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person · Reporting owner

Detheux Michel

Disclosed activity across 2 companies

Tapewire entity
38789
SEC CIK
0001816196

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Vor Biopharma Inc.VOR · Entity 4763DirectorJune 11, 2026June 13, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Vor Biopharma Inc.

Report date June 11, 2026 · Filed June 13, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $14.09 · Expires 2036-06-10Direct57,162 Reported balance After 2026-06-11 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-11 · Grant · Acquired 57,162 · Balance 57,162

F1: One thirty-sixth of the shares subject to the option shall vest and become exercisable on July 11, 2026 and each month thereafter, subject to the Reporting Person's continued service through each such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: One thirty-sixth of the shares subject to the option shall vest and become exercisable on July 11, 2026 and each month thereafter, subject to the Reporting Person's continued service through each such vesting date.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

iTeos Therapeutics, Inc.

Report date August 29, 2025 · Filed August 29, 2025

Section 16 reporting ended · disclosed 2025-08-29. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2025-08-29 transaction · row 1
1 source row

Row 1 · 2025-08-29 · Other · Disposed 153,903 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F2: The amount reported in Column 4 includes 108,875 restricted stock units of the Company ("Company Restricted Stock Units," and each such restricted stock unit, a "Company Restricted Stock Unit"). Pursuant to the actions of the of the Compensation and Leadership Development Committee of the Board of Directors of the Company (the "Committee") and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, (A) each Company Restricted Stock Unit that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or

F3: (Continued from footnote 2) within a specified time following, a sale of the Company (each such Company Restricted Stock Unit, an "Accelerated Vesting Restricted Stock Unit") that was then outstanding but not then vested became immediately vested in full and (B) each Accelerated Vesting Restricted Stock Unit that was then outstanding was canceled and, in exchange therefor, the holder of such canceled Company Restricted Stock Unit became entitled to receive in consideration of the cancellation of such Company Restricted Stock Unit (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the Cash Amount and (y) one CVR.

Common StockSEC Table I · non-derivativeIndirectBy MG3A0 Reported balance After 2025-08-29 transaction · row 2 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 2 · 2025-08-29 · Other · Disposed 94,027 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F4: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $7.05Direct0 Reported balance After 2025-08-29 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2025-08-29 · Disposition to issuer · Disposed 14,185 · Balance 0

F5: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $7.05Direct0 Reported balance After 2025-08-29 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2025-08-29 · Disposition to issuer · Disposed 444,815 · Balance 0

F5: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.24Direct0 Reported balance After 2025-08-29 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2025-08-29 · Disposition to issuer · Disposed 94,336 · Balance 0

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.24Direct0 Reported balance After 2025-08-29 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2025-08-29 · Disposition to issuer · Disposed 50,128 · Balance 0

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.16Direct0 Reported balance After 2025-08-29 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2025-08-29 · Disposition to issuer · Disposed 17,544 · Balance 0

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.24IndirectBy MG3A0 Reported balance After 2025-08-29 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2025-08-29 · Disposition to issuer · Disposed 185,000 · Balance 0

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F4: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.16IndirectBy MG3A0 Reported balance After 2025-08-29 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2025-08-29 · Disposition to issuer · Disposed 52,700 · Balance 0

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F4: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F2: The amount reported in Column 4 includes 108,875 restricted stock units of the Company ("Company Restricted Stock Units," and each such restricted stock unit, a "Company Restricted Stock Unit"). Pursuant to the actions of the of the Compensation and Leadership Development Committee of the Board of Directors of the Company (the "Committee") and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, (A) each Company Restricted Stock Unit that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or

F3: (Continued from footnote 2) within a specified time following, a sale of the Company (each such Company Restricted Stock Unit, an "Accelerated Vesting Restricted Stock Unit") that was then outstanding but not then vested became immediately vested in full and (B) each Accelerated Vesting Restricted Stock Unit that was then outstanding was canceled and, in exchange therefor, the holder of such canceled Company Restricted Stock Unit became entitled to receive in consideration of the cancellation of such Company Restricted Stock Unit (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the Cash Amount and (y) one CVR.

F4: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

F5: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
June 11, 2026 Filed Jun 13, 2026 00:42 UTC Vor Biopharma Inc. VOR · Entity 4763 GrantStock option (right to buy) · Derivative 57,162 $0.00 Strike: $14.09 $0.00
Disclosure

SEC source: 0001193125-26-270002 · ownership.xml · derivative · entry 1

Detheux Michel · CIK 0001816196 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,162

Underlying: Common stock · 57,162 shares

Expires 2036-06-10

F1 · derivative.exercise_date: One thirty-sixth of the shares subject to the option shall vest and become exercisable on July 11, 2026 and each month thereafter, subject to the Reporting Person's continued service through each such vesting date.

Read SEC document
August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 52,700 Not disclosed Strike: $6.16 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 9

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MG3A

Disclosed balance after: 0

Underlying: Common Stock · 52,700 shares

Expires not disclosed

F6 · kind: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F4 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 185,000 Not disclosed Strike: $4.24 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 8

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MG3A

Disclosed balance after: 0

Underlying: Common Stock · 185,000 shares

Expires not disclosed

F6 · kind: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F4 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 17,544 Not disclosed Strike: $6.16 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 7

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,544 shares

Expires not disclosed

F6 · kind: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 50,128 Not disclosed Strike: $4.24 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 6

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 50,128 shares

Expires not disclosed

F6 · kind: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 94,336 Not disclosed Strike: $4.24 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 5

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 94,336 shares

Expires not disclosed

F6 · kind: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 444,815 Not disclosed Strike: $7.05 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 4

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 444,815 shares

Expires not disclosed

F5 · kind: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F5 · price: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F5 · derivative.exercise_date: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F5 · derivative.expiration_date: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Disposition to issuerStock Option (Right to Buy) · Derivative 14,185 Not disclosed Strike: $7.05 Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · derivative · entry 3

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 14,185 shares

Expires not disclosed

F5 · kind: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F5 · price: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · price: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F5 · derivative.exercise_date: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · derivative.exercise_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

F5 · derivative.expiration_date: Pursuant to the actions of the of the Committee and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each option to purchase Shares from the Company ("Company Stock Options," and each such option, a "Company Stock Option") that was then outstanding but not then vested or exercisable and that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or within a specified time following, a sale of the Company became immediately vested and exercisable in full.

F6 · derivative.expiration_date: In accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, each Company Stock Option that had an exercise price per share that is less than the Cash Amount (each, an "In-the-Money Option") that was then outstanding was canceled and, in exchange therefor, the holder of such canceled In-the-Money Option became entitled to receive in consideration of the cancellation of such In-the-Money Option (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the product obtained by multiplying (1) the excess of the Cash Amount over the exercise price per Share underlying such In-the-Money Option by (2) the number of Shares underlying such In-the-Money Option as of immediately prior to the Effective Time and (y) one CVR for each Share underlying such In-the-Money Option.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 OtherCommon Stock 94,027 Not disclosed Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · nonDerivative · entry 2

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F1 · price: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F4 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

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August 29, 2025 Filed Aug 29, 2025 16:30 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 OtherCommon Stock 153,903 Not disclosed Not disclosed
Disclosure

SEC source: 0000950170-25-112240 · ownership.xml · nonDerivative · entry 1

Detheux Michel · CIK 0001816196 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · kind: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F2 · kind: The amount reported in Column 4 includes 108,875 restricted stock units of the Company ("Company Restricted Stock Units," and each such restricted stock unit, a "Company Restricted Stock Unit"). Pursuant to the actions of the of the Compensation and Leadership Development Committee of the Board of Directors of the Company (the "Committee") and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, (A) each Company Restricted Stock Unit that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or

F3 · kind: (Continued from footnote 2) within a specified time following, a sale of the Company (each such Company Restricted Stock Unit, an "Accelerated Vesting Restricted Stock Unit") that was then outstanding but not then vested became immediately vested in full and (B) each Accelerated Vesting Restricted Stock Unit that was then outstanding was canceled and, in exchange therefor, the holder of such canceled Company Restricted Stock Unit became entitled to receive in consideration of the cancellation of such Company Restricted Stock Unit (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the Cash Amount and (y) one CVR.

F1 · price: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated as of July 18, 2025, by and among iTeos Therapeutics, Inc. (the "Company"), Concentra Biosciences LLC ("Parent"), and Concentra Merger Sub VIII, Inc., a wholly-owned subsidiary of Parent ("Merger Sub"), pursuant to which Parent completed a tender offer for shares of common stock of the Company ("Shares") and thereafter, the Merger Sub merged with and into the Company (the "Merger"). At the effective time of the Merger (the "Effective Time"), each issued and outstanding Share was canceled and converted into the right to receive (i) $10.047 in cash per share (the "Cash Amount"); plus (ii) one non-transferable contractual contingent value right per share (each, a "CVR"), without interest and subject to applicable withholding of taxes.

F2 · price: The amount reported in Column 4 includes 108,875 restricted stock units of the Company ("Company Restricted Stock Units," and each such restricted stock unit, a "Company Restricted Stock Unit"). Pursuant to the actions of the of the Compensation and Leadership Development Committee of the Board of Directors of the Company (the "Committee") and in accordance with the terms of the Merger Agreement, at the Effective Time, by virtue of the Merger and without any action on the part of the holders, (A) each Company Restricted Stock Unit that was held by a Company service provider who was subject to an individual employment or other agreement and/or a Company severance and change in control plan or agreement that provides for accelerated vesting of time-based equity awards upon the occurrence of a sale of the Company or a qualifying termination of employment or service in connection with, or

F3 · price: (Continued from footnote 2) within a specified time following, a sale of the Company (each such Company Restricted Stock Unit, an "Accelerated Vesting Restricted Stock Unit") that was then outstanding but not then vested became immediately vested in full and (B) each Accelerated Vesting Restricted Stock Unit that was then outstanding was canceled and, in exchange therefor, the holder of such canceled Company Restricted Stock Unit became entitled to receive in consideration of the cancellation of such Company Restricted Stock Unit (x) an amount in cash without interest, subject to any applicable tax withholding, equal to the Cash Amount and (y) one CVR.

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July 16, 2025 Filed Jul 18, 2025 21:16 UTC Vor Biopharma Inc. VOR · Entity 4763 GrantStock Option (right to buy) · Derivative 60,000 $0.00 Strike: $2.12 $0.00
Disclosure

SEC source: 0001415889-25-020024 · form4-07182025_090713.xml · derivative · entry 1

Detheux Michel · CIK 0001816196 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2035-07-15

F1 · derivative.exercise_date: One thirty-sixth of the shares subject to the option shall vest and become exercisable on August 16, 2025 and each month thereafter, subject to the Reporting Person's continued service through each such vesting date.

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June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 94,027 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 16

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 3

Underlying: Common Stock · 94,027 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · kind: This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

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June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 18,000 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 15

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 18,000 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · kind: This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 43,883 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 14

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 94,030

Underlying: Common Stock · 43,883 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

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June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 8,400 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 13

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 8,400 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 94,027 $4.30 $404,316.10
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 10

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 94,027

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · kind: This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 18,000 $4.30 $77,400.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 9

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,903

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · kind: This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 43,883 $10.02 $439,707.66
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 8

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.99 to $10.06, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 43,883 $4.30 $188,696.90
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 7

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 43,883

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 8,400 $10.02 $84,168.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 6

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,903

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.99 to $10.06, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
June 10, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 8,400 $4.30 $36,120.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 5

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 43,882 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 12

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 137,913

Underlying: Common Stock · 43,882 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 8,400 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · derivative · entry 11

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,400

Underlying: Common Stock · 8,400 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 43,882 $10.03 $440,136.46
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 4

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.98 to $10.17, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 43,882 $4.30 $188,692.60
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 3

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 43,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 8,400 $10.03 $84,252.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 2

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,903

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.01 to $10.17, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
June 09, 2025 Filed Jun 11, 2025 21:01 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 8,400 $4.30 $36,120.00
Disclosure

SEC source: 0000950170-25-085047 · ownership.xml · nonDerivative · entry 1

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 43,882 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 18

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 181,795

Underlying: Common Stock · 43,882 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 8,400 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 17

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,800

Underlying: Common Stock · 8,400 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 43,882 $10.21 $448,035.22
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 12

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.15 to $10.31, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 43,882 $4.30 $188,692.60
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 11

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 43,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 8,400 $10.21 $85,764.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 10

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,903

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.15 to $10.31, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
June 06, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 8,400 $4.30 $36,120.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 9

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 43,882 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 16

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 225,677

Underlying: Common Stock · 43,882 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 8,400 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 15

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 43,200

Underlying: Common Stock · 8,400 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 43,882 $10.15 $445,402.30
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 8

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.08 to $10.22, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 43,882 $4.30 $188,692.60
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 7

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 43,882

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 8,400 $10.15 $85,260.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 6

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,903

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.08 to $10.22, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
June 05, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 8,400 $4.30 $36,120.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 5

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 43,883 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 14

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 269,559

Underlying: Common Stock · 43,883 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionStock Option (Right to Buy) · Derivative 8,400 $0.00 Strike: $4.30 $0.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · derivative · entry 13

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,600

Underlying: Common Stock · 8,400 shares

Expires 2025-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 43,883 $10.10 $443,218.30
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 4

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 0

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.01 to $10.21, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 43,883 $4.30 $188,696.90
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 3

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · By MG3A

Disclosed balance after: 43,883

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F3 · ownership.nature: MG3A is a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 SaleCommon Stock 8,400 $10.10 $84,840.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 2

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,903

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.20, inclusive. The reporting person undertakes to provide to iTeos Therapeutics, Inc., any security holder of iTeos Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 21:03 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 Exercise / conversionCommon Stock 8,400 $4.30 $36,120.00
Disclosure

SEC source: 0000950170-25-083411 · ownership.xml · nonDerivative · entry 1

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 5, 2025.

Read SEC document
March 07, 2025 Filed Mar 11, 2025 20:00 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 GrantStock Option (Right to Buy) · Derivative 459,000 $0.00 Strike: $7.05 $0.00
Disclosure

SEC source: 0000950170-25-037515 · ownership.xml · derivative · entry 2

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 459,000

Underlying: Common Stock · 459,000 shares

Expires 2035-03-07

F2 · derivative.exercise_date: This stock option shall vest over four years, with 25% vesting on March 7, 2026 and thereafter in equal monthly installments over the next 36 months, subject to the reporting person's continued service to the issuer.

Read SEC document
March 07, 2025 Filed Mar 11, 2025 20:00 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 GrantCommon Stock 77,000 $0.00 $0.00
Disclosure

SEC source: 0000950170-25-037515 · ownership.xml · nonDerivative · entry 1

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 135,903

F1 · price: The reporting person was granted restricted stock units ("RSUs"). Each RSU represents the right to receive one share of common stock. The shares of common stock underlying the RSUs will vest over 4 years: 25% will vest on March 7, 2026 and the remainder will vest equally, on an annual basis, over the remaining 3 years, subject to the reporting person's continued service to the issuer.

Read SEC document
August 08, 2024 Filed Aug 9, 2024 20:00 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 GiftStock Option (Right to Buy) · Derivative 442,800 $0.00 Strike: $11.58 $0.00
Disclosure

SEC source: 0000950170-24-094990 · ownership.xml · derivative · entry 2

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MG3A

Disclosed balance after: 442,800

Underlying: Common Stock · 442,800 shares

Expires 2034-03-07

F1 · kind: The reporting person transferred this stock option to MG3A, a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

F2 · derivative.exercise_date: This stock option vests over four years, with 25% vesting on March 7, 2025 and thereafter in equal monthly installments over the next 36 months, subject to the reporting person's continued service to the Issuer.

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August 08, 2024 Filed Aug 9, 2024 20:00 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 GiftStock Option (Right to Buy) · Derivative 442,800 $0.00 Strike: $11.58 $0.00
Disclosure

SEC source: 0000950170-24-094990 · ownership.xml · derivative · entry 1

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 147,600

Underlying: Common Stock · 442,800 shares

Expires 2034-03-07

F1 · kind: The reporting person transferred this stock option to MG3A, a Belgian partnership of which the reporting person is the manager and the reporting person's spouse is the successor manager.

F2 · derivative.exercise_date: This stock option vests over four years, with 25% vesting on March 7, 2025 and thereafter in equal monthly installments over the next 36 months, subject to the reporting person's continued service to the Issuer.

Read SEC document
March 07, 2024 Filed Mar 8, 2024 19:57 UTC iTeos Therapeutics, Inc. ITOS · Entity 75965 GrantStock Option (Right to Buy) · Derivative 590,400 $0.00 Strike: $11.58 $0.00
Disclosure

SEC source: 0000950170-24-028855 · ownership.xml · derivative · entry 1

Detheux Michel · CIK 0001816196 · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 590,400

Underlying: Common Stock · 590,400 shares

Expires 2034-03-07

F1 · derivative.exercise_date: This stock option shall vest over four years, with 25% vesting on March 7, 2025 and thereafter in equal monthly installments over the next 36 months, subject to the reporting person's continued service to the Issuer.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.