Last 12 months
Inside the activity.
11 purchase rows · 2 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 3 | 0 |
| Mar 2026 | 3 | 0 |
| Apr 2026 | 0 | 0 |
| May 2026 | 2 | 0 |
| Jun 2026 | 3 | 0 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 0 | 1 |
| Sep 2026 | 0 | 1 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| September 10, 2026 Filed Sep 11, 2026 20:26 UTC |
Robertson Stephen P.Chief Legal Officer
|
SaleCommon Stock | 11,939 | $15.95 | $190,427.05 |
DisclosureSEC source: 0001600620-26-000068 · wk-form4_1789158362.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · Chief Legal Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 588,848 F1 · shares: Represents the number of shares automatically sold to cover tax withholding obligations in connection with the vesting of Performance Stock Units (PSUs) related to the February 28, 2025 performance award. F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.95 to $15.96, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. Read SEC document |
| August 21, 2026 Filed Aug 26, 2026 01:29 UTC |
Robertson Stephen P.Chief Legal Officer
|
SaleCommon Stock | 20,975 | $16.97 | $355,945.75 |
DisclosureSEC source: 0001837798-26-000013 · wk-form4_1787707766.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · Chief Legal Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 600,787 F1 · shares: Represents the number of shares automatically sold to cover tax withholding obligations in connection with the vesting of Performance Stock Units (PSUs) related to the February 28, 2025 performance award. F2 · price: The price in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.96 to $17.04, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. F3 · balance_after: Includes 360 common shares that were acquired on May 29, 2026 by the reporting person pursuant to the Issuer's 2021 Employee Share Purchase Plan. Read SEC document |
| June 04, 2026 Filed Jun 8, 2026 20:12 UTC |
Goetz KathleenDirector
|
GrantDirector Stock Option (right to buy) · Derivative | 23,931 | $0.00 Strike: $15.67 | $0.00 |
DisclosureSEC source: 0001896369-26-000002 · wk-form4_1780949524.xml · derivative · entry 1 Goetz Kathleen · CIK 0001896369 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 23,931 Underlying: Common Shares · 23,931 shares Expires 2036-06-04 F1 · derivative.exercise_date: The options shall vest one year from date of grant. Read SEC document |
| June 04, 2026 Filed Jun 8, 2026 20:08 UTC |
Bailey Jeffrey AllenDirector
|
GrantDirector Stock Option (right to buy) · Derivative | 23,931 | $0.00 Strike: $15.67 | $0.00 |
DisclosureSEC source: 0001500210-26-000002 · wk-form4_1780949328.xml · derivative · entry 1 Bailey Jeffrey Allen · CIK 0001500210 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 23,931 Underlying: Common Shares · 23,931 shares Expires 2036-06-04 F1 · derivative.exercise_date: The options shall vest one year from date of grant. Read SEC document |
| June 04, 2026 Filed Jun 8, 2026 20:10 UTC |
Nova Tina SusanDirector
|
GrantDirector Stock Option (right to buy) · Derivative | 23,931 | $0.00 Strike: $15.67 | $0.00 |
DisclosureSEC source: 0001302605-26-000002 · wk-form4_1780949446.xml · derivative · entry 1 Nova Tina Susan · CIK 0001302605 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 23,931 Underlying: Common Shares · 23,931 shares Expires 2036-06-04 F1 · derivative.exercise_date: The options shall vest one year from date of grant. Read SEC document |
| June 04, 2026 Filed Jun 8, 2026 20:14 UTC |
Johnson Craig ADirector
|
GrantDirector Stock Option (right to buy) · Derivative | 23,931 | $0.00 Strike: $15.67 | $0.00 |
DisclosureSEC source: 0001370348-26-000002 · wk-form4_1780949641.xml · derivative · entry 1 Johnson Craig A · CIK 0001370348 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 23,931 Underlying: Common Shares · 23,931 shares Expires 2036-06-04 F1 · derivative.exercise_date: The options shall vest one year from date of grant. Read SEC document |
| June 02, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
OtherShort Put Options (potential obligation to buy) · Derivative | 10,000 | $1.65 Strike: $15.00 | $16,500.00 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · derivative · entry 6 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 10,000 Underlying: Common Shares · 1,000,000 shares Expires 2027-01-15 F7 · derivative.exercise_date: Each put option is exercisable only at the option of the counterparty through the expiration date of the put option. F8 · balance_after: Securities are beneficially held by TCP III and TCP IV. The Funds sold 10,000 put options on June 2, 2026. Pursuant to the put option contracts, the Funds have the potential obligation to acquire 1,000,000 common shares of the Issuer at $15 expiring on January 15, 2027. F8 · ownership.nature: Securities are beneficially held by TCP III and TCP IV. The Funds sold 10,000 put options on June 2, 2026. Pursuant to the put option contracts, the Funds have the potential obligation to acquire 1,000,000 common shares of the Issuer at $15 expiring on January 15, 2027. Read SEC document |
| June 02, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
PurchaseCommon Shares | 206,005 | $15.28 | $3,147,756.40 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · nonDerivative · entry 5 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 13,044,106 F6 · price: These shares were purchased in multiple transactions ranging from $15.00 to $15.40. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 7,205,442 shares, Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares, Tang Capital Partners III, Inc. ("TCP III") beneficially owns 324,814 shares, and Tang Capital Partners IV, Inc. ("TCP IV") beneficially owns 274,811 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Kevin Tang is the sole director and Chief Executive Officer of TCP III and TCP IV, which are indirectly wholly owned by TCP. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP, TCPI, TCP III and TCP IV (collectively, the "Funds"). Read SEC document |
| June 01, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
PurchaseCommon Shares | 99 | $15.34 | $1,518.66 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · nonDerivative · entry 4 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,838,101 F5 · price: These shares were purchased at $15.34. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 7,205,442 shares, Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares, Tang Capital Partners III, Inc. ("TCP III") beneficially owns 324,814 shares, and Tang Capital Partners IV, Inc. ("TCP IV") beneficially owns 274,811 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Kevin Tang is the sole director and Chief Executive Officer of TCP III and TCP IV, which are indirectly wholly owned by TCP. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP, TCPI, TCP III and TCP IV (collectively, the "Funds"). Read SEC document |
| June 01, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
PurchaseCommon Shares | 343,521 | $15.28 | $5,249,000.88 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · nonDerivative · entry 3 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,838,002 F4 · price: These shares were purchased in multiple transactions ranging from $14.97 to $15.50. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 7,205,442 shares, Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares, Tang Capital Partners III, Inc. ("TCP III") beneficially owns 324,814 shares, and Tang Capital Partners IV, Inc. ("TCP IV") beneficially owns 274,811 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Kevin Tang is the sole director and Chief Executive Officer of TCP III and TCP IV, which are indirectly wholly owned by TCP. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP, TCPI, TCP III and TCP IV (collectively, the "Funds"). Read SEC document |
| May 29, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
PurchaseCommon Shares | 262,682 | $15.31 | $4,021,661.42 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · nonDerivative · entry 2 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,494,481 F3 · price: These shares were purchased in multiple transactions ranging from $15.05 to $15.37. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 7,205,442 shares, Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares, Tang Capital Partners III, Inc. ("TCP III") beneficially owns 324,814 shares, and Tang Capital Partners IV, Inc. ("TCP IV") beneficially owns 274,811 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Kevin Tang is the sole director and Chief Executive Officer of TCP III and TCP IV, which are indirectly wholly owned by TCP. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP, TCPI, TCP III and TCP IV (collectively, the "Funds"). Read SEC document |
| May 29, 2026 Filed Jun 3, 2026 01:54 UTC |
TANG KEVINDirector · Chief Executive Officer · 10% owner
TANG CAPITAL MANAGEMENT LLC10% owner
|
PurchaseCommon Shares | 2,299 | $15.35 | $35,289.65 |
DisclosureSEC source: 0001178579-26-000004 · form4-06032026_010631.xml · nonDerivative · entry 1 TANG KEVIN · CIK 0001178579 · Director · Chief Executive Officer · 10% owner TANG CAPITAL MANAGEMENT LLC · CIK 0001232621 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,231,799 F1 · price: The prices reported are weighted-average prices. These shares were purchased in multiple transactions at prices ranging from $15.33 to $15.38. The Reporting Persons undertake to provide the Issuer, any security holder of the Issuer or the SEC staff, upon request, all information regarding the number of shares purchased at each price within the ranges set forth in Footnotes 1 and 3 through 6. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 7,205,442 shares, Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares, Tang Capital Partners III, Inc. ("TCP III") beneficially owns 324,814 shares, and Tang Capital Partners IV, Inc. ("TCP IV") beneficially owns 274,811 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Kevin Tang is the sole director and Chief Executive Officer of TCP III and TCP IV, which are indirectly wholly owned by TCP. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP, TCPI, TCP III and TCP IV (collectively, the "Funds"). Read SEC document |
| May 18, 2026 Filed May 20, 2026 21:05 UTC |
Robertson Stephen P.Chief Legal Officer
|
GrantCommon Stock | 115,541 | $0.00 | $0.00 |
DisclosureSEC source: 0001837798-26-000005 · wk-form4_1779311116.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · Chief Legal Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 621,402 F1 · shares: Each performance stock unit ("PSU") represents a contingent right to receive one common share of the Issuer. 115,541 PSUs vest in two tranches at the three and five year anniversary date of grant if the Issuer's common shares achieve target prices that represent significant increases from the share price on date of grant before the respective vesting date. Read SEC document |
| May 18, 2026 Filed May 20, 2026 21:04 UTC |
Hearne Michael SChief Financial Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 70,230 | $0.00 Strike: $15.28 | $0.00 |
DisclosureSEC source: 0001759910-26-000004 · wk-form4_1779311085.xml · derivative · entry 2 Hearne Michael S · CIK 0001759910 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 70,230 Underlying: Common Stock · 70,230 shares Expires 2036-05-18 F2 · derivative.exercise_date: 33% vest on the 1-year anniversary of the grant date, and the remaining 67% vest equally in monthly installments over the following 2 years. Read SEC document |
| May 18, 2026 Filed May 20, 2026 21:04 UTC |
Hearne Michael SChief Financial Officer
|
GrantCommon Stock | 116,144 | $0.00 | $0.00 |
DisclosureSEC source: 0001759910-26-000004 · wk-form4_1779311085.xml · nonDerivative · entry 1 Hearne Michael S · CIK 0001759910 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 116,144 F1 · shares: Each performance stock unit ("PSU") represents a contingent right to receive one common share of the Issuer. 46,820 PSUs vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. 69,324 PSUs vest in two tranches at the three and five year anniversary date of grant if the Issuer's common shares achieve target prices that represent significant increases from the share price on date of grant before the respective vesting date. Read SEC document |
| May 18, 2026 Filed May 20, 2026 21:03 UTC |
Cole RyanChief Operating Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 70,230 | $0.00 Strike: $15.28 | $0.00 |
DisclosureSEC source: 0002126966-26-000003 · wk-form4_1779311027.xml · derivative · entry 2 Cole Ryan · CIK 0002126966 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 70,230 Underlying: Common Stock · 70,230 shares Expires 2036-05-18 F2 · derivative.exercise_date: 33% vest on the 1-year anniversary of the grant date, and the remaining 67% vest equally in monthly installments over the following 2 years. Read SEC document |
| May 18, 2026 Filed May 20, 2026 21:03 UTC |
Cole RyanChief Operating Officer
|
GrantCommon Stock | 116,144 | $0.00 | $0.00 |
DisclosureSEC source: 0002126966-26-000003 · wk-form4_1779311027.xml · nonDerivative · entry 1 Cole Ryan · CIK 0002126966 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 116,144 F1 · shares: Each performance stock unit ("PSU") represents a contingent right to receive one common share of the Issuer. 46,820 PSUs vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. 69,324 PSUs vest in two tranches at the three and five year anniversary date of grant if the Issuer's common shares achieve target prices that represent significant increases from the share price on date of grant before the respective vesting date. Read SEC document |
| March 06, 2026 Filed Mar 10, 2026 20:25 UTC |
Keenan GregSVP, Chief Medical Officer
|
Tax withholdingCommon Stock | 8,069 | $14.32 | $115,548.08 |
DisclosureSEC source: 0001600620-26-000024 · wk-form4_1773174347.xml · nonDerivative · entry 1 Keenan Greg · CIK 0002044006 · SVP, Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 154,449 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| March 03, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 184,208 | $14.22 | $2,619,437.76 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 6 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,229,500 F7 · price: These shares were purchased in multiple transactions ranging from $13.97 to $14.39. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 115,792 | $14.21 | $1,645,404.32 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 5 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 12,045,292 F6 · price: These shares were purchased in multiple transactions ranging from $14.14 to $14.33. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 83,561 | $14.33 | $1,197,429.13 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 4 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 11,929,500 F5 · price: These shares were purchased in multiple transactions ranging from $14.04 to $14.50. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 21:13 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
Tax withholdingCommon Stock | 100,890 | $14.21 | $1,433,646.90 |
DisclosureSEC source: 0001600620-26-000021 · wk-form4_1772572423.xml · nonDerivative · entry 2 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,840,379 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 21:14 UTC |
Miller Joseph MChief Financial Officer
|
Tax withholdingCommon Stock | 37,511 | $14.21 | $533,031.31 |
DisclosureSEC source: 0001600620-26-000023 · wk-form4_1772572473.xml · nonDerivative · entry 2 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 576,421 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 21:14 UTC |
Donley Matthew MaxwellChief Operating Officer
|
Tax withholdingCommon Stock | 40,761 | $14.21 | $579,213.81 |
DisclosureSEC source: 0001600620-26-000022 · wk-form4_1772572450.xml · nonDerivative · entry 2 Donley Matthew Maxwell · CIK 0001636642 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 680,299 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| March 02, 2026 Filed Mar 3, 2026 21:12 UTC |
Robertson Stephen P.EVP, General Counsel
|
Tax withholdingCommon Stock | 36,525 | $14.21 | $519,020.25 |
DisclosureSEC source: 0001600620-26-000019 · wk-form4_1772572374.xml · nonDerivative · entry 2 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 505,861 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 1,600 | $14.38 | $23,008.00 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 3 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 11,845,939 F4 · price: These shares were purchased in multiple transactions ranging from $14.35 to $14.61. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 214,839 | $14.12 | $3,033,526.68 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 2 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 11,844,339 F3 · price: These shares were purchased in multiple transactions ranging from $14.00 to $14.18. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 22:35 UTC |
TANG KEVINDirector
|
PurchaseCommon Shares | 300,000 | $13.90 | $4,170,000.00 |
DisclosureSEC source: 0001178579-26-000001 · form4-03032026_100309.xml · nonDerivative · entry 1 TANG KEVIN · CIK 0001178579 · Director 10b5-1 filing: No plan indicated Ownership: Indirect · By LP Disclosed balance after: 11,629,500 F1 · price: The prices reported are weighted-average prices. These shares were purchased in multiple transactions at prices ranging from $13.51 to $14.23. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer or the SEC staff, upon request, all information regarding the number of shares purchased at each price within the ranges set forth in Footnotes 1 and 3 through 7. F2 · ownership.nature: Tang Capital Partners, LP ("TCP") beneficially owns 6,990,461 shares and Tang Capital Partners International, LP ("TCPI") beneficially owns 5,239,039 shares. Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP and TCPI. Mr. Tang has a pecuniary interest in the shares beneficially held by TCP and TCPI. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:13 UTC |
Keenan GregSVP, Chief Medical Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 67,870 | $0.00 Strike: $13.97 | $0.00 |
DisclosureSEC source: 0001600620-26-000020 · wk-form4_1772572400.xml · derivative · entry 2 Keenan Greg · CIK 0002044006 · SVP, Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 67,870 Underlying: Common Stock · 67,870 shares Expires 2036-02-27 F2 · derivative.exercise_date: One-third of the shares subject to the option vests twelve months from the grant date, and the remainder vests in twenty-four equal monthly installments thereafter. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:13 UTC |
Keenan GregSVP, Chief Medical Officer
|
GrantCommon Stock | 40,586 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000020 · wk-form4_1772572400.xml · nonDerivative · entry 1 Keenan Greg · CIK 0002044006 · SVP, Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 162,518 F1 · shares: Each performance right represents a contingent right to receive one common share of the Issuer. The performance rights vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:13 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 328,424 | $0.00 Strike: $13.97 | $0.00 |
DisclosureSEC source: 0001600620-26-000021 · wk-form4_1772572423.xml · derivative · entry 3 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 328,424 Underlying: Common Stock · 328,424 shares Expires 2036-02-27 F3 · derivative.exercise_date: One-third of the shares subject to the option vests twelve months from the grant date, and the remainder vests in twenty-four equal monthly installments thereafter. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:13 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
GrantCommon Stock | 196,403 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000021 · wk-form4_1772572423.xml · nonDerivative · entry 1 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,941,269 F1 · shares: Each performance right represents a contingent right to receive one common share of the Issuer. The performance rights vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:14 UTC |
Miller Joseph MChief Financial Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 95,700 | $0.00 Strike: $13.97 | $0.00 |
DisclosureSEC source: 0001600620-26-000023 · wk-form4_1772572473.xml · derivative · entry 3 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 95,700 Underlying: Common Stock · 95,700 shares Expires 2036-02-27 F3 · derivative.exercise_date: One-third of the shares subject to the option vests twelve months from the grant date, and the remainder vests in twenty-four equal monthly installments thereafter. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:14 UTC |
Miller Joseph MChief Financial Officer
|
GrantCommon Stock | 57,229 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000023 · wk-form4_1772572473.xml · nonDerivative · entry 1 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 613,932 F1 · shares: Each performance right represents a contingent right to receive one common share of the Issuer. The performance rights vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:14 UTC |
Donley Matthew MaxwellChief Operating Officer
|
GrantEmployee Stock Option (right to buy) · Derivative | 97,256 | $0.00 Strike: $13.97 | $0.00 |
DisclosureSEC source: 0001600620-26-000022 · wk-form4_1772572450.xml · derivative · entry 3 Donley Matthew Maxwell · CIK 0001636642 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 97,256 Underlying: Common Stock · 97,256 shares Expires 2036-02-27 F3 · derivative.exercise_date: One-third of the shares subject to the option vests twelve months from the grant date, and the remainder vests in twenty-four equal monthly installments thereafter. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:14 UTC |
Donley Matthew MaxwellChief Operating Officer
|
GrantCommon Stock | 58,160 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000022 · wk-form4_1772572450.xml · nonDerivative · entry 1 Donley Matthew Maxwell · CIK 0001636642 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 721,060 F1 · shares: Each performance right represents a contingent right to receive one common share of the Issuer. The performance rights vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:12 UTC |
Robertson Stephen P.EVP, General Counsel
|
GrantEmployee Stock Option (right to buy) · Derivative | 98,813 | $0.00 Strike: $13.97 | $0.00 |
DisclosureSEC source: 0001600620-26-000019 · wk-form4_1772572374.xml · derivative · entry 3 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 98,813 Underlying: Common Stock · 98,813 shares Expires 2036-02-27 F3 · derivative.exercise_date: One-third of the shares subject to the option vests twelve months from the grant date, and the remainder vests in twenty-four equal monthly installments thereafter. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:12 UTC |
Robertson Stephen P.EVP, General Counsel
|
GrantCommon Stock | 59,090 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000019 · wk-form4_1772572374.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 542,386 F1 · shares: Each performance right represents a contingent right to receive one common share of the Issuer. The performance rights vest in four tranches upon the Issuer's common shares achieving four progressively higher target prices, with respective one year retention periods per tranche achievement. Read SEC document |
| February 20, 2026 Filed Feb 23, 2026 21:07 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
Tax withholdingCommon Stock | 100,171 | $14.40 | $1,442,462.40 |
DisclosureSEC source: 0001363683-26-000002 · wk-form4_1771880820.xml · nonDerivative · entry 1 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,744,866 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| February 20, 2026 Filed Feb 23, 2026 21:08 UTC |
Donley Matthew MaxwellChief Operating Officer
|
Tax withholdingCommon Stock | 32,901 | $14.40 | $473,774.40 |
DisclosureSEC source: 0001636642-26-000002 · wk-form4_1771880882.xml · nonDerivative · entry 1 Donley Matthew Maxwell · CIK 0001636642 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 662,900 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| February 20, 2026 Filed Feb 23, 2026 21:05 UTC |
Miller Joseph MChief Financial Officer
|
Tax withholdingCommon Stock | 32,424 | $14.40 | $466,905.60 |
DisclosureSEC source: 0001746372-26-000002 · wk-form4_1771880754.xml · nonDerivative · entry 1 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 556,703 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| February 20, 2026 Filed Feb 23, 2026 21:04 UTC |
Robertson Stephen P.EVP, General Counsel
|
Tax withholdingCommon Stock | 34,638 | $14.40 | $498,787.20 |
DisclosureSEC source: 0001837798-26-000002 · wk-form4_1771880670.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 483,296 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| February 02, 2026 Filed Feb 3, 2026 21:49 UTC |
Keenan GregSVP, Chief Medical Officer
|
Tax withholdingCommon Stock | 11,552 | $14.53 | $167,850.56 |
DisclosureSEC source: 0002044006-26-000002 · wk-form4_1770155355.xml · nonDerivative · entry 1 Keenan Greg · CIK 0002044006 · SVP, Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 121,932 F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:10 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
Tax withholdingCommon Stock | 113,169 | $15.95 | $1,805,045.55 |
DisclosureSEC source: 0001600620-26-000002 · wk-form4_1767647395.xml · nonDerivative · entry 2 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,845,037 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of performance awards. F3 · balance_after: Includes common shares acquired by the reporting person pursuant to the Issuer's 2021 Employee Share Purchase Plan as follows: 2,257 common shares were acquired on May 30, 2025 and 1,620 common shares were acquired on November 28, 2025. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:10 UTC |
Greenleaf PeterDirector · Chief Executive Officer
|
GrantCommon Stock | 165,384 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000002 · wk-form4_1767647395.xml · nonDerivative · entry 1 Greenleaf Peter · CIK 0001363683 · Director · Chief Executive Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,954,329 F1 · shares: Represents the number of shares earned upon certification of performance for a performance award payable solely in common shares of the Issuer that vest in two (2) equal annual installments on December 31, 2025 and December 31, 2026. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:13 UTC |
Robertson Stephen P.EVP, General Counsel
|
Tax withholdingCommon Stock | 40,385 | $15.95 | $644,140.75 |
DisclosureSEC source: 0001600620-26-000005 · wk-form4_1767647607.xml · nonDerivative · entry 2 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 517,934 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of performance awards. F3 · balance_after: Includes common shares acquired by the reporting person pursuant to the Issuer's 2021 Employee Share Purchase Plan as follows: 531 common shares were acquired on May 30, 2025 and 354 common shares were acquired on November 28, 2025. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:13 UTC |
Robertson Stephen P.EVP, General Counsel
|
GrantCommon Stock | 48,558 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000005 · wk-form4_1767647607.xml · nonDerivative · entry 1 Robertson Stephen P. · CIK 0001837798 · EVP, General Counsel 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 557,434 F1 · shares: Represents the number of shares earned upon certification of performance for a performance award payable solely in common shares of the Issuer that vest in two (2) equal annual installments on December 31, 2025 and December 31, 2026. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:11 UTC |
Miller Joseph MChief Financial Officer
|
Tax withholdingCommon Stock | 40,161 | $15.95 | $640,567.95 |
DisclosureSEC source: 0001600620-26-000003 · wk-form4_1767647470.xml · nonDerivative · entry 2 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 589,127 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of performance awards. F3 · balance_after: Includes common shares acquired by the reporting person pursuant to the Issuer's 2021 Employee Share Purchase Plan as follows: 1,721 common shares were acquired on May 30, 2025 and 1,168 common shares were acquired on November 28, 2025. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:11 UTC |
Miller Joseph MChief Financial Officer
|
GrantCommon Stock | 49,038 | $0.00 | $0.00 |
DisclosureSEC source: 0001600620-26-000003 · wk-form4_1767647470.xml · nonDerivative · entry 1 Miller Joseph M · CIK 0001746372 · Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 626,399 F1 · shares: Represents the number of shares earned upon certification of performance for a performance award payable solely in common shares of the Issuer that vest in two (2) equal annual installments on December 31, 2025 and December 31, 2026. Read SEC document |
| January 02, 2026 Filed Jan 5, 2026 21:12 UTC |
Donley Matthew MaxwellChief Operating Officer
|
Tax withholdingCommon Stock | 42,787 | $15.95 | $682,452.65 |
DisclosureSEC source: 0001600620-26-000004 · wk-form4_1767647524.xml · nonDerivative · entry 2 Donley Matthew Maxwell · CIK 0001636642 · Chief Operating Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 695,801 F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of performance awards. F3 · balance_after: Includes common shares acquired by the reporting person pursuant to the Issuer's 2021 Employee Share Purchase Plan as follows: 2,500 common shares were acquired on May 30, 2025 and 1,457 common shares were acquired on November 28, 2025. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.