2026-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option is fully vested and exercisable.

Read SEC document
June 08, 2026 Filed Jun 10, 2026 20:10 UTC
SANTINI GINODirector
Exercise / conversionCommon Stock 8,700 $16.49 $143,463.00
Disclosure

SEC source: 0001276038-26-000006 · form4-06102026_040601.xml · nonDerivative · entry 1

SANTINI GINO · CIK 0001276038 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 112,483

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:05 UTC SaleCommon Stock 20 $34.05 $681.00
Disclosure

SEC source: 0001296771-26-000004 · form4-05202026_040501.xml · nonDerivative · entry 1

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,952

Read SEC document
May 15, 2026 Filed May 18, 2026 20:15 UTC Exercise / conversionStock Option (Right to Purchase) · Derivative 8,700 $0.00 Strike: $16.49 $0.00
Disclosure

SEC source: 0001296771-26-000002 · form4-05182026_040512.xml · derivative · entry 6

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,700 shares

Expires 2026-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option is fully vested and exercisable.

Read SEC document
May 15, 2026 Filed May 18, 2026 20:15 UTC SaleCommon Stock 4,127 $34.54 $142,546.58
Disclosure

SEC source: 0001296771-26-000002 · form4-05182026_040512.xml · nonDerivative · entry 3

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,972

Read SEC document
May 15, 2026 Filed May 18, 2026 20:15 UTC Exercise / conversionCommon Stock 8,700 $16.49 $143,463.00
Disclosure

SEC source: 0001296771-26-000002 · form4-05182026_040512.xml · nonDerivative · entry 2

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 88,099

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC
Lurker NancyDirector
GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001450485-26-000009 · form4-05182026_040516.xml · nonDerivative · entry 1

Lurker Nancy · CIK 0001450485 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,758

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001296771-26-000002 · form4-05182026_040512.xml · nonDerivative · entry 1

Freund John Gordon · CIK 0001296771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,399

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC
SANTINI GINODirector
GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001276038-26-000002 · form4-05182026_040507.xml · nonDerivative · entry 1

SANTINI GINO · CIK 0001276038 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103,783

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001606244-26-000002 · form4-05182026_040514.xml · nonDerivative · entry 1

Paya Carlos V · CIK 0001606244 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,323

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC GrantCommon Stock 17,482 $0.00 $0.00
Disclosure

SEC source: 0002134015-26-000005 · form4-05182026_040517.xml · nonDerivative · entry 1

Glancy Donovan Michael · CIK 0002134015 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,482

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. 8,741 of the RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders; 8,741 of the RSUs vest on May 14, 2027, in each case subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001254705-26-000004 · form4-05182026_040510.xml · nonDerivative · entry 1

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,000

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 14, 2026 Filed May 18, 2026 20:15 UTC GrantCommon Stock 8,741 $0.00 $0.00
Disclosure

SEC source: 0001825625-26-000002 · form4-05182026_040509.xml · nonDerivative · entry 1

Balice-Gordon Rita J. · CIK 0001825625 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 61,370

F1 · kind: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs vest on the earlier of May 14, 2027, or the date of the Issuer's 2027 Annual Meeting of Shareholders, subject to the director's continued service with the Issuer. The RSUs will be settled on such date, or, upon the election of the director, on the earlier of the end of the director's service on the Board of Directors, the director's death or disability, or a change in control of the Issuer, in shares of the Issuer's common stock.

Read SEC document
May 13, 2026 Filed May 15, 2026 20:05 UTC
Lurker NancyDirector
SaleCommon Stock 4,500 $35.97 $161,860.95
Disclosure

SEC source: 0001450485-26-000007 · form4-05152026_040505.xml · nonDerivative · entry 1

Lurker Nancy · CIK 0001450485 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,017

F1 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $35.55 to $36.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 11, 2026 Filed May 13, 2026 20:05 UTC Exercise / conversionStock Option (Right to Purchase) · Derivative 8,700 $0.00 Strike: $16.49 $0.00
Disclosure

SEC source: 0001254705-26-000002 · form4-05132026_040501.xml · derivative · entry 3

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,700 shares

Expires 2026-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option is fully vested and exercisable.

Read SEC document
May 11, 2026 Filed May 13, 2026 20:05 UTC SaleCommon Stock 8,700 $37.18 $323,491.23
Disclosure

SEC source: 0001254705-26-000002 · form4-05132026_040501.xml · nonDerivative · entry 2

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,259

F1 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $37.18 to $37.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 11, 2026 Filed May 13, 2026 20:05 UTC Exercise / conversionCommon Stock 8,700 $16.49 $143,463.00
Disclosure

SEC source: 0001254705-26-000002 · form4-05132026_040501.xml · nonDerivative · entry 1

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,959

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 18, 2026 Filed Mar 20, 2026 21:14 UTC
Dieter DavidEVP & General Counsel
SaleCommon Stock 13,976 $34.92 $488,099.22
Disclosure

SEC source: 0002061438-26-000006 · form4-03202026_090345.xml · nonDerivative · entry 1

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 77,071

F1 · kind: The transaction reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2025.

F2 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $34.74 to $35.39, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 17, 2026 Filed Apr 3, 2026 20:46 UTC
Dieter DavidEVP & General Counsel
Tax withholdingCommon Stock 8,840 $35.72 $315,764.80
Disclosure

SEC source: 0002061438-26-000009 · form4-04032026_080415.xml · nonDerivative · entry 1

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,231

F1 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of restricted stock units.

Read SEC document
March 09, 2026 Filed Mar 11, 2026 20:10 UTC
Dieter DavidEVP & General Counsel
SaleCommon Stock 6,224 $36.65 $228,109.60
Disclosure

SEC source: 0002061438-26-000004 · form4-03112026_080318.xml · nonDerivative · entry 1

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,047

F1 · kind: The transaction reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2025.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 21:29 UTC
Dreyer ScottEVP & Chief Commercial Officer
SaleCommon Stock 3,559 $40.99 $145,879.50
Disclosure

SEC source: 0001746251-26-000004 · form4-03052026_090346.xml · nonDerivative · entry 2

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,770

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

F3 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $40.84 to $41.35, inclusive.

Read SEC document
March 03, 2026 Filed Mar 5, 2026 21:29 UTC
Dreyer ScottEVP & Chief Commercial Officer
SaleCommon Stock 46,417 $40.36 $1,873,557.22
Disclosure

SEC source: 0001746251-26-000004 · form4-03052026_090346.xml · nonDerivative · entry 1

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,329

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

F2 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $39.835 to $40.82, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dieter DavidEVP & General Counsel
Tax withholdingCommon Stock 2,781 $46.75 $130,011.75
Disclosure

SEC source: 0002061438-26-000002 · form4-02122026_040219.xml · nonDerivative · entry 3

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 97,271

F4 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of PSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dieter DavidEVP & General Counsel
GrantCommon Stock 9,005 $0.00 $0.00
Disclosure

SEC source: 0002061438-26-000002 · form4-02122026_040219.xml · nonDerivative · entry 2

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,052

F3 · shares: Effective February 10, 2026, the Compensation Committee of the Board of Directors of the Issuer determined that performance-vesting criteria were met with regard to an aggregate of 9,005 performance share units ("PSUs") granted in the Issuer's 2025 fiscal year.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dieter DavidEVP & General Counsel
GrantCommon Stock 22,194 $0.00 $0.00
Disclosure

SEC source: 0002061438-26-000002 · form4-02122026_040219.xml · nonDerivative · entry 1

Dieter David · CIK 0002061438 · EVP & General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,047

F1 · shares: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. One-third (33%) of the RSUs shall vest on February 10, 2027, with the balance of the RSUs vesting in equal annual installments over the following two-year period, subject to the Reporting Person's continued service with the Issuer. The RSUs will be settled on each applicable vesting date in shares of the Issuer's common stock.

F2 · balance_after: Includes 404 shares acquired on January 16, 2026 under the Issuer's employee stock purchase plan.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 16:30 UTC
Tupper ColleenEVP & Chief Financial Officer
Tax withholdingCommon Stock 26,679 $46.75 $1,247,243.25
Disclosure

SEC source: 0001862082-26-000002 · form4-02122026_040203.xml · nonDerivative · entry 4

Tupper Colleen · CIK 0001862082 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 147,282

F4 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of RSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 16:30 UTC
Tupper ColleenEVP & Chief Financial Officer
Tax withholdingCommon Stock 11,861 $46.75 $554,501.75
Disclosure

SEC source: 0001862082-26-000002 · form4-02122026_040203.xml · nonDerivative · entry 3

Tupper Colleen · CIK 0001862082 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 173,961

F3 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of PSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 16:30 UTC
Tupper ColleenEVP & Chief Financial Officer
GrantCommon Stock 32,734 $0.00 $0.00
Disclosure

SEC source: 0001862082-26-000002 · form4-02122026_040203.xml · nonDerivative · entry 2

Tupper Colleen · CIK 0001862082 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 185,822

F2 · shares: Effective February 10, 2026, the Compensation Committee of the Board of Directors of the Issuer determined that performance-vesting criteria were met with regard to an aggregate of 32,734 performance share units ("PSUs") granted in the Issuer's three prior fiscal years.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 16:30 UTC
Tupper ColleenEVP & Chief Financial Officer
GrantCommon Stock 26,421 $0.00 $0.00
Disclosure

SEC source: 0001862082-26-000002 · form4-02122026_040203.xml · nonDerivative · entry 1

Tupper Colleen · CIK 0001862082 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,088

F1 · shares: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. One-third (33%) of the RSUs shall vest on February 10, 2027, with the balance of the RSUs vesting in equal annual installments over the following two-year period, subject to the Reporting Person's continued service with the Issuer. The RSUs will be settled on each applicable vesting date in shares of the Issuer's common stock.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Karnani VikramDirector · President and CEO
Tax withholdingCommon Stock 11,296 $46.75 $528,088.00
Disclosure

SEC source: 0001699488-26-000002 · form4-02122026_040217.xml · nonDerivative · entry 3

Karnani Vikram · CIK 0001699488 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 197,864

F4 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of PSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Karnani VikramDirector · President and CEO
GrantCommon Stock 32,531 $0.00 $0.00
Disclosure

SEC source: 0001699488-26-000002 · form4-02122026_040217.xml · nonDerivative · entry 2

Karnani Vikram · CIK 0001699488 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 209,160

F3 · shares: Effective February 10, 2026, the Compensation Committee of the Board of Directors of the Issuer determined that performance-vesting criteria were met with regard to an aggregate of 32,531 performance share units ("PSUs") granted in the Issuer's 2025 fiscal year.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Karnani VikramDirector · President and CEO
GrantCommon Stock 79,264 $0.00 $0.00
Disclosure

SEC source: 0001699488-26-000002 · form4-02122026_040217.xml · nonDerivative · entry 1

Karnani Vikram · CIK 0001699488 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 176,629

F1 · shares: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. One-third (33%) of the RSUs shall vest on February 10, 2027, with the balance of the RSUs vesting in equal annual installments over the following two-year period, subject to the Reporting Person's continued service with the Issuer. The RSUs will be settled on each applicable vesting date in shares of the Issuer's common stock.

F2 · balance_after: Includes 376 shares acquired on July 18, 2025 under the Issuer's employee stock purchase plan.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Smith Thomas BEVP and Chief Medical Officer
Tax withholdingCommon Stock 11,538 $46.75 $539,401.50
Disclosure

SEC source: 0001748462-26-000002 · form4-02122026_040205.xml · nonDerivative · entry 4

Smith Thomas B · CIK 0001748462 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,651

F5 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of RSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Smith Thomas BEVP and Chief Medical Officer
Tax withholdingCommon Stock 5,897 $46.75 $275,684.75
Disclosure

SEC source: 0001748462-26-000002 · form4-02122026_040205.xml · nonDerivative · entry 3

Smith Thomas B · CIK 0001748462 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 102,189

F4 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of PSUs.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Smith Thomas BEVP and Chief Medical Officer
GrantCommon Stock 22,774 $0.00 $0.00
Disclosure

SEC source: 0001748462-26-000002 · form4-02122026_040205.xml · nonDerivative · entry 2

Smith Thomas B · CIK 0001748462 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,086

F3 · shares: Effective February 10, 2026, the Compensation Committee of the Board of Directors of the Issuer determined that performance-vesting criteria were met with regard to an aggregate of 22,774 performance share units ("PSUs") granted in the Issuer's three prior fiscal years.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Smith Thomas BEVP and Chief Medical Officer
GrantCommon Stock 14,268 $0.00 $0.00
Disclosure

SEC source: 0001748462-26-000002 · form4-02122026_040205.xml · nonDerivative · entry 1

Smith Thomas B · CIK 0001748462 · EVP and Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,312

F1 · shares: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. One-third (33%) of the RSUs shall vest on February 10, 2027, with the balance of the RSUs vesting in equal annual installments over the following two-year period, subject to the Reporting Person's continued service with the Issuer. The RSUs will be settled on each applicable vesting date in shares of the Issuer's common stock.

F2 · balance_after: Includes 376 and 404 shares acquired on July 18, 2025 and January 16, 2026, respectively, under the Issuer's employee stock purchase plan.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dreyer ScottEVP & Chief Commercial Officer
Tax withholdingCommon Stock 21,615 $46.75 $1,010,501.25
Disclosure

SEC source: 0001746251-26-000002 · form4-02122026_040201.xml · nonDerivative · entry 4

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,746

F4 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of RSUs.

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February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dreyer ScottEVP & Chief Commercial Officer
Tax withholdingCommon Stock 9,977 $46.75 $466,424.75
Disclosure

SEC source: 0001746251-26-000002 · form4-02122026_040201.xml · nonDerivative · entry 3

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 143,361

F3 · shares: Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of PSUs.

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February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dreyer ScottEVP & Chief Commercial Officer
GrantCommon Stock 30,702 $0.00 $0.00
Disclosure

SEC source: 0001746251-26-000002 · form4-02122026_040201.xml · nonDerivative · entry 2

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,338

F2 · shares: Effective February 10, 2026, the Compensation Committee of the Board of Directors of the Issuer determined that performance-vesting criteria were met with regard to an aggregate of 30,702 performance share units ("PSUs") granted in the Issuer's three prior fiscal years.

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February 10, 2026 Filed Feb 12, 2026 21:30 UTC
Dreyer ScottEVP & Chief Commercial Officer
GrantCommon Stock 19,023 $0.00 $0.00
Disclosure

SEC source: 0001746251-26-000002 · form4-02122026_040201.xml · nonDerivative · entry 1

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 122,636

F1 · shares: Reflects the grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock. One-third (33%) of the RSUs shall vest on February 10, 2027, with the balance of the RSUs vesting in equal annual installments over the following two-year period, subject to the Reporting Person's continued service with the Issuer. The RSUs will be settled on each applicable vesting date in shares of the Issuer's common stock.

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December 08, 2025 Filed Dec 10, 2025 21:32 UTC
Dreyer ScottEVP & Chief Commercial Officer
Exercise / conversionStock Option (Right to Purchase) · Derivative 17,600 $0.00 Strike: $15.90 $0.00
Disclosure

SEC source: 0001746251-25-000004 · form4-12102025_091236.xml · derivative · entry 4

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,600 shares

Expires 2029-01-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

F4 · derivative.exercise_date: The option is fully vested and exercisable.

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December 08, 2025 Filed Dec 10, 2025 21:32 UTC
Dreyer ScottEVP & Chief Commercial Officer
SaleCommon Stock 6,475 $48.66 $315,084.51
Disclosure

SEC source: 0001746251-25-000004 · form4-12102025_091236.xml · nonDerivative · entry 3

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 103,613

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

F3 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $48.215 to $49.08, inclusive.

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December 08, 2025 Filed Dec 10, 2025 21:32 UTC
Dreyer ScottEVP & Chief Commercial Officer
SaleCommon Stock 11,125 $47.89 $532,770.69
Disclosure

SEC source: 0001746251-25-000004 · form4-12102025_091236.xml · nonDerivative · entry 2

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 110,088

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

F2 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $47.212 to $48.20, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

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December 08, 2025 Filed Dec 10, 2025 21:32 UTC
Dreyer ScottEVP & Chief Commercial Officer
Exercise / conversionCommon Stock 17,600 $15.90 $279,840.00
Disclosure

SEC source: 0001746251-25-000004 · form4-12102025_091236.xml · nonDerivative · entry 1

Dreyer Scott · CIK 0001746251 · EVP & Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 121,213

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2025.

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December 05, 2025 Filed Dec 9, 2025 21:22 UTC SaleCommon Stock 3,650 $47.03 $171,673.37
Disclosure

SEC source: 0001825625-25-000004 · form4-12092025_091255.xml · nonDerivative · entry 1

Balice-Gordon Rita J. · CIK 0001825625 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,629

F1 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $47.0301 to $47.0901, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 12, 2025 Filed Nov 14, 2025 21:10 UTC Exercise / conversionStock Option (Right to Purchase) · Derivative 19,853 $0.00 Strike: $9.33 $0.00
Disclosure

SEC source: 0001560152-25-000004 · form4-11142025_091156.xml · derivative · entry 5

Fallon John A. · CIK 0001560152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 19,853 shares

Expires 2027-05-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option is fully vested and exercisable.

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November 12, 2025 Filed Nov 14, 2025 21:10 UTC Exercise / conversionStock Option (Right to Purchase) · Derivative 15,000 $0.00 Strike: $16.49 $0.00
Disclosure

SEC source: 0001560152-25-000004 · form4-11142025_091156.xml · derivative · entry 4

Fallon John A. · CIK 0001560152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2026-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option is fully vested and exercisable.

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November 12, 2025 Filed Nov 14, 2025 21:10 UTC SaleCommon Stock 34,853 $47.21 $1,645,535.60
Disclosure

SEC source: 0001560152-25-000004 · form4-11142025_091156.xml · nonDerivative · entry 3

Fallon John A. · CIK 0001560152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,634

F1 · price: The price reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $46.805 to $47.51, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 12, 2025 Filed Nov 14, 2025 21:10 UTC Exercise / conversionCommon Stock 19,853 $9.33 $185,228.49
Disclosure

SEC source: 0001560152-25-000004 · form4-11142025_091156.xml · nonDerivative · entry 2

Fallon John A. · CIK 0001560152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,487

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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November 12, 2025 Filed Nov 14, 2025 21:10 UTC Exercise / conversionCommon Stock 15,000 $16.49 $247,350.00
Disclosure

SEC source: 0001560152-25-000004 · form4-11142025_091156.xml · nonDerivative · entry 1

Fallon John A. · CIK 0001560152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,634

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.