Last 12 months
Inside the activity.
0 purchase rows · 39 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 2 |
| Dec 2025 | 0 | 6 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 21 |
| Apr 2026 | 0 | 7 |
| May 2026 | 0 | 0 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 1 |
| Aug 2026 | 0 | 1 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 4,154 | $0.00 Strike: $9.05 | $0.00 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · derivative · entry 7 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 4,154 shares Expires 2023-04-30 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F5 · derivative.exercise_date: This option was originally granted on April 30, 2013 for the purchase of 68,181 shares of common stock. The option vests as to 50% of the underlying shares upon the achievement of a performance milestone, and as to the remaining 50% of upon the achievement of a second performance milestone. The Company's board of directors determined that the first performance milestone was achieved on December 3, 2015, resulting in the vesting of this option as to 34,091 shares. On January 26, 2017, the Company's board of directors determined that the second performance milestone was achieved, resulting in the vesting of this option as to the remaining 34,090 shares. Read SEC document |
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 1,766 | $0.00 Strike: $0.47 | $0.00 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · derivative · entry 6 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 1,766 shares Expires 2020-12-06 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. F4 · derivative.exercise_date: This option was granted on December 7, 2010. The shares underlying this option vested as to 25% of the shares upon the achievement of a performance milestone, and as to the remaining 75% in 36 equal monthly installments thereafter. The performance criteria was met on June 23, 2015. Read SEC document |
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
SaleCommon stock | 9,000 | $65.00 | $585,000.00 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · nonDerivative · entry 4 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 26,511 F2 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 3,080 | $31.64 | $97,451.20 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · nonDerivative · entry 3 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 35,511 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 4,154 | $9.05 | $37,593.70 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · nonDerivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 32,431 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| February 27, 2019 Filed Mar 1, 2019 21:02 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 1,766 | $0.47 | $830.02 |
DisclosureSEC source: 0001209191-19-014933 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,277 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: This exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 16:21 UTC |
Alenson CarmanPrincipal Accounting Officer
|
GrantRestricted stock units · Derivative | 2,074 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-013515 · doc4.xml · derivative · entry 2 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,074 Underlying: Common stock · 2,074 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 16:21 UTC |
Alenson CarmanPrincipal Accounting Officer
|
GrantStock option (right to buy) · Derivative | 8,295 | $0.00 Strike: $58.86 | $0.00 |
DisclosureSEC source: 0001209191-19-013515 · doc4.xml · derivative · entry 1 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,295 Underlying: Common stock · 8,295 shares Expires 2029-02-22 F1 · derivative.exercise_date: This option was granted on February 22, 2019. The shares underlying this option vest as to 25% of the underlying shares on February 22, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:27 UTC |
Hirsch AndrewChief Financial Officer
|
GrantRestricted stock units · Derivative | 10,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-013536 · doc4.xml · derivative · entry 2 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:27 UTC |
Hirsch AndrewChief Financial Officer
|
GrantStock option (right to buy) · Derivative | 40,000 | $0.00 Strike: $58.86 | $0.00 |
DisclosureSEC source: 0001209191-19-013536 · doc4.xml · derivative · entry 1 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,000 Underlying: Common stock · 40,000 shares Expires 2029-02-22 F1 · derivative.exercise_date: This option was granted on February 22, 2019. The shares underlying this option vest as to 25% of the underlying shares on February 22, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:25 UTC |
Bowden ChristopherChief Medical Officer
|
GrantRestricted stock units · Derivative | 10,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-013531 · doc4.xml · derivative · entry 2 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:25 UTC |
Bowden ChristopherChief Medical Officer
|
GrantStock option (right to buy) · Derivative | 40,000 | $0.00 Strike: $58.86 | $0.00 |
DisclosureSEC source: 0001209191-19-013531 · doc4.xml · derivative · entry 1 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,000 Underlying: Common stock · 40,000 shares Expires 2029-02-22 F1 · derivative.exercise_date: This option was granted on February 22, 2019. The shares underlying this option vest as to 25% of the underlying shares on February 22, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:24 UTC |
Biller ScottChief Scientific Officer
|
GrantRestricted stock units · Derivative | 10,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-013525 · doc4.xml · derivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:24 UTC |
Biller ScottChief Scientific Officer
|
GrantStock option (right to buy) · Derivative | 40,000 | $0.00 Strike: $58.86 | $0.00 |
DisclosureSEC source: 0001209191-19-013525 · doc4.xml · derivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,000 Underlying: Common stock · 40,000 shares Expires 2029-02-22 F1 · derivative.exercise_date: This option was granted on February 22, 2019. The shares underlying this option vest as to 25% of the underlying shares on February 22, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:19 UTC |
Schenkein David PDirector
|
GrantRestricted stock units · Derivative | 8,324 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-013509 · doc4.xml · derivative · entry 2 Schenkein David P · CIK 0001578200 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,324 Underlying: Common stock · 8,324 shares Expires not disclosed F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. F3 · derivative.expiration_date: The restricted stock units were granted on February 22, 2019. Beginning on February 22, 2020, the shares underlying the restricted stock units will vest in three equal annual installments. Read SEC document |
| February 22, 2019 Filed Feb 26, 2019 21:19 UTC |
Schenkein David PDirector
|
GrantStock option (right to buy) · Derivative | 45,719 | $0.00 Strike: $58.86 | $0.00 |
DisclosureSEC source: 0001209191-19-013509 · doc4.xml · derivative · entry 1 Schenkein David P · CIK 0001578200 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 45,719 Underlying: Common stock · 45,719 shares Expires 2029-02-22 F1 · derivative.exercise_date: This option was granted on February 22, 2019. The shares underlying this option vest as to 25% of the underlying shares on February 22, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| February 21, 2019 Filed Feb 25, 2019 16:03 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Exercise / conversionRestricted stock units · Derivative | 3,300 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-012942 · doc4.xml · derivative · entry 3 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 3,300 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: All of the restricted stock units vested on February 21, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: All of the restricted stock units vested on February 21, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 21, 2019 Filed Feb 25, 2019 16:03 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Tax withholdingCommon stock | 1,016 | $56.33 | $57,231.28 |
DisclosureSEC source: 0001209191-19-012942 · doc4.xml · nonDerivative · entry 2 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,796 Read SEC document |
| February 21, 2019 Filed Feb 25, 2019 16:03 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Exercise / conversionCommon stock | 3,300 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-012942 · doc4.xml · nonDerivative · entry 1 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,812 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 16:01 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Tax withholdingCommon stock | 278 | $58.03 | $16,132.34 |
DisclosureSEC source: 0001209191-19-011483 · doc4.xml · nonDerivative · entry 3 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 512 Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 21:07 UTC |
Schenkein David PDirector
|
Tax withholdingCommon stock | 2,471 | $58.03 | $143,392.13 |
DisclosureSEC source: 0001209191-19-011498 · doc4.xml · nonDerivative · entry 2 Schenkein David P · CIK 0001578200 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 89,503 Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 21:04 UTC |
Bowden ChristopherChief Medical Officer
|
Tax withholdingCommon stock | 818 | $58.03 | $47,468.54 |
DisclosureSEC source: 0001209191-19-011489 · doc4.xml · nonDerivative · entry 2 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,195 Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 21:06 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Tax withholdingCommon stock | 1,040 | $58.03 | $60,351.20 |
DisclosureSEC source: 0001209191-19-011494 · doc4.xml · nonDerivative · entry 2 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,941 Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 21:05 UTC |
Hirsch AndrewChief Financial Officer
|
Tax withholdingCommon stock | 821 | $58.03 | $47,642.63 |
DisclosureSEC source: 0001209191-19-011491 · doc4.xml · nonDerivative · entry 2 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,374 Read SEC document |
| February 19, 2019 Filed Feb 20, 2019 21:03 UTC |
Biller ScottChief Scientific Officer
|
Tax withholdingCommon stock | 876 | $58.03 | $50,834.28 |
DisclosureSEC source: 0001209191-19-011486 · doc4.xml · nonDerivative · entry 2 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 26,511 Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 16:01 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Exercise / conversionRestricted stock units · Derivative | 790 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011483 · doc4.xml · derivative · entry 4 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 1,580 Underlying: Common stock · 790 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 16:01 UTC |
Alenson CarmanPrincipal Accounting Officer
|
Exercise / conversionCommon stock | 790 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011483 · doc4.xml · nonDerivative · entry 2 Alenson Carman · CIK 0001688865 · Principal Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 790 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:07 UTC |
Schenkein David PDirector
|
Exercise / conversionRestricted stock units · Derivative | 8,125 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011498 · doc4.xml · derivative · entry 5 Schenkein David P · CIK 0001578200 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 16,250 Underlying: Common stock · 8,125 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F4 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F4 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:07 UTC |
Schenkein David PDirector
|
Exercise / conversionCommon stock | 8,125 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011498 · doc4.xml · nonDerivative · entry 1 Schenkein David P · CIK 0001578200 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 91,974 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:04 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionRestricted stock unit · Derivative | 2,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011489 · doc4.xml · derivative · entry 3 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,500 Underlying: Common stock · 2,750 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:04 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionCommon stock | 2,750 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011489 · doc4.xml · nonDerivative · entry 1 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,013 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F2 · balance_after: Includes 34 shares purchased through the Company's employee stock purchase plan. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:06 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Exercise / conversionRestricted stock units · Derivative | 2,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011494 · doc4.xml · derivative · entry 3 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,500 Underlying: Common stock · 2,750 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:06 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Exercise / conversionCommon stock | 2,750 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011494 · doc4.xml · nonDerivative · entry 1 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 11,981 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:05 UTC |
Hirsch AndrewChief Financial Officer
|
Exercise / conversionRestricted stock units · Derivative | 2,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011491 · doc4.xml · derivative · entry 3 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,500 Underlying: Common stock · 2,750 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:05 UTC |
Hirsch AndrewChief Financial Officer
|
Exercise / conversionCommon stock | 2,750 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011491 · doc4.xml · nonDerivative · entry 1 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,195 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:03 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionRestricted stock units · Derivative | 2,750 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-011486 · doc4.xml · derivative · entry 4 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,500 Underlying: Common stock · 2,750 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F3 · derivative.expiration_date: The restricted stock units were granted on February 16, 2018. Beginning on February 16, 2019, the shares underlying the restricted stock units will vest in three equal annual installments. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| February 16, 2019 Filed Feb 20, 2019 21:03 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 2,750 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-011486 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 27,387 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| February 01, 2019 Filed Feb 5, 2019 21:28 UTC |
FOUSE JACQUALYN ADirector · Chief Executive Officer
|
GrantPerformance share units · Derivative | 42,695 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-007343 · doc4.xml · derivative · entry 2 FOUSE JACQUALYN A · CIK 0001405288 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 42,695 Underlying: Common stock · 42,695 shares Expires 2024-02-01 F2 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F3 · derivative.exercise_date: The performance share units vest if, during the five-year period beginning on February 1, 2019 and ending on February 1, 2024, the closing price of the issuer's common stock equals or exceeds $120 per share for at least 20 consecutive trading days at any time during such five-year period. F3 · derivative.expiration_date: The performance share units vest if, during the five-year period beginning on February 1, 2019 and ending on February 1, 2024, the closing price of the issuer's common stock equals or exceeds $120 per share for at least 20 consecutive trading days at any time during such five-year period. Read SEC document |
| February 01, 2019 Filed Feb 5, 2019 21:28 UTC |
FOUSE JACQUALYN ADirector · Chief Executive Officer
|
GrantStock option (right to buy) · Derivative | 350,346 | $0.00 Strike: $53.87 | $0.00 |
DisclosureSEC source: 0001209191-19-007343 · doc4.xml · derivative · entry 1 FOUSE JACQUALYN A · CIK 0001405288 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 350,346 Underlying: Common stock · 350,346 shares Expires 2029-01-31 F1 · derivative.exercise_date: This option was granted on February 1, 2019. The shares underlying this option vest as to 25% of the shares on February 1, 2020, with the remaining 75% vesting in 36 equal monthly installments thereafter. Read SEC document |
| January 22, 2019 Filed Jan 23, 2019 21:22 UTC |
Hirsch AndrewChief Financial Officer
|
Tax withholdingCommon stock | 4,555 | $52.82 | $240,595.10 |
DisclosureSEC source: 0001209191-19-004961 · doc4.xml · nonDerivative · entry 2 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,445 Read SEC document |
| January 22, 2019 Filed Jan 23, 2019 21:19 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Tax withholdingCommon stock | 5,769 | $52.82 | $304,718.58 |
DisclosureSEC source: 0001209191-19-004955 · doc4.xml · nonDerivative · entry 2 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 9,231 Read SEC document |
| January 22, 2019 Filed Jan 23, 2019 21:12 UTC |
Bowden ChristopherChief Medical Officer
|
Tax withholdingCommon stock | 1,960 | $52.82 | $103,527.20 |
DisclosureSEC source: 0001209191-19-004950 · doc4.xml · nonDerivative · entry 2 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,229 Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:22 UTC |
Hirsch AndrewChief Financial Officer
|
Exercise / conversionPerformance share unit · Derivative | 15,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-004961 · doc4.xml · derivative · entry 3 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 15,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The performance share units were originally granted on September 20, 2016. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: The performance share units were originally granted on September 20, 2016. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:22 UTC |
Hirsch AndrewChief Financial Officer
|
Exercise / conversionCommon stock | 15,000 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-004961 · doc4.xml · nonDerivative · entry 1 Hirsch Andrew · CIK 0001586707 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:19 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Exercise / conversionPerformance share unit · Derivative | 15,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-004955 · doc4.xml · derivative · entry 3 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 15,000 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The performance share units were originally granted on February 16, 2016. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: The performance share units were originally granted on February 16, 2016. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:19 UTC |
Hoerter Steven L.Chief Commercial Officer
|
Exercise / conversionCommon stock | 15,000 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-004955 · doc4.xml · nonDerivative · entry 1 Hoerter Steven L. · CIK 0001533451 · Chief Commercial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:12 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionPerformance share unit · Derivative | 6,265 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-19-004950 · doc4.xml · derivative · entry 3 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common stock · 6,265 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. F2 · derivative.exercise_date: The performance share units were originally granted on December 21, 2015. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. F2 · derivative.expiration_date: The performance share units were originally granted on December 21, 2015. The performance share units vest in full six months after the achievement of performance milestone. Performance milestone was achieved on July 20, 2018, and the performance share will vest in full on January 20, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested. Read SEC document |
| January 20, 2019 Filed Jan 23, 2019 21:12 UTC |
Bowden ChristopherChief Medical Officer
|
Exercise / conversionCommon stock | 6,265 | Not disclosed | Not disclosed |
DisclosureSEC source: 0001209191-19-004950 · doc4.xml · nonDerivative · entry 1 Bowden Christopher · CIK 0001608601 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,189 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Each performance share unit represents a contingent right to receive one share of the issuer's common stock. Read SEC document |
| December 21, 2018 Filed Dec 26, 2018 21:39 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionStock option (right to buy) · Derivative | 20,500 | $0.00 Strike: $2.34 | $0.00 |
DisclosureSEC source: 0001209191-18-064102 · doc4.xml · derivative · entry 3 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,218 Underlying: Common stock · 20,500 shares Expires 2022-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: This option was granted on April 6, 2012 for the purchase of 63,636 shares of common stock. The option vests as to 25% of the shares upon the achievement of a performance milestone, as to an additional 50% upon the achievement of a second performance milestone, and as to the remaining 25% on the first anniversary of the first date that both performance milestones were achieved. The performance criteria for the first performance milestone were met on March 18, 2013. The performance criteria for the second performance milestone were met on April 4, 2014, resulting in the vesting of the option as to 31,818 shares, and the remaining 15,909 shares vested on April 4, 2015. Read SEC document |
| December 21, 2018 Filed Dec 26, 2018 21:39 UTC |
Biller ScottChief Scientific Officer
|
Exercise / conversionCommon stock | 20,500 | $2.34 | $47,918.75 |
DisclosureSEC source: 0001209191-18-064102 · doc4.xml · nonDerivative · entry 1 Biller Scott · CIK 0001581956 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 24,637 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.