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Nasdaq · USD

AGIO

AGIOS PHARMACEUTICALS, INC.

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Tapewire entity
4499
SEC CIK
0001439222
Parsed reports
520

Last 12 months

Inside the activity.

0 purchase rows · 39 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202506
Jan 202601
Feb 202600
Mar 2026021
Apr 202607
May 202600
Jun 202600
Jul 202601
Aug 202601
Sep 202600
Oct 202600

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 12, 2018 Filed Jan 26, 2018 16:23 UTC
Alenson CarmanPrincipal Accounting Officer
Exercise / conversionStock option (right to buy) · Derivative 2,150 $0.00 Strike: $52.29 $0.00
Disclosure

SEC source: 0001209191-18-005587 · doc4.xml · derivative · entry 3

Alenson Carman · CIK 0001688865 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,850

Underlying: Common stock · 2,150 shares

Expires 2026-11-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · derivative.exercise_date: This option was granted on November 7, 2016. The shares underlying this option vest as to 25% of the underlying shares on November 7, 2017, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 12, 2018 Filed Jan 26, 2018 16:23 UTC
Alenson CarmanPrincipal Accounting Officer
SaleCommon stock 2,150 $75.00 $161,250.00
Disclosure

SEC source: 0001209191-18-005587 · doc4.xml · nonDerivative · entry 2

Alenson Carman · CIK 0001688865 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 12, 2018 Filed Jan 26, 2018 16:23 UTC
Alenson CarmanPrincipal Accounting Officer
Exercise / conversionCommon stock 2,150 $52.29 $112,423.50
Disclosure

SEC source: 0001209191-18-005587 · doc4.xml · nonDerivative · entry 1

Alenson Carman · CIK 0001688865 · Principal Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,150

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 10, 2018 Filed Jan 12, 2018 21:34 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock options (right to buy) · Derivative 3,000 $0.00 Strike: $0.47 $0.00
Disclosure

SEC source: 0001209191-18-003434 · doc4.xml · derivative · entry 3

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,867

Underlying: Common stock · 3,000 shares

Expires 2020-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · derivative.exercise_date: This option was granted on December 7, 2010. The shares underlying this option vested as to 25% of the shares upon the achievement of a performance milestone, and as to the remaining 75% in 36 equal monthly installments thereafter. The performance criteria was met on June 23, 2015.

Read SEC document
January 10, 2018 Filed Jan 12, 2018 21:34 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 3,000 $65.00 $195,000.00
Disclosure

SEC source: 0001209191-18-003434 · doc4.xml · nonDerivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,059

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 10, 2018 Filed Jan 12, 2018 21:34 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 3,000 $0.47 $1,402.50
Disclosure

SEC source: 0001209191-18-003434 · doc4.xml · nonDerivative · entry 1

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,059

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 631 $60.45 $38,143.95
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 10

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 79,515

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.00 to $60.79. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 631 $60.45 $38,143.95
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 9

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,475

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.00 to $60.79. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 288 $59.68 $17,187.84
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 8

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 80,146

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.99 to $59.95. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 288 $59.68 $17,187.84
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 7

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,106

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.99 to $59.95. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 204 $60.01 $12,242.04
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 6

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 80,434

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.62 to $60.55. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 204 $60.01 $12,242.04
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 5

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,394

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.62 to $60.55. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 254 $58.95 $14,973.30
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 4

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 80,638

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.58 to $59.21. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 253 $58.95 $14,914.35
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 3

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,598

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.58 to $59.21. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 542 $57.90 $31,381.80
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 2

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 80,892

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $57.48 to $58.30. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:23 UTC SaleCommon stock 543 $57.90 $31,439.70
Disclosure

SEC source: 0001209191-17-064704 · doc4.xml · nonDerivative · entry 1

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,851

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $57.48 to $58.30. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock option (right to buy) · Derivative 31,818 $0.00 Strike: $2.34 $0.00
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · derivative · entry 6

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,818

Underlying: Common stock · 31,818 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option was granted on April 6, 2012 for the purchase of 63,636 shares of common stock. The option vests as to 25% of the shares upon the achievement of a performance milestone, as to an additional 50% upon the achievement of a second performance milestone, and as to the remaining 25% on the first anniversary of the first date that both performance milestones were achieved. The performance criteria for the first performance milestone were met on March 18, 2013. The performance criteria for the second performance milestone were met on April 4, 2014, resulting in the vesting of the option as to 31,818 shares, and the remaining 15,909 shares vested on April 4, 2015.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock option (right to buy) · Derivative 102 $0.00 Strike: $0.47 $0.00
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · derivative · entry 5

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,867

Underlying: Common stock · 102 shares

Expires 2020-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option was granted on December 7, 2010. The shares underlying this option vested as to 25% of the shares upon the achievement of a performance milestone, and as to the remaining 75% in 36 equal monthly installments thereafter. The performance criteria was met on June 23, 2015.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock option (right to buy) · Derivative 14,875 $0.00 Strike: $0.47 $0.00
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · derivative · entry 4

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 14,875 shares

Expires 2020-12-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option was granted on December 7, 2010. The shares underlying this option vest as to 25% of the shares on September 20, 2011, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 31,818 $2.34 $74,374.58
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · nonDerivative · entry 3

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,059

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 102 $0.47 $47.69
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · nonDerivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,241

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 06, 2017 Filed Dec 8, 2017 21:22 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 14,875 $0.47 $6,954.06
Disclosure

SEC source: 0001209191-17-064701 · doc4.xml · nonDerivative · entry 1

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,139

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 03, 2017 Filed Dec 5, 2017 21:15 UTC GrantStock option (right to buy) · Derivative 16,000 $0.00 Strike: $61.17 $0.00
Disclosure

SEC source: 0001209191-17-063895 · doc4.xml · derivative · entry 1

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common stock · 16,000 shares

Expires 2027-12-02

F1 · derivative.exercise_date: This option was granted on December 3, 2017. The shares underlying this option vest as to 25% of the underlying shares on December 2, 2018, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:28 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 6,000 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-17-063927 · doc4.xml · derivative · entry 6

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,656

Underlying: Common stock · 6,000 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:28 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 400 $62.08 $24,832.00
Disclosure

SEC source: 0001209191-17-063927 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $62.04 to $62.10. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:28 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 5,600 $61.51 $344,456.00
Disclosure

SEC source: 0001209191-17-063927 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 400

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.03 to $61.91. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:28 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 6,000 $0.30 $1,815.00
Disclosure

SEC source: 0001209191-17-063927 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:09 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock options (right to buy) · Derivative 2,146 $0.00 Strike: $31.64 $0.00
Disclosure

SEC source: 0001209191-17-063884 · doc4.xml · derivative · entry 5

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,039

Underlying: Common stock · 2,146 shares

Expires 2024-03-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · derivative.exercise_date: This option was granted on March 5, 2014. The shares underlying this option vest as to 25% of the shares on March 5, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:09 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 700 $61.76 $43,232.00
Disclosure

SEC source: 0001209191-17-063884 · doc4.xml · nonDerivative · entry 4

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,264

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.45 to $62.24. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:09 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 846 $60.63 $51,292.98
Disclosure

SEC source: 0001209191-17-063884 · doc4.xml · nonDerivative · entry 3

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,964

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.35 to $61.06. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:09 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 600 $59.89 $35,934.00
Disclosure

SEC source: 0001209191-17-063884 · doc4.xml · nonDerivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,810

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.29 to $60.26. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
December 01, 2017 Filed Dec 5, 2017 21:09 UTC
Biller ScottChief Scientific Officer
Exercise / conversionCommon stock 2,146 $31.64 $67,899.44
Disclosure

SEC source: 0001209191-17-063884 · doc4.xml · nonDerivative · entry 1

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,410

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
December 01, 2017 Filed Jan 25, 2018 21:02 UTC Amendment
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 6,000 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-18-005355 · doc4a.xml · derivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,837

Underlying: Common stock · 6,000 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter.

F3 · balance_after: The original Form 4, filed on December 5, 2017, is being amended by this Form 4 amendment solely to correct the number of derivative securities beneficially owned following reported transaction.

Read SEC document
November 14, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 309 $60.46 $18,682.14
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 6

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 81,434

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.19 to $60.78. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

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November 14, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 309 $60.46 $18,682.14
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 5

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,394

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.19 to $60.78. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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November 14, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 691 $59.36 $41,017.76
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 4

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 81,743

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.05 to $59.71. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

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November 14, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 691 $59.36 $41,017.76
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 3

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,703

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.05 to $59.71. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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November 13, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 1,000 $62.07 $62,070.00
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 2

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 82,434

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.87 to $62.45. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3 · ownership.nature: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

Read SEC document
November 13, 2017 Filed Nov 15, 2017 22:43 UTC SaleCommon stock 1,000 $62.07 $62,070.00
Disclosure

SEC source: 0001209191-17-060967 · doc4.xml · nonDerivative · entry 1

Cantley Lewis Clayton Jr. · CIK 0001581950 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,394

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.87 to $62.45. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionStock option (right to buy) · Derivative 6,000 $0.00 Strike: $0.30 $0.00
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · derivative · entry 8

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,656

Underlying: Common stock · 6,000 shares

Expires 2019-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F8 · derivative.exercise_date: This option was granted on August 13, 2009. The shares underlying this option vest as to 25% of the shares on August 1, 2010, with the remaining 75% vesting in 36 equal monthly installments thereafter.

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November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 4,260 $63.32 $269,743.20
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · nonDerivative · entry 5

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $63.13 to $64.00. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 942 $64.64 $60,890.88
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · nonDerivative · entry 4

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,260

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $64.27 to $65.23. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 598 $65.42 $39,121.16
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · nonDerivative · entry 3

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,202

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $65.32 to $65.76. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
SaleCommon stock 200 $66.75 $13,350.00
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · nonDerivative · entry 2

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,800

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:00 UTC
Schenkein David PDirector · Chief Executive Officer
Exercise / conversionCommon stock 6,000 $0.30 $1,815.00
Disclosure

SEC source: 0001209191-17-059135 · doc4.xml · nonDerivative · entry 1

Schenkein David P · CIK 0001578200 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:01 UTC
Biller ScottChief Scientific Officer
Exercise / conversionStock option (right to buy) · Derivative 2,146 $0.00 Strike: $31.64 $0.00
Disclosure

SEC source: 0001209191-17-059138 · doc4.xml · derivative · entry 6

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,185

Underlying: Common stock · 2,146 shares

Expires 2024-03-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · derivative.exercise_date: This option was granted on March 5, 2014. The shares underlying this option vest as to 25% of the shares on March 5, 2015, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:01 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 946 $61.81 $58,472.26
Disclosure

SEC source: 0001209191-17-059138 · doc4.xml · nonDerivative · entry 5

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,264

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $61.36 to $62.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:01 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 900 $63.09 $56,781.00
Disclosure

SEC source: 0001209191-17-059138 · doc4.xml · nonDerivative · entry 4

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,210

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $62.57 to $63.49. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:01 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 200 $63.62 $12,724.00
Disclosure

SEC source: 0001209191-17-059138 · doc4.xml · nonDerivative · entry 3

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,110

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $63.60 to $63.63. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
November 01, 2017 Filed Nov 3, 2017 20:01 UTC
Biller ScottChief Scientific Officer
SaleCommon stock 100 $65.45 $6,545.00
Disclosure

SEC source: 0001209191-17-059138 · doc4.xml · nonDerivative · entry 2

Biller Scott · CIK 0001581956 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,310

F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.