ALNY

SEC source: 0001735276-25-000087 · edgardoc.xml · nonDerivative · entry 1

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,054

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024.

SEC source: 0001735276-25-000092 · edgardoc.xml · nonDerivative · entry 1

Garg Pushkal · CIK 0001829252 · EVP Chief R&D

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,072

F1 · kind: On March 1, 2024, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of thirty (30) percent of the shares subject to the PSU based on the achievement of a clinical milestone, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on August 15, 2025.

SEC source: 0001735276-25-000090 · edgardoc.xml · nonDerivative · entry 1

Poulton Jeffrey V. · CIK 0001782962 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,395

F1 · kind: On March 1, 2024, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of thirty (30) percent of the shares subject to the PSU based on the achievement of a clinical milestone, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on August 15, 2025.

SEC source: 0001735276-25-000091 · edgardoc.xml · nonDerivative · entry 1

Tanguler Tolga · CIK 0001849458 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,862

F1 · kind: On March 1, 2024, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of thirty (30) percent of the shares subject to the PSU based on the achievement of a clinical milestone, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on August 15, 2025.

SEC source: 0001735276-25-000089 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,200

F1 · kind: On March 1, 2024, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of thirty (30) percent of the shares subject to the PSU based on the achievement of a clinical milestone, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on August 15, 2025.

SEC source: 0001735276-25-000088 · edgardoc.xml · nonDerivative · entry 1

Fitzgerald Kevin Joseph · CIK 0001886431 · CSO & EVP, Head of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,115

F1 · kind: On March 1, 2024, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of thirty (30) percent of the shares subject to the PSU based on the achievement of a clinical milestone, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on August 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 24

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,454 shares

Expires 2033-05-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F19 · derivative.exercise_date: The stock option was fully vested as of May 18, 2024.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 23

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,032 shares

Expires 2031-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F18 · derivative.exercise_date: The stock option was fully vested as of July 15, 2022.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 22

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F17 · derivative.exercise_date: The stock option was fully vested as of May 16, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 21

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,581 shares

Expires 2030-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F16 · derivative.exercise_date: The stock option was fully vested as of July 1, 2021.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 20

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,153 shares

Expires 2032-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F15 · derivative.exercise_date: The stock option was fully vested as of May 18, 2023.

SEC source: 0001735276-25-000079 · edgardoc.xml · derivative · entry 19

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 9,000 shares

Expires 2029-06-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F14 · derivative.exercise_date: The stock option was fully vested as of July 1, 2020.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 17

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 911

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F12 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $442.44 to $443.10 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 16

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,552

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F11 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $441.41 to $442.11 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 15

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,757

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F10 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $440.24 to $440.93 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 14

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,995

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F9 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $438.91 to $439.89 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 13

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,297

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F8 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $437.85 to $438.71 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 12

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,383

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F7 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $436.84 to $437.83 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 11

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,305

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F6 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $435.79 to $436.35 The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 10

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,663

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F5 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $434.69 to $435.66. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 9

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,338

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F4 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $433.59 to $434.56. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 8

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,436

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F3 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $432.10 to $433.06. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 7

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,374

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

F2 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $430.39 to $431.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 6

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,359

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 5

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,905

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 4

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 24,873

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 3

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,645

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 2

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,064

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000079 · edgardoc.xml · nonDerivative · entry 1

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,911

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on May 15, 2025.

SEC source: 0001735276-25-000077 · edgardoc.xml · nonDerivative · entry 1

Fitzgerald Kevin Joseph · CIK 0001886431 · CSO & EVP, Head of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,264

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

SEC source: 0001735276-25-000075 · edgardoc.xml · derivative · entry 12

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 839

Underlying: Common Stock · 12,080 shares

Expires 2028-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

F4 · derivative.exercise_date: This stock option was fully vested and exercisable as of December 1, 2021.

SEC source: 0001735276-25-000075 · edgardoc.xml · derivative · entry 10

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 847

Underlying: Common Stock · 7,217 shares

Expires 2030-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

F3 · derivative.exercise_date: This stock option was fully vested and exercisable as of February 26, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 7

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,948

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 6

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,245

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 5

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,028

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · derivative · entry 11

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,919

Underlying: Common Stock · 12,081 shares

Expires 2028-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

F4 · derivative.exercise_date: This stock option was fully vested and exercisable as of December 1, 2021.

SEC source: 0001735276-25-000075 · edgardoc.xml · derivative · entry 9

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,064

Underlying: Common Stock · 19,559 shares

Expires 2030-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

F3 · derivative.exercise_date: This stock option was fully vested and exercisable as of February 26, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 4

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,948

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 3

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,119

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 2

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,588

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000075 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,029

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on September 12, 2024.

SEC source: 0001735276-25-000071 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,948

F1 · kind: The reported transaction involves a transfer of securities by bona fide gift for estate planning purposes to the Yvonne Greenstreet 2024 Irrevocable Trust Dtd 10/29/2024, of which the reporting person is neither the trustee nor a beneficiary.

SEC source: 0001735276-25-000072 · edgardoc.xml · derivative · entry 17

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,250 shares

Expires 2025-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F17 · derivative.exercise_date: The stock option was fully vested as of June 1, 2016.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 15

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,804

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F15 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $283.54 to $284.22. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 14

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,421

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F14 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $282.40 to $283.37. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 13

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,149

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F13 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $281.39 to $282.26. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 12

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,951

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F12 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $280.38 to $281.37. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 11

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,323

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F11 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $279.26 to $280.17. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 10

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,755

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F10 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $277.77 to $278.43. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

SEC source: 0001735276-25-000072 · edgardoc.xml · nonDerivative · entry 9

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,994

F1 · kind: This transaction was made pursuant to a Rule 10b5-1(c) trading plan adopted by the Reporting Person on November 12, 2024. The 11,250 options exercised and sold by the reporting person were due to expire on June 1, 2025.

F9 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $276.55 to $277.45. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.