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Griffiths Richard Ian

Disclosed activity across 1 company

Tapewire entity
23693
SEC CIK
0001846370

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Silence Therapeutics plcSLN · Entity 502810% ownerAugust 10, 2026August 13, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Silence Therapeutics plc

Report date August 10, 2026 · Filed August 13, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote7,488,660 Reported balance After 2026-08-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-08-10 · Sale · Acquired 2,792,826 · Balance 7,488,660

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $15.58IndirectSee footnote7,388,660 Reported balance After 2026-08-10 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-08-10 · Sale · Acquired 100,000 · Balance 7,388,660

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.09IndirectSee footnote7,338,660 Reported balance After 2026-08-10 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-08-10 · Sale · Acquired 50,000 · Balance 7,338,660

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.35IndirectSee footnote7,335,160 Reported balance After 2026-08-10 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-08-10 · Sale · Acquired 3,500 · Balance 7,335,160

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote6,535,160 Reported balance After 2026-08-10 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-08-10 · Sale · Acquired 800,000 · Balance 6,535,160

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote6,153,160 Reported balance After 2026-08-10 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-08-10 · Sale · Acquired 382,000 · Balance 6,153,160

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.09IndirectSee footnote5,682,340 Reported balance After 2026-08-10 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-08-10 · Sale · Acquired 470,820 · Balance 5,682,340

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote5,077,166 Reported balance After 2026-08-10 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-08-10 · Sale · Acquired 605,174 · Balance 5,077,166

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote4,957,166 Reported balance After 2026-08-10 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2026-08-10 · Sale · Acquired 120,000 · Balance 4,957,166

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.35IndirectSee footnote4,897,166 Reported balance After 2026-08-10 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2026-08-10 · Sale · Acquired 60,000 · Balance 4,897,166

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

American Depositary SharesSEC Table II · derivative / convertible security · Conversion / exercise price $16.00IndirectSee footnote4,797,166 Reported balance After 2026-08-10 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2026-08-10 · Sale · Acquired 100,000 · Balance 4,797,166

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2: The securities were sold by Cream Capital Limited ("CCL"), Blake Holdings Limited ("BHL"), Ora Ventures Limited ("OVL"), Ora Capital Limited ("OCL), Sarossa Plc ("SAR"), Pinkeys Limited ("PKL") and Mr. Griffiths personally. Mr Griffiths is a director and the controlling shareholder of CCL, BHL, OVL and OCL and the controlling shareholder of SAR and PKL. Mr. Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 13, 2025 Filed May 15, 2025 20:51 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 94,234 Not disclosed Strike: $4.01 Not disclosed
Disclosure

SEC source: 0001104659-25-049572 · tm2515252-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,065,087

Underlying: Ordinary Shares · 282,702 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
May 07, 2025 Filed May 8, 2025 11:08 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.81 Not disclosed
Disclosure

SEC source: 0001104659-25-045874 · tm2514463-1_4seq1.xml · derivative · entry 3

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,970,853

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
May 06, 2025 Filed May 8, 2025 11:08 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 100,000 Not disclosed Strike: $3.96 Not disclosed
Disclosure

SEC source: 0001104659-25-045874 · tm2514463-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,920,850

Underlying: Ordinary Shares · 300,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
May 05, 2025 Filed May 8, 2025 11:08 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 100,000 Not disclosed Strike: $3.94 Not disclosed
Disclosure

SEC source: 0001104659-25-045874 · tm2514463-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,820,853

Underlying: Ordinary Shares · 300,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
May 01, 2025 Filed May 2, 2025 14:28 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 75,266 Not disclosed Strike: $3.97 Not disclosed
Disclosure

SEC source: 0001104659-25-043878 · tm2513902-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,720,853

Underlying: Ordinary Shares · 225,798 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 30, 2025 Filed May 2, 2025 14:28 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 34,309 Not disclosed Strike: $3.66 Not disclosed
Disclosure

SEC source: 0001104659-25-043878 · tm2513902-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,645,587

Underlying: Ordinary Shares · 102,927 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 29, 2025 Filed Apr 30, 2025 11:13 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 54,768 Not disclosed Strike: $3.49 Not disclosed
Disclosure

SEC source: 0001104659-25-041787 · tm2513649-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,611,278

Underlying: Ordinary Shares · 164,304 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 28, 2025 Filed Apr 30, 2025 11:13 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 95,211 Not disclosed Strike: $3.43 Not disclosed
Disclosure

SEC source: 0001104659-25-041787 · tm2513649-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,556,510

Underlying: Ordinary Shares · 285,633 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 25, 2025 Filed Apr 28, 2025 10:50 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 59,568 Not disclosed Strike: $3.54 Not disclosed
Disclosure

SEC source: 0001104659-25-039744 · tm2513337-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,461,299

Underlying: Ordinary Shares · 178,704 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 24, 2025 Filed Apr 28, 2025 10:50 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 90,432 Not disclosed Strike: $3.42 Not disclosed
Disclosure

SEC source: 0001104659-25-039744 · tm2513337-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,401,731

Underlying: Ordinary Shares · 271,296 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 23, 2025 Filed Apr 24, 2025 11:16 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.18 Not disclosed
Disclosure

SEC source: 0001104659-25-038340 · tm2513097-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,311,299

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 22, 2025 Filed Apr 24, 2025 11:16 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.10 Not disclosed
Disclosure

SEC source: 0001104659-25-038340 · tm2513097-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,261,299

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 21, 2025 Filed Apr 22, 2025 14:35 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 100,000 Not disclosed Strike: $3.12 Not disclosed
Disclosure

SEC source: 0001104659-25-037215 · tm2512870-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,211,299

Underlying: Ordinary Shares · 300,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 17, 2025 Filed Apr 22, 2025 14:35 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.14 Not disclosed
Disclosure

SEC source: 0001104659-25-037215 · tm2512870-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,111,299

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 15, 2025 Filed Apr 15, 2025 18:17 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 27,918 Not disclosed Strike: $2.78 Not disclosed
Disclosure

SEC source: 0001104659-25-035039 · tm2512383-1_4seq1.xml · derivative · entry 5

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,061,299

Underlying: Ordinary Shares · 83,754 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 14, 2025 Filed Apr 15, 2025 18:17 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $2.65 Not disclosed
Disclosure

SEC source: 0001104659-25-035039 · tm2512383-1_4seq1.xml · derivative · entry 4

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,033,381

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 14, 2025 Filed Apr 15, 2025 18:17 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 40,409 Not disclosed Strike: $2.71 Not disclosed
Disclosure

SEC source: 0001104659-25-035039 · tm2512383-1_4seq1.xml · derivative · entry 3

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,983,381

Underlying: Ordinary Shares · 121,227 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 11, 2025 Filed Apr 15, 2025 18:17 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 56,480 Not disclosed Strike: $2.33 Not disclosed
Disclosure

SEC source: 0001104659-25-035039 · tm2512383-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,942,972

Underlying: Ordinary Shares · 169,440 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

Read SEC document
April 10, 2025 Filed Apr 15, 2025 18:17 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 25,193 Not disclosed Strike: $2.14 Not disclosed
Disclosure

SEC source: 0001104659-25-035039 · tm2512383-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,886,492

Underlying: Ordinary Shares · 75,579 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

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March 31, 2025 Filed Mar 31, 2025 14:47 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 100,000 Not disclosed Strike: $3.46 Not disclosed
Disclosure

SEC source: 0001104659-25-029715 · tm2510904-1_4seq1.xml · derivative · entry 3

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,761,299

Underlying: Ordinary Shares · 300,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities transactions listed were made by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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March 31, 2025 Filed Apr 1, 2025 11:50 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 100,000 Not disclosed Strike: $2.83 Not disclosed
Disclosure

SEC source: 0001104659-25-030241 · tm2511054-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,861,299

Underlying: Ordinary Shares · 300,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities transactions listed were made by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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March 28, 2025 Filed Mar 31, 2025 14:47 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.58 Not disclosed
Disclosure

SEC source: 0001104659-25-029715 · tm2510904-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,661,299

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities transactions listed were made by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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March 27, 2025 Filed Mar 31, 2025 14:47 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 50,000 Not disclosed Strike: $3.32 Not disclosed
Disclosure

SEC source: 0001104659-25-029715 · tm2510904-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,611,299

Underlying: Ordinary Shares · 150,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities transactions listed were made by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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March 05, 2025 Filed Mar 6, 2025 16:03 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 22,632 Not disclosed Strike: $4.50 Not disclosed
Disclosure

SEC source: 0001104659-25-021245 · tm258471-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,561,299

Underlying: Ordinary Shares · 67,896 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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February 18, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 60,000 Not disclosed Strike: $4.85 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 8

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,538,667

Underlying: Ordinary Shares · 180,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

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February 13, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 60,000 Not disclosed Strike: $4.17 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 7

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,478,667

Underlying: Ordinary Shares · 180,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

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February 13, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 92,774 Not disclosed Strike: $4.29 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 6

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,418,667

Underlying: Ordinary Shares · 278,322 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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January 23, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 12,226 Not disclosed Strike: $5.35 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 5

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,325,893

Underlying: Ordinary Shares · 36,678 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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January 21, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 20,000 Not disclosed Strike: $5.48 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 4

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,313,667

Underlying: Ordinary Shares · 60,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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January 21, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 25,000 Not disclosed Strike: $5.20 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 3

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,293,667

Underlying: Ordinary Shares · 75,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

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January 17, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 150,000 Not disclosed Strike: $5.35 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 2

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Cream Capital Limited

Disclosed balance after: 9,268,667

Underlying: Ordinary Shares · 450,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F2 · ownership.nature: The securities are held by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.

Read SEC document
January 08, 2025 Filed Feb 25, 2025 15:59 UTC Silence Therapeutics plc SLN · Entity 5028 PurchaseAmerican Depositary Shares · Derivative 30,000 Not disclosed Strike: $6.48 Not disclosed
Disclosure

SEC source: 0001104659-25-016802 · tm257556-1_4seq1.xml · derivative · entry 1

Griffiths Richard Ian · CIK 0001846370 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,118,667

Underlying: Ordinary Shares · 90,000 shares

Expires not disclosed

F1 · price: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.exercise_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

F1 · derivative.expiration_date: Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.