BDSX

SEC source: 0001140361-21-040848 · form4.xml · derivative · entry 2

Kayyem Jon Faiz · CIK 0001366268 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,368

Underlying: Common Stock · 50,368 shares

Expires 2031-12-05

F3 · derivative.exercise_date: This option vests 40% on December 6, 2023, and the remaining 60% in 36 successive, equal monthly installments measured from December 6, 2023, generally subject to the reporting person's continued service on the Board through the applicable vesting date.

SEC source: 0001140361-21-040848 · form4.xml · derivative · entry 1

Kayyem Jon Faiz · CIK 0001366268 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,619

Underlying: Common Stock · 31,619 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: These restricted stock units will vest in full on December 6, 2022, generally subject to the reporting person's continued service on the Issuer's board of directors (the "Board") through the applicable vesting date, and have no expiration date.

F2 · derivative.expiration_date: These restricted stock units will vest in full on December 6, 2022, generally subject to the reporting person's continued service on the Issuer's board of directors (the "Board") through the applicable vesting date, and have no expiration date.

SEC source: 0001567619-21-021148 · doc1.xml · nonDerivative · entry 1

PATIENCE JOHN · CIK 0001021413 · Director · 10% owner · Chairman

10b5-1 filing: Not disclosed

Ownership: Indirect · By Patience Enterprises LP

Disclosed balance after: 1,940,367

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.74 to $6.38, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F1 · ownership.nature: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-021147 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 6,164,314

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.00 to $6.40, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001567619-21-021008 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 6,144,314

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.44 to $6.53, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001567619-21-020953 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 6,084,314

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.12 to $6.49, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001567619-21-020954 · doc1.xml · nonDerivative · entry 1

PATIENCE JOHN · CIK 0001021413 · Director · 10% owner · Chairman

10b5-1 filing: Not disclosed

Ownership: Indirect · By Patience Enterprises LP

Disclosed balance after: 1,930,367

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.14 to $6.50, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F1 · ownership.nature: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-020776 · doc1.xml · nonDerivative · entry 1

Hutton Scott · CIK 0001697361 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,762

F1 · price: The price reported in Column 4 is a weighted average price. These shares of Common Stock were purchased in multiple transactions at prices ranging from $6.23 to $6.57, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth herein.

F2 · balance_after: Includes 1,262 shares acquired under the BDSX stock purchase plan on August 31, 2021.

SEC source: 0001567619-21-020775 · doc1.xml · nonDerivative · entry 1

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,975

F1 · price: The price reported in Column 4 is a weighted average price. These shares of Common Stock were purchased in multiple transactions at prices ranging from $6.41 to $6.61, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth herein.

F2 · balance_after: Includes 1,262 shares acquired under the BDSX stock purchase plan on August 31, 2021.

SEC source: 0001567619-21-020812 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 6,055,953

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.23 to $6.64, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001567619-21-016210 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 6,035,953

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.295 to $8.00, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001567619-21-016211 · doc1.xml · nonDerivative · entry 1

PATIENCE JOHN · CIK 0001021413 · Director · 10% owner · Chairman

10b5-1 filing: Not disclosed

Ownership: Indirect · By Patience Enterprises LP

Disclosed balance after: 1,920,870

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.80 to $8.325, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F1 · ownership.nature: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-016112 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 5,985,953

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.59 to $7.50, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0000905148-21-000612 · form4.xml · nonDerivative · entry 1

PATIENCE JOHN · CIK 0001021413 · Director · 10% owner · Chairman

10b5-1 filing: Not disclosed

Ownership: Indirect · By Patience Enterprises LP

Disclosed balance after: 1,912,474

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.94 to $7.25, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F4 · balance_after: In the Form 4 filed by the Reporting Person on November 3, 2020, and each subsequent Form 4, the Amount of Securities Beneficially Owned in Table I was inadvertently overstated by 98 shares. This Form 4 corrects, in Table I, the Amount of Securities Beneficially Owned by the Reporting Person.

F1 · ownership.direct: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F1 · ownership.nature: The reporting person is the sole general partner of Patience Enterprises LP. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

SEC source: 0001567619-21-015962 · doc1.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Jack W. Schuler Living Trust

Disclosed balance after: 5,956,513

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.93 to $7.635, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F4 · balance_after: In the Form 4 filed by the Reporting Person on November 3, 2020, and each subsequent Form 4, the Amount of Securities Beneficially Owned in Table I was inadvertently overstated by 906 shares. This Form 4 corrects, in Table I, the Amount of Securities Beneficially Owned by the Reporting Person.

F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0000905148-21-000537 · form4.xml · derivative · entry 1

SCHULER JACK W · CIK 0001021412 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,385

Underlying: Common Stock · 34,385 shares

Expires 2031-06-28

F1 · derivative.exercise_date: This option will vest in full on March 31, 2022.

SEC source: 0000905148-21-000536 · form4.xml · derivative · entry 1

PATIENCE JOHN · CIK 0001021413 · Director · 10% owner · Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,385

Underlying: Common Stock · 34,385 shares

Expires 2031-06-28

F1 · derivative.exercise_date: This option will vest in full on March 31, 2022.

SEC source: 0000905148-21-000538 · form4.xml · derivative · entry 1

MASSARANY HANY · CIK 0001134554 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,789

Underlying: Common Stock · 25,789 shares

Expires 2031-06-28

F1 · derivative.exercise_date: This option will vest in full on March 31, 2022.

SEC source: 0000905148-21-000539 · form4.xml · derivative · entry 1

Watts Charles M · CIK 0001723751 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,385

Underlying: Common Stock · 34,385 shares

Expires 2031-06-28

F1 · derivative.exercise_date: This option will vest in full on March 31, 2022.

SEC source: 0000905148-21-000542 · form4.xml · derivative · entry 1

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

Underlying: Common Stock · 1,000 shares

Expires 2031-06-28

F1 · derivative.exercise_date: This option vests in a series of sixty (60) successive equal monthly installments measured from March 12, 2021, subject to the reporting person's continuous service through the applicable vesting date.

SEC source: 0000905148-21-000541 · form4.xml · derivative · entry 1

Strobeck Matthew · CIK 0001377832 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,044

Underlying: Common Stock · 20,044 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: These restricted stock units will vest in full on March 31, 2022 and have no expiration date.

F2 · derivative.expiration_date: These restricted stock units will vest in full on March 31, 2022 and have no expiration date.

SEC source: 0000905148-21-000540 · form4.xml · derivative · entry 1

Franchi Jean M. · CIK 0001653053 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,044

Underlying: Common Stock · 20,044 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: These restricted stock units will vest in full on March 31, 2022 and have no expiration date.

F2 · derivative.expiration_date: These restricted stock units will vest in full on March 31, 2022 and have no expiration date.

SEC source: 0001140361-21-011991 · form4.xml · derivative · entry 3

Georgantas Robert William III · CIK 0001827728 · Director · SVP, Rsrch & Trans'l Science

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,262

Underlying: Common Stock · 10,219 shares

Expires 2030-04-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: This Form 4 corrects the exercise price previously reported as $0.78 on the Form 3 filed on October 27, 2020.

F1 · derivative.exercise_date: This option vests 20% on January 1, 2021, and the remaining 80% in 48 successive, equal monthly installments measured from January 1, 2021.

SEC source: 0001140361-21-011991 · form4.xml · nonDerivative · entry 1

Georgantas Robert William III · CIK 0001827728 · Director · SVP, Rsrch & Trans'l Science

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,774

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000905148-21-000336 · form4.xml · derivative · entry 8

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,369

Underlying: Common Stock · 13,689 shares

Expires 2028-04-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests in 60 successive, equal monthly installments measured from January 1, 2018.

SEC source: 0000905148-21-000336 · form4.xml · derivative · entry 7

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,520

Underlying: Common Stock · 14,326 shares

Expires 2027-05-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option vests in 60 successive, equal monthly installments measured from January 1, 2017.

SEC source: 0000905148-21-000336 · form4.xml · derivative · entry 6

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,172 shares

Expires 2026-04-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000905148-21-000336 · form4.xml · derivative · entry 5

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,526 shares

Expires 2021-04-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option vested 40% on March 28, 2013, and the remaining 60% in 36 successive, equal monthly installments measured from March 28, 2013.

SEC source: 0000905148-21-000336 · form4.xml · nonDerivative · entry 4

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,713

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000905148-21-000336 · form4.xml · nonDerivative · entry 3

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,024

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000905148-21-000336 · form4.xml · nonDerivative · entry 2

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,698

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000905148-21-000336 · form4.xml · nonDerivative · entry 1

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,526

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001567619-22-006913 · doc1.xml · derivative · entry 1

Hutton Scott · CIK 0001697361 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,423

Underlying: Common Stock · 8,423 shares

Expires 2029-03-21

F1 · shares: On March 22, 2019, the Reporting Person was granted an option to purchase 25,269 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 8,423 shares underlying the option.

F2 · shares: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 8,423 shares underlying the option.

F1 · derivative.exercise_date: On March 22, 2019, the Reporting Person was granted an option to purchase 25,269 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 8,423 shares underlying the option.

F2 · derivative.exercise_date: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 8,423 shares underlying the option.

SEC source: 0001567619-22-006920 · doc1.xml · derivative · entry 1

O'Kane Kieran · CIK 0001828131 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,212

Underlying: Common Stock · 4,212 shares

Expires 2030-04-14

F1 · shares: On April 15, 2020, the Reporting Person was granted an option to purchase 8,423 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2020 and 2021 fiscal years.

F2 · shares: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 4,212 shares underlying the option.

F1 · derivative.exercise_date: On April 15, 2020, the Reporting Person was granted an option to purchase 8,423 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2020 and 2021 fiscal years.

F2 · derivative.exercise_date: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 4,212 shares underlying the option.

SEC source: 0001567619-22-006915 · doc1.xml · derivative · entry 1

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,615

Underlying: Common Stock · 5,615 shares

Expires 2029-03-21

F1 · shares: On March 22, 2019, the Reporting Person was granted an option to purchase 16,845 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 5,615 shares underlying the option.

F2 · shares: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 5,615 shares underlying the option.

F1 · derivative.exercise_date: On March 22, 2019, the Reporting Person was granted an option to purchase 16,845 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 5,615 shares underlying the option.

F2 · derivative.exercise_date: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 5,615 shares underlying the option.

SEC source: 0001567619-22-006911 · doc1.xml · derivative · entry 1

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,896

Underlying: Common Stock · 5,896 shares

Expires 2029-03-21

F1 · shares: On March 22, 2019, the Reporting Person was granted an option to purchase 17,688 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 5,896 shares underlying the option.

F2 · shares: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 5,896 shares underlying the option.

F1 · derivative.exercise_date: On March 22, 2019, the Reporting Person was granted an option to purchase 17,688 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2019, 2020 and 2021 fiscal years. The performance criteria was not met for fiscal year 2019, resulting in the cancellation of 5,896 shares underlying the option.

F2 · derivative.exercise_date: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 5,896 shares underlying the option.

SEC source: 0001567619-22-007219 · doc1.xml · derivative · entry 1

Georgantas Robert William III · CIK 0001827728 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,843

Underlying: Common Stock · 2,843 shares

Expires 2030-04-14

F1 · shares: On April 15, 2020, the Reporting Person was granted an option to purchase 5,685 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2020 and 2021 fiscal years.

F2 · shares: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 2,843 shares underlying the option.

F1 · derivative.exercise_date: On April 15, 2020, the Reporting Person was granted an option to purchase 5,685 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2020 and 2021 fiscal years.

F2 · derivative.exercise_date: On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 2,843 shares underlying the option.

SEC source: 0000905148-23-000509 · form4.xml · derivative · entry 2

Hutton Scott · CIK 0001697361 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 115,203

Underlying: Common Stock · 115,203 shares

Expires 2031-02-22

F2 · derivative.exercise_date: This option was fully vested as of the grant date.

SEC source: 0000905148-23-000509 · form4.xml · derivative · entry 1

Hutton Scott · CIK 0001697361 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 255,688

Underlying: Common Stock · 255,688 shares

Expires 2031-02-22

F1 · derivative.exercise_date: This option was scheduled to vest in a series of 60 successive, equal monthly installments measured from February 23, 2021.

SEC source: 0000905148-23-000512 · form4.xml · derivative · entry 2

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,155

Underlying: Common Stock · 5,155 shares

Expires 2031-02-22

F2 · derivative.exercise_date: This option was fully vested as of the grant date.

SEC source: 0000905148-23-000512 · form4.xml · derivative · entry 1

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,134

Underlying: Common Stock · 25,134 shares

Expires 2031-02-22

F1 · derivative.exercise_date: This option was scheduled to vest in a series of 60 successive, equal monthly installments measured from February 23, 2021.

SEC source: 0000905148-23-000511 · form4.xml · derivative · entry 2

O'Kane Kieran · CIK 0001828131 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,055

Underlying: Common Stock · 31,055 shares

Expires 2031-02-22

F2 · derivative.exercise_date: This option was fully vested as of the grant date.

SEC source: 0000905148-23-000511 · form4.xml · derivative · entry 1

O'Kane Kieran · CIK 0001828131 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,599

Underlying: Common Stock · 25,599 shares

Expires 2031-02-22

F1 · derivative.exercise_date: This option was scheduled to vest in a series of 60 successive, equal monthly installments measured from February 23, 2021.

SEC source: 0000905148-23-000510 · form4.xml · derivative · entry 2

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,524

Underlying: Common Stock · 71,524 shares

Expires 2031-02-22

F2 · derivative.exercise_date: This option was fully vested as of the grant date.

SEC source: 0000905148-23-000510 · form4.xml · derivative · entry 1

Cowie Robin Harper · CIK 0001827690 · CFO, Sec'y & Treasurer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 61,439

Underlying: Common Stock · 61,439 shares

Expires 2031-02-22

F1 · derivative.exercise_date: This option was scheduled to vest in a series of 60 successive, equal monthly installments measured from February 23, 2021.

SEC source: 0000905148-21-000049 · form4.xml · derivative · entry 1

Siurek Ryan H · CIK 0001476512 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2031-01-06

F1 · date: This option vests 40% on December 31, 2022, and the remaining 60% in 36 successive, equal monthly installments measured from December 31, 2022.

F1 · kind: This option vests 40% on December 31, 2022, and the remaining 60% in 36 successive, equal monthly installments measured from December 31, 2022.

F1 · derivative.exercise_date: This option vests 40% on December 31, 2022, and the remaining 60% in 36 successive, equal monthly installments measured from December 31, 2022.

SEC source: 0001140361-20-029017 · form4.xml · derivative · entry 18

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,258

Underlying: Common Stock · 4,327 shares

Expires 2030-04-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: This option vests in 60 successive, equal monthly installments measured from January 1, 2020.

SEC source: 0001140361-20-029017 · form4.xml · derivative · entry 17

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,655

Underlying: Common Stock · 10,984 shares

Expires 2028-12-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: This option vests twenty-one sixtieths (21/60ths) on October 1, 2020, the remaining balance vests in 39 successive, equal monthly installments measured from October 1, 2020.

SEC source: 0001140361-20-029017 · form4.xml · derivative · entry 16

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,773

Underlying: Common Stock · 12,285 shares

Expires 2028-04-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This option vests in 60 successive, equal monthly installments measured from January 1, 2018.

SEC source: 0001140361-20-029017 · form4.xml · derivative · entry 15

Pestano Gary Anthony · CIK 0001827711 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,640

Underlying: Common Stock · 13,206 shares

Expires 2027-05-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option vests in 60 successive, equal monthly installments measured from January 1, 2017.