Last 12 months
Inside the activity.
0 purchase rows · 5 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 4 |
| Apr 2026 | 0 | 0 |
| May 2026 | 0 | 0 |
| Jun 2026 | 0 | 1 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 0 | 0 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| November 01, 2017 Filed Nov 3, 2017 21:15 UTC |
RINGO WILLIAM RDirector
|
Exercise / conversionCommon Stock | 1,000 | $7.20 | $7,200.00 |
DisclosureSEC source: 0001144204-17-056293 · tv478456_4.xml · nonDerivative · entry 1 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,465 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · shares: The option exercise and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 16, 2017 Filed Oct 17, 2017 22:30 UTC |
RINGO WILLIAM RDirector
|
Exercise / conversionStock Option (right to buy) · Derivative | 1,000 | $0.00 Strike: $7.20 | $0.00 |
DisclosureSEC source: 0001144204-17-052886 · tv477078_4.xml · derivative · entry 4 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 58,000 Underlying: Common Stock · 1,000 shares Expires 2024-07-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: This option, initially representing a right to purchase 64,000 shares, became exercisable in three equal installments on July 11, 2014; July 11, 2015; and July 11, 2016. Read SEC document |
| October 16, 2017 Filed Oct 17, 2017 22:30 UTC |
RINGO WILLIAM RDirector
|
SaleCommon Stock | 1,000 | $33.70 | $33,700.00 |
DisclosureSEC source: 0001144204-17-052886 · tv477078_4.xml · nonDerivative · entry 3 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,465 F1 · shares: The option exercise and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 16, 2017 Filed Oct 17, 2017 22:30 UTC |
RINGO WILLIAM RDirector
|
Exercise / conversionCommon Stock | 1,000 | $7.20 | $7,200.00 |
DisclosureSEC source: 0001144204-17-052886 · tv477078_4.xml · nonDerivative · entry 2 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,465 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · shares: The option exercise and sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| June 23, 2017 Filed Oct 17, 2017 22:30 UTC |
RINGO WILLIAM RDirector
|
GiftCommon Stock | 1,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001144204-17-052886 · tv477078_4.xml · nonDerivative · entry 1 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,465 Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 16:32 UTC |
AUERBACH MARKDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031036 · v468321_4.xml · derivative · entry 1 AUERBACH MARK · CIK 0001018007 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (i) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 20:32 UTC |
ALTIG ANTHONY EDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031035 · v468320_4.xml · derivative · entry 1 ALTIG ANTHONY E · CIK 0001215907 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (i) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 20:32 UTC |
DiMarchi Richard DDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031033 · v468319_4.xml · derivative · entry 1 DiMarchi Richard D · CIK 0001311733 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (i) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 20:31 UTC |
HOLUBIAK MYRON ZDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031032 · v468318_4.xml · derivative · entry 1 HOLUBIAK MYRON Z · CIK 0001199080 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (i) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 20:31 UTC |
RINGO WILLIAM RDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031031 · v468317_4.xml · derivative · entry 1 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (1) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| June 01, 2017 Filed Jun 5, 2017 20:31 UTC |
LEWIS ALANDirector
|
GrantStock Option (Right to Buy) · Derivative | 7,500 | $0.00 Strike: $25.96 | $0.00 |
DisclosureSEC source: 0001144204-17-031030 · v468316_4.xml · derivative · entry 1 LEWIS ALAN · CIK 0001207604 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,500 Underlying: Common Stock · 7,500 shares Expires 2027-06-01 F1 · derivative.exercise_date: The shares of Common Stock underlying the option will vest upon the earlier of (i) June 1, 2018 and (ii) the date of the Issuer's 2018 annual meeting of stockholders. Read SEC document |
| May 12, 2017 Filed May 16, 2017 20:31 UTC |
RINGO WILLIAM RDirector
|
SaleCommon Stock | 3,461 | $22.00 | $76,142.00 |
DisclosureSEC source: 0001144204-17-027950 · v467144_4.xml · nonDerivative · entry 1 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust Disclosed balance after: 0 F1 · ownership.nature: The securities are held by the William R. Ringo Rev. Trust (the "Trust"), and the Reporting Person is the sole trustee of the Trust. Read SEC document |
| May 10, 2017 Filed May 12, 2017 20:30 UTC |
RINGO WILLIAM RDirector
|
Exercise / conversionStock Option (Right to Buy) · Derivative | 5,000 | $0.00 Strike: $7.20 | $0.00 |
DisclosureSEC source: 0001144204-17-026921 · v466891_4.xml · derivative · entry 5 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 59,000 Underlying: Common Stock · 5,000 shares Expires 2024-07-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: 1/3 of this option vested on 7/11/2014, and the remaining 2/3 vested in equal installments on 7/11/2015 and 7/11/2016. This option was fully vested as of 7/11/2016. Read SEC document |
| May 10, 2017 Filed May 12, 2017 20:30 UTC |
RINGO WILLIAM RDirector
|
GiftCommon Stock | 3,461 | $0.00 | $0.00 |
DisclosureSEC source: 0001144204-17-026921 · v466891_4.xml · nonDerivative · entry 4 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · By Trust Disclosed balance after: 3,461 F2 · ownership.nature: The securities are held by the Trust and the Reporting Person is the sole trustee of the Trust. Read SEC document |
| May 10, 2017 Filed May 12, 2017 20:30 UTC |
RINGO WILLIAM RDirector
|
GiftCommon Stock | 3,461 | $0.00 | $0.00 |
DisclosureSEC source: 0001144204-17-026921 · v466891_4.xml · nonDerivative · entry 3 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,465 F1 · shares: This transaction involved a gift of securities by the Reporting Person to the Reporting Person's revocable trust, the William R. Ringo Rev. Trust (the "Trust"). The reporting Person is the sole trustee of the Trust. Read SEC document |
| May 10, 2017 Filed May 12, 2017 20:30 UTC |
RINGO WILLIAM RDirector
|
Tax withholdingCommon Stock | 1,539 | $23.39 | $35,997.21 |
DisclosureSEC source: 0001144204-17-026921 · v466891_4.xml · nonDerivative · entry 2 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,926 Read SEC document |
| May 10, 2017 Filed May 12, 2017 20:30 UTC |
RINGO WILLIAM RDirector
|
Exercise / conversionCommon Stock | 5,000 | $7.20 | $36,000.00 |
DisclosureSEC source: 0001144204-17-026921 · v466891_4.xml · nonDerivative · entry 1 RINGO WILLIAM R · CIK 0001238325 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 25,465 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 29, 2017 Filed Mar 31, 2017 16:12 UTC |
Rollins Thomas ESee Remarks
|
GrantStock Option (Right to Buy) · Derivative | 10,000 | $0.00 Strike: $25.34 | $0.00 |
DisclosureSEC source: 0001144204-17-018193 · v463066_4.xml · derivative · entry 1 Rollins Thomas E · CIK 0001667428 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common Stock · 10,000 shares Expires 2027-03-29 F1 · derivative.exercise_date: The options vest over two years as follows: 50% shall vest on the first anniversary of the date of grant, March 29, 2018; and the remaining 50% shall vest in 12 equal monthly installments, with the options becoming fully vested on March 29, 2019. Read SEC document |
| March 29, 2017 Filed Mar 31, 2017 20:15 UTC |
Small Derek ADirector · CEO, President and Director
|
GrantStock Option (right to buy) · Derivative | 40,000 | $0.00 Strike: $25.34 | $0.00 |
DisclosureSEC source: 0001144204-17-018203 · v463068_4.xml · derivative · entry 1 Small Derek A · CIK 0001613260 · Director · CEO, President and Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,000 Underlying: Common Stock · 40,000 shares Expires 2027-03-29 F1 · derivative.exercise_date: The options vest over two years as follows: 50% shall vest on the first anniversary of the date of grant, March 29, 2018; and the remaining 50% shall vest in 12 equal monthly installments, with the options becoming fully vested on March 29, 2019. Read SEC document |
| March 29, 2017 Filed Mar 31, 2017 20:16 UTC |
BARRETT DAVID JONATHANSee Remarks
|
GrantStock Option (right to buy) · Derivative | 25,000 | $0.00 Strike: $25.34 | $0.00 |
DisclosureSEC source: 0001144204-17-018209 · v463069_4.xml · derivative · entry 1 BARRETT DAVID JONATHAN · CIK 0001359072 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 25,000 Underlying: Common Stock · 25,000 shares Expires 2027-03-29 F1 · derivative.exercise_date: The options vest over two years as follows: 50% shall vest on the first anniversary of the date of grant, March 29, 2018; and the remaining 50% shall vest in 12 equal monthly installments, with the options becoming fully vested on March 29, 2019. Read SEC document |
| March 29, 2017 Filed Mar 31, 2017 20:13 UTC |
Colonno Richard JamesChief Scientific Officer
|
GrantStock Option (right to buy) · Derivative | 30,000 | $0.00 Strike: $25.34 | $0.00 |
DisclosureSEC source: 0001144204-17-018198 · v463067_4.xml · derivative · entry 1 Colonno Richard James · CIK 0001663018 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 30,000 Underlying: Common Stock · 30,000 shares Expires 2027-03-29 F1 · derivative.exercise_date: The options vest over two years as follows: 50% shall vest on the first anniversary of the date of grant, March 29, 2018; and the remaining 50% shall vest in 12 equal monthly installments, with the options becoming fully vested on March 29, 2019. Read SEC document |
| March 29, 2017 Filed Mar 31, 2017 20:11 UTC |
Lopatin Uri AChief Med. Off., VP Res. Dev.
|
GrantStock Option (right to buy) · Derivative | 12,500 | $0.00 Strike: $25.34 | $0.00 |
DisclosureSEC source: 0001144204-17-018188 · v463063_4.xml · derivative · entry 1 Lopatin Uri A · CIK 0001613259 · Chief Med. Off., VP Res. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,500 Underlying: Common Stock · 12,500 shares Expires 2027-03-29 F1 · derivative.exercise_date: The options vest over two years as follows: 50% shall vest on the first anniversary of the date of grant, March 29, 2018; and the remaining 50% shall vest in 12 equal monthly installments, with the options becoming fully vested on March 29, 2019. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.