BCRX

SEC source: 0001171843-25-003914 · ownership.xml · nonDerivative · entry 1

Hutson Nancy J · CIK 0001379222 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,138

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001171843-25-003915 · ownership.xml · derivative · entry 2

LEVIN ALAN G · CIK 0001174452 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,181

Underlying: Common Stock · 27,181 shares

Expires 2035-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001171843-25-003915 · ownership.xml · nonDerivative · entry 1

LEVIN ALAN G · CIK 0001174452 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,271

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001171843-25-003913 · ownership.xml · derivative · entry 2

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,181

Underlying: Common Stock · 27,181 shares

Expires 2035-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001171843-25-003913 · ownership.xml · nonDerivative · entry 1

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,352

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001171843-25-003912 · ownership.xml · derivative · entry 3

Galson Steven K · CIK 0001495328 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,181

Underlying: Common Stock · 27,181 shares

Expires 2035-06-12

F3 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001171843-25-003912 · ownership.xml · nonDerivative · entry 1

Galson Steven K · CIK 0001495328 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,991

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001171843-25-003911 · ownership.xml · derivative · entry 2

Frank Steven · CIK 0001583886 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,181

Underlying: Common Stock · 27,181 shares

Expires 2035-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001171843-25-003911 · ownership.xml · nonDerivative · entry 1

Frank Steven · CIK 0001583886 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,699

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-25-016424 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,260

F1 · shares: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-25-016419 · form4.xml · nonDerivative · entry 1

Frank Steven · CIK 0001583886 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,199

F1 · shares: Shares of Common Stock issued to the reporting person in lieu of 100% of the prorated quarterly cash Board Member retainer of $3,585.

SEC source: 0001127602-25-013478 · form4.xml · derivative · entry 2

Frank Steven · CIK 0001583886 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,079

Underlying: Common Stock · 4,079 shares

Expires 2035-05-02

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

F3 · derivative.exercise_date: The option grant vests 1/36 per month over a 3-year period measured from the date of grant.

SEC source: 0001127602-25-013478 · form4.xml · nonDerivative · entry 1

Frank Steven · CIK 0001583886 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,866

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest in three equal annual installments beginning on the twelve-month anniversary of the date of grant.

SEC source: 0001127602-25-011136 · form4.xml · nonDerivative · entry 1

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 377,318

F1 · shares: Represents shares withheld by the issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the reporting person.

SEC source: 0001127602-25-007884 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,737

F1 · shares: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-24-029948 · form4.xml · nonDerivative · entry 5

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · By wife as co-trustee of the Samuel Stonehouse Irrevocable Trust

Disclosed balance after: 30,000

F3 · kind: On December 20, 2024, the Reporting Person gifted 10,000 shares held directly by him to each of the Samuel Stonehouse Irrevocable Trust and the Caroline Stonehouse Irrevocable Trust.

SEC source: 0001127602-24-029948 · form4.xml · nonDerivative · entry 4

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · By wife as co-trustee of the Caroline Stonehouse Irrevocable Trust

Disclosed balance after: 30,000

F3 · kind: On December 20, 2024, the Reporting Person gifted 10,000 shares held directly by him to each of the Samuel Stonehouse Irrevocable Trust and the Caroline Stonehouse Irrevocable Trust.

SEC source: 0001127602-24-029948 · form4.xml · nonDerivative · entry 3

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,429,109

F3 · kind: On December 20, 2024, the Reporting Person gifted 10,000 shares held directly by him to each of the Samuel Stonehouse Irrevocable Trust and the Caroline Stonehouse Irrevocable Trust.

SEC source: 0001127602-24-029971 · form4.xml · derivative · entry 3

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 260,950

Underlying: Common Stock · 260,950 shares

Expires 2034-12-19

F3 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029971 · form4.xml · nonDerivative · entry 2

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 423,546

F2 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029971 · form4.xml · nonDerivative · entry 1

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 426,007

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029965 · form4.xml · derivative · entry 3

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,100

Underlying: Common Stock · 250,100 shares

Expires 2034-12-19

F3 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029965 · form4.xml · nonDerivative · entry 2

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 377,867

F2 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029965 · form4.xml · nonDerivative · entry 1

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 380,328

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029969 · form4.xml · derivative · entry 3

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 260,950

Underlying: Common Stock · 260,950 shares

Expires 2034-12-19

F3 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029969 · form4.xml · nonDerivative · entry 2

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 384,843

F2 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029969 · form4.xml · nonDerivative · entry 1

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 390,939

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029952 · form4.xml · derivative · entry 3

Barnes Alane P · CIK 0001584348 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,100

Underlying: Common Stock · 250,100 shares

Expires 2034-12-19

F3 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029952 · form4.xml · nonDerivative · entry 2

Barnes Alane P · CIK 0001584348 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 412,729

F2 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029952 · form4.xml · nonDerivative · entry 1

Barnes Alane P · CIK 0001584348 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 415,190

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029948 · form4.xml · derivative · entry 6

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 750,250

Underlying: Common Stock · 750,250 shares

Expires 2034-12-19

F4 · derivative.exercise_date: Annual Employee Option Grant becomes exercisable at the rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029948 · form4.xml · nonDerivative · entry 2

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,449,109

F2 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029948 · form4.xml · nonDerivative · entry 1

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,463,119

F1 · shares: Annual award of Restricted Stock Units which will vest 25% on each of the first, second, third and fourth anniversaries of the date of grant.

SEC source: 0001127602-24-029602 · form4.xml · nonDerivative · entry 1

Gayer Charles K · CIK 0001800110 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,057

F1 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029592 · form4.xml · nonDerivative · entry 1

Stonehouse Jon P · CIK 0001385496 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,101,019

F1 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029582 · form4.xml · nonDerivative · entry 1

Barnes Alane P · CIK 0001584348 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 294,490

F1 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029573 · form4.xml · nonDerivative · entry 1

Doyle Anthony · CIK 0001808688 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 259,628

F1 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029566 · form4.xml · nonDerivative · entry 1

Thackray Helen M. · CIK 0001589725 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 264,989

F1 · shares: Represents shares withheld by the Issuer to satisfy required tax withholding obligations in connection with the vesting of previously granted Restricted Stock Units. This transaction does not represent a sale by the Reporting Person.

SEC source: 0001127602-24-029494 · form4.xml · nonDerivative · entry 1

Hutson Nancy J · CIK 0001379222 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 86,638

F1 · shares: These shares were sold pursuant to a plan adopted by the Reporting Person on June 18, 2024 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended, for the sole purpose of generating sufficient proceeds to cover the tax liability incurred in connection with the vesting of 16,745 restricted stock units. The sale occurred automatically and does not represent a discretionary transaction by the Reporting Person.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $7.510 to $7.565. The Reporting Person will provide to the Issuer, any security holder of the Issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-24-028290 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,084

F1 · shares: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-24-023304 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,334

F1 · shares: Shares of Common Stock issued to the reporting person in lieu of 50% of the quarterly cash Board Member retainer of $11,250.

SEC source: 0001127602-24-019215 · form4.xml · nonDerivative · entry 1

McKee Amy E · CIK 0001883764 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,831

F1 · shares: These shares were sold with the sole purpose of generating sufficient proceeds to cover the tax liability incurred in connection with the vesting of 16,745 Restricted Stock Units on June 13, 2024.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $6.25 to $6.42. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-24-018846 · form4.xml · nonDerivative · entry 1

SANDERS MACHELLE · CIK 0001718020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,742

F1 · shares: These shares were sold with the sole purpose of generating sufficient proceeds to cover the tax liability incurred in connection with the vesting of 16,745 Restricted Stock Units on June 13, 2024.

F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $5.99 to $6.01. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-24-018715 · form4.xml · nonDerivative · entry 2

HEGGIE THERESA · CIK 0001760020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,852

F2 · shares: These shares were sold with the sole purpose of generating sufficient proceeds to cover the tax liability incurred in connection with the vesting of 16,745 Restricted Stock Units on June 13, 2024.

F3 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $6.08 to $6.15. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001127602-24-018737 · form4.xml · derivative · entry 2

SANDERS MACHELLE · CIK 0001718020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,933

Underlying: Common Stock · 49,933 shares

Expires 2034-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-24-018737 · form4.xml · nonDerivative · entry 1

SANDERS MACHELLE · CIK 0001718020 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,431

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-24-018733 · form4.xml · derivative · entry 2

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,933

Underlying: Common Stock · 49,933 shares

Expires 2034-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-24-018733 · form4.xml · nonDerivative · entry 1

MILANO VINCENT · CIK 0001187159 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,687

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.

SEC source: 0001127602-24-018728 · form4.xml · derivative · entry 2

McKee Amy E · CIK 0001883764 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,933

Underlying: Common Stock · 49,933 shares

Expires 2034-06-12

F2 · security: Automatic non-employee director grant of stock options pursuant to the Director Compensation Policy.

SEC source: 0001127602-24-018728 · form4.xml · nonDerivative · entry 1

McKee Amy E · CIK 0001883764 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,431

F1 · shares: Automatic non-employee director grant of Restricted Stock Units pursuant to the BioCryst Pharmaceuticals, Inc. Non-Employee Director Compensation Policy, as amended (the "Director Compensation Policy"), which will vest on the first anniversary of the date of grant.