Calkins Daniel

SEC source: 0001104659-26-113361 · tm2626963-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 123,781

F2 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of RSUs.

SEC source: 0001104659-26-113361 · tm2626963-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 126,347

F1 · shares: The reported securities were subject to a performance restricted stock units ("RSU") award that was granted on January 21, 2026. 106,893 RSUs vested on September 30, 2026, upon the Issuer's Compensation Committee of the board of directors determining the performance criteria related to certain clinical development goals had been achieved.

SEC source: 0001104659-26-110070 · tm2626005-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,014

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: The total number of shares beneficially owned includes 831 shares of common stock acquired pursuant to the Issuer's 2018 Employee Stock Purchase Plan.

SEC source: 0001104659-26-077332 · tm2618883-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 117,238

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-26-077332 · tm2618883-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 117,295

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-26-033407 · tm269583-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 121,327

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-26-006282 · tm263949-2_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,384

F1 · shares: Restricted stock units ("RSUs") granted to the Reporting Person under the Issuer's Amended and Restated 2021 Equity Incentive Plan. Each RSU represents the contingent right to receive one share of Common Stock. The RSUs vest as to 33.3% of the RSUs on the first three anniversaries of January 21, 2026 such that the award is fully vested on January 21, 2029 (with the number of RSUs vesting on each vesting date rounded down to the nearest whole RSU, except with respect to the final vesting date on which all remaining unvested RSUs shall vest), provided that the Reporting Person continues to serve as an employee of or other service provider to the Issuer on each such vesting date.

SEC source: 0001104659-26-003787 · tm263206-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 104,719

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-124695 · tm2534347-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,758

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-092973 · tm2526868-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,838

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-092973 · tm2526868-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,863

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-062130 · tm2518795-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,920

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-062130 · tm2518795-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,945

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-051163 · tm2515719-2_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 114,055

F2 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-051163 · tm2515719-2_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,198

F1 · shares: The reported securities were subject to a performance RSU award that was granted on June 18, 2024. 150,000 RSUs vested on May 16, 2025, upon the Issuer's Compensation Committee of the board of directors determining the performance criteria of approval by the FDA of an NDA for the Company's combination therapy of avutometinib and defactinib for the treatment of low-grade serous ovarian cancer had occurred.

SEC source: 0001104659-25-027252 · tm2510143-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,348

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-027252 · tm2510143-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,374

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-25-003455 · tm253202-2_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,439

F1 · shares: Restricted stock units ("RSUs") granted to the Reporting Person under the Issuer's Amended and Restated 2021 Equity Incentive Plan. Each RSU represents the contingent right to receive one share of Common Stock. The RSUs vest as to 33.3% of the RSUs on the first three anniversaries of January 10, 2025 (the "RSU Grant Date") such that the award is fully vested on January 10, 2028 (with the number of RSUs vesting on each vesting date rounded down to the nearest whole RSU, except with respect to the final vesting date on which all remaining unvested RSUs shall vest), provided that the Reporting Person continues to serve as an employee of or other service provider to the Issuer on each such vesting date.

SEC source: 0001104659-25-002049 · tm252685-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,639

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: Includes 277 shares of common stock purchased pursuant to the Issuer's 2018 Employee Stock Purchase Plan.

SEC source: 0001104659-24-131727 · tm2432013-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,368

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-131727 · tm2432013-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,396

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-107361 · tm2425916-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,461

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F1 · balance_after: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-102450 · tm2424653-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,467

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-102450 · tm2424653-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,495

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-079089 · tm2419222-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,560

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: Includes 277 shares of common stock purchased pursuant to the Issuer's 2018 Employee Stock Purchase Plan.

SEC source: 0001104659-24-075189 · tm2418307-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,290

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-073607 · tm2417704-4_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,318

F2 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of RSUs.

SEC source: 0001104659-24-073607 · tm2417704-4_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,385

F1 · shares: Restricted stock units ("RSUs") granted to the Reporting Person under the Issuer's Amended and Restated 2021 Equity Incentive Plan. Each RSU represents the contingent right to receive one share of Common Stock. The RSUs vest as to 33.3% of the RSUs on the first three anniversaries of June 18, 2024 (the "RSU Grant Date") such that the award is fully vested on June 18, 2027 (with the number of RSUs vesting on each vesting date rounded down to the nearest whole RSU, except with respect to the final vesting date on which all remaining unvested RSUs shall vest), provided that the Reporting Person continues to serve as an employee of or other service provider to the Issuer on each such vesting date.

SEC source: 0001104659-24-044759 · tm2411345-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,535

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-039733 · tm249949-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,541

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-037352 · tm249488-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,566

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 8

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,175

Underlying: Common Stock · 1,175 shares

Expires 2034-03-11

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F1 · derivative.exercise_date: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 7

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,413

Underlying: Common Stock · 5,413 shares

Expires 2034-03-11

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F1 · derivative.exercise_date: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 6

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,875 shares

Expires 2031-12-23

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F7 · derivative.exercise_date: The canceled option was granted on December 23, 2021 and provided for vesting as to 25% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 6.25% of the shares underlying the option at the end of each successive three-month period after such date until the fourth anniversary of the grant date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 5

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 750 shares

Expires 2031-01-04

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F6 · derivative.exercise_date: The canceled option was granted on January 4, 2021 and provided for vesting as to 25% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 6.25% of the shares underlying the option at the end of each successive three-month period after such date until the fourth anniversary of the grant date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 4

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 833 shares

Expires 2030-04-01

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F5 · derivative.exercise_date: The canceled option was granted on April 1, 2020 and provided for vesting as to 25% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 6.25% of the shares underlying the option at the end of each successive three-month period after such date until the fourth anniversary of the grant date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 3

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,666 shares

Expires 2029-12-20

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F4 · derivative.exercise_date: The canceled option was granted on December 20, 2019 and provided for vesting as to 25% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 6.25% of the shares underlying the option at the end of each successive three-month period after such date until the fourth anniversary of the grant date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 2

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 833 shares

Expires 2029-06-21

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F3 · derivative.exercise_date: The canceled option was granted on June 21, 2019 and provided for vesting as to 50% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 12.5% of the shares underlying the option on each successive three month period after such date until the second anniversary of the grant date.

SEC source: 0001104659-24-034037 · tm248737-3_4seq1.xml · derivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 631 shares

Expires 2029-01-02

F1 · price: On March 11, 2024, pursuant to the Issuer's option exchange program, the Issuer canceled certain eligible unexercised options granted to the Reporting Person with an exercise price greater than $15. In exchange, the Reporting Person received (i) in the case of the canceled options that were fully vested as of March 8, 2024, a grant of 5,413 stock options that will vest in two equal installments over a two-year period from March 11, 2024 (the "Grant Date") and (ii) in the case of the canceled options there were unvested as of March 8, 2024, a grant of 1,175 stock options that will vest as to 25% on the first anniversary of the Grant Date and as to an additional 6.25% at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date, subject to the Reporting Person's continued service to the Issuer on the vesting date.

F2 · derivative.exercise_date: The canceled option was granted on January 2, 2019 and provided for vesting as to 20% of the shares underlying the option on the first anniversary of the grant date and, thereafter, vesting as to 5.0% of the shares underlying the option at the end of each successive three-month period following the first anniversary of the grant date until the fifth anniversary of the grant date.

SEC source: 0001104659-24-002584 · tm242486-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,621

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: Includes 277 shares of common stock purchased pursuant to the Issuer's 2018 Employee Stock Purchase Plan.

SEC source: 0001104659-23-130044 · tm2333888-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,350

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-128190 · tm2333521-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,375

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-111753 · tm2329107-1_4seq1.xml · derivative · entry 1

Calkins Daniel · CIK 0001951861 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2033-10-24

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of October 24, 2023 (the "Grant Date") and as to an additional 6.25% of the shares at the end of each successive three-month period following the first anniversary of the Grant Date until the fourth anniversary of the Grant Date (with the number of shares vesting on each vesting date rounded down to the nearest whole share, except with respect to the final vesting date on which all remaining unvested shares shall vest), provided that the Reporting Person continues to serve as an employee of or other service provider to the Issuer on each such vesting date.

SEC source: 0001104659-23-108316 · tm2328003-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,432

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-103536 · tm2326760-1_4seq1.xml · nonDerivative · entry 2

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,437

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-103536 · tm2326760-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,462

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-079653 · tm2320874-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,694

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: Includes 277 shares of common stock purchased pursuant to the Issuer's 2018 Employee Stock Purchase Plan.

SEC source: 0001104659-23-075801 · tm2319848-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,422

F1 · shares: - The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-042752 · tm2311917-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,397

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

SEC source: 0001104659-23-037743 · tm2310686-1_4seq1.xml · nonDerivative · entry 1

Calkins Daniel · CIK 0001951861 · Vice President of Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,472

F1 · shares: The sale reported on this Form 4 represents shares sold by the Reporting Person to satisfy statutory withholding requirements in connection with the vesting of restricted stock units.

F2 · balance_after: Includes 3,333 shares of common stock purchased pursuant to the Issuer's 2018 Employee Stock Purchase Plan.