BCAB

SEC source: 0001193125-26-380486 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,346

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-26-380482 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,035

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-26-380479 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,476

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP.

SEC source: 0001193125-26-259689 · ownership.xml · nonDerivative · entry 2

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,840

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-259702 · ownership.xml · nonDerivative · entry 2

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,294

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-259699 · ownership.xml · nonDerivative · entry 2

Vasquez Christian · CIK 0001835732 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,347

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-259702 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,553

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-104134 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,659,603

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 11, 2027, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-259689 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,614

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-259699 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,429

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Effective on April 6, 2026, the Issuer effected a 50-for-1 share consolidation of its common stock (the "Share Consolidation"). The amount of securities reported on this Form 4 has been adjusted to reflect the Share Consolidation.

SEC source: 0001193125-26-104136 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 598,705

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 10, 2027, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-104132 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 530,196

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 10, 2027, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February, subject to the reporting person's continued service through the applicable vesting date.

SEC source: 0001193125-26-085966 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 358,705

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-26-085968 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Former Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 343,421

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-26-085971 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,229,603

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-26-085970 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 290,196

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-25-304173 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 361,845

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-25-304178 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 346,150

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP.

SEC source: 0001193125-25-304171 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,237,331

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0001193125-25-304170 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 291,998

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP.

SEC source: 0000950170-25-112615 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 364,574

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-112614 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 338,521

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-112618 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,243,678

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-112616 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 283,564

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-088063 · ownership.xml · nonDerivative · entry 1

STEINMAN LAWRENCE · CIK 0001132679 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,459

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-088061 · ownership.xml · nonDerivative · entry 1

MCBRINN SYLVIA · CIK 0001284666 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,125

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-088062 · ownership.xml · nonDerivative · entry 1

GRAY MARY ANN · CIK 0001261974 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,397

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-088060 · ownership.xml · nonDerivative · entry 1

Smith Scott Andrew · CIK 0001614975 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 321,550

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-088064 · ownership.xml · nonDerivative · entry 1

Williams Eddie · CIK 0001725276 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,200

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-088065 · ownership.xml · nonDerivative · entry 1

Moran Susan · CIK 0001835225 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,307

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 18, 2026, or (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-25-080990 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 367,303

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-080991 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 340,892

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP Plan.

SEC source: 0000950170-25-080994 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,250,025

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-080980 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 285,130

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP Plan.

SEC source: 0000950170-25-038746 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,256,372

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 11, 2026, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February so long as the reporting person remains a service provider.

SEC source: 0000950170-25-038741 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 370,032

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 11, 2026, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February so long as the reporting person remains a service provider.

SEC source: 0000950170-25-038745 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 333,263

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 11, 2026, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February so long as the reporting person remains a service provider.

SEC source: 0000950170-25-038748 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 276,696

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 25% of the total number of shares on March 11, 2026, and thereafter, 6.25% of the total number of shares subject to the RSU shall vest on the last day of each May, August, November and February so long as the reporting person remains a service provider.

SEC source: 0000950170-25-025969 · ownership.xml · nonDerivative · entry 1

SHORT JAY M PHD · CIK 0001205375 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,825,372

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-025968 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,032

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-25-025967 · ownership.xml · nonDerivative · entry 1

WALDRON RICHARD A · CIK 0001226961 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 233,263

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP Plan.

SEC source: 0000950170-25-025962 · ownership.xml · nonDerivative · entry 1

Vasquez Christian · CIK 0001835732 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,696

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

F2 · balance_after: Includes shares purchased under the Issuer's ESPP Plan.

SEC source: 0000950170-24-102924 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 207,562

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-102925 · ownership.xml · nonDerivative · entry 1

Smith Scott Andrew · CIK 0001614975 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 298,050

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-089419 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 208,134

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-089427 · ownership.xml · nonDerivative · entry 1

Smith Scott Andrew · CIK 0001614975 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,231

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-079915 · ownership.xml · nonDerivative · entry 1

Sievers Eric · CIK 0001835116 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 208,706

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-079916 · ownership.xml · nonDerivative · entry 1

Smith Scott Andrew · CIK 0001614975 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 302,412

F1 · kind: This transaction is not a sale of shares by the Reporting Person. Instead, this represents shares that have been withheld by the Issuer to satisfy its income tax and withholding and remittance obligations in connection with the vesting and net settlement of previously reported restricted stock units.

SEC source: 0000950170-24-073675 · ownership.xml · nonDerivative · entry 1

STEINMAN LAWRENCE · CIK 0001132679 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,959

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 13, 2025, and (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.

SEC source: 0000950170-24-073681 · ownership.xml · nonDerivative · entry 1

MCBRINN SYLVIA · CIK 0001284666 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,625

F1 · shares: Represents shares of Common Stock underlying a time-based restricted stock unit award ("RSU"). The RSU will vest as to 100% of the total number of shares on the earlier of (i) June 13, 2025, and (ii) the next Company annual meeting of stockholders, subject to the reporting person's continued service through the vesting date.