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Smith Michael Alexander

Disclosed activity across 1 company

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35782
SEC CIK
0001870278

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
INSMED IncINSM · Entity 3174Chief Legal OfficerJune 22, 2026June 24, 2026

Disclosed balances

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Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

INSMED Inc

Report date June 22, 2026 · Filed June 24, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect37,648 Reported balance After 2026-06-22 transaction · row 1
1 source row

Row 1 · 2026-06-22 · Sale · Disposed 1,806 · Balance 37,648

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
June 22, 2026 Filed Jun 24, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,806 $95.82 $173,050.92
Disclosure

SEC source: 0001870278-26-000020 · wk-form4_1782331897.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,648

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:14 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,159 $102.27 $220,800.93
Disclosure

SEC source: 0001870278-26-000017 · wk-form4_1780690451.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,454

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
May 22, 2026 Filed May 22, 2026 20:25 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,149 $108.47 $666,982.03
Disclosure

SEC source: 0001870278-26-000015 · wk-form4_1779481519.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,613

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 13, 2026 Filed May 15, 2026 20:07 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,109 $116.18 $477,383.62
Disclosure

SEC source: 0001870278-26-000012 · wk-form4_1778875647.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,762

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
March 30, 2026 Filed Mar 31, 2026 20:13 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 13,989 $0.00 Strike: $27.89 $0.00
Disclosure

SEC source: 0001870278-26-000010 · wk-form4_1774988003.xml · derivative · entry 5

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,561

Underlying: Common Stock · 13,989 shares

Expires 2031-07-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 30, 2026 Filed Mar 31, 2026 20:13 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 5,649 $0.00 Strike: $17.07 $0.00
Disclosure

SEC source: 0001870278-26-000010 · wk-form4_1774988003.xml · derivative · entry 4

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,633

Underlying: Common Stock · 5,649 shares

Expires 2032-05-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 30, 2026 Filed Mar 31, 2026 20:13 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 19,638 $150.98 $2,964,945.24
Disclosure

SEC source: 0001870278-26-000010 · wk-form4_1774988003.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,871

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 30, 2026 Filed Mar 31, 2026 20:13 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 13,989 $27.89 $390,153.21
Disclosure

SEC source: 0001870278-26-000010 · wk-form4_1774988003.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,509

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 30, 2026 Filed Mar 31, 2026 20:13 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 5,649 $17.07 $96,428.43
Disclosure

SEC source: 0001870278-26-000010 · wk-form4_1774988003.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,520

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 24, 2026 Filed Feb 25, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 20,248 $0.00 Strike: $17.07 $0.00
Disclosure

SEC source: 0001870278-26-000008 · wk-form4_1772053483.xml · derivative · entry 5

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,282

Underlying: Common Stock · 20,248 shares

Expires 2032-05-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
February 24, 2026 Filed Feb 25, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 15,771 $156.53 $2,468,634.63
Disclosure

SEC source: 0001870278-26-000008 · wk-form4_1772053483.xml · nonDerivative · entry 4

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,871

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 15,771 shares sold at prices ranging from $156.00 to $156.86 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 24, 2026 Filed Feb 25, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,151 $155.06 $643,654.06
Disclosure

SEC source: 0001870278-26-000008 · wk-form4_1772053483.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,642

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 4,151 shares sold at prices ranging from $154.47 to $155.45 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 24, 2026 Filed Feb 25, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,852 $153.93 $746,868.36
Disclosure

SEC source: 0001870278-26-000008 · wk-form4_1772053483.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,793

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 4,852 shares sold at prices ranging from $153.47 to $154.46 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 24, 2026 Filed Feb 25, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 20,248 $17.07 $345,633.36
Disclosure

SEC source: 0001870278-26-000008 · wk-form4_1772053483.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 76,645

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 03, 2026 Filed Feb 4, 2026 21:15 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 640 $156.27 $100,012.80
Disclosure

SEC source: 0001870278-26-000006 · wk-form4_1770239741.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,397

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 08, 2026 Filed Jan 8, 2026 22:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,053 $174.17 $183,401.01
Disclosure

SEC source: 0001870278-26-000004 · wk-form4_1767910777.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,037

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 07, 2026 Filed Jan 8, 2026 22:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 709 $175.07 $124,124.63
Disclosure

SEC source: 0001870278-26-000004 · wk-form4_1767910777.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,090

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 06, 2026 Filed Jan 8, 2026 22:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,396 $173.33 $241,968.68
Disclosure

SEC source: 0001870278-26-000004 · wk-form4_1767910777.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,799

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:05 UTC INSMED Inc INSM · Entity 3174 GrantStock Option (right to buy) · Derivative 27,600 $0.00 Strike: $177.12 $0.00
Disclosure

SEC source: 0001870278-26-000002 · wk-form4_1767733498.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,600

Underlying: Common Stock · 27,600 shares

Expires 2036-01-02

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:05 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 5,293 Not disclosed Not disclosed
Disclosure

SEC source: 0001870278-26-000002 · wk-form4_1767733498.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,195

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on January 2, 2026 for no consideration.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 27,130 $0.00 Strike: $23.75 $0.00
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · derivative · entry 10

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 27,130 shares

Expires 2030-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F10 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,400 $187.97 $263,158.00
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 9

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,902

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · price: This is the weighted average sales price representing 1,400 shares sold at prices ranging from $187.88 to $188.13 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,572 $187.15 $294,199.80
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 8

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,302

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · price: This is the weighted average sales price representing 1,572 shares sold at prices ranging from $186.61 to $187.53 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,636 $185.93 $676,041.48
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 7

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,874

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 3,636 shares sold at prices ranging from $185.51 to $186.45 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,243 $184.91 $599,663.13
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 6

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,510

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 3,243 shares sold at prices ranging from $184.50 to $185.48 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,032 $183.92 $741,565.44
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 5

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 64,753

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 4,032 shares sold at prices ranging from $183.49 to $184.48 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,286 $182.60 $782,623.60
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 4

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,785

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 4,286 shares sold at prices ranging from $182.30 to $183.03 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,619 $181.88 $1,385,743.72
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,071

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 7,619 shares sold at prices ranging from $181.30 to $182.29 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,342 $181.01 $242,915.42
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,690

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,342 shares sold at prices ranging from $180.29 to $181.19 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
November 03, 2025 Filed Nov 5, 2025 21:08 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 27,130 $23.75 $644,337.50
Disclosure

SEC source: 0001870278-25-000011 · wk-form4_1762376895.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 82,032

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 12,780 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · derivative · entry 8

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 12,780 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,183 $145.89 $172,587.87
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 7

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,902

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 1,183 shares sold at prices ranging from $145.75 to $146.04 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,944 $145.18 $717,769.92
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 6

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,085

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 4,944 shares sold at prices ranging from $144.72 to $145.57 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 8,300 $144.16 $1,196,528.00
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 5

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,029

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 8,300 shares sold at prices ranging from $143.72 to $144.71 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,391 $143.16 $1,058,095.56
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 4

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,329

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 7,391 shares sold at prices ranging from $142.70 to $143.63 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,100 $142.06 $156,266.00
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 76,720

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,100 shares sold at prices ranging from $141.58 to $142.55 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,354 $141.16 $191,130.64
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 77,820

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,354 shares sold at prices ranging from $140.58 to $141.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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September 02, 2025 Filed Sep 4, 2025 21:26 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 12,780 $30.46 $389,278.80
Disclosure

SEC source: 0001870278-25-000009 · wk-form4_1757021186.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 79,174

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

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July 15, 2025 Filed Jul 15, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 933 $102.51 $95,641.83
Disclosure

SEC source: 0001104506-25-000029 · wk-form4_1752616339.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,394

F3 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 933 shares sold at prices ranging from $102.37 to $102.70 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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July 11, 2025 Filed Jul 15, 2025 21:52 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 748 $96.41 $72,114.68
Disclosure

SEC source: 0001104506-25-000029 · wk-form4_1752616339.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,327

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · balance_after: Includes 357 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

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June 05, 2025 Filed Jun 6, 2025 20:53 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,879 $73.50 $138,106.50
Disclosure

SEC source: 0001628280-25-030045 · wk-form4_1749243207.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,718

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

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June 03, 2025 Filed Jun 4, 2025 21:38 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,448 $71.50 $103,532.00
Disclosure

SEC source: 0001628280-25-029409 · wk-form4_1749073085.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,597

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

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May 30, 2025 Filed Jun 3, 2025 20:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 20,000 $70.00 $1,400,000.00
Disclosure

SEC source: 0001628280-25-029012 · wk-form4_1748980929.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,045

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 20,000 shares sold at prices ranging from $70.00 to $70.04 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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May 30, 2025 Filed Jun 3, 2025 20:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,327 $68.56 $433,779.12
Disclosure

SEC source: 0001628280-25-029012 · wk-form4_1748980929.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,045

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 6,327 shares sold at prices ranging from $68.13 to $68.88 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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May 15, 2025 Filed May 19, 2025 21:05 UTC INSMED Inc INSM · Entity 3174 GrantStock Option (right to buy) · Derivative 27,100 $0.00 Strike: $67.22 $0.00
Disclosure

SEC source: 0001628280-25-026580 · wk-form4_1747688723.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,100

Underlying: Common Stock · 27,100 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

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May 15, 2025 Filed May 19, 2025 21:05 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 5,578 $0.00 $0.00
Disclosure

SEC source: 0001628280-25-026580 · wk-form4_1747688723.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 97,372

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

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May 14, 2025 Filed May 15, 2025 20:36 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 409 $65.61 $26,834.49
Disclosure

SEC source: 0001628280-25-025995 · wk-form4_1747341358.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,794

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

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May 13, 2025 Filed May 15, 2025 20:36 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,407 $67.81 $298,838.67
Disclosure

SEC source: 0001628280-25-025995 · wk-form4_1747341358.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,203

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

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February 06, 2025 Filed Feb 7, 2025 22:10 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 20,650 $80.90 $1,670,585.00
Disclosure

SEC source: 0001628280-25-004458 · wk-form4_1738966239.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,610

F2 · shares: Shares sold to satisfy tax withholding obligations upon the vesting of PSUs and to cover related broker fees.

F3 · price: This is the weighted average sales price representing 20,650 shares sold at prices ranging from $80.57 to $81.43 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

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February 05, 2025 Filed Feb 7, 2025 22:10 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 47,295 $0.00 $0.00
Disclosure

SEC source: 0001628280-25-004458 · wk-form4_1738966239.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,260

F1 · shares: Represents shares of common stock acquired upon vesting of Performance Stock Units (PSUs) that were originally granted on January 6, 2022, which vested on February 5, 2025 upon the achievement of the applicable performance and service conditions.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.