MORE ROBERT J

SEC source: 0001628280-26-056108 · wk-form4_1786559443.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 517,917

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred by the Reporting Person for no consideration to APNG 1 in connection with the vesting of restricted stock unit (RSU) awards.

F2 · ownership.nature: The shares are held by APNG 1. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG I. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1; however, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001628280-26-056108 · wk-form4_1786559443.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,656

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred by the Reporting Person for no consideration to APNG 1 in connection with the vesting of restricted stock unit (RSU) awards.

SEC source: 0001193125-26-251534 · ownership.xml · derivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,160

Underlying: Common Stock · 13,160 shares

Expires 2036-05-27

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 28, 2026, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

SEC source: 0001628280-26-038964 · wk-form4_1780010697.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2036-05-26

F4 · shares: The shares subject to the stock option will vest and become exercisable in full on May 27, 2027.

SEC source: 0001628280-26-038964 · wk-form4_1780010697.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,656

F1 · kind: Acquisition of restricted stock units (RSUs) pursuant to the Issuer's Equity Incentive Plan.

F2 · shares: The RSUs will vest in full on May 27, 2027.

SEC source: 0001193125-25-327254 · ownership.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · See footnote

Disclosed balance after: 3,823,425

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by Alta Partners NextGen Fund II, L.P. ("APNG II") on June 26, 2025.

F2 · ownership.nature: These securities are held directly by APNG II. The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0001193125-25-297551 · ownership.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · See footnote

Disclosed balance after: 3,833,425

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by Alta Partners NextGen Fund II, L.P. ("APNG II") on June 26, 2025.

F2 · price: Represents the weighted average sale price for the entire number of shares sold. The actual sale prices range between $20.25 to $21.24. Detailed information on the exact number of shares sold at each sale price can be obtained from the Issuer upon request.

F3 · ownership.nature: These securities are held directly by APNG II. The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0001628280-25-030306 · wk-form4_1749508754.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 509,917

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred by the Reporting Person for no consideration to APNG 1 in connection with the vesting of RSU awards. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

F2 · ownership.nature: The shares are held by APNG 1. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG I. The Reporting Person may be deemed to beneficially own the shares held by APNG 1, and disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001628280-25-030306 · wk-form4_1749508754.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,656

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred by the Reporting Person for no consideration to APNG 1 in connection with the vesting of RSU awards. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the Reporting Person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001628280-25-028894 · wk-form4_1748906520.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2035-05-29

F4 · shares: The shares subject to the stock option will vest and become exercisable in full on May 30, 2026.

SEC source: 0001628280-25-028894 · wk-form4_1748906520.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,683

F1 · kind: Acquisition of restricted stock units (RSUs) pursuant to the Issuer's Equity Incentive Plan.

F2 · shares: The RSUs will vest in full on May 30, 2026.

SEC source: 0000950170-25-080230 · ownership.xml · derivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,200

Underlying: Common Stock · 22,200 shares

Expires 2035-05-28

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 29, 2025, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

SEC source: 0001628280-24-026207 · wk-form4_1717430899.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2034-05-29

SEC source: 0001628280-24-026207 · wk-form4_1717430899.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 46,683

SEC source: 0000950170-24-067361 · ownership.xml · derivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,600

Underlying: Common Stock · 18,600 shares

Expires 2034-05-28

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 29, 2024, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

SEC source: 0001628280-23-034785 · wk-form4_1697825747.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 495,890

F2 · shares: Shares transferred for no consideration to APNG 1 upon vesting of an RSU award held by the Reporting Person for the benefit of APNG 1.

F3 · ownership.nature: The shares are held by APNG 1. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG I. The Reporting Person may be deemed to beneficially own the shares held by APNG 1, and disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001628280-23-034785 · wk-form4_1697825747.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,683

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred for no consideration to APNG 1 in connection with the vesting of an RSU award. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

F1 · shares: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred for no consideration to APNG 1 in connection with the vesting of an RSU award. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001209191-23-033775 · doc4.xml · derivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,500

Underlying: Common Stock · 14,500 shares

Expires 2033-05-30

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following May 31, 2023, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

SEC source: 0001209191-23-031845 · doc4.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,054

Underlying: Common Stock · 12,054 shares

Expires 2033-05-21

SEC source: 0001209191-23-031845 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,088

SEC source: 0001209191-22-036981 · doc4.xml · derivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,500

Underlying: Common Stock · 14,500 shares

Expires 2032-06-12

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's Non-Employee Director Compensation Program. 1/12th of the total number of shares of common stock subject to the option vest monthly following June 13, 2022, the date of grant. In the event the next occurring annual meeting of the Issuer's stockholders occurs prior to the first anniversary of the date of grant, any remaining unvested portion of the option will vest on the date of such annual meeting of the Issuer's stockholders, subject to the Reporting Person's continuous service to the Issuer through each vesting date.

SEC source: 0001209191-22-036296 · doc4.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 489,485

F2 · shares: Shares transferred for no consideration to APNG 1 upon vesting of an RSU award held by the Reporting Person for the benefit of APNG 1.

F3 · ownership.nature: The shares are held by APNG 1. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG I. The Reporting Person may be deemed to beneficially own the shares held by APNG 1, and disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-036296 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,061

F1 · kind: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred for no consideration to APNG 1 in connection with the vesting of an RSU award. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

F1 · shares: Shares held by the Reporting Person for the benefit of Alta Partners NextGen Fund I, L.P. (APNG 1) were transferred for no consideration to APNG 1 in connection with the vesting of an RSU award. The Reporting Person is a managing director of Alta Partners NextGen Fund I Management, LLC, which is the general partner of APNG 1. As such, the Reporting Person may be deemed to beneficially own the shares held by APNG 1. However, the Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001209191-22-031950 · doc4.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,810

Underlying: Common Stock · 12,810 shares

Expires 2032-05-22

SEC source: 0001209191-22-031950 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,435

SEC source: 0000899243-21-036431 · doc4.xml · derivative · entry 4

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 662,752 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F1 · derivative.exercise_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F1 · derivative.expiration_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-21-036431 · doc4.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 3,148,365 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F1 · derivative.exercise_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F1 · derivative.expiration_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-21-036431 · doc4.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 4,080,296

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-21-036431 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 3,924,046

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The Reporting Person is a managing director of the general partner of APNG II and shares voting and investment control with respect to the shares held by APNG II. The Reporting Person disclaims beneficial ownership of all shares held by APNG II, except to the extent of his pecuniary interest therein.

SEC source: 0001209191-21-049147 · doc4.xml · nonDerivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,030

F6 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.22 to $37.99, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-049147 · doc4.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,378

F6 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.19 to $37.15, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-047285 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,029

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.18 to $36.00, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-045554 · doc4.xml · nonDerivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,699

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.91 to $46.60, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-045554 · doc4.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,589

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.84 to $45.77, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-045554 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,575

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $43.81 to $44.80, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-049147 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,700

F1 · kind: On July 1, 2021, the reporting person became entitled to receive 1,671 shares of the Issuer's common stock pursuant to an "earn-out" right in a letter agreement (the "Letter Agreement") entered into in connection with the Issuer's acquisition of all equity interests of TomegaVax, Inc. ("TomegaVax") on September 12, 2016 (the "TomegaVax Merger"). The Letter Agreement provides for certain payments to TomegaVax's former stockholders, for no additional consideration, prior to September 2024, in each case so long as the Issuer is continuing to pursue the development of the TomegaVax technology.

F2 · kind: Under the terms of the Letter Agreement, the Issuer will be required to pay to the former stockholders of TomegaVax milestone payments of up to an aggregate of $30.0 million if the per-share price of the Issuer's publicly traded common stock, or implied price per share of the Issuer's Series A-1 convertible preferred stock (or common stock upon conversion) upon a certain asset sale, merger or stock sale, is at least $45 (as adjusted in the case of any stock dividend, stock split or other similar recapitalization), with the amount of such payments determined by the share price and/or the stage of the Issuer's clinical development at the time of the relevant event triggering the payment. The share price of the Issuer's publicly traded common stock will be determined using the average of the daily volume-weighted average trading price of the Issuer's common stock for each trading day during a consecutive 90-day period.

F3 · kind: The foregoing payments are payable (i) during any date after the completion of an initial public offering by the Issuer or any successor or affiliate controlling the TomegaVax technology, provided that no payment will be due before the first anniversary of the initial public offering, (ii) upon the sale of all assets related to the TomegaVax technology or (iii) upon a merger or stock sale of the Issuer or any successor or affiliate controlling the TomegaVax technology, in each case subject to certain conditions with respect to the timing of the payments. The payments under the Letter Agreement can be made in cash or shares of the Issuer's common stock, at the discretion of the Issuer's board of directors. On February 24, 2021, the Issuer achieved one of the milestones related to the specified per-share price of its common stock, which resulted in a $10.0 million payable to TomegaVax's former stockholders within 90 business days of achieving such milestone.

F4 · kind: The number of shares issuable pursuant to the earn-out right was determined on July 1, 2021 (90 business days after the achievement of such milestone) based on the closing price of the Issuer's common stock on such date, as provided in the Letter Agreement. On July 9, 2021, the Issuer completed the milestone payment to the former TomegaVax stockholders, including the reporting person, through a combination of cash payment and shares of common stock as determined by the Issuer's board of directors. The reporting person's right to receive additional shares became fixed and irrevocable on September 12, 2016, the effective date of the TomegaVax Merger.

F5 · kind: The remaining $20.0 million in milestone payments will be triggered if (i) the per-share price of the Issuer's publicly traded common stock is at least $45 (as adjusted in the case of any stock dividend, stock split or other similar recapitalization) and upon the achievement of a certain milestone related to the stage of the Issuer's clinical development at the time of the relevant event triggering the payment or (ii) the per-share price of the Issuer's publicly traded common stock is at least $90 (as adjusted in the case of any stock dividend, stock split or other similar recapitalization). The foregoing description of the terms of the Letter Agreement is qualified in its entirety by reference to the full text of the Letter Agreement, a copy of which was filed as Exhibit 10.31 to the Issuer's Annual Report on Form 10-K for the year-ended December 31, 2020 filed with the Securities and Exchange Commission on February 25, 2021.

SEC source: 0001209191-21-042116 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,369

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $43.64 to $44.31, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-038772 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,039

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.02 to $45.00, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-035709 · doc4.xml · derivative · entry 3

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,748

Underlying: Common Stock · 6,748 shares

Expires 2031-05-20

SEC source: 0001209191-21-035709 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,709

SEC source: 0001209191-21-035596 · doc4.xml · nonDerivative · entry 2

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 89,335

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.22 to $45.03, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-21-035596 · doc4.xml · nonDerivative · entry 1

MORE ROBERT J · CIK 0001207792 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,430

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 24, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $43.16 to $44.13, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

F3 · balance_after: Includes 30,354 shares received in a pro-rata distribution from Alta Partners NextGen Fund I, L.P. (APNG 1) which was effected on April 5, 2021.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 19

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $121.60 - $122.02, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 18

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 605

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $120.53 - $121.38, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 17

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,605

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $119.29 - $120.22, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 16

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,205

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $118.27 - $119.25, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 15

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,505

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $117.27 - $118.18, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 14

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,205

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $116.25 - $117.10, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 13

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,076

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $115.25 - $116.23, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-21-018405 · doc4.xml · nonDerivative · entry 12

MORE ROBERT J · CIK 0001207792 · member - potential 10% group

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,676