Last 12 months
Inside the activity.
0 purchase rows · 39 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 2 |
| Dec 2025 | 0 | 6 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 21 |
| Apr 2026 | 0 | 7 |
| May 2026 | 0 | 0 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 1 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| November 01, 2017 Filed Nov 3, 2017 20:01 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 2,146 | $31.64 | $67,899.44 |
DisclosureSEC source: 0001209191-17-059138 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,410 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 17, 2017 Filed Oct 18, 2017 21:34 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $71.10 | $71,100.00 |
DisclosureSEC source: 0001209191-17-057318 · doc4.xml · nonDerivative · entry 4 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 83,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $70.71 to $71.51. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| October 17, 2017 Filed Oct 18, 2017 21:34 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $71.10 | $71,100.00 |
DisclosureSEC source: 0001209191-17-057318 · doc4.xml · nonDerivative · entry 3 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 83,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $70.71 to $71.51. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 16, 2017 Filed Oct 18, 2017 21:34 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $71.09 | $71,090.00 |
DisclosureSEC source: 0001209191-17-057318 · doc4.xml · nonDerivative · entry 2 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 84,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $70.58 to $71.83. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| October 16, 2017 Filed Oct 18, 2017 21:34 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $71.09 | $71,090.00 |
DisclosureSEC source: 0001209191-17-057318 · doc4.xml · nonDerivative · entry 1 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 84,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $70.58 to $71.83. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 04, 2017 Filed Oct 5, 2017 22:35 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 10,470 | $70.00 | $732,900.00 |
DisclosureSEC source: 0001209191-17-056193 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 0 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · ownership.nature: Shares held by a spousal lifetime access trust, of which the reporting person's wife is trustee. Read SEC document |
| October 04, 2017 Filed Oct 5, 2017 22:33 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 80,000 | $0.00 Strike: $0.30 | $0.00 |
DisclosureSEC source: 0001209191-17-056191 · doc4.xml · derivative · entry 5 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 32,656 Underlying: Common stock · 80,000 shares Expires 2019-08-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| October 04, 2017 Filed Oct 5, 2017 22:33 UTC |
Schenkein David PDirector · Chief Executive Officer
|
SaleCommon stock | 80,000 | $70.14 | $5,611,200.00 |
DisclosureSEC source: 0001209191-17-056191 · doc4.xml · nonDerivative · entry 2 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $70.00 to $70.68. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 04, 2017 Filed Oct 5, 2017 22:33 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 80,000 | $0.30 | $24,200.00 |
DisclosureSEC source: 0001209191-17-056191 · doc4.xml · nonDerivative · entry 1 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 80,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 955 | $0.00 Strike: $31.64 | $0.00 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · derivative · entry 7 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 34,331 Underlying: Common stock · 955 shares Expires 2024-03-04 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · derivative.exercise_date: This option was granted on March 5, 2014. The shares underlying this option vest as to 25% of the shares on March 5, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 1,191 | $0.00 Strike: $9.05 | $0.00 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · derivative · entry 6 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 34,090 Underlying: Common stock · 1,191 shares Expires 2023-04-30 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F5 · derivative.exercise_date: This option was originally granted on April 30, 2013 for the purchase of 68,181 shares of common stock. The option vests as to 50% of the underlying shares upon the achievement of a performance milestone, and as to the remaining 50% of upon the achievement of a second performance milestone. The Company's board of directors determined that the first performance milestone was achieved on December 3, 2015, resulting in the vesting of this option as to 34,091 shares. On January 26, 2017, the Company's board of directors determined that the second performance milestone was achieved, resulting in the vesting of this option as to the remaining 34,090 shares. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 955 | $67.23 | $64,204.65 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · nonDerivative · entry 4 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,264 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $66.43 to $67.68. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 955 | $31.64 | $30,216.20 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · nonDerivative · entry 3 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,219 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 1,191 | $67.23 | $80,070.93 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · nonDerivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,264 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $66.43 to $67.68. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:32 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 1,191 | $9.05 | $10,778.55 |
DisclosureSEC source: 0001209191-17-055856 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,455 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:29 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 6,000 | $0.00 Strike: $0.30 | $0.00 |
DisclosureSEC source: 0001209191-17-055844 · doc4.xml · derivative · entry 5 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 112,656 Underlying: Common stock · 6,000 shares Expires 2019-08-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:29 UTC |
Schenkein David PDirector · Chief Executive Officer
|
SaleCommon stock | 6,000 | $66.76 | $400,560.00 |
DisclosureSEC source: 0001209191-17-055844 · doc4.xml · nonDerivative · entry 2 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $66.21 to $67.18. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| October 02, 2017 Filed Oct 4, 2017 20:29 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 6,000 | $0.30 | $1,815.00 |
DisclosureSEC source: 0001209191-17-055844 · doc4.xml · nonDerivative · entry 1 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| September 18, 2017 Filed Sep 20, 2017 20:11 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 35,000 | $0.00 Strike: $0.30 | $0.00 |
DisclosureSEC source: 0001209191-17-053461 · doc4.xml · derivative · entry 5 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 118,656 Underlying: Common stock · 35,000 shares Expires 2019-08-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F7 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| September 18, 2017 Filed Sep 20, 2017 20:11 UTC |
Schenkein David PDirector · Chief Executive Officer
|
SaleCommon stock | 35,000 | $67.12 | $2,349,200.00 |
DisclosureSEC source: 0001209191-17-053461 · doc4.xml · nonDerivative · entry 3 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F4 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $66.77 to $67.38. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| September 18, 2017 Filed Sep 20, 2017 20:11 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 35,000 | $0.30 | $10,587.50 |
DisclosureSEC source: 0001209191-17-053461 · doc4.xml · nonDerivative · entry 2 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 35,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| September 14, 2017 Filed Sep 15, 2017 20:54 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $65.71 | $65,710.00 |
DisclosureSEC source: 0001209191-17-053010 · doc4.xml · nonDerivative · entry 4 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 85,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $65.45 to $66.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| September 14, 2017 Filed Sep 15, 2017 20:54 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $65.71 | $65,710.00 |
DisclosureSEC source: 0001209191-17-053010 · doc4.xml · nonDerivative · entry 3 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 85,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $65.45 to $66.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| September 13, 2017 Filed Sep 15, 2017 20:54 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $65.47 | $65,470.00 |
DisclosureSEC source: 0001209191-17-053010 · doc4.xml · nonDerivative · entry 2 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 86,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $65.15 to $65.92. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| September 13, 2017 Filed Sep 15, 2017 20:54 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 1,000 | $65.47 | $65,470.00 |
DisclosureSEC source: 0001209191-17-053010 · doc4.xml · nonDerivative · entry 1 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 86,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $65.15 to $65.92. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| September 11, 2017 Filed Sep 13, 2017 20:37 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 15,000 | $65.00 | $975,000.00 |
DisclosureSEC source: 0001209191-17-052622 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 10,470 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · ownership.nature: Shares held by a spousal lifetime access trust, of which the reporting person's wife is trustee. Read SEC document |
| September 11, 2017 Filed Sep 13, 2017 20:38 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 6,000 | $0.00 Strike: $35.16 | $0.00 |
DisclosureSEC source: 0001209191-17-052627 · doc4.xml · derivative · entry 3 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 109,000 Underlying: Common stock · 6,000 shares Expires 2024-05-30 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · derivative.exercise_date: This option was granted on May 31, 2014. The shares underlying this option vest as to 25% of the underlying shares on May 13, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| September 11, 2017 Filed Sep 13, 2017 20:38 UTC |
Bowden ChristopherChief Medical Officer
|
SaleCommon stock | 6,000 | $65.00 | $390,000.00 |
DisclosureSEC source: 0001209191-17-052627 · doc4.xml · nonDerivative · entry 2 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 881 F3 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| September 11, 2017 Filed Sep 13, 2017 20:38 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionCommon stock | 6,000 | $35.16 | $210,960.00 |
DisclosureSEC source: 0001209191-17-052627 · doc4.xml · nonDerivative · entry 1 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,881 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · balance_after: Includes 881 shares purchased through the Company's employee stock purchase plan. Read SEC document |
| September 07, 2017 Filed Sep 20, 2017 20:11 UTC |
Schenkein David PDirector · Chief Executive Officer
|
GiftCommon stock | 500 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-17-053461 · doc4.xml · nonDerivative · entry 1 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 271,772 F1 · kind: This disposition reflects a gift of 500 shares to a charitable trust. F2 · ownership.nature: Shares held by David P. Schenkein 2004 Revocable Trust, of which the reporting person is trustee and beneficiary. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:25 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 2,146 | $0.00 Strike: $9.05 | $0.00 |
DisclosureSEC source: 0001209191-17-051435 · doc4.xml · derivative · entry 4 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 35,281 Underlying: Common stock · 2,146 shares Expires 2023-04-30 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F5 · derivative.exercise_date: This option was originally granted on April 30, 2013 for the purchase of 68,181 shares of common stock. The option vests as to 50% of the underlying shares upon the achievement of a performance milestone, and as to the remaining 50% of upon the achievement of a second performance milestone. The Company's board of directors determined that the first performance milestone was achieved on December 3, 2015, resulting in the vesting of this option as to 34,091 shares. On January 26, 2017, the Company's board of directors determined that the second performance milestone was achieved, resulting in the vesting of this option as to the remaining 34,090 shares. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:25 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 2,146 | $61.99 | $133,030.54 |
DisclosureSEC source: 0001209191-17-051435 · doc4.xml · nonDerivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,264 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.31 to $62.51. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:25 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 2,146 | $9.05 | $19,421.30 |
DisclosureSEC source: 0001209191-17-051435 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,410 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:22 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 6,000 | $0.00 Strike: $0.30 | $0.00 |
DisclosureSEC source: 0001209191-17-051430 · doc4.xml · derivative · entry 5 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 153,656 Underlying: Common stock · 6,000 shares Expires 2019-08-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:22 UTC |
Schenkein David PDirector · Chief Executive Officer
|
SaleCommon stock | 6,000 | $62.20 | $373,200.00 |
DisclosureSEC source: 0001209191-17-051430 · doc4.xml · nonDerivative · entry 2 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.30 to $63.35. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| September 01, 2017 Filed Sep 5, 2017 21:22 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 6,000 | $0.30 | $1,815.00 |
DisclosureSEC source: 0001209191-17-051430 · doc4.xml · nonDerivative · entry 1 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| August 23, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $57.07 | $28,535.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 8 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 87,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F8 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.33. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F5 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| August 23, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $57.07 | $28,535.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 7 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 87,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F8 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.33. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| August 23, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $57.09 | $28,545.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 6 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 87,934 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F7 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F5 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| August 23, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $57.09 | $28,545.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 5 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 87,894 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F7 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| August 22, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $56.61 | $28,305.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 4 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 88,434 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.33 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F5 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| August 22, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $56.61 | $28,305.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 3 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 88,394 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.33 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| August 22, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $56.63 | $28,315.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 2 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 88,934 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.31 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F4 · balance_after: This amount reflects 4,197 shares transferred from a grantor retained annuity trust distribution on July 28, 2017. F5 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse. Read SEC document |
| August 22, 2017 Filed Aug 24, 2017 20:13 UTC |
Cantley Lewis Clayton Jr.Director
|
SaleCommon stock | 500 | $56.63 | $28,315.00 |
DisclosureSEC source: 0001209191-17-050096 · doc4.xml · nonDerivative · entry 1 Cantley Lewis Clayton Jr. · CIK 0001581950 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 88,894 F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.31 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. F3 · balance_after: This amount reflects 4,197 shares transferred from indirect to direct ownership from a grantor retained annuity trust distribution on July 28, 2017. Read SEC document |
| August 02, 2017 Filed Aug 3, 2017 21:29 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 21,000 | $60.06 | $1,261,260.00 |
DisclosureSEC source: 0001209191-17-047459 · doc4.xml · nonDerivative · entry 3 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 25,470 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · ownership.nature: Shares held by a spousal lifetime access trust, of which the reporting person's wife is trustee. Read SEC document |
| August 02, 2017 Filed Aug 3, 2017 21:26 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 24,000 | $0.00 Strike: $0.30 | $0.00 |
DisclosureSEC source: 0001209191-17-047452 · doc4.xml · derivative · entry 8 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 159,656 Underlying: Common stock · 24,000 shares Expires 2019-08-12 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F7 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| August 02, 2017 Filed Aug 3, 2017 21:26 UTC |
Schenkein David PDirector · Chief Executive Officer
|
SaleCommon stock | 24,000 | $60.55 | $1,453,200.00 |
DisclosureSEC source: 0001209191-17-047452 · doc4.xml · nonDerivative · entry 4 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.00 to $61.71. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
| August 02, 2017 Filed Aug 3, 2017 21:26 UTC |
Schenkein David PDirector · Chief Executive Officer
|
Exercise / conversionCommon stock | 24,000 | $0.30 | $7,260.00 |
DisclosureSEC source: 0001209191-17-047452 · doc4.xml · nonDerivative · entry 3 Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 24,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| August 01, 2017 Filed Aug 3, 2017 21:29 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 2,146 | $0.00 Strike: $9.05 | $0.00 |
DisclosureSEC source: 0001209191-17-047459 · doc4.xml · derivative · entry 4 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 37,427 Underlying: Common stock · 2,146 shares Expires 2023-04-30 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F5 · derivative.exercise_date: This option was originally granted on April 30, 2013 for the purchase of 68,181 shares of common stock. The option vests as to 50% of the underlying shares upon the achievement of a performance milestone, and as to the remaining 50% of upon the achievement of a second performance milestone. The Company's board of directors determined that the first performance milestone was achieved on December 3, 2015, resulting in the vesting of this option as to 34,091 shares. On January 26, 2017, the Company's board of directors determined that the second performance milestone was achieved, resulting in the vesting of this option as to the remaining 34,090 shares. Read SEC document |
| August 01, 2017 Filed Aug 3, 2017 21:29 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 2,146 | $55.05 | $118,137.30 |
DisclosureSEC source: 0001209191-17-047459 · doc4.xml · nonDerivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,264 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.00 to $55.58. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.