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Decheng Capital Global Healthcare GP, LLC

Disclosed activity across 4 companies

Tapewire entity
74134
SEC CIK
0001949027

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Aardvark Therapeutics, Inc.AARD · Entity 659810% ownerFebruary 14, 2025February 19, 2025

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectBy Decheng Capital Global Life Sciences Fund IV, L.P.2,958,887 Last balance in matching sequence After 2025-02-14 transaction · row 3 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 1 · 2025-02-14 · Conversion · Acquired 2,333,887 · Balance 2,333,887

F1: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F2: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Row 3 · 2025-02-14 · Purchase · Acquired 625,000 · Balance 2,958,887

F2: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Decheng Capital Global Healthcare Fund (Master), LP958,412 Last balance in matching sequence After 2025-02-14 transaction · row 4 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 2 · 2025-02-14 · Conversion · Acquired 333,412 · Balance 333,412

F1: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F3: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Row 4 · 2025-02-14 · Purchase · Acquired 625,000 · Balance 958,412

F3: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Series C Convertible Preferred StockSEC Table II · derivative / convertible securityIndirectBy Decheng Capital Global Life Sciences Fund IV, L.P.0 Reported balance After 2025-02-14 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2025-02-14 · Conversion · Disposed 19,777,363 · Balance 0

F1: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F2: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Series C Convertible Preferred StockSEC Table II · derivative / convertible securityIndirectBy Decheng Capital Global Healthcare Fund (Master), LP0 Reported balance After 2025-02-14 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2025-02-14 · Conversion · Disposed 2,825,337 · Balance 0

F1: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F3: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F2: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

F3: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Past disclosures · reporting ended (3)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Section 16 reporting ended · disclosed 2024-05-21. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectSee Footnote0 Reported balance After 2024-05-18 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2024-05-18 · Other · Disposed 6,582,380 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the Agreement and Plan of Merger (the Merger Agreement), dated April 10, 2024, among Alpine Immune Sciences, Inc., a Delaware corporation (the Company), Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (Parent), and Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Parent (Merger Sub). Pursuant to the Merger Agreement, Merger Sub completed a tender offer for shares of the Companys Common Stock, par value $0.001 per share (Company Common Stock), effective May 18, 2024 (the Offer Closing), and thereafter merged with and into the Company (the Merger, and together with the Offer Closing, the Transactions), effective May 20, 2024 (the Effective Time), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

F2: (Continued from Footnote 1) In connection with the consummation of the Transactions, each share of the Company Common Stock was either (x) purchased at the Offer Closing for $65.00 in cash per share (the Offer Price), without interest thereon and subject to any applicable tax withholding or (y) automatically converted in the Merger at the Effective Time into the right to receive the Offer Price in cash, without interest thereon (the Merger Consideration), subject to any applicable tax withholding.

F3: These securities are owned directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Xiangmin Cui is the manager of Decheng Capital Management III (Cayman), LLC, the general partner of Fund III. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectSee Footnote0 Reported balance After 2024-05-18 transaction · row 2 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 2 · 2024-05-18 · Other · Disposed 1,735,544 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the Agreement and Plan of Merger (the Merger Agreement), dated April 10, 2024, among Alpine Immune Sciences, Inc., a Delaware corporation (the Company), Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (Parent), and Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Parent (Merger Sub). Pursuant to the Merger Agreement, Merger Sub completed a tender offer for shares of the Companys Common Stock, par value $0.001 per share (Company Common Stock), effective May 18, 2024 (the Offer Closing), and thereafter merged with and into the Company (the Merger, and together with the Offer Closing, the Transactions), effective May 20, 2024 (the Effective Time), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

F2: (Continued from Footnote 1) In connection with the consummation of the Transactions, each share of the Company Common Stock was either (x) purchased at the Offer Closing for $65.00 in cash per share (the Offer Price), without interest thereon and subject to any applicable tax withholding or (y) automatically converted in the Merger at the Effective Time into the right to receive the Offer Price in cash, without interest thereon (the Merger Consideration), subject to any applicable tax withholding.

F4: These securities are owned directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Decheng Capital Global Healthcare GP, LLC, the general partner of Healthcare. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.70 · Expires 2029-01-17Direct0 Reported balance After 2024-05-20 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2024-05-20 · Disposition to issuer · Disposed 7,650 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.62 · Expires 2030-01-01Direct0 Reported balance After 2024-05-20 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2024-05-20 · Disposition to issuer · Disposed 7,650 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $13.45 · Expires 2031-01-03Direct0 Reported balance After 2024-05-20 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2024-05-20 · Disposition to issuer · Disposed 7,650 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $13.89 · Expires 2032-01-02Direct0 Reported balance After 2024-05-20 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2024-05-20 · Disposition to issuer · Disposed 10,000 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $7.43 · Expires 2033-01-02Direct0 Reported balance After 2024-05-20 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2024-05-20 · Disposition to issuer · Disposed 10,000 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $19.00 · Expires 2034-01-01Direct0 Reported balance After 2024-05-20 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2024-05-20 · Disposition to issuer · Disposed 17,500 · Balance 0

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F9: 1/12th of the shares subject to the option become vested and exercisable on February 2, 2024 and 1/12 of the shares subject to the option shall vest monthly thereafter.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities disposed of pursuant to the Agreement and Plan of Merger (the Merger Agreement), dated April 10, 2024, among Alpine Immune Sciences, Inc., a Delaware corporation (the Company), Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (Parent), and Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Parent (Merger Sub). Pursuant to the Merger Agreement, Merger Sub completed a tender offer for shares of the Companys Common Stock, par value $0.001 per share (Company Common Stock), effective May 18, 2024 (the Offer Closing), and thereafter merged with and into the Company (the Merger, and together with the Offer Closing, the Transactions), effective May 20, 2024 (the Effective Time), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

F2: (Continued from Footnote 1) In connection with the consummation of the Transactions, each share of the Company Common Stock was either (x) purchased at the Offer Closing for $65.00 in cash per share (the Offer Price), without interest thereon and subject to any applicable tax withholding or (y) automatically converted in the Merger at the Effective Time into the right to receive the Offer Price in cash, without interest thereon (the Merger Consideration), subject to any applicable tax withholding.

F3: These securities are owned directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Xiangmin Cui is the manager of Decheng Capital Management III (Cayman), LLC, the general partner of Fund III. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

F4: These securities are owned directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Decheng Capital Global Healthcare GP, LLC, the general partner of Healthcare. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

F5: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F6: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

F7: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F9: 1/12th of the shares subject to the option become vested and exercisable on February 2, 2024 and 1/12 of the shares subject to the option shall vest monthly thereafter.

Section 16 reporting ended · disclosed 2025-10-21. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeIndirectBy Decheng Capital China Life Sciences USD Fund III, L.P.1,518,893 Last balance in matching sequence After 2025-10-17 transaction · row 2 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 1 · 2025-10-16 · Sale · Disposed 85,798 · Balance 1,564,406

F1: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.62 to $1.795 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2: These securities are held directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Decheng Capital Management III (Cayman), LLC ("GP III") is the general partner of Fund III. Dr. Cui is the manager of GP III. Each of Fund III, GP III and Dr. Cui may be deemed to beneficially own the securities held by Fund III. Each of GP III and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Row 2 · 2025-10-17 · Sale · Disposed 45,513 · Balance 1,518,893

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 to $1.80 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2: These securities are held directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Decheng Capital Management III (Cayman), LLC ("GP III") is the general partner of Fund III. Dr. Cui is the manager of GP III. Each of Fund III, GP III and Dr. Cui may be deemed to beneficially own the securities held by Fund III. Each of GP III and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Ordinary SharesSEC Table I · non-derivativeIndirectBy Decheng Capital China Life Sciences USD Fund II, L.P.1,617,409 Reported balance Holding disclosure · report date 2025-10-16 · row 3 Holding and transaction disclosures are not merged.
1 source row

Row 3 · Balance 1,617,409

F4: These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Ordinary SharesSEC Table I · non-derivativeIndirectBy Decheng Capital Global Healthcare Fund (Master), LP891,734 Reported balance Holding disclosure · report date 2025-10-16 · row 4 Holding and transaction disclosures are not merged.
1 source row

Row 4 · Balance 891,734

F5: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.62 to $1.795 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2: These securities are held directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Decheng Capital Management III (Cayman), LLC ("GP III") is the general partner of Fund III. Dr. Cui is the manager of GP III. Each of Fund III, GP III and Dr. Cui may be deemed to beneficially own the securities held by Fund III. Each of GP III and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 to $1.80 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4: These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

F5: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Section 16 reporting ended · disclosed 2024-04-09. Current position is not established by this disclosure.

Amendment: balances below belong to this corrected disclosure, not necessarily a complete replacement of earlier positions.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect4,958,810 Reported balance After 2024-01-29 transaction · row 1 Amendment: may correct only part of an earlier disclosure.
1 source row

Row 1 · 2024-01-29 · Purchase · Acquired 400,000 · Balance 4,958,810

F1: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
July 15, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 2,152 $2.28 $4,906.56
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 13

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 920,798

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 14, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 801 $2.29 $1,834.29
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 12

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 922,950

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 11, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 246 $2.29 $563.34
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 11

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 923,751

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 10, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 768 $2.28 $1,751.04
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 10

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 923,997

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 09, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 252 $2.27 $572.04
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 9

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 924,765

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 08, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 9,059 $2.29 $20,745.11
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 8

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 925,017

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 02, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 324 $2.42 $784.08
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 7

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 934,076

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
July 01, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 600 $2.43 $1,458.00
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 6

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 934,400

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
June 23, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 1,700 $3.09 $5,253.00
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 5

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital China Life Sciences USD Fund II, L.P.

Disclosed balance after: 1,617,409

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $3.06 to $3.19 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
June 20, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 225,217 $3.16 $711,685.72
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 4

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital China Life Sciences USD Fund II, L.P.

Disclosed balance after: 1,619,109

F4 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $3.05 to $3.27 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
June 20, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 60,000 $3.11 $186,600.00
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 3

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 935,000

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
June 18, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 59,253 $3.17 $187,832.01
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 2

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital China Life Sciences USD Fund II, L.P.

Disclosed balance after: 1,844,326

F2 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $3.10 to $3.34 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
June 17, 2025 Filed Aug 11, 2025 21:07 UTC BeyondSpring Inc. BYSI · Entity 7539 SaleOrdinary Shares 5,000 $3.23 $16,150.00
Disclosure

SEC source: 0001415889-25-021441 · form4-08112025_090812.xml · nonDerivative · entry 1

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital China Life Sciences USD Fund II, L.P. · CIK 0001650291 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 995,000

F1 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 ConversionSeries C Convertible Preferred Stock · Derivative 2,825,337 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · derivative · entry 6

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 0

Underlying: Common Stock · 333,412 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F1 · derivative.exercise_date: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F1 · derivative.expiration_date: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F3 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 ConversionSeries C Convertible Preferred Stock · Derivative 19,777,363 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · derivative · entry 5

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Life Sciences Fund IV, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 2,333,887 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F1 · derivative.exercise_date: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F1 · derivative.expiration_date: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F2 · ownership.nature: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 PurchaseCommon Stock 625,000 $16.00 $10,000,000.00
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · nonDerivative · entry 4

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 958,412

F3 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 PurchaseCommon Stock 625,000 $16.00 $10,000,000.00
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · nonDerivative · entry 3

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Life Sciences Fund IV, L.P.

Disclosed balance after: 2,958,887

F2 · ownership.nature: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 ConversionCommon Stock 333,412 Not disclosed Not disclosed
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · nonDerivative · entry 2

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 333,412

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F3 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
February 14, 2025 Filed Feb 19, 2025 22:44 UTC Aardvark Therapeutics, Inc. AARD · Entity 6598 ConversionCommon Stock 2,333,887 Not disclosed Not disclosed
Disclosure

SEC source: 0000950170-25-023409 · ownership.xml · nonDerivative · entry 1

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Life Sciences Fund IV, L.P.

Disclosed balance after: 2,333,887

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The Series C Convertible Preferred Stock of Aardvark Therapeutics, Inc. (the "Issuer") automatically converted on an 8.474-for-1 basis into shares of the Issuer's common stock ("Common Stock") immediately prior to the closing of the Issuer's initial public offering of its Common Stock. The Series C Convertible Preferred Stock had no expiration date.

F2 · ownership.nature: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 17,500 Not disclosed Strike: $19.00 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 8

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,500 shares

Expires 2034-01-01

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F9 · derivative.exercise_date: 1/12th of the shares subject to the option become vested and exercisable on February 2, 2024 and 1/12 of the shares subject to the option shall vest monthly thereafter.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 10,000 Not disclosed Strike: $7.43 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 7

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2033-01-02

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6 · derivative.exercise_date: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 10,000 Not disclosed Strike: $13.89 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 6

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2032-01-02

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6 · derivative.exercise_date: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 7,650 Not disclosed Strike: $13.45 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 5

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,650 shares

Expires 2031-01-03

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6 · derivative.exercise_date: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 7,650 Not disclosed Strike: $3.62 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 4

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,650 shares

Expires 2030-01-01

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6 · derivative.exercise_date: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Read SEC document
May 20, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 Disposition to issuerStock Option (Right to buy) · Derivative 7,650 Not disclosed Strike: $5.70 Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · derivative · entry 3

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,650 shares

Expires 2029-01-17

F5 · derivative.exercise_price: The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.

F7 · price: Pursuant to the Merger Agreement, as of immediately prior to the Effective Time, each option to purchase shares of Company Common Stock (a Company Option) that was then outstanding but not then vested or exercisable became immediately vested and exercisable in full. At the Effective Time, each Company Option that was then outstanding was automatically cancelled and, if such Company Option had a per share exercise price less than the Merger Consideration, the holder thereof became entitled to receive a cash payment, without interest thereon and subject to any applicable tax withholding, equal to the product obtained by multiplying (i) the total number of shares of Company Common Stock underlying such Company Option by (ii) the excess of the Merger Consideration over the exercise price per share such Company Option.

F8 · price: (Continued from Footnote 7) Any Company Option that had an exercise price per share that was equal to or exceeded the Merger Consideration was cancelled without any cash payment or other consideration being made in respect thereof.

F6 · derivative.exercise_date: The option to purchase shares of Company Common Stock (the Company Option) is fully vested and exercisable.

Read SEC document
May 18, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 OtherCommon Stock 1,735,544 Not disclosed Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · nonDerivative · entry 2

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F1 · price: This Form 4 reports securities disposed of pursuant to the Agreement and Plan of Merger (the Merger Agreement), dated April 10, 2024, among Alpine Immune Sciences, Inc., a Delaware corporation (the Company), Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (Parent), and Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Parent (Merger Sub). Pursuant to the Merger Agreement, Merger Sub completed a tender offer for shares of the Companys Common Stock, par value $0.001 per share (Company Common Stock), effective May 18, 2024 (the Offer Closing), and thereafter merged with and into the Company (the Merger, and together with the Offer Closing, the Transactions), effective May 20, 2024 (the Effective Time), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

F2 · price: (Continued from Footnote 1) In connection with the consummation of the Transactions, each share of the Company Common Stock was either (x) purchased at the Offer Closing for $65.00 in cash per share (the Offer Price), without interest thereon and subject to any applicable tax withholding or (y) automatically converted in the Merger at the Effective Time into the right to receive the Offer Price in cash, without interest thereon (the Merger Consideration), subject to any applicable tax withholding.

F4 · ownership.nature: These securities are owned directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Decheng Capital Global Healthcare GP, LLC, the general partner of Healthcare. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

Read SEC document
May 18, 2024 Filed May 21, 2024 00:08 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 OtherCommon Stock 6,582,380 Not disclosed Not disclosed
Disclosure

SEC source: 0001626199-24-000095 · wk-form4_1716250094.xml · nonDerivative · entry 1

Cui Xiangmin · CIK 0001487815 · Director · 10% owner

Decheng Capital China Life Sciences USD Fund III, L.P. · CIK 0001736814 · 10% owner

Decheng Capital Management III (Cayman), LLC · CIK 0001747821 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F1 · price: This Form 4 reports securities disposed of pursuant to the Agreement and Plan of Merger (the Merger Agreement), dated April 10, 2024, among Alpine Immune Sciences, Inc., a Delaware corporation (the Company), Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (Parent), and Adams Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Parent (Merger Sub). Pursuant to the Merger Agreement, Merger Sub completed a tender offer for shares of the Companys Common Stock, par value $0.001 per share (Company Common Stock), effective May 18, 2024 (the Offer Closing), and thereafter merged with and into the Company (the Merger, and together with the Offer Closing, the Transactions), effective May 20, 2024 (the Effective Time), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

F2 · price: (Continued from Footnote 1) In connection with the consummation of the Transactions, each share of the Company Common Stock was either (x) purchased at the Offer Closing for $65.00 in cash per share (the Offer Price), without interest thereon and subject to any applicable tax withholding or (y) automatically converted in the Merger at the Effective Time into the right to receive the Offer Price in cash, without interest thereon (the Merger Consideration), subject to any applicable tax withholding.

F3 · ownership.nature: These securities are owned directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Xiangmin Cui is the manager of Decheng Capital Management III (Cayman), LLC, the general partner of Fund III. Dr. Cui disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.

Read SEC document
January 29, 2024 Filed Jan 31, 2024 21:17 UTC CG Oncology, Inc. CGON · Entity 3735 ConversionSeries F Preferred Stock · Derivative 4,402,320 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-24-002062 · form4-01312024_090105.xml · derivative · entry 5

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 461,701 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
January 29, 2024 Filed Jan 31, 2024 21:17 UTC CG Oncology, Inc. CGON · Entity 3735 ConversionSeries E Preferred Stock · Derivative 21,547,685 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-24-002062 · form4-01312024_090105.xml · derivative · entry 4

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,259,851 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
January 29, 2024 Filed Jan 31, 2024 21:17 UTC CG Oncology, Inc. CGON · Entity 3735 ConversionSeries C Preferred Stock · Derivative 8,644,891 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-24-002062 · form4-01312024_090105.xml · derivative · entry 3

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 906,648 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
January 29, 2024 Filed Jan 31, 2024 21:17 UTC CG Oncology, Inc. CGON · Entity 3735 PurchaseCommon Stock 400,000 $19.00 $7,600,000.00
Disclosure

SEC source: 0001415889-24-002062 · form4-01312024_090105.xml · nonDerivative · entry 2

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Decheng Capital Global Healthcare Fund (Master), LP

Disclosed balance after: 400,000

F3 · ownership.nature: These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

Read SEC document
January 29, 2024 Filed Jan 31, 2024 21:17 UTC CG Oncology, Inc. CGON · Entity 3735 ConversionCommon Stock 3,628,198 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-24-002062 · form4-01312024_090105.xml · nonDerivative · entry 1

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,558,812

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of the Issuer's preferred stock is convertible into shares of the Issuer's common stock at the holder's election and has no expiration date. The preferred stock automatically converted into common stock upon the closing of the Issuer's initial public offering.

F2 · ownership.direct: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

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January 29, 2024 Filed Apr 9, 2024 23:08 UTC Amendment CG Oncology, Inc. CGON · Entity 3735 PurchaseCommon Stock 400,000 $19.00 $7,600,000.00
Disclosure

SEC source: 0001415889-24-010609 · form4a-04092024_110416.xml · nonDerivative · entry 1

Decheng Capital Global Life Sciences Fund IV, L.P. · CIK 0001834150 · 10% owner

Decheng Capital Management IV (Cayman), LLC · CIK 0001843384 · 10% owner

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Cui Xiangmin · CIK 0001487815 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,958,810

F1 · ownership.direct: These securities are held directly by Decheng Capital Global Life Sciences Fund IV, L.P. ("Fund IV"). Decheng Capital Management IV (Cayman), LLC ("GP IV") is the general partner of Fund IV. Xiangmin Cui is the manager of GP IV. Each of Fund IV, GP IV and Dr. Cui may be deemed to beneficially own the securities held by Fund IV. Each of GP IV and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.

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November 09, 2023 Filed Nov 14, 2023 17:36 UTC ALPINE IMMUNE SCIENCES, INC. ALPN · Entity 90802 PurchaseCommon Stock 375,000 $12.50 $4,687,500.00
Disclosure

SEC source: 0001209191-23-055210 · doc4.xml · nonDerivative · entry 1

Decheng Capital Global Healthcare Fund (Master), LP · CIK 0001949026 · 10% owner

Decheng Capital Global Healthcare GP, LLC · CIK 0001949027 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,735,544

F1 · ownership.direct: The reportable securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Xiangmin Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Each of Healthcare, Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Healthcare GP disclaims beneficial ownership of these securities, except to the extent of its pecuniary interest therein. Dr. Cui is a director of the Issuer and files separate Section 16 reports.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.