AKTX

SEC source: 0000950170-25-004577 · ownership.xml · nonDerivative · entry 1

Hombeck Torsten · CIK 0001983682 · CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200

F1 · security: Each American Depository Share ("ADS") represents 2,000 Ordinary Shares with a par value of $0.0001 per Ordinary Share of the Issuer.

F2 · kind: On January 10, 2025, the Reporting Person acquired 200 ADS at purchase price of $1.22 per ADS.

F2 · price: On January 10, 2025, the Reporting Person acquired 200 ADS at purchase price of $1.22 per ADS.

SEC source: 0000950170-25-016334 · ownership.xml · nonDerivative · entry 1

Gaslightwala Abizer · CIK 0002049375 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,500

F1 · security: Each American Depository Share ("ADS") represents 2,000 Ordinary Shares with a par value of $0.0001 per Ordinary Share of the Issuer.

F2 · kind: On January 13, 2025, the Reporting Person previously reported the purchase of 11,439 ADS at purchase price of $1.22 per ADS. The Reporting Person actually acquired 11,640 ADS at a price raning from $1.22 per ADS to $1.28 per ADS. The Reporting Person also previously reported the total amount of securities beneficially owned following transaction as 35,860 and omitted the ADS acquired on January 10, 2025. The revised amount of securities beneficially owned following the transaction is 47,500 ADS.

F2 · price: On January 13, 2025, the Reporting Person previously reported the purchase of 11,439 ADS at purchase price of $1.22 per ADS. The Reporting Person actually acquired 11,640 ADS at a price raning from $1.22 per ADS to $1.28 per ADS. The Reporting Person also previously reported the total amount of securities beneficially owned following transaction as 35,860 and omitted the ADS acquired on January 10, 2025. The revised amount of securities beneficially owned following the transaction is 47,500 ADS.

SEC source: 0000950170-25-004300 · ownership.xml · nonDerivative · entry 1

Neal James R · CIK 0001600865 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,216,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On January 9, 2025, the Reporting Person acquired 8,000,000 Ordinary Shares at a purchase price of $0.00065 per Ordinary Share.

F2 · price: On January 9, 2025, the Reporting Person acquired 8,000,000 Ordinary Shares at a purchase price of $0.00065 per Ordinary Share.

SEC source: 0000950170-25-002865 · ownership.xml · nonDerivative · entry 1

Gaslightwala Abizer · CIK 0002049375 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,720,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On January 3, 2025, the Reporting Person acquired 1,720,000 Ordinary Shares at purchase prices ranging from of $0.00064 to $0.000625 per Ordinary Share.

F2 · price: On January 3, 2025, the Reporting Person acquired 1,720,000 Ordinary Shares at purchase prices ranging from of $0.00064 to $0.000625 per Ordinary Share.

SEC source: 0000950170-25-002864 · ownership.xml · derivative · entry 3

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 152,672,000

Underlying: Ordinary Shares, par value $0.0001 per share · 152,672,000 shares

Expires 2035-01-03

F3 · derivative.exercise_price: The stock options have an exercise price of $0.000655 per Ordinary Share.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-25-002864 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,249,511,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On January 3, 2025, the Reporting Person acquired 208,000 Ordinary Shares at a purchase price of $0.0006 per Ordinary Share.

F2 · price: On January 3, 2025, the Reporting Person acquired 208,000 Ordinary Shares at a purchase price of $0.0006 per Ordinary Share.

SEC source: 0000950170-24-141158 · ownership.xml · nonDerivative · entry 1

Gaslightwala Abizer · CIK 0002049375 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 27, 2024, the Reporting Person acquired 40,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 27, 2024, the Reporting Person acquired 40,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-141162 · ownership.xml · nonDerivative · entry 2

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,249,303,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F3 · kind: On December 27, 2024 the Reporting Person acquired 400,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 26, 2024, the Reporting Person acquired 3,200,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-140808 · ownership.xml · nonDerivative · entry 1

Gaslightwala Abizer · CIK 0002049375 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 26, 2024, the Reporting Person acquired 30,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 26, 2024, the Reporting Person acquired 30,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-141162 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,248,903,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 26, 2024, the Reporting Person acquired 3,200,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 26, 2024, the Reporting Person acquired 3,200,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-140807 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,245,703,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 24, 2024, the Reporting Person acquired 7,500,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 24, 2024, the Reporting Person acquired 7,500,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-140430 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,238,203,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 23, 2024, the Reporting Person acquired 1,400,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 23, 2024, the Reporting Person acquired 1,400,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-140431 · ownership.xml · nonDerivative · entry 1

Neal James R · CIK 0001600865 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,216,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 23, 2024, the Reporting Person acquired 2,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 23, 2024, the Reporting Person acquired 2,000,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-140427 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,236,803,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 20, 2024, the Reporting Person acquired 1,400,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

F2 · price: On December 20, 2024, the Reporting Person acquired 1,400,000 Ordinary Shares at a purchase price of $0.0005 per Ordinary Share.

SEC source: 0000950170-24-132936 · ownership.xml · derivative · entry 4

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 419,286,000

Underlying: Ordinary Shares, par value $0.0001 per share · 419,286,000 shares

Expires 2027-12-02

F4 · derivative.exercise_price: The warrants have an exercise price of $0.001130 per Ordinary Share.

F2 · kind: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F2 · price: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-132936 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 5,235,403,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F2 · price: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

SEC source: 0000950170-24-132929 · ownership.xml · derivative · entry 4

Prudo-Chlebosz Raymond · CIK 0001653262 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 419,286,000

Underlying: Ordinary Shares, par value $0.0001 per share · 419,286,000 shares

Expires 2027-12-02

F3 · derivative.exercise_price: The warrants have an exercise price of $0.001130 per Ordinary Share.

F2 · kind: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F2 · price: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-132929 · ownership.xml · nonDerivative · entry 1

Prudo-Chlebosz Raymond · CIK 0001653262 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,077,124,600

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

F2 · price: On December 2, 2024, the Reporting Person acquired 419,286,000 Ordinary Shares and accompanying warrants to purchase up to 419,286,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of November 13, 2024. The combined purchase price was $0.001193 per Ordinary Share and accompanying warrant.

SEC source: 0000950170-24-132936 · ownership.xml · derivative · entry 3

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 162,604,000

Underlying: Ordinary Shares, par value $0.0001 per share · 162,604,000 shares

Expires 2034-11-30

F3 · derivative.exercise_price: The stock options have an exercise price of $0.000615 per Ordinary Share.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-128190 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 4,816,117,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares ("ADSs"), each of which currently represents 2,000 Ordinary Shares.

F2 · kind: This Form 4 reports securities transacted pursuant to the terms of the Agreement and Plan of Merger, dated as of March 4, 2024, as amended, by and among the Issuer, Peak Bio Inc. ("Peak Bio"), and Pegasus Merger Sub, Inc., a wholly-owned subsidiary of Issuer ("Merger Sub"), pursuant to which Merger Sub merged with and into Peak Bio effective as of November 14, 2024, with Peak Bio surviving as a wholly owned subsidiary of the Issuer (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding share of common stock of Peak Bio (each, a "Peak Share") was cancelled and converted into the right to receive 0.2935 (the "Exchange Ratio") ADSs.

F2 · shares: This Form 4 reports securities transacted pursuant to the terms of the Agreement and Plan of Merger, dated as of March 4, 2024, as amended, by and among the Issuer, Peak Bio Inc. ("Peak Bio"), and Pegasus Merger Sub, Inc., a wholly-owned subsidiary of Issuer ("Merger Sub"), pursuant to which Merger Sub merged with and into Peak Bio effective as of November 14, 2024, with Peak Bio surviving as a wholly owned subsidiary of the Issuer (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding share of common stock of Peak Bio (each, a "Peak Share") was cancelled and converted into the right to receive 0.2935 (the "Exchange Ratio") ADSs.

F3 · shares: Represents the number of Ordinary Shares acquired by the Reporting Person from the exchange of Peak Shares held by the Reporting Person at the Effective Time in accordance with the Exchange Ratio.

F2 · price: This Form 4 reports securities transacted pursuant to the terms of the Agreement and Plan of Merger, dated as of March 4, 2024, as amended, by and among the Issuer, Peak Bio Inc. ("Peak Bio"), and Pegasus Merger Sub, Inc., a wholly-owned subsidiary of Issuer ("Merger Sub"), pursuant to which Merger Sub merged with and into Peak Bio effective as of November 14, 2024, with Peak Bio surviving as a wholly owned subsidiary of the Issuer (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding share of common stock of Peak Bio (each, a "Peak Share") was cancelled and converted into the right to receive 0.2935 (the "Exchange Ratio") ADSs.

SEC source: 0000950170-24-120185 · ownership.xml · derivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,684,000

Underlying: Ordinary Shares, par value $0.0001 per share · 79,684,000 shares

Expires 2034-10-31

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001255 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-111796 · ownership.xml · derivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 175,080,000

Underlying: Ordinary Shares, par value $0.0001 per share · 175,080,000 shares

Expires 2034-09-30

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001490 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-107828 · ownership.xml · derivative · entry 1

Bazemore Robert B · CIK 0001620152 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000,000

Underlying: Ordinary Shares, par value $0.0001 per share · 5,000,000 shares

Expires 2034-09-17

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001655 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.exercise_date: Non-qualified stock option granted under the Issuer's 2023 Equity Incentive Plan. The stock option vests and becomes exercisable ratably in three equal installments with the first installment vesting on the date of the first Annual General Meeting ("AGM") following the date of the grant, and with the second and third installments vesting, respectively, on the dates of the second and third AGM's following the date of the grant, subject to the non-employee director's continued service with the Issuer.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-080542 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,396,000

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · shares: These shares represent restricted stock units ("RSUs") granted under the Issuer's 2023 Equity Incentive Plan, with each such RSU representing the right to receive one ordinary share, par value $0.0001. One-hundered percent (100%) of the RSUs vested on the date of grant, or June 30, 2024.

SEC source: 0000950170-24-080538 · ownership.xml · derivative · entry 1

Grissinger Michael · CIK 0001757601 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000,000

Underlying: Ordinary Shares, par value $0.0001 per share · 5,000,000 shares

Expires 2034-06-28

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001395 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.exercise_date: Non-qualified stock option granted under the Issuer's 2023 Equity Incentive Plan. One-hundred percent (100%) of the stock option vests and becomes exercisable on the date of the Issuer's 2025 Annual General Meeting of Shareholders, subject to continued service with the Issuer.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-080541 · ownership.xml · derivative · entry 1

WILLIAMS DONALD A · CIK 0001241435 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000,000

Underlying: Ordinary Shares, par value $0.0001 per share · 5,000,000 shares

Expires 2034-06-28

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001395 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.exercise_date: Non-qualified stock option granted under the Issuer's 2023 Equity Incentive Plan. One-hundred percent (100%) of the stock option vests and becomes exercisable on the date of the Issuer's 2025 Annual General Meeting of Shareholders, subject to continued service with the Issuer.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-080540 · ownership.xml · derivative · entry 1

Hashad Mohamed Wa'el Ahmed · CIK 0001966752 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000,000

Underlying: Ordinary Shares, par value $0.0001 per share · 5,000,000 shares

Expires 2034-06-28

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001395 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.exercise_date: Non-qualified stock option granted under the Issuer's 2023 Equity Incentive Plan. One-hundred percent (100%) of the stock option vests and becomes exercisable on the date of the Issuer's 2025 Annual General Meeting of Shareholders, subject to continued service with the Issuer.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-080539 · ownership.xml · derivative · entry 1

Prudo-Chlebosz Raymond · CIK 0001653262 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000,000

Underlying: Ordinary Shares, par value $0.0001 per share · 10,000,000 shares

Expires 2034-06-28

F1 · derivative.exercise_price: The stock options have an exercise price of $0.001395 per ordinary share, par value $0.0001 per share ("Ordinary Share").

F2 · derivative.exercise_date: Non-qualified stock option granted under the Issuer's 2023 Equity Incentive Plan. One-hundred percent (100%) of the stock option vests and becomes exercisable on the date of the Issuer's 2025 Annual General Meeting of Shareholders, subject to continued service with the Issuer.

F3 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-068771 · ownership.xml · derivative · entry 2

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 1,326,258,000

Underlying: Ordinary Shares, par value $0.0001 per share · 1,326,258,000 shares

Expires 2027-05-31

F3 · derivative.exercise_price: The warrants have an exercise price of $0.000895 per Ordinary Share.

F2 · kind: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F2 · price: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-068771 · ownership.xml · nonDerivative · entry 1

Patel Samir Rashmikant · CIK 0001702447 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · PranaBio Investments LLC

Disclosed balance after: 3,411,495,500

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F2 · price: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

SEC source: 0000950170-24-068770 · ownership.xml · derivative · entry 4

Prudo-Chlebosz Raymond · CIK 0001653262 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,326,258,000

Underlying: Ordinary Shares, par value $0.0001 per share · 1,326,258,000 shares

Expires 2027-05-31

F3 · derivative.exercise_price: The warrants have an exercise price of $0.000895 per Ordinary Share.

F2 · kind: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F2 · price: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F1 · derivative.underlying: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

SEC source: 0000950170-24-068770 · ownership.xml · nonDerivative · entry 1

Prudo-Chlebosz Raymond · CIK 0001653262 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,657,838,600

F1 · security: The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents 2,000 Ordinary Shares.

F2 · kind: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

F2 · price: On May 31, 2024, the Reporting Person acquired 1,326,258,000 Ordinary Shares and accompanying warrants to purchase up to 1,326,258,000 Ordinary Shares in a private placement by the Issuer pursuant to the terms of a Securities Purchase Agreement dated as of May 29, 2024. The combined purchase price was $0.0009425 per Ordinary Share and accompanying warrant.

SEC source: 0000950170-24-053000 · ownership.xml · nonDerivative · entry 1

DICICCO WENDY F · CIK 0001225165 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,473,915

F1 · shares: These shares represent restricted stock units ("RSUs") granted under the Issuer's 2023 Equity Incentive Plan, with each such RSU representing the right to receive one ordinary share, par value $0.0001. One-hundered percent (100%) of the RSUs shall vest on May 1, 2025 (first anniversary of the date of grant), subject to the Reporting Person's continued service with the Issuer on the vesting date. Notwithstanding the foregoing, should the Issuer terminate the Reporting Person for any reason other than for cause prior to the vesting date, the RSUs will continue to vest through the first anniversary of the date of grant or be accelerated, at the Issuer's option.

SEC source: 0000950170-24-050854 · ownership.xml · nonDerivative · entry 1

Jacques Rachelle Suzanne · CIK 0001772610 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,018,027,792

F1 · shares: These shares represent restricted stock units ("RSUs"), with each such RSU representing the right to receive one ordinary share, par value $0.0001. 50% of the RSUs shall vest on March 28, 2025, with the remainder vesting in 12 equal monthly installments thereafter, subject to the Reporting Person's continued service with the Issuer on each such vesting date.