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person · Reporting owner

MacLean Michael F

Disclosed activity across 5 companies

Tapewire entity
45936
SEC CIK
0001383731

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AKCEA THERAPEUTICS, INC.AKCA · Entity 145982Chief Financial OfficerJanuary 15, 2020January 16, 2020
Camp4 Therapeutics CorpCAMP · Entity 1161DirectorApril 01, 2026April 03, 2026
Research Alliance Corp IIIRACC · Entity 6369DirectorMay 19, 2026May 19, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AKCEA THERAPEUTICS, INC.

Report date January 15, 2020 · Filed January 16, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect48,000 Reported balance After 2020-01-15 transaction · row 1
1 source row

Row 1 · 2020-01-15 · Grant · Acquired 28,000 · Balance 48,000

F1: Represents restricted stock unit award granted under the Issuer's 2015 Equity Incentive Plan.

Filing footnotes · ownership attribution and instrument terms

F1: Represents restricted stock unit award granted under the Issuer's 2015 Equity Incentive Plan.

Camp4 Therapeutics Corp

Report date April 01, 2026 · Filed April 03, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.46 · Expires 2036-03-31Direct56,000 Reported balance After 2026-04-01 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-04-01 · Grant · Acquired 56,000 · Balance 56,000

F1: The shares underlying the option vest in equal monthly installments over a period of three years commencing from the date of grant.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying the option vest in equal monthly installments over a period of three years commencing from the date of grant.

Research Alliance Corp III

Report date May 19, 2026 · Filed May 19, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Class B Ordinary SharesSEC Table II · derivative / convertible securityDirectNot disclosed Reported balance Holding disclosure · report date 2026-05-19 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: Class B Ordinary Shares have no expiration date and will automatically convert into Class A Ordinary Shares of the Issuer at the time of the Issuer's initial business combination on a one-for-one basis (subject to adjustment for sub-divisions, share dividends, reorganizations, recapitalizations and the like), or at any time prior thereto at the option of the holder on a one-for-one basis, subject to adjustment pursuant to certain anti-dilution rights.

Filing footnotes · ownership attribution and instrument terms

F1: Class B Ordinary Shares have no expiration date and will automatically convert into Class A Ordinary Shares of the Issuer at the time of the Issuer's initial business combination on a one-for-one basis (subject to adjustment for sub-divisions, share dividends, reorganizations, recapitalizations and the like), or at any time prior thereto at the option of the holder on a one-for-one basis, subject to adjustment pursuant to certain anti-dilution rights.

Past disclosures · reporting ended (2)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Avidity Biosciences, Inc.

Report date February 27, 2026 · Filed February 27, 2026

Section 16 reporting ended · disclosed 2026-02-27. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2026-02-27 transaction · row 1
1 source row

Row 1 · 2026-02-27 · Disposition to issuer · Disposed 133,977 · Balance 0

F1: The reported securities represent shares of Common Stock (inclusive of shares of Common Stock issuable upon settlement of previously reported restricted stock units) disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of October 25, 2025 (the "Merger Agreement"), among Novartis AG ("Novartis"), Ajax Acquisition Sub, Inc., an indirect wholly owned subsidiary of Novartis, and the Issuer.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $22.34 · Expires 2031-02-01Direct0 Reported balance After 2026-02-27 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-02-27 · Disposition to issuer · Disposed 92,000 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $14.22 · Expires 2032-01-20Direct0 Reported balance After 2026-02-27 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-02-27 · Disposition to issuer · Disposed 131,250 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $22.47 · Expires 2033-01-19Direct0 Reported balance After 2026-02-27 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-02-27 · Disposition to issuer · Disposed 148,000 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.57 · Expires 2033-09-10Direct0 Reported balance After 2026-02-27 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-02-27 · Disposition to issuer · Disposed 60,125 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $10.16 · Expires 2034-01-19Direct0 Reported balance After 2026-02-27 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-02-27 · Disposition to issuer · Disposed 106,000 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $31.42 · Expires 2035-01-05Direct0 Reported balance After 2026-02-27 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-02-27 · Disposition to issuer · Disposed 50,000 · Balance 0

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Filing footnotes · ownership attribution and instrument terms

F1: The reported securities represent shares of Common Stock (inclusive of shares of Common Stock issuable upon settlement of previously reported restricted stock units) disposed of pursuant to the terms of the Agreement and Plan of Merger, dated as of October 25, 2025 (the "Merger Agreement"), among Novartis AG ("Novartis"), Ajax Acquisition Sub, Inc., an indirect wholly owned subsidiary of Novartis, and the Issuer.

F2: The reported Options were disposed of, pursuant to the Merger Agreement, in exchange for a cash payment equal to the excess of the merger consideration of $72.00 over the exercise price.

Verve Therapeutics, Inc.

Report date July 25, 2025 · Filed July 28, 2025

Section 16 reporting ended · disclosed 2025-07-28. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.02Direct0 Reported balance After 2025-07-25 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2025-07-25 · Disposition to issuer · Disposed 136,139 · Balance 0

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the applicable exercise price per share underlying such

F2: (continued from footnote 1) Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.73Direct0 Reported balance After 2025-07-25 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2025-07-25 · Disposition to issuer · Disposed 42,200 · Balance 0

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the applicable exercise price per share underlying such

F2: (continued from footnote 1) Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Filing footnotes · ownership attribution and instrument terms

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the applicable exercise price per share underlying such

F2: (continued from footnote 1) Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
January 20, 2023 Filed Jan 25, 2023 02:06 UTC Avidity Biosciences, Inc. RNA · Entity 11854 GrantStock Option (Right to Buy) · Derivative 148,000 $0.00 Strike: $22.47 $0.00
Disclosure

SEC source: 0001209191-23-004756 · doc4.xml · derivative · entry 2

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,000

Underlying: Common Stock · 148,000 shares

Expires 2033-01-19

F3 · derivative.exercise_date: 1/48th of the total number of shares subject to the options shall vest on each monthly anniversary of January 20, 2023 (the "Vesting Commencement Date"), subject to the Reporting Person's continuous service to the Issuer on each such vesting date, so that the options shall be fully vested on the fourth anniversary of the Vesting Commencement Date.

Read SEC document
January 20, 2023 Filed Jan 25, 2023 02:06 UTC Avidity Biosciences, Inc. RNA · Entity 11854 GrantCommon Stock 18,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-004756 · doc4.xml · nonDerivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,852

F1 · shares: Represents restricted stock units (RSUs). Each RSU represents a contingent right to receive one share of the Issuer's common stock. The RSUs shall vest in four equal installments on the first four anniversaries of January 20, 2023, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

F2 · balance_after: Includes 3,352 shares previously acquired by the Reporting Person under the Avidity Biosciences, Inc. 2020 Employee Stock Purchase Plan.

Read SEC document
June 09, 2022 Filed Jun 13, 2022 17:00 UTC Verve Therapeutics, Inc. VERV · Entity 11259 GrantStock Option (right to buy) · Derivative 15,500 $0.00 Strike: $14.04 $0.00
Disclosure

SEC source: 0001209191-22-036367 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,500

Underlying: Common Stock · 15,500 shares

Expires 2032-06-08

F1 · derivative.exercise_date: This stock option was issued pursuant to the 2021 Stock Incentive Plan of Verve Therapeutics, Inc. in accordance with its director compensation program. The vesting commencement date (the "Vesting Commencement Date") of the options is the grant date. All of the shares of common stock underlying the option vest upon the earlier of the one-year anniversary of the Vesting Commencement Date or immediately prior to the first annual meeting of stockholders occurring after the grant date, in each case subject to the Reporting Person's continued service as a director.

Read SEC document
January 21, 2022 Filed Mar 16, 2022 01:18 UTC Avidity Biosciences, Inc. RNA · Entity 11854 GrantStock Option (Right to Buy) · Derivative 131,250 $0.00 Strike: $14.22 $0.00
Disclosure

SEC source: 0001209191-22-019046 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,250

Underlying: Common Stock · 131,250 shares

Expires 2032-01-20

F1 · derivative.exercise_date: 1/48th of the total number of shares subject to the options shall vest on each monthly anniversary of January 3, 2022 (the "Vesting Commencement Date"), subject to the Reporting Person's continuous service to the Issuer on each such vesting date, so that the options shall be fully vested on the fourth anniversary of the Vesting Commencement Date.

Read SEC document
June 17, 2021 Filed Jun 21, 2021 18:21 UTC Verve Therapeutics, Inc. VERV · Entity 11259 GrantStock Option (right to buy) · Derivative 47,664 $0.00 Strike: $19.00 $0.00
Disclosure

SEC source: 0000899243-21-025072 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,664

Underlying: Common Stock · 47,664 shares

Expires 2031-06-16

F1 · derivative.exercise_date: The option was granted on June 17, 2021. The shares underlying the option vest quarterly over four years in 16 equal installments following May 20, 2021.

Read SEC document
February 02, 2021 Filed Feb 4, 2021 22:06 UTC Avidity Biosciences, Inc. RNA · Entity 11854 GrantStock Option (Right to Buy) · Derivative 92,000 $0.00 Strike: $22.34 $0.00
Disclosure

SEC source: 0001209191-21-007792 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,000

Underlying: Common Stock · 92,000 shares

Expires 2031-02-01

F1 · derivative.exercise_date: 1/48th of the total number of shares subject to the options shall vest on each monthly anniversary of January 1, 2021 (the "Vesting Commencement Date"), subject to the Reporting Person's continuous service to the Issuer on each such vesting date, so that the options shall be fully vested on the fourth anniversary of the Vesting Commencement Date.

Read SEC document
January 15, 2020 Filed Jan 16, 2020 23:03 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantCommon Stock 28,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-20-003752 · doc4.xml · nonDerivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,000

F1 · shares: Represents restricted stock unit award granted under the Issuer's 2015 Equity Incentive Plan.

Read SEC document
January 02, 2020 Filed Jan 3, 2020 22:21 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantStock Option (right to buy) · Derivative 57,000 $0.00 Strike: $16.99 $0.00
Disclosure

SEC source: 0001209191-20-001230 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,000

Underlying: Common Stock · 57,000 shares

Expires 2030-01-01

F1 · derivative.exercise_date: The shares vest as follows: 1/4th of the shares vest one year after January 2, 2020; 1/48th of the shares vest monthly thereafter over the next three years.

Read SEC document
September 19, 2019 Filed Sep 23, 2019 21:24 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantCommon Stock 20,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-050482 · doc4.xml · nonDerivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Read SEC document
January 02, 2019 Filed Jan 4, 2019 22:27 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantStock Option (right to buy) · Derivative 83,000 $0.00 Strike: $30.73 $0.00
Disclosure

SEC source: 0001209191-19-002133 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 83,000

Underlying: Common Stock · 83,000 shares

Expires 2029-01-01

F1 · derivative.exercise_date: The shares vest as follows: 1/4th of the shares vest one year after January 2, 2019; 1/48th of the shares vest monthly thereafter over the next three years.

Read SEC document
January 02, 2018 Filed Jan 4, 2018 23:57 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantStock Option (right to buy) · Derivative 30,000 $0.00 Strike: $17.38 $0.00
Disclosure

SEC source: 0001209191-18-002229 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2028-01-01

F1 · derivative.exercise_date: The shares vest as follows: 1/4th of the shares vest one year after January 2, 2018; 1/48th of the shares vest monthly thereafter over the next three years.

Read SEC document
August 31, 2017 Filed Sep 5, 2017 20:36 UTC AKCEA THERAPEUTICS, INC. AKCA · Entity 145982 GrantStock Option (right to buy) · Derivative 332,708 $0.00 Strike: $18.65 $0.00
Disclosure

SEC source: 0001209191-17-051325 · doc4.xml · derivative · entry 1

MacLean Michael F · CIK 0001383731 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 332,708

Underlying: Common Stock · 332,708 shares

Expires 2027-08-30

F1 · derivative.exercise_date: The shares vest as follows: 1/4th of the shares vest one year after August 31, 2017; 1/48th of the shares vest monthly thereafter over the next three years.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.