ALGS

SEC source: 0001610717-26-000304 · form4.xml · derivative · entry 1

Chavez Margarita · CIK 0002032496 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000300 · form4.xml · derivative · entry 1

Hirth Peter · CIK 0001813780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000305 · form4.xml · derivative · entry 1

Preston Heather · CIK 0001606826 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000303 · form4.xml · derivative · entry 1

Martell Bridget A · CIK 0001629627 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000302 · form4.xml · derivative · entry 1

Scopa James Paul · CIK 0001356950 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000301 · form4.xml · derivative · entry 1

Nuechterlein Carole · CIK 0001665133 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2036-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2027 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-26-000095 · form4.xml · derivative · entry 1

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,310

Underlying: Common Stock · 23,310 shares

Expires 2036-03-09

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 9, 2026 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-26-000094 · form4.xml · derivative · entry 1

Aneja Nikhil · CIK 0002112438 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,450

Underlying: Common Stock · 9,450 shares

Expires 2036-03-09

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 9, 2026 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-26-000093 · form4.xml · derivative · entry 1

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,485

Underlying: Common Stock · 37,485 shares

Expires 2036-03-09

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 9, 2026 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-26-000092 · form4.xml · derivative · entry 1

BLATT LAWRENCE · CIK 0001242110 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 105,840

Underlying: Common Stock · 105,840 shares

Expires 2036-03-09

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 9, 2026 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000290 · form4.xml · derivative · entry 1

BLATT LAWRENCE · CIK 0001242110 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 179,800

Underlying: Common Stock · 179,800 shares

Expires 2035-07-16

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from July 16, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000289 · form4.xml · derivative · entry 1

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2035-07-16

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from July 16, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000286 · form4.xml · derivative · entry 1

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,185

Underlying: Common Stock · 40,185 shares

Expires 2035-07-16

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from July 16, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000255 · form4.xml · derivative · entry 1

Chavez Margarita · CIK 0002032496 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000257 · form4.xml · derivative · entry 1

Hirth Peter · CIK 0001813780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000259 · form4.xml · derivative · entry 1

Nuechterlein Carole · CIK 0001665133 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000256 · form4.xml · derivative · entry 1

Preston Heather · CIK 0001606826 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000258 · form4.xml · derivative · entry 1

Scopa James Paul · CIK 0001356950 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000254 · form4.xml · derivative · entry 1

Martell Bridget A · CIK 0001629627 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,860

Underlying: Common Stock · 5,860 shares

Expires 2035-06-25

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2026 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-25-000046 · form4.xml · derivative · entry 1

BLATT LAWRENCE · CIK 0001242110 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 140,103

Underlying: Common Stock · 140,103 shares

Expires 2035-02-28

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from February 28, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000045 · form4.xml · derivative · entry 1

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,693

Underlying: Common Stock · 21,693 shares

Expires 2035-02-28

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from February 28, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-25-000044 · form4.xml · derivative · entry 1

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,271

Underlying: Common Stock · 47,271 shares

Expires 2035-02-28

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from February 28, 2025 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000503 · form4.xml · derivative · entry 1

Achneck Hardean · CIK 0002037976 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2034-10-08

F1 · derivative.exercise_date: Twenty Five Percent (25%) of the shares subject to the option will vest on September 23, 2025 and the remaining shares subject to the option vest in 36 successive, equal monthly installments thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date.

SEC source: 0001610717-24-000466 · form4.xml · derivative · entry 1

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,880

Underlying: Common Stock · 10,880 shares

Expires 2034-09-04

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from September 4, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000465 · form4.xml · derivative · entry 1

BLATT LAWRENCE · CIK 0001242110 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,920

Underlying: Common Stock · 33,920 shares

Expires 2034-09-04

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from September 4, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000464 · form4.xml · derivative · entry 1

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,880

Underlying: Common Stock · 10,880 shares

Expires 2034-09-04

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from September 4, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000423 · form4.xml · derivative · entry 1

Chavez Margarita · CIK 0002032496 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2034-08-07

F1 · derivative.exercise_date: 1/36th of the total number of shares vest in thirty-six (36) successive and equal monthly installments measured from August 7, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the third anniversary of the Vesting Commencement Date.

SEC source: 0001610717-24-000422 · form4.xml · derivative · entry 1

Preston Heather · CIK 0001606826 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2034-08-07

F1 · derivative.exercise_date: 1/36th of the total number of shares vest in thirty-six (36) successive and equal monthly installments measured from August 7, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the third anniversary of the Vesting Commencement Date.

SEC source: 0001610717-24-000372 · form4.xml · derivative · entry 1

Hirth Peter · CIK 0001813780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-06-27

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2025 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-24-000371 · form4.xml · derivative · entry 1

Nuechterlein Carole · CIK 0001665133 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-06-27

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2025 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-24-000370 · form4.xml · derivative · entry 1

Scopa James Paul · CIK 0001356950 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-06-27

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2025 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-24-000369 · form4.xml · derivative · entry 1

Martell Bridget A · CIK 0001629627 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-06-27

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or immediately prior to the annual meeting in 2025 of the Issuer's stockholders, subject to continuous service to the Issuer through such vesting date.

SEC source: 0001610717-24-000124 · form4.xml · derivative · entry 1

McClure Matthew W. · CIK 0001927121 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,000

Underlying: Common Stock · 72,000 shares

Expires 2034-03-01

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 1, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000123 · form4.xml · derivative · entry 1

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 308,940

Underlying: Common Stock · 308,940 shares

Expires 2034-03-01

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 1, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000122 · form4.xml · derivative · entry 1

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,000

Underlying: Common Stock · 72,000 shares

Expires 2034-03-01

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 1, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000121 · form4.xml · derivative · entry 1

BLATT LAWRENCE · CIK 0001242110 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 965,435

Underlying: Common Stock · 965,435 shares

Expires 2024-03-01

F1 · derivative.exercise_date: 1/48th of the total number of shares vest in forty-eight (48) successive and equal monthly installments measured from March 1, 2024 (the "Vesting Commencement Date"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001610717-24-000100 · form4.xml · derivative · entry 6

McClure Matthew W. · CIK 0001927121 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,428

Underlying: Common Stock · 16,428 shares

Expires 2032-02-04

F3 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 23,000 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 16,428 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000100 · form4.xml · derivative · entry 5

McClure Matthew W. · CIK 0001927121 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,713

Underlying: Common Stock · 65,713 shares

Expires 2032-02-04

F2 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 92,000 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 65,713 shares, having an exercise price of $0.96 per share.

F5 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 75% of the total number of shares subject to the option on the one year anniversary of the date of the grant and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued service with the issuer on each such vesting date.

SEC source: 0001610717-24-000100 · form4.xml · derivative · entry 4

McClure Matthew W. · CIK 0001927121 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,183

Underlying: Common Stock · 75,183 shares

Expires 2030-12-01

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 255,626 of the issuer's shares granted to the reporting person on December 1, 2020. In exchange, on February 28, 2024, the reporting person received a replacement option, for 75,183 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000102 · form4.xml · derivative · entry 2

Hirth Peter · CIK 0001813780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,411

Underlying: Common Stock · 4,411 shares

Expires 2031-06-17

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 15,000 of the issuer's shares granted to the reporting person on June 17, 2021. In exchange, on February 28, 2024, the reporting person received a replacement option, for 4,411 shares, having an exercise price of $0.96 per share.

F2 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000101 · form4.xml · derivative · entry 2

Scopa James Paul · CIK 0001356950 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,823

Underlying: Common Stock · 8,823 shares

Expires 2031-04-26

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 30,000 of the issuer's shares granted to the reporting person on April 26, 2021. In exchange, on February 28, 2024, the reporting person received a replacement option, for 8,823 shares, having an exercise price of $0.96 per share.

F2 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000099 · form4.xml · derivative · entry 6

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,750

Underlying: Common Stock · 18,750 shares

Expires 2032-02-04

F3 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 26,250 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 18,750 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000099 · form4.xml · derivative · entry 5

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,998

Underlying: Common Stock · 74,998 shares

Expires 2032-02-04

F2 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 105,000 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 74,998 shares, having an exercise price of $0.96 per share.

F5 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 75% of the total number of shares subject to the option on the one year anniversary of the date of the grant and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued service with the issuer on each such vesting date.

SEC source: 0001610717-24-000099 · form4.xml · derivative · entry 4

Calhoun Lesley Ann · CIK 0001730866 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 51,833

Underlying: Common Stock · 51,833 shares

Expires 2030-12-01

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 176,237 of the issuer's shares granted to the reporting person on December 1, 2020. In exchange, on February 28, 2024, the reporting person received a replacement option, for 51,833 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000098 · form4.xml · derivative · entry 6

BLATT LAWRENCE · CIK 0001242110 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,749

Underlying: Common Stock · 57,749 shares

Expires 2032-02-04

F3 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 80,850 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 57,749 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000098 · form4.xml · derivative · entry 5

BLATT LAWRENCE · CIK 0001242110 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 230,999

Underlying: Common Stock · 230,999 shares

Expires 2032-02-04

F2 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 323,400 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 230,999 shares, having an exercise price of $0.96 per share.

F5 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 75% of the total number of shares subject to the option on the one year anniversary of the date of the grant and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued service with the issuer on each such vesting date.

SEC source: 0001610717-24-000098 · form4.xml · derivative · entry 4

BLATT LAWRENCE · CIK 0001242110 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 132,352

Underlying: Common Stock · 132,352 shares

Expires 2030-12-01

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 450,000 of the issuer's shares granted to the reporting person on December 1, 2020. In exchange, on February 28, 2024, the reporting person received a replacement option, for 132,352 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000097 · form4.xml · derivative · entry 6

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,750

Underlying: Common Stock · 18,750 shares

Expires 2032-02-04

F3 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 26,250 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 18,750 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.

SEC source: 0001610717-24-000097 · form4.xml · derivative · entry 5

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,998

Underlying: Common Stock · 74,998 shares

Expires 2032-02-04

F2 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 105,000 of the issuer's shares granted to the reporting person on February 4, 2022. In exchange, on February 28, 2024, the reporting person received a replacement option, for 74,998 shares, having an exercise price of $0.96 per share.

F5 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 75% of the total number of shares subject to the option on the one year anniversary of the date of the grant and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued service with the issuer on each such vesting date.

SEC source: 0001610717-24-000097 · form4.xml · derivative · entry 4

Symons Julian A. · CIK 0001824727 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,822

Underlying: Common Stock · 58,822 shares

Expires 2030-12-01

F1 · price: On February 27, 2024, the issuer canceled, pursuant to the issuer's option exchange program, an option for 200,000 of the issuer's shares granted to the reporting person on December 1, 2020. In exchange, on February 28, 2024, the reporting person received a replacement option, for 58,822 shares, having an exercise price of $0.96 per share.

F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary.