BCRX

SEC source: 0001127602-22-028080 · form4.xml · nonDerivative · entry 1

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,015,230

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028078 · form4.xml · derivative · entry 2

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

Underlying: Common Stock · 8,500 shares

Expires 2032-12-19

F2 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028078 · form4.xml · nonDerivative · entry 1

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,653

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028076 · form4.xml · derivative · entry 2

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,500

Underlying: Common Stock · 158,500 shares

Expires 2032-12-19

F2 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028076 · form4.xml · nonDerivative · entry 1

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 245,610

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028074 · form4.xml · derivative · entry 2

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,500

Underlying: Common Stock · 158,500 shares

Expires 2032-12-19

F2 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-028074 · form4.xml · nonDerivative · entry 1

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 197,966

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-22-027894 · form4.xml · nonDerivative · entry 1

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 887,730

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022 to cover tax withholding obligations in connection with the vesting of 30,750 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.50 to $11.39. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-027887 · form4.xml · nonDerivative · entry 1

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 133,275

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 14, 2022 to cover tax withholding obligations in connection with the vesting of 11,000 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.50 to $11.33. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-027883 · form4.xml · nonDerivative · entry 1

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 163,966

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022 to cover tax withholding obligations in connection with the vesting of 18,750 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.50 to $11.35. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-027875 · form4.xml · nonDerivative · entry 1

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 211,610

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 14, 2022 to cover tax withholding obligations in connection with the vesting of 20,000 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.50 to $11.33. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-027870 · form4.xml · nonDerivative · entry 1

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,753

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 14, 2022 to cover tax withholding obligations in connection with the vesting of 1,462 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.54 to $11.40. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-027858 · form4.xml · nonDerivative · entry 1

Barnes Alane P · CIK 0001584348 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 198,770

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2022 to cover tax withholding obligations in connection with the vesting of 13,750 Restricted Stock Units. The sale occurred automatically to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $10.50 to $11.33. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-026832 · form4.xml · derivative · entry 8

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 82,656 shares

Expires 2023-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

SEC source: 0001127602-22-026832 · form4.xml · nonDerivative · entry 4

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 901,830

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

F3 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $12.69 to $12.92. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-026832 · form4.xml · nonDerivative · entry 3

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 984,486

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

SEC source: 0001127602-22-026834 · form4.xml · derivative · entry 3

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,600 shares

Expires 2023-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-22-026834 · form4.xml · nonDerivative · entry 2

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,198

F1 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $13.01 to $13.03. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-026834 · form4.xml · nonDerivative · entry 1

Jones Michael L · CIK 0001800060 · Exec. Director, Finance - PAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,798

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-22-026832 · form4.xml · derivative · entry 7

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,656

Underlying: Common Stock · 214,917 shares

Expires 2023-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

SEC source: 0001127602-22-026832 · form4.xml · nonDerivative · entry 2

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 901,830

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $12.75 to $13.45. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-026832 · form4.xml · nonDerivative · entry 1

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,116,747

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 10, 2021. The options were originally granted to the reporting person on January 1, 2013 and would have expired on January 1, 2023. The shares sold subsequent to the exercise of such options represent less than 10% of the reporting person's holdings of the issuer's securities.

SEC source: 0001127602-22-026830 · form4.xml · nonDerivative · entry 1

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,054

F1 · security: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-026828 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,191

F1 · security: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-026825 · form4.xml · nonDerivative · entry 1

LEVIN ALAN G · CIK 0001174452 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,714

F1 · security: Shares of Common Stock issued to the reporting person in lieu of quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-026823 · form4.xml · nonDerivative · entry 1

INGRAM ROBERT ALEXANDER · CIK 0001219890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,939

F1 · security: Shares of Common Stock issued to the reporting person in lieu of quarterly cash Board Member retainer of $20,000.

SEC source: 0001127602-22-025761 · form4.xml · derivative · entry 5

Babu Yarlagadda S · CIK 0001452635 · Chief Discovery Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 50,000 shares

Expires 2023-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Retention Employee Stock Option became exercisable in two equal annual installments, beginning on this date.

SEC source: 0001127602-22-025761 · form4.xml · derivative · entry 4

Babu Yarlagadda S · CIK 0001452635 · Chief Discovery Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 50,000 shares

Expires 2023-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Annual Employee Option Grant became exercisable in four equal annual installments, beginning on this date.

SEC source: 0001127602-22-025761 · form4.xml · nonDerivative · entry 3

Babu Yarlagadda S · CIK 0001452635 · Chief Discovery Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,541

F1 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $13.86 to $13.92. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-22-025761 · form4.xml · nonDerivative · entry 2

Babu Yarlagadda S · CIK 0001452635 · Chief Discovery Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 330,056

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-22-025761 · form4.xml · nonDerivative · entry 1

Babu Yarlagadda S · CIK 0001452635 · Chief Discovery Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 280,056

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-22-022018 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,770

F1 · security: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-022003 · form4.xml · nonDerivative · entry 1

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,633

F1 · security: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-022014 · form4.xml · nonDerivative · entry 1

LEVIN ALAN G · CIK 0001174452 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,872

F1 · security: Shares of Common Stock issued to the reporting person in lieu of quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-22-022009 · form4.xml · nonDerivative · entry 1

INGRAM ROBERT ALEXANDER · CIK 0001219890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,442

F1 · security: Shares of Common Stock issued to the reporting person in lieu of quarterly cash Board Member retainer of $20,000.

SEC source: 0001127602-22-017169 · form4.xml · derivative · entry 2

SANDERS MACHELLE · CIK 0001718020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017169 · form4.xml · nonDerivative · entry 1

SANDERS MACHELLE · CIK 0001718020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,866

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017167 · form4.xml · derivative · entry 2

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017167 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,366

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017165 · form4.xml · derivative · entry 2

INGRAM ROBERT ALEXANDER · CIK 0001219890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017165 · form4.xml · nonDerivative · entry 1

INGRAM ROBERT ALEXANDER · CIK 0001219890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,004

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017163 · form4.xml · derivative · entry 2

Hutson Nancy J · CIK 0001379222 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017163 · form4.xml · nonDerivative · entry 1

Hutson Nancy J · CIK 0001379222 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,939

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017160 · form4.xml · derivative · entry 2

McKee Amy E · CIK 0001883764 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017160 · form4.xml · nonDerivative · entry 1

McKee Amy E · CIK 0001883764 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,866

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017157 · form4.xml · derivative · entry 2

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017157 · form4.xml · nonDerivative · entry 1

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,229

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017153 · form4.xml · derivative · entry 2

ABERCROMBIE GEORGE B · CIK 0001485939 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-22-017153 · form4.xml · nonDerivative · entry 1

ABERCROMBIE GEORGE B · CIK 0001485939 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,866

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-22-017144 · form4.xml · derivative · entry 2

LEE KENNETH B JR · CIK 0001208570 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,022

Underlying: Common Stock · 30,022 shares

Expires 2032-06-07

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.