Pearce Samantha

SEC source: 0001805688-26-000014 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,131

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001805688-26-000012 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,911

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

F2 · balance_after: The Reporting Person acquired 166 ordinary shares under a Section 423 Employee Stock Purchase Plan on May 29, 2026.

SEC source: 0001805688-26-000008 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 6,907 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vested in 36 equal monthly installments thereafter. The option was fully vested as of March 2, 2024.

SEC source: 0001805688-26-000008 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,272

SEC source: 0001805688-26-000008 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,179

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001805688-26-000006 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,272

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001805688-26-000004 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,775

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2026, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001805688-26-000002 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,993

F3 · kind: Shares withheld from the vesting and distribution of performance share awards to satisfy the reporting person's tax obligations.

SEC source: 0001805688-26-000002 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,592

F1 · kind: Represents ordinary shares of the Issuer delivered pursuant to the terms of performance share awards made to the reporting person on March 3, 2023. The performance-based vesting requirements applicable to such awards were satisfied on January 16, 2026, which represents the date on which the level of performance attained was certified.

F2 · balance_after: The Reporting Person acquired 140 ordinary shares under a Section 423 Employee Stock Purchase Plan on November 28, 2025.

SEC source: 0001765581-25-000051 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,815

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

F2 · balance_after: The Reporting Person acquired 166 ordinary shares under a Section 423 Employee Stock Purchase Plan on May 30, 2025.

SEC source: 0001765581-25-000029 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,226

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-25-000016 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,131

F2 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units will vest in full on June 30, 2026.

SEC source: 0001765581-25-000016 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,353

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2025, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001805688-25-000003 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,412

F3 · kind: Shares to be withheld from the vesting and distribution of performance award shares to satisfy the reporting person's tax obligations.

SEC source: 0001805688-25-000003 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,777

F1 · kind: Represents ordinary shares of Jazz Pharamceuticals that will be delivered pursuant to the terms of performance share awards made to the reporting person on March 3, 2022. The performance-based vesting requirements applicable to such awards were satisfied on January 17, 2025, which represents the date on which the level of performance attained was certified.

F2 · balance_after: The Reporting Person acquired 166 ordinary shares under a Section 423 Employee Stock Purchase Plan on November 29, 2024.

SEC source: 0001765581-24-000072 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,078

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of August 5, 2024, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

F2 · balance_after: Includes 160 ordinary shares acquired on May 31, 2024 under a Section 423 Employee Stock Purchase Plan.

SEC source: 0001765581-24-000035 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,922

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-24-000022 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,396

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2024, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001784606-24-000012 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,331

F2 · kind: Shares to be withheld from the vesting and distribution of performance award shares to satisfy the reporting person's tax obligations.

SEC source: 0001784606-24-000012 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,369

F1 · kind: Represents ordinary shares of Jazz Pharamceuticals that will be delivered pursuant to the terms of performance share awards made to the reporting person on May 5, 2021. The performance-based vesting requirements applicable to such awards were satisfied on January 17, 2024, which represents the date on which the level of performance attained was certified.

SEC source: 0001765581-23-000019 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,159

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000019 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,179

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000008 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,907

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-23-000008 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000008 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000004 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,438

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-23-000004 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000004 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000140 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,969

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000140 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000140 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000120 · edgardoc.xml · derivative · entry 6

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000120 · edgardoc.xml · derivative · entry 5

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,031

Underlying: Ordinary Shares · 532 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000120 · edgardoc.xml · nonDerivative · entry 4

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

SEC source: 0001765581-22-000120 · edgardoc.xml · nonDerivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-22-000120 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

SEC source: 0001765581-22-000120 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,841

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-22-000109 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,563

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000109 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000109 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000075 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,094

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000075 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000075 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-22-000071 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,625

Underlying: Ordinary Shares · 532 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000071 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000071 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,841

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-22-000065 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,157

Underlying: Ordinary Shares · 8,508 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000065 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

SEC source: 0001765581-22-000065 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,817

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-22-000063 · edgardoc.xml · derivative · entry 4

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,665

Underlying: Ordinary Shares · 5,835 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options are granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in 36 equal monthly installments thereafter.