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person · Reporting owner

Shacham Sharon

Disclosed activity across 3 companies

Tapewire entity
36224
SEC CIK
0001588438

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Acrivon Therapeutics, Inc.ACRV · Entity 573DirectorJune 17, 2026June 22, 2026
Karyopharm Therapeutics Inc.KPTI · Entity 781Chief Scientific OfficerMarch 29, 2022March 31, 2022
Nasus Pharma LtdNSRX · Entity 7254DirectorMarch 18, 2026March 28, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Acrivon Therapeutics, Inc.

Report date June 17, 2026 · Filed June 22, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $1.52 · Expires 2036-06-16Direct20,275 Reported balance After 2026-06-17 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-17 · Grant · Acquired 20,275 · Balance 20,275

F1: The shares subject to the option shall vest on the date immediately preceding the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continuous service through the applicable vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares subject to the option shall vest on the date immediately preceding the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continuous service through the applicable vesting date.

Karyopharm Therapeutics Inc.

Report date March 29, 2022 · Filed March 31, 2022

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect958,131 Reported balance After 2022-03-29 transaction · row 1
1 source row

Row 1 · 2022-03-29 · Grant · Acquired 60,000 · Balance 958,131

F1: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 28, 2023.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $10.33 · Expires 2032-03-28Direct90,000 Reported balance After 2022-03-29 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2022-03-29 · Grant · Acquired 90,000 · Balance 90,000

F2: This option was granted on March 29, 2022 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 28, 2023, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Common StockSEC Table I · non-derivativeIndirectBy Spouse713,757 Reported balance Holding disclosure · report date 2022-03-29 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 713,757

Filing footnotes · ownership attribution and instrument terms

F1: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 28, 2023.

F2: This option was granted on March 29, 2022 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 28, 2023, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Nasus Pharma Ltd

Report date March 18, 2026 · Filed March 28, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Share Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.38 · Expires 2035-12-11DirectNot disclosed Reported balance Holding disclosure · report date 2026-03-18 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: Options to purchase 10,000 ordinary shares of the Issuer, no par value ("Ordinary Shares") were granted on December 11, 2025, with 2.0833% of the total grant vesting monthly following December 11, 2025. As of March 18, 2026, 10,000 options remain outstanding, of which 625 are vested and exercisable, at an exercise price of $5.38 per share, expiring December 11, 2035.

Filing footnotes · ownership attribution and instrument terms

F1: Options to purchase 10,000 ordinary shares of the Issuer, no par value ("Ordinary Shares") were granted on December 11, 2025, with 2.0833% of the total grant vesting monthly following December 11, 2025. As of March 18, 2026, 10,000 options remain outstanding, of which 625 are vested and exercisable, at an exercise price of $5.38 per share, expiring December 11, 2035.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 07, 2018 Filed May 8, 2018 20:19 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-028569 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,697

Underlying: Common Stock · 10,000 shares

Expires 2021-12-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 14, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
May 07, 2018 Filed May 8, 2018 20:19 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $16.77 $167,747.00
Disclosure

SEC source: 0001209191-18-028569 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $16.45 to $17.02, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
May 07, 2018 Filed May 8, 2018 20:19 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-028569 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
April 18, 2018 Filed Apr 20, 2018 20:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 7,576 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-025694 · doc4.xml · derivative · entry 7

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 18,181

Underlying: Common Stock · 7,576 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F6 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on June 18, 2013, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
April 18, 2018 Filed Apr 20, 2018 20:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 2,424 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-025694 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 0

Underlying: Common Stock · 2,424 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
April 18, 2018 Filed Apr 20, 2018 20:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $14.79 $147,878.00
Disclosure

SEC source: 0001209191-18-025694 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 512,143

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.665 to $15.09, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
April 18, 2018 Filed Apr 20, 2018 20:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-025694 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 522,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
April 09, 2018 Filed Apr 10, 2018 20:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-024504 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,697

Underlying: Common Stock · 10,000 shares

Expires 2021-12-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 14, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
April 09, 2018 Filed Apr 10, 2018 20:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $12.48 $124,829.00
Disclosure

SEC source: 0001209191-18-024504 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $12.20 to $12.64, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
April 09, 2018 Filed Apr 10, 2018 20:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-024504 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
March 19, 2018 Filed Mar 20, 2018 20:36 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-020884 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 2,424

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
March 19, 2018 Filed Mar 20, 2018 20:36 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $15.29 $152,895.00
Disclosure

SEC source: 0001209191-18-020884 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 512,143

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.90 to $15.89, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
March 19, 2018 Filed Mar 20, 2018 20:36 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-020884 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 522,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
March 07, 2018 Filed Mar 8, 2018 22:54 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 606 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-018197 · doc4.xml · derivative · entry 7

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,697

Underlying: Common Stock · 606 shares

Expires 2021-12-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F6 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 14, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
March 07, 2018 Filed Mar 8, 2018 22:54 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 9,394 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-018197 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 9,394 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
March 07, 2018 Filed Mar 8, 2018 22:54 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $16.15 $161,463.00
Disclosure

SEC source: 0001209191-18-018197 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $15.89 to $16.41, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
March 07, 2018 Filed Mar 8, 2018 22:54 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-018197 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
February 20, 2018 Filed Feb 22, 2018 21:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-012382 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 12,424

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
February 20, 2018 Filed Feb 22, 2018 21:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $14.79 $147,872.00
Disclosure

SEC source: 0001209191-18-012382 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 512,143

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $14.51 to $15.015, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
February 20, 2018 Filed Feb 22, 2018 21:17 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-012382 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 522,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
February 07, 2018 Filed Feb 8, 2018 21:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-008415 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,394

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
February 07, 2018 Filed Feb 8, 2018 21:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $12.50 $125,048.00
Disclosure

SEC source: 0001209191-18-008415 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $12.40 to $12.67, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
February 07, 2018 Filed Feb 8, 2018 21:07 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-008415 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
January 24, 2018 Filed Jan 25, 2018 21:28 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantStock Option (right to buy) · Derivative 200,000 $0.00 Strike: $10.45 $0.00
Disclosure

SEC source: 0001209191-18-005379 · doc4.xml · derivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 200,000

Underlying: Common Stock · 200,000 shares

Expires 2028-01-23

F1 · derivative.exercise_date: This option was granted on January 24, 2018. The shares underlying this option vest as to 25% of the shares on January 24, 2019, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 24, 2018 Filed Jan 25, 2018 21:28 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantStock Option (right to buy) · Derivative 200,000 $0.00 Strike: $10.45 $0.00
Disclosure

SEC source: 0001209191-18-005379 · doc4.xml · derivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Common Stock · 200,000 shares

Expires 2028-01-23

F1 · derivative.exercise_date: This option was granted on January 24, 2018. The shares underlying this option vest as to 25% of the shares on January 24, 2019, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
January 18, 2018 Filed Jan 22, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-004725 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 22,424

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

Read SEC document
January 18, 2018 Filed Jan 22, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $10.09 $100,882.00
Disclosure

SEC source: 0001209191-18-004725 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 512,143

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $9.90 to $10.15, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
January 18, 2018 Filed Jan 22, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-004725 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 522,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

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January 08, 2018 Filed Jan 9, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-18-002907 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,394

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

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January 08, 2018 Filed Jan 9, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $10.08 $100,769.00
Disclosure

SEC source: 0001209191-18-002907 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $9.96 to $10.29, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

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January 08, 2018 Filed Jan 9, 2018 21:08 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-18-002907 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

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December 18, 2017 Filed Dec 20, 2017 21:21 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-17-066639 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 32,424

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F5 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

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December 18, 2017 Filed Dec 20, 2017 21:21 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $9.16 $91,553.00
Disclosure

SEC source: 0001209191-17-066639 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 512,143

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $9.0501 to $9.3500, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

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December 18, 2017 Filed Dec 20, 2017 21:21 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-17-066639 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 522,143

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:05 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $0.26 $0.00
Disclosure

SEC source: 0001209191-17-064683 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,394

Underlying: Common Stock · 10,000 shares

Expires 2021-12-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F7 · derivative.exercise_date: This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on December 12, 2012, and the remaining 75% vested in 36 equal monthly installments thereafter.

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December 07, 2017 Filed Dec 8, 2017 21:05 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 SaleCommon Stock 10,000 $10.39 $103,903.00
Disclosure

SEC source: 0001209191-17-064683 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 713,510

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $10.14 to $10.48, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
December 07, 2017 Filed Dec 8, 2017 21:05 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 Exercise / conversionCommon Stock 10,000 $0.26 $2,640.00
Disclosure

SEC source: 0001209191-17-064683 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 723,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: Reflects the contribution of 60,000 shares previously owned directly to the Sharon Shacham 2016 Qualified Annuity Interest Trust ("GRAT") on September 9, 2016 and the transfer of 12,691 shares from the GRAT to the reporting person on November 6, 2017.

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January 20, 2017 Filed Jan 24, 2017 22:34 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantStock Option (right to buy) · Derivative 250,000 $0.00 Strike: $10.39 $0.00
Disclosure

SEC source: 0001209191-17-005323 · doc4.xml · derivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 250,000

Underlying: Common Stock · 250,000 shares

Expires 2027-01-19

F1 · derivative.exercise_date: This option was granted on January 20, 2017. The shares underlying this option vest as to 25% of the shares on January 20, 2018, with the remaining 75% vesting in 36 equal monthly installments thereafter.

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January 20, 2017 Filed Jan 24, 2017 22:34 UTC Karyopharm Therapeutics Inc. KPTI · Entity 781 GrantStock Option (right to buy) · Derivative 250,000 $0.00 Strike: $10.39 $0.00
Disclosure

SEC source: 0001209191-17-005323 · doc4.xml · derivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Stock · 250,000 shares

Expires 2027-01-19

F1 · derivative.exercise_date: This option was granted on January 20, 2017. The shares underlying this option vest as to 25% of the shares on January 20, 2018, with the remaining 75% vesting in 36 equal monthly installments thereafter.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.