Khayal Tamer I

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 6

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,502

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F6 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $85.035 to $85.37, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,736

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $84.07 to $84.92, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 4

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,160

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $83.00 to $83.98, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,792

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $82.01 to $82.91, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,634

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $81.01 to $81.935, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-026492 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,502

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-021330 · ownership.xml · derivative · entry 4

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,690

Underlying: Common Stock · 18,690 shares

Expires 2034-02-23

F2 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares subject to the option each month following February 23, 2024 until the option is fully vested on February 23, 2028, subject to continued service.

SEC source: 0000950170-24-021330 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,502

F1 · shares: Consists of 12,127 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-018047 · ownership.xml · derivative · entry 10

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,746

Underlying: Common Stock · 250 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000950170-24-018047 · ownership.xml · nonDerivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F3 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-018047 · ownership.xml · nonDerivative · entry 4

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,625

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-018047 · ownership.xml · derivative · entry 9

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,996

Underlying: Common Stock · 1,714 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000950170-24-018047 · ownership.xml · derivative · entry 8

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,144 shares

Expires 2029-05-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F4 · derivative.exercise_date: The option is fully vested.

SEC source: 0000950170-24-018047 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.035, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-018047 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-018047 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,519

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-016560 · ownership.xml · derivative · entry 8

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,144

Underlying: Common Stock · 776 shares

Expires 2029-05-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · derivative.exercise_date: The option is fully vested.

SEC source: 0000950170-24-016560 · ownership.xml · nonDerivative · entry 4

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.005, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F4 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-016560 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,151

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-016560 · ownership.xml · derivative · entry 7

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,920

Underlying: Common Stock · 3,050 shares

Expires 2029-05-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · derivative.exercise_date: The option is fully vested.

SEC source: 0000950170-24-016560 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.09, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-016560 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,425

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-013458 · ownership.xml · derivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,970

Underlying: Common Stock · 736 shares

Expires 2029-05-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F4 · derivative.exercise_date: The option is fully vested.

SEC source: 0000950170-24-013458 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.01 to $90.185, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-013458 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,111

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-007427 · ownership.xml · derivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,706

Underlying: Common Stock · 2,330 shares

Expires 2029-05-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F4 · derivative.exercise_date: The option is fully vested.

SEC source: 0000950170-24-007427 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.23, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-007427 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,705

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-24-005420 · ownership.xml · derivative · entry 6

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,000

Underlying: Common Stock · 10,000 shares

Expires 2032-02-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F5 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on February 22, 2026.

SEC source: 0000950170-24-005420 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $81.045 to $81.16, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F4 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-24-005420 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,508

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $80.00 to $80.95, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-005420 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 24,375

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on September 6, 2023.

SEC source: 0000950170-23-033565 · ownership.xml · derivative · entry 7

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,539

Underlying: Common Stock · 1,461 shares

Expires 2031-02-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F5 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 24, 2021.

SEC source: 0000950170-23-033565 · ownership.xml · derivative · entry 6

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,710

Underlying: Common Stock · 3,539 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F4 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000950170-23-033565 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $95.00 to $95.60, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-23-033565 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,375

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

SEC source: 0000950170-23-033565 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,914

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

SEC source: 0000950170-23-033216 · ownership.xml · derivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,249

Underlying: Common Stock · 2,974 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F6 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000950170-23-033216 · ownership.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Khayal Family 2021 Irrevocable Trust

Disclosed balance after: 14,776

F4 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 12, 2022.

F5 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.23, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range

SEC source: 0000950170-23-033216 · ownership.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.23, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000950170-23-033216 · ownership.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,349

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

SEC source: 0000899243-23-011646 · doc4.xml · derivative · entry 9

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,223

Underlying: Common Stock · 2,026 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F8 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000899243-23-011646 · doc4.xml · derivative · entry 8

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,249

Underlying: Common Stock · 10,000 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F8 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 6

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Khayal Family 2021 Irrevocable Trust

Disclosed balance after: 17,001

F6 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 12, 2022.

F7 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.16, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,375

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $90.00 to $90.07, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F5 · balance_after: Includes 13,075 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 4

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,401

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $86.01 to $86.18, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 3

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,701

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $85.00 to $85.95, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 2

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,401

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

SEC source: 0000899243-23-011646 · doc4.xml · nonDerivative · entry 1

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,375

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan entered into on December 2, 2022.

SEC source: 0000899243-23-006757 · doc4.xml · derivative · entry 5

Khayal Tamer I · CIK 0001430462 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,249

Underlying: Common Stock · 10,000 shares

Expires 2030-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan.

F5 · derivative.exercise_date: The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, February 27, 2020.