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person · Reporting owner

McCain Tracey L

Disclosed activity across 3 companies

Tapewire entity
42414
SEC CIK
0001683600

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Kiniksa Pharmaceuticals International, plcKNSA · Entity 1954DirectorMay 29, 2026June 02, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Kiniksa Pharmaceuticals International, plc

Report date May 29, 2026 · Filed June 02, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Class A Ordinary ShareSEC Table I · non-derivativeDirect15,345 Reported balance After 2026-05-29 transaction · row 1
1 source row

Row 1 · 2026-05-29 · Exercise / conversion · Acquired 2,799 · Balance 15,345

F1: Each Restricted Share Unit (RSU) represents a contingent right to receive one Class A Ordinary Share of the Issuer.

Share OptionSEC Table II · derivative / convertible security · Conversion / exercise price $48.38 · Expires 2036-05-28Direct12,158 Reported balance After 2026-05-29 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-05-29 · Grant · Acquired 12,158 · Balance 12,158

F2: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of the grant with the final installment vesting on the earlier of a) the anniversary of the date of the grant and b) the date of the Issuer's annual meeting of shareholders in the following year. The date of the grant is May 29, 2026.

Restricted Share UnitsSEC Table II · derivative / convertible securityDirect2,026 Reported balance After 2026-05-29 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-05-29 · Grant · Acquired 2,026 · Balance 2,026

F1: Each Restricted Share Unit (RSU) represents a contingent right to receive one Class A Ordinary Share of the Issuer.

F3: The RSUs vest in their entirety on the earlier of a) the anniversary of the date of the grant and b) the date of the Issuer's annual meeting of shareholders in the following year. The date of the grant is May 29, 2026.

Restricted Share UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-05-29 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-05-29 · Exercise / conversion · Disposed 2,799 · Balance 0

F1: Each Restricted Share Unit (RSU) represents a contingent right to receive one Class A Ordinary Share of the Issuer.

F4: The RSUs vested in a single installment on May 29, 2026; there was no expiration date for the RSUs.

Filing footnotes · ownership attribution and instrument terms

F1: Each Restricted Share Unit (RSU) represents a contingent right to receive one Class A Ordinary Share of the Issuer.

F2: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of the grant with the final installment vesting on the earlier of a) the anniversary of the date of the grant and b) the date of the Issuer's annual meeting of shareholders in the following year. The date of the grant is May 29, 2026.

F3: The RSUs vest in their entirety on the earlier of a) the anniversary of the date of the grant and b) the date of the Issuer's annual meeting of shareholders in the following year. The date of the grant is May 29, 2026.

F4: The RSUs vested in a single installment on May 29, 2026; there was no expiration date for the RSUs.

Past disclosures · reporting ended (2)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Blueprint Medicines Corp

Report date July 17, 2025 · Filed July 21, 2025

Section 16 reporting ended · disclosed 2025-07-21. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect88,195 Reported balance After 2025-07-17 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2025-07-17 · Grant · Acquired 21,353 · Balance 88,195

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F3: Represents shares previously granted to the Reporting Person subject to performance-based vesting conditions ("PSUs"), for which the performance conditions associated with such PSUs had not yet occurred. As of the Effective Time, each PSU was deemed earned based on the greater of target and actual performance as of the Effective Time. Pursuant to the terms of the Merger Agreement, at the Effective Time, each PSU was cancelled and automatically converted into the right to receive the Offer Consideration, except that fifty percent of such PSUs that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price, plus one CVR for each share underlying such portion of the award.

F4: Includes 259 shares that were previously acquired under the Issuer's employee stock purchase plan.

Common StockSEC Table I · non-derivativeDirect37,092 Reported balance After 2025-07-17 transaction · row 2 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 2 · 2025-07-17 · Disposition to issuer · Disposed 51,103 · Balance 37,092

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F3: Represents shares previously granted to the Reporting Person subject to performance-based vesting conditions ("PSUs"), for which the performance conditions associated with such PSUs had not yet occurred. As of the Effective Time, each PSU was deemed earned based on the greater of target and actual performance as of the Effective Time. Pursuant to the terms of the Merger Agreement, at the Effective Time, each PSU was cancelled and automatically converted into the right to receive the Offer Consideration, except that fifty percent of such PSUs that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price, plus one CVR for each share underlying such portion of the award.

F5: Pursuant to the terms of the Merger Agreement, at the Effective Time, each outstanding restricted stock unit ("RSU"), whether vested or unvested, was cancelled and automatically converted into the right to receive the Offer Consideration, except that fifty percent of such RSUs that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price, plus one CVR for each share underlying such portion of the award.

Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2025-07-17 transaction · row 3 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 3 · 2025-07-17 · Other · Disposed 37,092 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F6: Pursuant to the terms of the Merger Agreement, at the Effective Time, each share of Common Stock held by the Reporting Person was tendered in exchange for the Offer Consideration.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $28.36Direct0 Reported balance After 2025-07-17 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2025-07-17 · Disposition to issuer · Disposed 55,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $36.05Direct0 Reported balance After 2025-07-17 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2025-07-17 · Disposition to issuer · Disposed 5,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $81.44Direct0 Reported balance After 2025-07-17 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2025-07-17 · Disposition to issuer · Disposed 39,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $86.60Direct0 Reported balance After 2025-07-17 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2025-07-17 · Disposition to issuer · Disposed 29,900 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $54.13Direct0 Reported balance After 2025-07-17 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2025-07-17 · Disposition to issuer · Disposed 28,500 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $100.13Direct0 Reported balance After 2025-07-17 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2025-07-17 · Disposition to issuer · Disposed 26,125 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $61.31Direct0 Reported balance After 2025-07-17 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2025-07-17 · Disposition to issuer · Disposed 25,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $43.15Direct0 Reported balance After 2025-07-17 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2025-07-17 · Disposition to issuer · Disposed 25,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $95.12Direct0 Reported balance After 2025-07-17 transaction · row 12 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 12 · 2025-07-17 · Disposition to issuer · Disposed 25,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $96.57Direct0 Reported balance After 2025-07-17 transaction · row 13 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 13 · 2025-07-17 · Disposition to issuer · Disposed 22,000 · Balance 0

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities transacted pursuant to the Agreement and Plan of Merger (the "Merger Agreement") by and among the Issuer, SANOFI, a French societe anonyme ("Parent"), Aventis Inc., a Pennsylvania corporation and wholly owned subsidiary of Parent ("Aventis"), and Rothko Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Aventis ("Purchaser").

F2: Pursuant to the Merger Agreement, Purchaser completed a tender offer to acquire all of the issued and outstanding shares of common stock of the Issuer, par value $0.001 per share (the "Common Stock"), for (i) $129.00 per share, without interest (the "Cash Offer Price"), plus (ii) one (1) contractual contingent value right per share, representing the right to receive contingent payments in cash, without interest, upon the achievement of certain milestones (each a "CVR" and together with the Cash Offer Price, the "Offer Consideration"). On July 17, 2025 (the "Effective Time"), Purchaser merged with and into the Issuer, with the Issuer surviving as an indirect wholly owned subsidiary of Parent.

F3: Represents shares previously granted to the Reporting Person subject to performance-based vesting conditions ("PSUs"), for which the performance conditions associated with such PSUs had not yet occurred. As of the Effective Time, each PSU was deemed earned based on the greater of target and actual performance as of the Effective Time. Pursuant to the terms of the Merger Agreement, at the Effective Time, each PSU was cancelled and automatically converted into the right to receive the Offer Consideration, except that fifty percent of such PSUs that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price, plus one CVR for each share underlying such portion of the award.

F4: Includes 259 shares that were previously acquired under the Issuer's employee stock purchase plan.

F5: Pursuant to the terms of the Merger Agreement, at the Effective Time, each outstanding restricted stock unit ("RSU"), whether vested or unvested, was cancelled and automatically converted into the right to receive the Offer Consideration, except that fifty percent of such RSUs that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price, plus one CVR for each share underlying such portion of the award.

F6: Pursuant to the terms of the Merger Agreement, at the Effective Time, each share of Common Stock held by the Reporting Person was tendered in exchange for the Offer Consideration.

F7: Pursuant to the terms of the Merger Agreement, at the Effective Time, each stock option that was outstanding, whether vested or unvested, immediately prior to the Effective Time became fully vested and was cancelled and converted into the right to receive for each share subject to such stock option (i) the Cash Offer Price (less the applicable exercise price per share subject to such option) and (ii) one (1) CVR (in each case, without interest and less applicable tax withholdings), except that fifty percent of such options that were issued in calendar year 2025 were converted into cash-based awards subject to continued vesting as described in the Merger Agreement based on the Cash Offer Price (less the applicable exercise price per share subject to such option), plus one CVR for each share underlying such portion of the option.

ImmunoGen, Inc.

Report date February 12, 2024 · Filed February 12, 2024

Section 16 reporting ended · disclosed 2024-02-12. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Restricted Stock UnitSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2024-02-12 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2024-02-12 · Disposition to issuer · Disposed 13,090 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated November 30, 2023, by and among the Issuer, AbbVie Inc., a Delaware corporation ("AbbVie"), Athene Subsidiary LLC, a Delaware limited liability company and wholly owned subsidiary of AbbVie ("Intermediate Sub"), and Athene Merger Sub Inc., a Massachusetts corporation and wholly owned subsidiary of Intermediate Sub ("Purchaser"), pursuant to which Purchaser merged with and into the Issuer with the Issuer continuing as the surviving corporation (the "Merger").

F2: At the effective time of the Merger (the "Effective Time"), each restricted stock unit ("RSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such RSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of common stock, par value $.01 per share, of the Issuer ("Common Stock") subject to such RSU immediately prior to the Effective Time, multiplied by (ii) $31.26, without interest (the "Merger Consideration").

Deferred Share UnitSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2024-02-12 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2024-02-12 · Disposition to issuer · Disposed 50,303 · Balance 0

F3: Pursuant to the Merger Agreement, at the Effective Time, each deferred share unit ("DSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such DSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such DSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.72 · Expires 2033-06-14Direct0 Reported balance After 2024-02-12 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2024-02-12 · Disposition to issuer · Disposed 19,597 · Balance 0

F4: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.37 · Expires 2032-06-15Direct0 Reported balance After 2024-02-12 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2024-02-12 · Disposition to issuer · Disposed 25,556 · Balance 0

F4: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.68 · Expires 2031-11-15Direct0 Reported balance After 2024-02-12 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2024-02-12 · Disposition to issuer · Disposed 44,000 · Balance 0

F4: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated November 30, 2023, by and among the Issuer, AbbVie Inc., a Delaware corporation ("AbbVie"), Athene Subsidiary LLC, a Delaware limited liability company and wholly owned subsidiary of AbbVie ("Intermediate Sub"), and Athene Merger Sub Inc., a Massachusetts corporation and wholly owned subsidiary of Intermediate Sub ("Purchaser"), pursuant to which Purchaser merged with and into the Issuer with the Issuer continuing as the surviving corporation (the "Merger").

F2: At the effective time of the Merger (the "Effective Time"), each restricted stock unit ("RSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such RSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of common stock, par value $.01 per share, of the Issuer ("Common Stock") subject to such RSU immediately prior to the Effective Time, multiplied by (ii) $31.26, without interest (the "Merger Consideration").

F3: Pursuant to the Merger Agreement, at the Effective Time, each deferred share unit ("DSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such DSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such DSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

F4: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
June 30, 2022 Filed Jul 5, 2022 16:34 UTC ImmunoGen, Inc. IMGN · Entity 94428 GrantDeferred Share Unit · Derivative 3,055 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-22-007342 · form4-07052022_010742.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,655

Underlying: Common Stock · 3,055 shares

Expires not disclosed

F1 · derivative.exercise_price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F1 · price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F2 · derivative.exercise_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

F3 · derivative.exercise_date: The deferred share units vest upon issuance.

F2 · derivative.expiration_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

Read SEC document
June 29, 2022 Filed Jun 30, 2022 20:21 UTC Kiniksa Pharmaceuticals International, plc KNSA · Entity 1954 GrantRestricted Share Units · Derivative 5,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-007107 · form4-06302022_010657.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Class A Common Shares · 5,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each Restricted Share Unit (RSU) represents a contingent right to receive one Class A Common Share of the Issuer.

F3 · derivative.exercise_date: The RSUs vest in their entirety on the first anniversary of the date of grant, June 29, 2022.

F3 · derivative.expiration_date: The RSUs vest in their entirety on the first anniversary of the date of grant, June 29, 2022.

Read SEC document
June 29, 2022 Filed Jun 30, 2022 20:21 UTC Kiniksa Pharmaceuticals International, plc KNSA · Entity 1954 GrantShare Option · Derivative 30,000 $0.00 Strike: $9.88 $0.00
Disclosure

SEC source: 0001415889-22-007107 · form4-06302022_010657.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Class A Common Shares · 30,000 shares

Expires 2032-06-28

F1 · derivative.exercise_date: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of grant. The date of grant is June 29, 2022.

Read SEC document
June 15, 2022 Filed Jun 17, 2022 16:07 UTC ImmunoGen, Inc. IMGN · Entity 94428 GrantStock Option (right to buy) · Derivative 25,556 $3.37 Strike: $3.37 $86,123.72
Disclosure

SEC source: 0001415889-22-006699 · form4-06172022_010652.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,556

Underlying: Common Stock · 25,556 shares

Expires 2032-06-15

F4 · derivative.exercise_date: Exercisable as to 6,389 shares on each of 9/1/22, 12/1/22, 3/1/23, and 6/1/23, contingent upon the individual remaining a director as of each vesting date.

Read SEC document
June 15, 2022 Filed Jun 17, 2022 16:07 UTC ImmunoGen, Inc. IMGN · Entity 94428 GrantDeferred Share Unit · Derivative 8,712 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006699 · form4-06172022_010652.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,600

Underlying: Common Stock · 8,712 shares

Expires not disclosed

F1 · derivative.exercise_price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F1 · price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F2 · derivative.exercise_date: The deferred share units vest ratably over a one-year period in quarterly increments beginning on 9/1/2022, contingent upon the individual remaining a director as of each vesting date.

F3 · derivative.exercise_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

F3 · derivative.expiration_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

F3 · derivative.underlying: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

Read SEC document
March 31, 2022 Filed Apr 4, 2022 16:13 UTC ImmunoGen, Inc. IMGN · Entity 94428 GrantDeferred Share Unit · Derivative 2,888 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001179110-22-002537 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,888

Underlying: Common Stock · 2,888 shares

Expires not disclosed

F1 · derivative.exercise_price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F1 · price: The deferred share units were issued pursuant to the Issuer's Compensation Policy for Non-Employee Directors and are convertible into Common Stock on a one-to-one basis.

F3 · derivative.exercise_date: The deferred share units vest upon issuance.

F2 · derivative.exercise_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

F2 · derivative.expiration_date: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

F2 · derivative.underlying: The vested deferred share units are to be settled 100% in shares of Common Stock of the Company upon the reporting person's retirement from the Board of Directors.

Read SEC document
March 07, 2022 Filed Mar 8, 2022 21:05 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 1,047 $56.19 $58,830.93
Disclosure

SEC source: 0001415889-22-002736 · form4-03082022_040325.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP AND CHIEF LEGAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,227

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale occurred automatically to satisfy the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $56.18 to $57.07 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 03, 2022 Filed Mar 8, 2022 21:05 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 1,667 $60.28 $100,486.76
Disclosure

SEC source: 0001415889-22-002736 · form4-03082022_040325.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP AND CHIEF LEGAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,274

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale occurred automatically to satisfy the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person

Read SEC document
March 01, 2022 Filed Mar 4, 2022 01:02 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $61.31 $0.00
Disclosure

SEC source: 0001415889-22-002437 · form4-03032022_050323.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP AND CHIEF LEGAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2032-03-01

F2 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on April 1, 2022 and as to an additional 1/48th of the shares underlying the option each month thereafter.

Read SEC document
March 01, 2022 Filed Mar 4, 2022 01:02 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantCommon Stock 12,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-002437 · form4-03032022_050323.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP AND CHIEF LEGAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,941

F1 · balance_after: The reported transaction involved the Reporting Person's receipt of grant of 12,500 restricted stock units under Issuer's 2015 Stock Option and Incentive Plan.

Read SEC document
December 07, 2021 Filed Dec 9, 2021 21:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $28.36 $0.00
Disclosure

SEC source: 0001179110-21-010721 · edgar.xml · derivative · entry 5

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,000

Underlying: Common Stock · 5,000 shares

Expires 2026-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: This option was granted on October 3, 2016 and fully vested as of the date hereof.

Read SEC document
December 07, 2021 Filed Dec 9, 2021 21:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 100 $95.54 $9,554.00
Disclosure

SEC source: 0001179110-21-010721 · edgar.xml · nonDerivative · entry 4

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,441

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

Read SEC document
December 07, 2021 Filed Dec 9, 2021 21:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 572 $96.38 $55,129.36
Disclosure

SEC source: 0001179110-21-010721 · edgar.xml · nonDerivative · entry 3

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,541

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $95.87 to $96.73 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

Read SEC document
December 07, 2021 Filed Dec 9, 2021 21:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 4,328 $97.46 $421,806.88
Disclosure

SEC source: 0001179110-21-010721 · edgar.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,113

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $96.97 to $97.91 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

Read SEC document
December 07, 2021 Filed Dec 9, 2021 21:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionCommon Stock 5,000 $28.36 $141,800.00
Disclosure

SEC source: 0001179110-21-010721 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,441

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 167 shares that were previously acquired under the Issuer's employee stock purchase plan.

Read SEC document
November 03, 2021 Filed Nov 5, 2021 20:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $28.36 $0.00
Disclosure

SEC source: 0001179110-21-009894 · edgar.xml · derivative · entry 4

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 5,000 shares

Expires 2026-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: This option was granted on October 3, 2016 and fully vested as of the date hereof.

Read SEC document
November 03, 2021 Filed Nov 5, 2021 20:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 800 $109.63 $87,704.00
Disclosure

SEC source: 0001179110-21-009894 · edgar.xml · nonDerivative · entry 3

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,274

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $109.39 to $109.96 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

Read SEC document
November 03, 2021 Filed Nov 5, 2021 20:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 4,200 $110.74 $465,108.00
Disclosure

SEC source: 0001179110-21-009894 · edgar.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,074

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $110.23 to $111.09 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein.

Read SEC document
November 03, 2021 Filed Nov 5, 2021 20:01 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionCommon Stock 5,000 $28.36 $141,800.00
Disclosure

SEC source: 0001179110-21-009894 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,274

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

Read SEC document
September 23, 2021 Filed Sep 27, 2021 20:30 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $28.36 $0.00
Disclosure

SEC source: 0001179110-21-008943 · edgar.xml · derivative · entry 5

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 25,000 shares

Expires 2026-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: This option was granted on October 3, 2016 and fully vested as of the date hereof.

Read SEC document
September 23, 2021 Filed Sep 27, 2021 20:30 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 2,921 $107.75 $314,737.75
Disclosure

SEC source: 0001179110-21-008943 · edgar.xml · nonDerivative · entry 4

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,274

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F5 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $107.74 to $108.08 per share.

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September 23, 2021 Filed Sep 27, 2021 20:30 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 17,317 $108.78 $1,883,743.26
Disclosure

SEC source: 0001179110-21-008943 · edgar.xml · nonDerivative · entry 3

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,195

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $108.18 to $109.08 per share.

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September 23, 2021 Filed Sep 27, 2021 20:30 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 4,762 $109.80 $522,867.60
Disclosure

SEC source: 0001179110-21-008943 · edgar.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,512

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $109.09 to $110.08 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3) through (5) in this form 4.

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September 23, 2021 Filed Sep 27, 2021 20:30 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionCommon Stock 25,000 $28.36 $709,000.00
Disclosure

SEC source: 0001179110-21-008943 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,274

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Effected pursuant to a trading plan adopted on February 22, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 422 shares that were previously acquired under the Issuer's employee stock purchase plan.

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June 29, 2021 Filed Jun 30, 2021 20:22 UTC Kiniksa Pharmaceuticals International, plc KNSA · Entity 1954 GrantShare Option · Derivative 33,237 $0.00 Strike: $14.33 $0.00
Disclosure

SEC source: 0001179110-21-007186 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,237

Underlying: Class A Common Shares · 33,237 shares

Expires 2031-06-28

F1 · derivative.exercise_date: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of grant. The date of grant is June 29, 2021.

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March 04, 2021 Filed Mar 5, 2021 22:50 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 1,772 $86.61 $153,472.92
Disclosure

SEC source: 0001179110-21-003009 · edgar.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,852

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale occurred automatically to satisfy the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

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March 04, 2021 Filed Mar 5, 2021 22:50 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 121 $89.00 $10,769.00
Disclosure

SEC source: 0001179110-21-003009 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,624

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. The sale occurred automatically to satisfy the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $88.99 to $89.00 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 01, 2021 Filed Mar 3, 2021 21:26 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 26,125 $0.00 Strike: $100.13 $0.00
Disclosure

SEC source: 0001179110-21-002666 · edgar.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,125

Underlying: Common Stock · 26,125 shares

Expires 2031-03-01

F2 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on April 1, 2021 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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March 01, 2021 Filed Mar 3, 2021 21:26 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantCommon Stock 13,062 $0.00 $0.00
Disclosure

SEC source: 0001179110-21-002666 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,745

F1 · balance_after: The reported transaction involved the Reporting Person's receipt of a grant of 13,062 restricted stock units under Issuer's 2015 Stock Option and Incentive Plan.

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June 30, 2020 Filed Jul 2, 2020 20:11 UTC Kiniksa Pharmaceuticals International, plc KNSA · Entity 1954 GrantShare Option · Derivative 18,760 $0.00 Strike: $25.48 $0.00
Disclosure

SEC source: 0001104659-20-080547 · a4.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,760

Underlying: Class A Common Shares · 18,760 shares

Expires 2030-06-29

F1 · derivative.exercise_date: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of grant. The date of grant is June 30, 2020.

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March 09, 2020 Filed Mar 11, 2020 20:28 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 617 $51.98 $32,071.66
Disclosure

SEC source: 0001179110-20-003470 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,683

F1 · kind: The sale reported on this Form 4 represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units.The sale occurred automatically to satisfy the tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

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March 01, 2020 Filed Mar 4, 2020 00:10 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 28,500 $0.00 Strike: $54.13 $0.00
Disclosure

SEC source: 0001179110-20-002961 · edgar.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,500

Underlying: Common Stock · 28,500 shares

Expires 2030-03-01

F2 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on April 1, 2020 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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March 01, 2020 Filed Mar 4, 2020 00:10 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantCommon Stock 14,250 $0.00 $0.00
Disclosure

SEC source: 0001179110-20-002961 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,300

F1 · balance_after: The reported transaction involved the Reporting Person's receipt of a grant of 14,250 restricted stock units under Issuer's 2015 Stock Option and Incentive Plan. The Reporting Person has reported prior awards of restricted stock units in Table II of Form 4. The total reported in Column 5 includes the 14,250 newly awarded restricted stock units, and 8,050 previously reported restricted stock units, 2,013 of which vested on March 1, 2020.

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May 29, 2019 Filed May 30, 2019 22:32 UTC Kiniksa Pharmaceuticals International, plc KNSA · Entity 1954 GrantShare Option · Derivative 18,760 $0.00 Strike: $15.47 $0.00
Disclosure

SEC source: 0001179110-19-006867 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,760

Underlying: Class A Common Shares · 18,760 shares

Expires 2029-05-28

F1 · derivative.exercise_date: The option vests and becomes exercisable in twelve substantially equal monthly installments following the date of grant. The date of grant is May 29, 2019.

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March 01, 2019 Filed Mar 5, 2019 22:25 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantRestricted Stock Units · Derivative 8,050 $0.00 $0.00
Disclosure

SEC source: 0001179110-19-003308 · edgar.xml · derivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,050

Underlying: Common Stock · 8,050 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments on March 1, 2020, 2021, 2022 and 2023.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments on March 1, 2020, 2021, 2022 and 2023.

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March 01, 2019 Filed Mar 5, 2019 22:25 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 29,900 $0.00 Strike: $86.60 $0.00
Disclosure

SEC source: 0001179110-19-003308 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,900

Underlying: Common Stock · 29,900 shares

Expires 2029-03-01

F1 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on April 1, 2019 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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February 27, 2018 Filed Mar 1, 2018 22:08 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionStock Option (Right to Buy) · Derivative 10,000 $0.00 Strike: $28.36 $0.00
Disclosure

SEC source: 0001179110-18-003163 · edgar.xml · derivative · entry 5

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,000

Underlying: Common Stock · 10,000 shares

Expires 2026-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise reported on this Form 4 was effected pursuant to a trading plan adopted on December 18, 2017 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended (the "Exchange Act").

F5 · derivative.exercise_date: This option was granted on October 3, 2016. This option vested with respect to 25% of the shares underlying the option on September 6, 2017 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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February 27, 2018 Filed Mar 1, 2018 22:08 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 1,106 $87.69 $96,985.14
Disclosure

SEC source: 0001179110-18-003163 · edgar.xml · nonDerivative · entry 4

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported on this Form 4 were effected pursuant to a trading plan adopted on December 18, 2017 pursuant to Rule 10b5-1 under the Exchange Act.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $87.47 to $87.85 per share.

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February 27, 2018 Filed Mar 1, 2018 22:08 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 8,794 $88.40 $777,389.60
Disclosure

SEC source: 0001179110-18-003163 · edgar.xml · nonDerivative · entry 3

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,106

F2 · kind: The sales reported on this Form 4 were effected pursuant to a trading plan adopted on December 18, 2017 pursuant to Rule 10b5-1 under the Exchange Act.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $87.90 to $88.88 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3) and (4) to this Form 4.

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February 27, 2018 Filed Mar 1, 2018 22:08 UTC Blueprint Medicines Corp BPMC · Entity 77326 SaleCommon Stock 100 $90.75 $9,075.00
Disclosure

SEC source: 0001179110-18-003163 · edgar.xml · nonDerivative · entry 2

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,900

F2 · kind: The sales reported on this Form 4 were effected pursuant to a trading plan adopted on December 18, 2017 pursuant to Rule 10b5-1 under the Exchange Act.

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February 27, 2018 Filed Mar 1, 2018 22:08 UTC Blueprint Medicines Corp BPMC · Entity 77326 Exercise / conversionCommon Stock 10,000 $28.36 $283,600.00
Disclosure

SEC source: 0001179110-18-003163 · edgar.xml · nonDerivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise reported on this Form 4 was effected pursuant to a trading plan adopted on December 18, 2017 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended (the "Exchange Act").

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February 16, 2018 Filed Feb 20, 2018 22:33 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 39,000 $0.00 Strike: $81.44 $0.00
Disclosure

SEC source: 0001179110-18-002415 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,000

Underlying: Common Stock · 39,000 shares

Expires 2028-02-16

F1 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on March 16, 2018 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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February 16, 2017 Filed Feb 21, 2017 21:42 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $36.05 $0.00
Disclosure

SEC source: 0001179110-17-002770 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 5,000 shares

Expires 2027-02-16

F1 · derivative.exercise_date: This option vests with respect to 1/48th of the shares underlying the option on March 16, 2017 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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October 03, 2016 Filed Oct 4, 2016 22:22 UTC Blueprint Medicines Corp BPMC · Entity 77326 GrantStock Option (Right to Buy) · Derivative 100,000 $0.00 Strike: $28.36 $0.00
Disclosure

SEC source: 0001179110-16-030355 · edgar.xml · derivative · entry 1

McCain Tracey L · CIK 0001683600 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2026-10-03

F1 · date: In accordance with the Issuer's equity award grant policy, this option was granted effective as of the first day of the month following the commencement of the Reporting Person's employment with the Issuer on September 6, 2016.

F2 · derivative.exercise_date: This option vests with respect to 25% of the shares underlying the option on September 6, 2017 and as to an additional 1/48th of the shares underlying the option each month thereafter.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.