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person · Reporting owner

Goncalves Joana

Disclosed activity across 2 companies

Tapewire entity
23083
SEC CIK
0001756991

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Oruka Therapeutics, Inc.ORKA · Entity 3781Chief Medical OfficerSeptember 15, 2026September 15, 2026
Tvardi Therapeutics, Inc.CARA · Entity 7579CHIEF MEDICAL OFFICERApril 05, 2024April 09, 2024

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Oruka Therapeutics, Inc.

Report date September 15, 2026 · Filed September 15, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect31,771 Ending reported balance After 2026-09-15 transaction · row 7
7 source rows · reconciled sequence

Row 1 · 2026-09-15 · Exercise / conversion · Acquired 3,500 · Balance 36,218

Row 2 · 2026-09-15 · Exercise / conversion · Acquired 3,500 · Balance 39,718

Row 3 · 2026-09-15 · Sale · Disposed 2,384 · Balance 37,334

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $90.52 to $91.51, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4) and (5) to this Form 4.

Row 4 · 2026-09-15 · Sale · Disposed 3,150 · Balance 34,184

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $91.56 to $92.55, inclusive.

Row 5 · 2026-09-15 · Sale · Disposed 1,366 · Balance 32,818

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $92.62 to $93.54, inclusive.

Row 6 · 2026-09-15 · Sale · Disposed 100 · Balance 32,718

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F5: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $94.04 to $94.35, inclusive.

Row 7 · 2026-09-15 · Sale · Disposed 947 · Balance 31,771

F6: These sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

Employee Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.84 · Expires 2034-05-06Direct193,563 Reported balance After 2026-09-15 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-09-15 · Exercise / conversion · Disposed 3,500 · Balance 193,563

F7: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Employee Warrant (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $7.80 · Expires 2034-07-14Direct164,992 Reported balance After 2026-09-15 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2026-09-15 · Exercise / conversion · Disposed 3,500 · Balance 164,992

F8: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Filing footnotes · ownership attribution and instrument terms

F1: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $90.52 to $91.51, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4) and (5) to this Form 4.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $91.56 to $92.55, inclusive.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $92.62 to $93.54, inclusive.

F5: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $94.04 to $94.35, inclusive.

F6: These sales were effected pursuant to Oruka Therapeutics, Inc.'s automatic, non-discretionary, sell-to-cover procedure to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units.

F7: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

F8: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Tvardi Therapeutics, Inc.

Report date April 05, 2024 · Filed April 09, 2024

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect53,365 Reported balance After 2024-04-05 transaction · row 1
1 source row

Row 1 · 2024-04-05 · Sale · Disposed 2,753 · Balance 53,365

F1: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

Filing footnotes · ownership attribution and instrument terms

F1: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 16, 2026 Filed Mar 17, 2026 20:06 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 1,177 $41.94 $49,358.79
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,018

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.75 to $42.28, inclusive.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 2,902 $41.20 $119,568.78
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,195

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.72 to $41.70, inclusive.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 2,921 $40.11 $117,158.68
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,097

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.65 to $40.64, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3) and (4) to this Form 4.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 16, 2026 Filed Mar 17, 2026 20:06 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000030 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · derivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 189,492

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · derivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 218,063

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 936 $32.78 $30,686.01
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,018

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.69 to $32.93, inclusive.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 6,064 $32.30 $195,872.66
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,954

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.68 to $32.67, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 17, 2026 Filed Feb 17, 2026 22:24 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000020 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 GrantEmployee Stock Option (right to buy) · Derivative 130,000 $0.00 Strike: $34.39 $0.00
Disclosure

SEC source: 0000907654-26-000018 · form4.xml · derivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,000

Underlying: Common Stock · 130,000 shares

Expires 2036-01-22

F2 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2026.

Read SEC document
January 23, 2026 Filed Jan 23, 2026 22:40 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 GrantCommon Stock 32,500 $0.00 $0.00
Disclosure

SEC source: 0000907654-26-000018 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,018

F1 · shares: The grant vests as to 1/16 of the shares on each March 14, June 14, September 14 and December 14 (or if not a trading day, the immediately preceding trading day).

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · derivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 192,992

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · derivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 221,563

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 2,619 $32.24 $84,428.70
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,518

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.86 to $32.71, inclusive.

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 4,381 $31.56 $138,275.75
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,137

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.86 to $31.85, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4.

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 15, 2026 Filed Jan 16, 2026 22:26 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-26-000004 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Warrant (right to buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · derivative · entry 8

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 196,492

Underlying: Common Stock · 3,500 shares

Expires 2034-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The warrant vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 3,500 $0.00 Strike: $6.84 $0.00
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · derivative · entry 7

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 225,063

Underlying: Common Stock · 3,500 shares

Expires 2034-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests as to 1/4 of the underlying shares on April 18, 2025 and as to 1/48 of the underlying shares monthly from April 18, 2025.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 3,080 $31.58 $97,263.32
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 6

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,518

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.21 to $32.00, inclusive.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 1,492 $30.70 $45,806.04
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 5

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,598

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.20 to $31.18, inclusive.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 1,787 $29.62 $52,934.51
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 4

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,090

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.15 to $30.13, inclusive.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 SaleCommon Stock 641 $28.53 $18,289.14
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,877

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $28.14 to $29.12, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3), (4), (5) and (6) to this Form 4.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 19, 2025 Filed Dec 19, 2025 22:38 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 Exercise / conversionCommon Stock 3,500 $6.84 $23,940.00
Disclosure

SEC source: 0000907654-25-000023 · form4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,018

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 191 shares acquired under the Oruka stock purchase plan on December 8, 2024, 661 shares acquired under the Oruka stock purchase plan on June 8, 2025 and 666 shares acquired under the Oruka stock purchase plan on December 8, 2025.

Read SEC document
January 22, 2025 Filed Jan 24, 2025 21:43 UTC Oruka Therapeutics, Inc. ORKA · Entity 3781 GrantEmployee Stock Option (right to buy) · Derivative 162,500 $0.00 Strike: $12.50 $0.00
Disclosure

SEC source: 0001062993-25-001088 · form4.xml · derivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 162,500

Underlying: Common Stock · 162,500 shares

Expires 2035-01-21

F1 · derivative.exercise_date: The option vests as to 1/48 of the underlying shares monthly from January 1, 2025.

Read SEC document
April 05, 2024 Filed Apr 9, 2024 20:22 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,753 $0.83 $2,284.99
Disclosure

SEC source: 0001415889-24-010570 · form4-04092024_080455.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,365

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

Read SEC document
February 29, 2024 Filed Mar 4, 2024 21:13 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 3,293 $0.89 $2,930.77
Disclosure

SEC source: 0001415889-24-006265 · form4-03042024_090307.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,118

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

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February 01, 2024 Filed Feb 5, 2024 21:30 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantCommon Stock 13,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-24-002522 · form4-02052024_090202.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,181

F1 · shares: Represents the number of shares that vested under a performance-based restricted stock unit award (the "Award") granted on March 1, 2023 based on the Issuer's satisfaction of certain performance criteria of the Award. In light of the performance-based vesting conditions of the Award, such shares were not reportable under Section 16 until vesting was determined. On February 1, 2024, the Compensation Committee of the Issuer's Board of Directors certified a 50% level of achievement against the Award's performance goals.

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June 23, 2023 Filed Jun 27, 2023 20:07 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,723 $3.51 $9,557.73
Disclosure

SEC source: 0001209191-23-039882 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 53,681

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.45 to $3.51, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

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April 04, 2023 Filed Apr 6, 2023 21:13 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,481 $4.91 $12,181.71
Disclosure

SEC source: 0001209191-23-023606 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,404

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.82 to $4.91, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

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March 03, 2023 Filed Mar 7, 2023 21:43 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 6,221 $9.71 $60,405.91
Disclosure

SEC source: 0001209191-23-016788 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,885

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.60 to $9.71, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

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March 01, 2023 Filed Mar 3, 2023 21:37 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantStock Option (Right to Buy) · Derivative 81,000 $0.00 Strike: $10.06 $0.00
Disclosure

SEC source: 0001209191-23-015566 · doc4.xml · derivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,000

Underlying: Common Stock · 81,000 shares

Expires 2033-03-01

F1 · derivative.exercise_date: The shares shall vest and become exercisable in a series of 48 successive equal monthly installments beginning on April 1, 2023, in each case subject to the Reporting Person's continued service as of each such date.

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February 16, 2023 Filed Feb 17, 2023 21:27 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,265 $10.20 $23,103.00
Disclosure

SEC source: 0001209191-23-010627 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,106

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the Reporting Person.

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February 08, 2023 Filed Feb 12, 2024 22:13 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 7,770 $0.53 $4,118.10
Disclosure

SEC source: 0001415889-24-003400 · form4-02122024_100214.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,411

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person on March 12, 2020 in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units and does not represent a discretionary trade by the Reporting Person.

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January 17, 2023 Filed Jan 19, 2023 21:18 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,265 $10.81 $24,484.65
Disclosure

SEC source: 0001209191-23-004013 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,371

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the Reporting Person.

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December 29, 2022 Filed Jan 3, 2023 21:32 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,265 $10.18 $23,057.70
Disclosure

SEC source: 0001209191-23-000232 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,636

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the Reporting Person.

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December 21, 2022 Filed Dec 23, 2022 21:53 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,992 $11.27 $33,719.84
Disclosure

SEC source: 0001209191-22-062629 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,901

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units reported in the Form 4 filed with the Securities and Exchange Commission on December 21, 2021, and does not represent a discretionary trade by the Reporting Person.

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April 01, 2022 Filed Apr 5, 2022 21:50 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 1,642 $11.91 $19,556.22
Disclosure

SEC source: 0001209191-22-023248 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,893

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 on September 6, 2018 to satisfy the tax withholding obligations triggered by the vesting of restricted stock units reported in the Form 4 filed with the Securities and Exchange Commission on April 1, 2021, and does not represent a discretionary trade by the Reporting Person.

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February 25, 2022 Filed Mar 1, 2022 21:14 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantEmployee Stock Option (Right to Buy) · Derivative 80,000 $0.00 Strike: $10.46 $0.00
Disclosure

SEC source: 0001209191-22-013983 · doc4.xml · derivative · entry 3

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 80,000 shares

Expires 2032-02-25

F3 · derivative.exercise_date: The shares shall vest and become exercisable in a series of 48 successive equal monthly installments beginning on March 25, 2022, in each case subject to the Reporting Person's continued service as of each such date.

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February 25, 2022 Filed Mar 1, 2022 21:14 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 1,972 $10.29 $20,291.88
Disclosure

SEC source: 0001209191-22-013983 · doc4.xml · nonDerivative · entry 2

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,535

F2 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 on September 6, 2018 to satisfy the tax withholding obligations triggered by the vesting of RSUs reported in the Form 4 filed with the Securities and Exchange Commission on August 26, 2021, and does not represent a discretionary trade by the Reporting Person.

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February 25, 2022 Filed Mar 1, 2022 21:14 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantCommon Stock 20,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-22-013983 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,507

F1 · shares: Represents the number of shares underlying restricted stock units ("RSUs"). Each RSU represents the contingent right to receive one share of common stock of the Issuer. The RSUs vest in three equal annual installments on each of February 25, 2023, February 25, 2024 and February 25, 2025, in each case, subject to the Reporting Person's continued service (as that term is defined in the Issuer's 2014 Equity Incentive Plan) as of each such date.

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December 17, 2021 Filed Dec 21, 2021 22:29 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantCommon Stock 12,607 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-070808 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,507

F1 · shares: Represents the number of shares underlying restricted stock units ("RSUs") granted to the Reporting Person. Each RSU represents the contingent right to receive one share of common stock of the Issuer. The RSUs vest as to (i) 50% on December 15, 2022; and (ii) 50% on June 15, 2023, subject to the Reporting Person's continued service with the Issuer through each such vesting date.

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November 01, 2021 Filed Nov 3, 2021 20:55 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 1,000 $17.15 $17,150.00
Disclosure

SEC source: 0001209191-21-062727 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,900

F1 · kind: These shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2021.

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October 27, 2021 Filed Oct 28, 2021 22:34 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 1,000 $15.00 $15,000.00
Disclosure

SEC source: 0001209191-21-061953 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,900

F1 · kind: These shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2021.

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August 30, 2021 Filed Sep 1, 2021 22:06 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 2,110 $14.20 $29,962.00
Disclosure

SEC source: 0001209191-21-054301 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,900

F1 · kind: This sale was effected pursuant to a "sell to cover" arrangement adopted by the Reporting Person in accordance with Rule 10b5-1 on September 6, 2018 to satisfy the tax withholding obligations triggered by the vesting of RSUs reported in the Form 4 filed with the Securities and Exchange Commission on August 26, 2021, and does not represent a discretionary trade by the Reporting Person.

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August 24, 2021 Filed Aug 26, 2021 22:16 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 GrantCommon Stock 6,400 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-053536 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,010

F1 · shares: Represents the number of shares that vested under a performance-based restricted stock unit award (the "RSU") based on the Issuer's satisfaction of certain performance criteria of the award. In light of the performance-based vesting conditions of the award, such shares were not reportable under Section 16 until vesting was determined, which occurred on August 24, 2021. The vested shares represents the first of two possible vesting events of the total number of shares subject to the award. The remaining shares subject to the award will vest only upon the satisfaction of additional performance vesting criteria. Each RSU represents the contingent right to receive one share of common stock of the Issuer.

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April 21, 2021 Filed Apr 23, 2021 21:05 UTC Tvardi Therapeutics, Inc. CARA · Entity 7579 SaleCommon Stock 3,000 $27.63 $82,890.00
Disclosure

SEC source: 0001209191-21-028141 · doc4.xml · nonDerivative · entry 1

Goncalves Joana · CIK 0001756991 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,610

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 Trading Plan adopted by the Reporting Person on November 15, 2019 and amended on August 19, 2020.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.41 - $28.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.