person · Reporting owner

SCHULER JACK W

Disclosed activity across 9 companies

Tapewire entity: 23810
SEC CIK: 0001021412

Reported relationships

Latest disclosed role at each company.

Company	Last reported as	Report date	Published
Accelerate Diagnostics, IncAXDX · Entity 78156	Director · 10% owner	December 03, 2024	December 03, 2024
Aspira Women's Health Inc.AWHL · Entity 7871	10% owner	June 05, 2026	June 09, 2026
BIODESIX INCBDSX · Entity 6053	10% owner · Emeritus Director	August 12, 2026	August 13, 2026
BIOLASE, INCBIOL · Entity 11470	10% owner	February 11, 2020	May 15, 2020
Neos Therapeutics, Inc.NEOS · Entity 141061	10% owner	February 17, 2017	February 17, 2017
QUIDEL CORP /DE/QDEL · Entity 126712	Director · 10% owner	May 14, 2020	May 18, 2020
STERICYCLE INCSRCL · Entity 80873	Director	April 30, 2018	May 02, 2018
YIELD10 BIOSCIENCE, INC.YTEN · Entity 88195	10% owner	December 20, 2023	May 17, 2024

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Accelerate Diagnostics, Inc

Report date December 03, 2024 · Filed December 03, 2024

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler Living Trust	8,310,388	Reported balance After 2024-12-03 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2024-12-03 · Sale · Disposed 200,000 · Balance 8,310,388 F1: Represents shares sold by the reporting person to John Patience, a member of the issuer's board of directors, in a private transaction for tax planning purposes. F2: The reporting person has sole voting and dispositive power with respect to such shares in his capacity as trustee of the trust.
Common StockSEC Table I · non-derivative	Direct	20,225	Reported balance Holding disclosure · report date 2024-12-03 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 20,225
Common StockSEC Table I · non-derivative	IndirectBy Spouse	5,497	Reported balance Holding disclosure · report date 2024-12-03 · row 3 Holding and transaction disclosures are not merged. 1 source row Row 3 · Balance 5,497 F3: The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

Filing footnotes · ownership attribution and instrument terms

F1: Represents shares sold by the reporting person to John Patience, a member of the issuer's board of directors, in a private transaction for tax planning purposes.

F2: The reporting person has sole voting and dispositive power with respect to such shares in his capacity as trustee of the trust.

F3: The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

Aspira Women's Health Inc.

Report date June 05, 2026 · Filed June 09, 2026

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler Living Trust	4,046,051	Reported balance After 2026-06-05 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2026-06-05 · Purchase · Acquired 222,222 · Balance 4,046,051 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.75 · Expires 2029-06-05	IndirectBy Jack W. Schuler Living Trust	300,000	Reported balance After 2026-06-05 transaction · row 3 Instrument identity requires review; Table II rows are not merged. 1 source row Row 3 · 2026-06-05 · Purchase · Acquired 300,000 · Balance 300,000 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.75 · Expires 2030-09-17	IndirectBy Jack W. Schuler Living Trust	833,333	Reported balance Holding disclosure · report date 2026-06-05 · row 4 Instrument identity requires review; Table II rows are not merged. 1 source row Row 4 · Balance 833,333 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.25 · Expires 2030-03-12	IndirectBy Jack W. Schuler Living Trust	1,801,265	Reported balance Holding disclosure · report date 2026-06-05 · row 6 Instrument identity requires review; Table II rows are not merged. 1 source row Row 6 · Balance 1,801,265 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.13 · Expires 2029-07-26	IndirectBy Jack W. Schuler Living Trust	28,500	Reported balance Holding disclosure · report date 2026-06-05 · row 7 Instrument identity requires review; Table II rows are not merged. 1 source row Row 7 · Balance 28,500 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.13 · Expires 2029-01-26	IndirectBy Jack W. Schuler Living Trust	8,888	Reported balance Holding disclosure · report date 2026-06-05 · row 8 Instrument identity requires review; Table II rows are not merged. 1 source row Row 8 · Balance 8,888 F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.
Common StockSEC Table I · non-derivative	Direct	6,536	Reported balance Holding disclosure · report date 2026-06-05 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 6,536
Warrant (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.25 · Expires 2027-07-09	Direct	6,536	Reported balance Holding disclosure · report date 2026-06-05 · row 5 Instrument identity requires review; Table II rows are not merged. 1 source row Row 5 · Balance 6,536

Filing footnotes · ownership attribution and instrument terms

F1: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust") and in such capacity may be deemed to beneficially own the securities held by the Living Trust.

BIODESIX INC

Report date August 12, 2026 · Filed August 13, 2026

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler Living Trust	555,810	Reported balance After 2026-08-12 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2026-08-12 · Purchase · Acquired 15,000 · Balance 555,810 F1: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.00 to $24.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. F2: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler 2026 GRAT	1,800,000	Reported balance Holding disclosure · report date 2026-08-12 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 1,800,000 F3: Jack W. Schuler is the sole trustee of the Jack W. Schuler 2026 GRAT.

Filing footnotes · ownership attribution and instrument terms

F1: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $24.00 to $24.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

F2: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

F3: Jack W. Schuler is the sole trustee of the Jack W. Schuler 2026 GRAT.

BIOLASE, INC

Report date February 11, 2020 · Filed May 15, 2020

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Trust	739,820	Reported balance After 2020-02-11 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2020-02-11 · Sale · Disposed 1,307,931 · Balance 739,820 F1: These figures reflect a 1-for-5 reverse stock split effected by the Issuer on May 10, 2018. F2: The Common Stock is held directly by the Jack W. Schuler Living Trust (the "Trust"). Mr. Schuler serves as sole trustee to the Trust.
Common StockSEC Table I · non-derivative	IndirectBy Spouse	20,000	Reported balance Holding disclosure · report date 2020-02-11 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 20,000 F1: These figures reflect a 1-for-5 reverse stock split effected by the Issuer on May 10, 2018.

Filing footnotes · ownership attribution and instrument terms

F1: These figures reflect a 1-for-5 reverse stock split effected by the Issuer on May 10, 2018.

F2: The Common Stock is held directly by the Jack W. Schuler Living Trust (the "Trust"). Mr. Schuler serves as sole trustee to the Trust.

Neos Therapeutics, Inc.

Report date February 17, 2017 · Filed February 17, 2017

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy the Jack W Schuler Living Trust	2,338,671	Reported balance Holding disclosure · report date 2017-02-17 · row 1 Holding and transaction disclosures are not merged. 1 source row Row 1 · Balance 2,338,671 F1: Jack W. Schuler is the sole trustee of the Jack W Schuler Living Trust. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: Jack W. Schuler is the sole trustee of the Jack W Schuler Living Trust. The Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein.

QUIDEL CORP /DE/

Report date May 14, 2020 · Filed May 18, 2020

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	3,103,249	Reported balance After 2020-05-14 transaction · row 1 Account or security details depend on footnotes; rows are not merged. 1 source row Row 1 · 2020-05-14 · Exercise / conversion · Acquired 2,100 · Balance 3,103,249 F1: Reflects release of restricted stock units that were previously reported on Form 4. F2: In addition to the shares reported on this Form 4 as directly owned by the Reporting Person, 65,000 shares are held indirectly by the Reporting Person's spouse and 1,105,263 shares are held indirectly by the Schuler Family Foundation. The Reporting Person disclaims all beneficial ownership of the shares held by his spouse and the Schuler Family Foundation, except to the extent of his pecuniary interest, if any.
Restricted Stock UnitsSEC Table II · derivative / convertible security	Direct	0	Reported balance After 2020-05-14 transaction · row 2 Instrument identity requires review; Table II rows are not merged. 1 source row Row 2 · 2020-05-14 · Exercise / conversion · Disposed 2,100 · Balance 0 F3: Restricted stock units convert into common stock on a one-for-one basis. F4: On May 14, 2019, the reporting person was granted 2,100 restricted stock units vesting on the first anniversary of the grant date.

Filing footnotes · ownership attribution and instrument terms

F1: Reflects release of restricted stock units that were previously reported on Form 4.

F2: In addition to the shares reported on this Form 4 as directly owned by the Reporting Person, 65,000 shares are held indirectly by the Reporting Person's spouse and 1,105,263 shares are held indirectly by the Schuler Family Foundation. The Reporting Person disclaims all beneficial ownership of the shares held by his spouse and the Schuler Family Foundation, except to the extent of his pecuniary interest, if any.

F3: Restricted stock units convert into common stock on a one-for-one basis.

F4: On May 14, 2019, the reporting person was granted 2,100 restricted stock units vesting on the first anniversary of the grant date.

STERICYCLE INC

Report date April 30, 2018 · Filed May 02, 2018

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00	Direct	2,078	Reported balance After 2018-04-30 transaction · row 1 Instrument identity requires review; Table II rows are not merged. 1 source row Row 1 · 2018-04-30 · Grant · Acquired 170 · Balance 2,078 F1: In accordance with the Stericycle, Inc. Directors Deferred Stock Plan, the reporting person has elected to defer actual receipt of the shares to which such person would otherwise be entitled upon vesting until such person's separation of service from the issuer.

Filing footnotes · ownership attribution and instrument terms

F1: In accordance with the Stericycle, Inc. Directors Deferred Stock Plan, the reporting person has elected to defer actual receipt of the shares to which such person would otherwise be entitled upon vesting until such person's separation of service from the issuer.

YIELD10 BIOSCIENCE, INC.

Report date December 20, 2023 · Filed May 17, 2024

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler Living Trust	63,789	Reported balance After 2023-12-20 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2023-12-20 · Sale · Disposed 36,000 · Balance 63,789 F1: This late filing is due to an inadvertent administrative error. F2: On May 2, 2024 the Issuer effected a 1-for-24 reverse stock split of its common stock (the "Reverse Stock Split"). The amount of securities beneficially owned following the transaction reported herein has been adjusted and approximated to reflect the Reverse Stock Split. F3: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

Filing footnotes · ownership attribution and instrument terms

F1: This late filing is due to an inadvertent administrative error.

F2: On May 2, 2024 the Issuer effected a 1-for-24 reverse stock split of its common stock (the "Reverse Stock Split"). The amount of securities beneficially owned following the transaction reported herein has been adjusted and approximated to reflect the Reverse Stock Split.

F3: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

SOLENO THERAPEUTICS INC

Report date December 09, 2022 · Filed May 15, 2023

Section 16 reporting ended · disclosed 2023-05-15. Current position is not established by this disclosure.

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	IndirectBy Jack W. Schuler Living Trust	36,595	Reported balance After 2022-12-09 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 1 · 2022-12-09 · Sale · Disposed 10,000 · Balance 36,595 F1: This late filing is due to an inadvertent administrative error. F2: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust.

Filing footnotes · ownership attribution and instrument terms

F1: This late filing is due to an inadvertent administrative error.

F2: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust.

Transaction history

JSON API

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction date	Company	Activity / security	Shares / units	Reported price	Reported value	Details
November 30, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.99	$9,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 24 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 106,595 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 29, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.47	$7,410.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 27 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 717,858 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 29, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.01	$10,100.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 23 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 116,595 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 28, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.44	$7,320.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 26 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 720,858 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 28, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.05	$10,500.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 22 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 126,595 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 25, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.07	$10,700.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 21 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 136,595 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 23, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,400	$1.11	$11,544.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 20 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 146,595 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 22, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.07	$10,700.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 19 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 156,995 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 21, 2022 Filed Nov 21, 2022 23:03 UTC	BIODESIX INC BDSX · Entity 6053	PurchaseCommon Stock	8,695,652	$1.15	$9,999,999.80	Disclosure SEC source: 0001140361-22-042601 · form4.xml · nonDerivative · entry 1 SCHULER JACK W · CIK 0001021412 · Director · 10% owner 10b5-1 filing: Not disclosed Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 19,952,112 F1 · ownership.direct: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust. F1 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust. Read SEC document
November 21, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	14,531	$1.13	$16,420.03	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 18 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 166,995 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 18, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	28,474	$1.15	$32,745.10	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 17 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 181,526 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 17, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	11,442	$1.15	$13,158.30	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 16 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 210,000 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 16, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	116,882	$1.26	$147,271.32	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 15 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 221,442 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 15, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.72	$8,160.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 25 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 723,858 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 15, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.09	$10,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 14 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 338,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 14, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.70	$8,100.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 24 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 726,858 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 14, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.07	$10,700.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 13 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 348,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 09, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,400	$2.41	$8,194.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 23 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 729,858 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 09, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.94	$9,400.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 12 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 358,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 08, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.49	$7,470.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 22 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 733,258 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 08, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.99	$9,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 11 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 368,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 07, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.45	$7,350.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 21 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 736,258 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 07, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.99	$9,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 10 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 378,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 04, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	1,400	$2.53	$3,542.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 20 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 739,258 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 04, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.99	$9,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 9 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 388,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 03, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.01	$10,100.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 8 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 398,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 02, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.81	$8,430.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 19 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 740,658 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 02, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.97	$9,700.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 7 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 408,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 01, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.97	$8,910.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 18 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 743,658 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
November 01, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$0.99	$9,900.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 6 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 418,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 31, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	9,851	$3.01	$29,651.51	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 17 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 746,658 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 31, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.00	$10,000.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 5 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 428,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 28, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	4,158	$3.01	$12,515.58	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 16 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 756,509 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 28, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	10,000	$1.08	$10,800.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 4 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 438,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 27, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	4,000	$3.03	$12,120.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 15 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 760,667 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 27, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	9,100	$1.16	$10,556.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 3 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 448,324 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 26, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	7,420	$3.03	$22,482.60	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 14 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 764,667 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 26, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	8,842	$1.26	$11,140.92	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 2 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 457,424 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 25, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,141	$3.07	$9,642.87	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 13 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 772,087 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 24, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	4,625	$3.06	$14,152.50	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 12 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 775,228 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 21, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	20,338	$3.09	$62,844.42	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 11 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 779,853 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 20, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	4,200	$3.14	$13,188.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 10 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 800,191 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 19, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	4,259	$3.22	$13,713.98	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 9 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 804,391 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 18, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	13,822	$3.35	$46,303.70	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 8 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 808,650 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 17, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	25,343	$3.34	$84,645.62	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 7 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 822,472 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 14, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$3.20	$9,600.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 6 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 847,815 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 13, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	3,000	$2.88	$8,640.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 5 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 850,815 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 13, 2022 Filed May 15, 2023 20:00 UTC	SOLENO THERAPEUTICS INC SLNO · Entity 46432	SaleCommon Stock	400	$1.52	$608.00	Disclosure SEC source: 0001175707-23-000146 · form4.xml · nonDerivative · entry 1 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 466,266 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 12, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	1,200	$2.85	$3,420.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 4 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 853,815 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document
October 11, 2022 Filed May 9, 2023 12:09 UTC	YIELD10 BIOSCIENCE, INC. YTEN · Entity 88195	SaleCommon Stock	900	$2.96	$2,664.00	Disclosure SEC source: 0001175707-23-000121 · form4.xml · nonDerivative · entry 3 SCHULER JACK W · CIK 0001021412 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Jack W. Schuler Living Trust Disclosed balance after: 855,015 F1 · date: This late filing is due to an inadvertent administrative error. F2 · ownership.nature: Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust (the "Living Trust"), and in such capacity may be deemed to beneficially own the Common Stock held by the Living Trust. Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.