Zalevsky Jonathan

SEC source: 0001193125-26-359588 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,570

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $71.78 to $72.49. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-26-316458 · ownership.xml · derivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,500

Underlying: Common Stock · 16,500 shares

Expires 2032-12-12

F1 · security: These stock options were granted on December 13, 2024 under the 2017 Amended and Restated Performance Incentive Plan and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a monthly pro-rata basis over a period of five years from the date of grant.

F2 · derivative.exercise_date: The Organization and Compensation Committee of the Board of Directors of the Issuer determined on July 23, 2026 that the performance-based vesting requirement for these stock options was satisfied and these stock options vested on July 24, 2026 (subject to remaining time-based vesting requirements).

SEC source: 0001193125-26-295112 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,756

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 13, 2026.

SEC source: 0001193125-26-274534 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,437

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 13, 2026.

F2 · price: This transaction was executed in multiple trades at prices ranging from $60.06 to $61.36. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-26-235030 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,975

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $64.88 to $68.43. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-26-061886 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,174

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $72.51 to $74.00. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-26-019843 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,354

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2025.

F2 · price: This transaction was executed in multiple trades at prices ranging from $35.17 to $36.23 The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-25-331189 · ownership.xml · derivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2033-12-21

F2 · derivative.exercise_date: Stock options vest over four years from the date of grant, (December 22, 2025) in substantially equal monthly installments based on continued service.

SEC source: 0001193125-25-331189 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,221

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs vest over four years from the date of grant (December 22, 2025) in substantially equal quarterly installments based on continued service.

SEC source: 0001193125-25-297855 · ownership.xml · nonDerivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,971

F3 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $58.26 to $59.56. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001193125-25-297855 · ownership.xml · derivative · entry 3

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,766

Underlying: Common Stock · 4,766 shares

Expires 2028-12-17

F5 · security: These stock options were granted on December 18, 2020 under the 2017 Plan and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a monthly pro-rata basis over a period of four years from the date of grant.

F6 · derivative.exercise_date: The Compensation Committee determined on November 20, 2025 that the performance-based vesting requirement for these stock options was satisfied and these stock options vested on November 21, 2025.

SEC source: 0001193125-25-297855 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,128

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs were granted on December 18, 2020 under the Issuer's Amended and Restated 2017 Performance Incentive Plan (the "2017 Plan") and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a quarterly pro-rata basis over a period of three years from the date of grant.

F2 · date: The Organization and Compensation Committee of the Board of Directors of the Issuer ("Compensation Committee") determined on November 20, 2025 that the performance-based vesting requirement for these RSUs was satisfied and these RSUs vested on November 21, 2025.

SEC source: 0000950170-25-113692 · ownership.xml · nonDerivative · entry 4

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,462

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F5 · price: This transaction was executed in multiple trades at prices ranging from $35.48 to $36.26. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-113692 · ownership.xml · nonDerivative · entry 3

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,769

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $34.09 to $34.95. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-113692 · ownership.xml · nonDerivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,958

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $33.08 to $34.07. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-113692 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,390

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $32.08 to $33.02 The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-113130 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,183

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $30.00 to $30.28 The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-110775 · ownership.xml · derivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,666

Underlying: Common Stock · 16,666 shares

Expires 2031-12-12

F4 · security: These stock options were granted on December 13, 2023 under the 2017 Plan and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a monthly pro-rata basis over a period of three years from the date of grant.

F5 · derivative.exercise_date: The Organization and Compensation Committee of the Board of Directors of the Issuer determined on July 17, 2025 that the performance-based vesting requirement for these stock options was satisfied and these stock options vested on August 19, 2025 (subject to remaining time-based vesting requirements).

SEC source: 0000950170-25-110775 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,668

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $26.19 to $27.15 The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

F3 · balance_after: On June 8, 2025, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the "Reverse Stock Split"). All amounts of securities listed herein have been adjusted to reflect the effect of the Reverse Stock Split.

SEC source: 0000950170-25-075979 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 305,892

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $0.66 to $0.69. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-25-025043 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 316,604

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.00 to $1.04. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-24-139242 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 326,904

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $.89 to $1.00. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-24-137545 · ownership.xml · derivative · entry 3

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 375,000

Underlying: Common Stock · 375,000 shares

Expires 2032-12-12

F5 · derivative.exercise_date: Stock options vest over four years from the date of grant, (December 13, 2024) in equal monthly installments based on continued service.

SEC source: 0000950170-24-137545 · ownership.xml · derivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 270,000

Underlying: Common Stock · 270,000 shares

Expires 2030-08-14

F3 · security: These stock options were granted on August 15, 2022 under the 2017 Plan and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a monthly pro-rata basis over a period of three years from the date of grant.

F4 · derivative.exercise_date: The Compensation Committee determined on November 18, 2024 that the performance-based vesting requirement for these stock options was satisfied and these stock options vested on December 13, 2024 (subject to remaining time-based vesting requirements).

SEC source: 0000950170-24-137545 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 378,019

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs were granted on August 15, 2022 under the Issuer's Amended and Restated 2017 Performance Incentive Plan (the "2017 Plan") and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a quarterly pro-rata basis over a period of three years from the date of grant.

F2 · date: The Organization and Compensation Committee of the Board of Directors of the Issuer ("Compensation Committee") determined on November 18, 2024 that the performance-based vesting requirement for these RSUs was satisfied and these RSUs vested on December 13, 2024 (subject to remaining time-based vesting requirements).

SEC source: 0000950170-24-129463 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 243,019

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.00 to $1.04. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-24-099354 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,804

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.24 to $1.32. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-24-062645 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 257,670

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.72 to $1.80. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0000950170-24-019045 · ownership.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 265,025

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $0.66 to $0.71. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon the request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-23-058861 · doc4.xml · derivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Stock · 250,000 shares

Expires 2031-12-12

F1 · derivative.exercise_date: This stock option vests over three years from the date of grant, (December 13, 2023) in equal monthly installments based on continued service.

SEC source: 0001209191-23-056184 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 274,039

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $0.47 to $0.52. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-23-046462 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 283,685

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $0.75 to $0.83. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-23-030448 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 293,388

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $0.71 to $0.75. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-23-010956 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 303,179

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $2.94 to $3.07. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-22-057968 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 313,663

F1 · shares: Represents the number of shares sold by the reporting person to cover required tax withholding obligations in connection with the vesting of the RSUs held by the reporting person and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $3.42 to $3.88. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-22-046909 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 327,123

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.56 to $4.70. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the Issuer.

SEC source: 0001209191-22-046489 · doc4.xml · nonDerivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 400,839

F2 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $4.67 to $4.88. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-22-046489 · doc4.xml · derivative · entry 3

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 270,000

Underlying: Common Stock · 270,000 shares

Expires 2030-08-14

F4 · security: Stock options were granted in connection with a retention program and are in lieu of the Issuer's usual end-of-year annual performance grants.

F5 · derivative.exercise_date: Stock options vest over three years from the date of grant in substantially equal monthly installments based on continued service.

SEC source: 0001209191-22-046489 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 411,399

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs were granted in connection with a retention program and are in lieu of the Issuer's usual end-of-year annual performance grants. These RSUs vest over three years from the date of grant in substantially equal quarterly installments based on continued service.

SEC source: 0001209191-22-029905 · doc4.xml · nonDerivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 276,399

F3 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $3.86 to $4.07. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001209191-22-029905 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,072

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs were granted on December 14, 2018 under the Issuer's Amended and Restated 2017 Performance Incentive Plan (the "2017 Plan") and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a quarterly pro-rata basis over a period of three (3) years from the date of grant.

F2 · date: The Organization and Compensation Committee of the Board of Directors of the Issuer determined that the performance-based vesting requirement for these RSUs was satisfied on May 13, 2022. Pursuant to the terms of the 2017 Plan, these RSUs vested on the next quarterly vesting date (May 15, 2022) following the date that the performance-based vesting requirement was satisfied.

SEC source: 0001209191-22-011442 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 274,122

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $10.77 to $11.20. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-21-070697 · doc4.xml · derivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,000

Underlying: Common Stock · 94,000 shares

Expires 2029-12-15

F2 · derivative.exercise_date: This stock option vests over four years from the date of grant in equal monthly installments based on continued service.

SEC source: 0001209191-21-070697 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 285,034

F1 · security: This stock award was acquired pursuant to a grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive, upon vesting of the unit, one share of the Issuer's common stock. These RSUs vest over three years from the date of grant in substantially equal quarterly installments based on continued service.

SEC source: 0001209191-21-065229 · doc4.xml · nonDerivative · entry 2

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 232,084

F3 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F4 · price: This transaction was executed in multiple trades at prices ranging from $12.84 to $13.52. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the Issuer, or a security holder of the Issuer.

SEC source: 0001209191-21-065229 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 252,953

F1 · security: Common stock was acquired pursuant to a grant of restricted stock units ("RSU"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of Common Stock of the Issuer. These RSUs were granted on December 12, 2019 under the Issuer's Amended and Restated 2017 Performance Incentive Plan (the "2017 Plan") and at the time of their grant were subject to both performance-based and time-based vesting requirements. The time-based vesting is on a quarterly pro-rata basis over a period of three (3) years from the date of grant.

F2 · date: The Organization and Compensation Committee of the Board of Directors of the Issuer determined that the performance-based vesting requirement for these RSUs was satisfied on September 15, 2021. Pursuant to the terms of the 2017 Plan, these RSUs vested on the next quarterly vesting date (November 15, 2021) following the date that the performance-based vesting requirement was satisfied.

SEC source: 0001209191-21-060513 · doc4.xml · derivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,550

Underlying: Common Stock · 71,550 shares

Expires 2027-12-11

F1 · security: These stock options were granted on December 12, 2019 under the Company's Amended and Restated 2017 Performance Incentive Plan (the "2017 Plan") and at the time of their grant were subject to both performance-based and time-based vesting requirements.

F2 · date: The Organization and Compensation Committee of the Board of Directors of the Company determined that the performance-based vesting requirement for these stock options was satisfied on September 15, 2021. Pursuant to the terms of the 2017 Plan, these stock options vested on the next monthly vesting date (October 12, 2021) following the date that the performance-based vesting requirement was satisfied.

F3 · derivative.exercise_date: These stock options vest on a monthly pro-rata basis over a period of four years from the grant date (December 12, 2019).

SEC source: 0001209191-21-052395 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 212,803

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $13.69 to $14.32. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F3 · balance_after: Since the date of the last ownership report of the reporting person, he transferred 14,600 shares of NKTR common stock to his ex-spouse pursuant to a domestic relations order. The reporting person no longer reports as beneficially owned any securities owned by his ex-spouse.

SEC source: 0001209191-21-034191 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 235,065

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $17.95 to $18.79. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

SEC source: 0001209191-21-012128 · doc4.xml · nonDerivative · entry 1

Zalevsky Jonathan · CIK 0001789857 · Chief R&D Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 266,176

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $22.04 to $22.67. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.