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person · Reporting owner

Mainolfi Nello

Disclosed activity across 1 company

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31822
SEC CIK
0001821189

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Kymera Therapeutics, Inc.KYMR · Entity 3545Director · Chief Executive OfficerOctober 01, 2026October 02, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Kymera Therapeutics, Inc.

Report date October 01, 2026 · Filed October 02, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect666,568 Ending reported balance After 2026-10-01 transaction · row 7
7 source rows · reconciled sequence

Row 1 · 2026-10-01 · Exercise / conversion · Acquired 30,000 · Balance 696,568

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

Row 2 · 2026-10-01 · Sale · Disposed 3,525 · Balance 693,043

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $110.93 to $111.90, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Row 3 · 2026-10-01 · Sale · Disposed 5,506 · Balance 687,537

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $111.97 to $112.92 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Row 4 · 2026-10-01 · Sale · Disposed 4,876 · Balance 682,661

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $112.95 to $113.88 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Row 5 · 2026-10-01 · Sale · Disposed 7,601 · Balance 675,060

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F5: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $113.94 to $114.91 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Row 6 · 2026-10-01 · Sale · Disposed 8,230 · Balance 666,830

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F6: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $114.94 to $115.92, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Row 7 · 2026-10-01 · Sale · Disposed 262 · Balance 666,568

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F7: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $116.09 to $116.16 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.08 · Expires 2029-11-13Direct60,000 Reported balance After 2026-10-01 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-10-01 · Exercise / conversion · Disposed 30,000 · Balance 60,000

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F8: The shares underlying this stock option are fully vested and exercisable.

Filing footnotes · ownership attribution and instrument terms

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $110.93 to $111.90, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $111.97 to $112.92 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $112.95 to $113.88 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F5: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $113.94 to $114.91 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F6: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $114.94 to $115.92, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F7: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $116.09 to $116.16 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F8: The shares underlying this stock option are fully vested and exercisable.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · derivative · entry 8

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F8 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 262 $116.12 $30,423.44
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 7

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,568

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $116.09 to $116.16 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 8,230 $115.40 $949,742.00
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 6

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,830

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $114.94 to $115.92, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 7,601 $114.43 $869,782.43
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 5

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 675,060

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $113.94 to $114.91 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 4,876 $113.24 $552,158.24
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 682,661

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $112.95 to $113.88 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 5,506 $112.42 $618,984.52
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 687,537

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $111.97 to $112.92 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 3,525 $111.44 $392,826.00
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 693,043

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $110.93 to $111.90, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 01, 2026 Filed Oct 2, 2026 01:20 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 30,000 $2.08 $62,400.00
Disclosure

SEC source: 0001193125-26-410839 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 696,568

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

Read SEC document
July 07, 2026 Filed Jul 8, 2026 00:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 4,441 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-297817 · ownership.xml · derivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,284

Underlying: Common Stock · 4,441 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
July 07, 2026 Filed Jul 8, 2026 00:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 45,559 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-297817 · ownership.xml · derivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 45,559 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
July 07, 2026 Filed Jul 8, 2026 00:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 50,000 $119.00 $5,950,000.00
Disclosure

SEC source: 0001193125-26-297817 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,568

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

Read SEC document
July 07, 2026 Filed Jul 8, 2026 00:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 50,000 $2.08 $104,000.00
Disclosure

SEC source: 0001193125-26-297817 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 716,568

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 80,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · derivative · entry 7

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,559

Underlying: Common Stock · 80,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F8 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 3,336 $116.56 $388,840.82
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 6

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,568

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $116.29 to $116.63, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 44,050 $115.69 $5,096,069.62
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 5

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 669,904

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $115.31 to $116.23, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 24,105 $114.96 $2,771,002.33
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 713,954

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $114.29 to $115.27, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 6,626 $113.98 $755,203.65
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 738,059

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $113.36 to $114.23, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 1,883 $112.80 $212,411.06
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 744,685

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $112.28 to $113.27, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:30 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 80,000 $2.08 $166,400.00
Disclosure

SEC source: 0001193125-26-295088 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 746,568

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 24, 2026 adopted by the reporting person.

F2 · balance_after: This number includes 373 shares acquired under the Registrant's employee stock purchase plan.

Read SEC document
April 29, 2026 Filed Apr 29, 2026 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-192146 · ownership.xml · derivative · entry 5

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 215,559

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F5 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
April 29, 2026 Filed Apr 29, 2026 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 936 $82.45 $77,173.20
Disclosure

SEC source: 0001193125-26-192146 · ownership.xml · nonDerivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,195

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $82.30 to $83.07, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 29, 2026 Filed Apr 29, 2026 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 12,059 $81.70 $985,220.30
Disclosure

SEC source: 0001193125-26-192146 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 667,131

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $81.23 to $82.18, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 29, 2026 Filed Apr 29, 2026 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 17,005 $80.74 $1,372,983.70
Disclosure

SEC source: 0001193125-26-192146 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 679,190

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $80.23 to $81.215, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 29, 2026 Filed Apr 29, 2026 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 30,000 $2.08 $62,400.00
Disclosure

SEC source: 0001193125-26-192146 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 696,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
March 02, 2026 Filed Mar 4, 2026 23:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 215,000 $0.00 Strike: $90.10 $0.00
Disclosure

SEC source: 0001193125-26-091980 · ownership.xml · derivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 215,000

Underlying: Common Stock · 215,000 shares

Expires 2036-03-01

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in forty-eight (48) equal monthly installments following March 2, 2026, subject to the reporting person's continued employment through each vesting date.

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February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · derivative · entry 7

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 245,559

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F6 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 8 $93.49 $747.92
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 6

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,195

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 1,501 $92.81 $139,307.81
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 5

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 666,203

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $92.20 to $93.15, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 3,293 $91.76 $302,165.68
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 667,704

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $91.295 to $92.03, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 5,434 $90.39 $491,179.26
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 670,997

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $90.16 to $90.83, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 19,764 $89.78 $1,774,411.92
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 676,431

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $89.16 to $90.14, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
February 25, 2026 Filed Feb 25, 2026 22:24 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 30,000 $2.08 $62,400.00
Disclosure

SEC source: 0001193125-26-072155 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 696,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
January 05, 2026 Filed Jan 6, 2026 21:40 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 3,118 $0.00 Strike: $32.07 $0.00
Disclosure

SEC source: 0001193125-26-004641 · ownership.xml · derivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 446,882

Underlying: Common Stock · 3,118 shares

Expires 2033-03-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in thirty-six (36) equal monthly installments following March 1, 2023, subject to the reporting person's continued employment through each vesting date.

Read SEC document
January 05, 2026 Filed Jan 6, 2026 21:40 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 3,118 $32.07 $99,994.26
Disclosure

SEC source: 0001193125-26-004641 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 666,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 31, 2025 Filed Dec 31, 2025 22:23 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-25-338415 · ownership.xml · derivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 275,559

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F4 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
December 31, 2025 Filed Dec 31, 2025 22:23 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 6,014 $78.52 $472,211.46
Disclosure

SEC source: 0001193125-25-338415 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 663,077

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $78.44 to $78.74, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 31, 2025 Filed Dec 31, 2025 22:23 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 23,986 $77.95 $1,869,727.89
Disclosure

SEC source: 0001193125-25-338415 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 669,091

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $77.44 to $78.43, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
December 31, 2025 Filed Dec 31, 2025 22:23 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 30,000 $2.08 $62,400.00
Disclosure

SEC source: 0001193125-25-338415 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 693,077

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
December 17, 2025 Filed Dec 17, 2025 23:07 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 2,595 $0.00 Strike: $38.53 $0.00
Disclosure

SEC source: 0001193125-25-323092 · ownership.xml · derivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 272,505

Underlying: Common Stock · 2,595 shares

Expires 2032-03-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
December 17, 2025 Filed Dec 17, 2025 23:07 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 2,595 $38.53 $99,985.35
Disclosure

SEC source: 0001193125-25-323092 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 663,077

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 08, 2025 Filed Dec 8, 2025 23:09 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 100,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-25-311504 · ownership.xml · derivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 305,559

Underlying: Common Stock · 100,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
December 08, 2025 Filed Dec 8, 2025 23:09 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 100,000 $89.17 $8,917,000.00
Disclosure

SEC source: 0001193125-25-311504 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 660,482

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
December 08, 2025 Filed Dec 8, 2025 23:09 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 100,000 $2.08 $208,000.00
Disclosure

SEC source: 0001193125-25-311504 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 760,482

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
October 29, 2025 Filed Oct 29, 2025 21:19 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-25-256673 · ownership.xml · derivative · entry 5

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 405,559

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F5 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
October 29, 2025 Filed Oct 29, 2025 21:19 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 3,627 $61.46 $222,906.72
Disclosure

SEC source: 0001193125-25-256673 · ownership.xml · nonDerivative · entry 4

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 660,482

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.37 to $61.82, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 29, 2025 Filed Oct 29, 2025 21:19 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 24,511 $61.02 $1,495,626.90
Disclosure

SEC source: 0001193125-25-256673 · ownership.xml · nonDerivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 664,109

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.37 to $61.34, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 29, 2025 Filed Oct 29, 2025 21:19 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 1,862 $59.72 $111,203.30
Disclosure

SEC source: 0001193125-25-256673 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 688,620

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.35 to $60.01, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
October 29, 2025 Filed Oct 29, 2025 21:19 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionCommon Stock 30,000 $2.08 $62,400.00
Disclosure

SEC source: 0001193125-25-256673 · ownership.xml · nonDerivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 690,482

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document
September 16, 2025 Filed Sep 16, 2025 20:11 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $2.08 $0.00
Disclosure

SEC source: 0001193125-25-204997 · ownership.xml · derivative · entry 3

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 435,559

Underlying: Common Stock · 30,000 shares

Expires 2029-11-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

F2 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
September 16, 2025 Filed Sep 16, 2025 20:11 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 SaleCommon Stock 30,000 $49.00 $1,470,000.00
Disclosure

SEC source: 0001193125-25-204997 · ownership.xml · nonDerivative · entry 2

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 660,482

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 6, 2024 adopted by the reporting person.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.