person · Reporting owner

MAETZOLD DEREK J

Disclosed activity across 1 company

Tapewire entity: 17918
SEC CIK: 0001239501

Reported relationships

Latest disclosed role at each company.

Company	Last reported as	Report date	Published
CASTLE BIOSCIENCES INCCSTL · Entity 359	Director · Pres. & Chief Exec. Officer	October 05, 2026	October 07, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

CASTLE BIOSCIENCES INC

Report date October 05, 2026 · Filed October 07, 2026

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	21,064	Ending reported balance After 2026-10-05 transaction · row 2 2 source rows · reconciled sequence Row 1 · 2026-10-05 · Exercise / conversion · Acquired 8,165 · Balance 29,644 F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026. Row 2 · 2026-10-05 · Sale · Disposed 8,580 · Balance 21,064 F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026. F2: This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
Common StockSEC Table I · non-derivative	IndirectBy The Maetzold Descendants 2020 Trust	8,038	Reported balance After 2026-10-05 transaction · row 3 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 3 · 2026-10-05 · Sale · Disposed 3,198 · Balance 8,038 F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026. F2: This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F3: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
Common StockSEC Table I · non-derivative	IndirectBy Derek Maetzold 2020 Irrevocable Trust	6,832	Reported balance After 2026-10-05 transaction · row 4 Account identity is unresolved; indirect or unspecified ownership is not merged. 1 source row Row 4 · 2026-10-05 · Sale · Disposed 2,718 · Balance 6,832 F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026. F2: This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F4: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
Stock option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.39 · Expires 2028-05-09	Direct	0	Reported balance After 2026-10-05 transaction · row 13 Instrument identity requires review; Table II rows are not merged. 1 source row Row 13 · 2026-10-05 · Exercise / conversion · Disposed 8,165 · Balance 0 F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026. F13: The shares subject to the option are fully vested.
Common StockSEC Table I · non-derivative	IndirectBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk	11,256	Reported balance Holding disclosure · report date 2026-10-05 · row 5 Holding and transaction disclosures are not merged. 1 source row Row 5 · Balance 11,256 F5: Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
Common StockSEC Table I · non-derivative	IndirectBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold	11,256	Reported balance Holding disclosure · report date 2026-10-05 · row 6 Holding and transaction disclosures are not merged. 1 source row Row 6 · Balance 11,256 F6: Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
Common StockSEC Table I · non-derivative	IndirectBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold	11,256	Reported balance Holding disclosure · report date 2026-10-05 · row 7 Holding and transaction disclosures are not merged. 1 source row Row 7 · Balance 11,256 F7: Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
Common StockSEC Table I · non-derivative	IndirectBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold	11,256	Reported balance Holding disclosure · report date 2026-10-05 · row 8 Holding and transaction disclosures are not merged. 1 source row Row 8 · Balance 11,256 F8: Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
Common StockSEC Table I · non-derivative	IndirectBy DJM Grantor Retained Annuity Trust No. 6	11,963	Reported balance Holding disclosure · report date 2026-10-05 · row 9 Holding and transaction disclosures are not merged. 1 source row Row 9 · Balance 11,963 F9: Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
Common StockSEC Table I · non-derivative	IndirectBy DJM Grantor Retained Annuity Trust No. 7	27,862	Reported balance Holding disclosure · report date 2026-10-05 · row 10 Holding and transaction disclosures are not merged. 1 source row Row 10 · Balance 27,862 F10: Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
Common StockSEC Table I · non-derivative	IndirectBy DJM Grantor Retained Annuity Trust No. 8	40,935	Reported balance Holding disclosure · report date 2026-10-05 · row 11 Holding and transaction disclosures are not merged. 1 source row Row 11 · Balance 40,935 F11: Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
Common StockSEC Table I · non-derivative	IndirectDJM Grantor Retained Annuity Trust No. 9	23,216	Reported balance Holding disclosure · report date 2026-10-05 · row 12 Holding and transaction disclosures are not merged. 1 source row Row 12 · Balance 23,216 F12: Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.

Filing footnotes · ownership attribution and instrument terms

F1: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026.

F2: This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F3: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.

F4: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.

F5: Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.

F6: Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

F7: Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

F8: Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.

F9: Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.

F10: Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.

F11: Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.

F12: Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.

F13: The shares subject to the option are fully vested.

Transaction history

JSON API

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction date	Company	Activity / security	Shares / units	Reported price	Reported value	Details
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	263	$73.69	$19,380.21	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 6 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 160,704 F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F6 · price: This transaction was executed in multiple trades at prices ranging from $73.070 to $73.930, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,403	$74.52	$104,547.35	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 5 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 136,461 F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F8 · price: This transaction was executed in multiple trades at prices ranging from $74.145 to $75.015, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F7 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	264	$73.69	$19,453.90	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 4 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 137,864 F5 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F6 · price: This transaction was executed in multiple trades at prices ranging from $73.070 to $73.930, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F7 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	511	$74.94	$38,291.79	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 3 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 316,018 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F4 · price: This transaction was executed in multiple trades at prices ranging from $74.880 to $75.015, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	8,531	$74.45	$635,124.42	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 2 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 316,529 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F3 · price: This transaction was executed in multiple trades at prices ranging from $73.870 to $74.860, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 15, 2021 Filed Sep 16, 2021 20:15 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	958	$73.30	$70,222.36	Disclosure SEC source: 0001447362-21-000223 · wf-form4_163182328808084.xml · nonDerivative · entry 1 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 325,060 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F2 · price: This transaction was executed in multiple trades at prices ranging from $72.860 to $73.830, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	186	$76.43	$14,215.05	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 8 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 148,365 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F7 · price: This transaction was executed in multiple trades at prices ranging from $76.300 to $76.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F8 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	227	$75.69	$17,181.86	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 7 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 148,551 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F6 · price: This transaction was executed in multiple trades at prices ranging from $75.105 to $76.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F8 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	473	$74.65	$35,308.03	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 6 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 148,778 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F5 · price: This transaction was executed in multiple trades at prices ranging from $74.100 to $75.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F8 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	781	$73.36	$57,293.38	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 5 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 149,251 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F2 · price: This transaction was executed in multiple trades at prices ranging from $73.050 to $73.940, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F8 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	186	$76.43	$14,215.05	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 4 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 160,967 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F7 · price: This transaction was executed in multiple trades at prices ranging from $76.300 to $76.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F4 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	227	$75.69	$17,181.86	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 3 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 161,153 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F6 · price: This transaction was executed in multiple trades at prices ranging from $75.105 to $76.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F4 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	472	$74.65	$35,233.38	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 2 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 161,380 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F5 · price: This transaction was executed in multiple trades at prices ranging from $74.100 to $75.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F4 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:16 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	781	$73.36	$57,293.38	Disclosure SEC source: 0001447362-21-000221 · wf-form4_163174413763011.xml · nonDerivative · entry 1 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 161,852 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F2 · price: This transaction was executed in multiple trades at prices ranging from $73.050 to $73.940, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F3 · balance_after: These transactions are a continuation of the transactions reported on a Form 4 filed contemporaneously herewith. F4 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	186	$76.43	$14,215.05	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 28 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 138,128 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F22 · price: This transaction was executed in multiple trades at prices ranging from $76.300 to $76.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F23 · balance_after: Transactions are continued on a Form 4 filed contemporaneously herewith. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	227	$75.69	$17,181.86	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 27 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 138,314 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F21 · price: This transaction was executed in multiple trades at prices ranging from $75.105 to $76.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	473	$74.65	$35,308.03	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 26 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 138,541 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F20 · price: This transaction was executed in multiple trades at prices ranging from $74.100 to $75.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	781	$73.36	$57,293.38	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 25 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 139,014 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F19 · price: This transaction was executed in multiple trades at prices ranging from $73.050 to $73.940, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,400	$76.45	$107,031.40	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 24 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 326,018 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F18 · price: This transaction was executed in multiple trades at prices ranging from $76.220 to $76.640, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,205	$75.56	$91,051.01	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 23 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 327,418 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F17 · price: This transaction was executed in multiple trades at prices ranging from $75.020 to $75.995, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	3,241	$74.63	$241,875.83	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 22 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 328,623 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F16 · price: This transaction was executed in multiple trades at prices ranging from $74.010 to $75.000, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 14, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	4,154	$73.32	$304,587.90	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 21 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 331,864 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F15 · price: This transaction was executed in multiple trades at prices ranging from $72.970 to $73.940, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	267	$74.69	$19,941.70	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 20 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 150,032 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F12 · price: This transaction was executed in multiple trades at prices ranging from $74.645 to $74.735, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F14 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	534	$73.99	$39,512.80	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 19 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 150,299 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F5 · price: This transaction was executed in multiple trades at prices ranging from $73.630 to $74.610, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F14 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	533	$72.94	$38,875.42	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 18 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 150,833 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F11 · price: This transaction was executed in multiple trades at prices ranging from $72.530 to $73.290, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F14 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	200	$71.49	$14,298.40	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 17 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 151,366 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F10 · price: This transaction was executed in multiple trades at prices ranging from $71.300 to $71.895, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F14 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	133	$70.47	$9,372.91	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 16 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 151,566 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F8 · price: This transaction was executed in multiple trades at prices ranging from $70.280 to $70.745, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F14 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	267	$74.69	$19,941.70	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 15 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 162,633 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F12 · price: This transaction was executed in multiple trades at prices ranging from $74.645 to $74.735, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	533	$73.99	$39,438.80	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 14 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 162,900 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F5 · price: This transaction was executed in multiple trades at prices ranging from $73.630 to $74.610, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	534	$72.94	$38,948.36	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 13 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 163,433 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F11 · price: This transaction was executed in multiple trades at prices ranging from $72.530 to $73.290, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	200	$71.49	$14,298.40	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 12 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 163,967 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F10 · price: This transaction was executed in multiple trades at prices ranging from $71.300 to $71.895, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	133	$70.47	$9,372.91	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 11 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 164,167 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F8 · price: This transaction was executed in multiple trades at prices ranging from $70.280 to $70.745, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	266	$74.69	$19,867.01	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 10 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 139,795 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F12 · price: This transaction was executed in multiple trades at prices ranging from $74.645 to $74.735, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	533	$73.99	$39,438.80	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 9 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 140,061 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F5 · price: This transaction was executed in multiple trades at prices ranging from $73.630 to $74.610, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	533	$72.94	$38,875.42	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 8 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 140,594 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F11 · price: This transaction was executed in multiple trades at prices ranging from $72.530 to $73.290, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	200	$71.49	$14,298.40	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 7 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 141,127 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F10 · price: This transaction was executed in multiple trades at prices ranging from $71.300 to $71.895, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	134	$70.47	$9,443.38	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 6 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By DJM Grantor Retained Annuity Trust No. 1 Disclosed balance after: 141,327 F7 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F8 · price: This transaction was executed in multiple trades at prices ranging from $70.280 to $70.745, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F9 · ownership.nature: Held by DJM Grantor Retained Annuity Trust No. 1 of which the Reporting Person is the trustee and beneficiary. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,700	$74.71	$127,003.60	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 5 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 336,018 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F6 · price: This transaction was executed in multiple trades at prices ranging from $74.630 to $74.840, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	2,788	$74.05	$206,448.61	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 4 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 337,718 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F5 · price: This transaction was executed in multiple trades at prices ranging from $73.630 to $74.610, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	3,112	$73.10	$227,484.09	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 3 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 340,506 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F4 · price: This transaction was executed in multiple trades at prices ranging from $72.610 to $73.600, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,400	$71.88	$100,629.20	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 2 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 343,618 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F3 · price: This transaction was executed in multiple trades at prices ranging from $71.610 to $72.530, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
September 13, 2021 Filed Sep 15, 2021 22:13 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	1,000	$70.64	$70,644.00	Disclosure SEC source: 0001447362-21-000219 · wf-form4_163174398958106.xml · nonDerivative · entry 1 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 345,018 F1 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 11, 2020. F2 · price: This transaction was executed in multiple trades at prices ranging from $70.140 to $71.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	200	$76.82	$15,363.80	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 16 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 151,699 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F11 · price: This transaction was executed in multiple trades at prices ranging from $76.720 to $76.910, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	833	$76.20	$63,473.77	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 15 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 151,899 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F10 · price: This transaction was executed in multiple trades at prices ranging from $75.690 to $76.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	500	$74.98	$37,491.00	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 14 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 152,732 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F9 · price: This transaction was executed in multiple trades at prices ranging from $74.650 to $75.640, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	133	$74.05	$9,849.18	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 13 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By Derek Maetzold 2020 Irrevocable Trust Disclosed balance after: 153,232 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F7 · price: This transaction was executed in multiple trades at prices ranging from $73.540 to $74.475, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F13 · ownership.nature: Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	201	$76.82	$15,440.62	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 12 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 164,300 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F11 · price: This transaction was executed in multiple trades at prices ranging from $76.720 to $76.910, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F12 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	833	$76.20	$63,473.77	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 11 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 164,501 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F10 · price: This transaction was executed in multiple trades at prices ranging from $75.690 to $76.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F12 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	500	$74.98	$37,491.00	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 10 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 165,334 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F9 · price: This transaction was executed in multiple trades at prices ranging from $74.650 to $75.640, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F12 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document
August 31, 2021 Filed Sep 2, 2021 21:27 UTC	CASTLE BIOSCIENCES INC CSTL · Entity 359	SaleCommon Stock	133	$74.05	$9,849.18	Disclosure SEC source: 0001447362-21-000211 · wf-form4_163061803252124.xml · nonDerivative · entry 9 MAETZOLD DEREK J · CIK 0001239501 · Director · Pres. & Chief Exec. Officer 10b5-1 filing: Not disclosed Ownership: Indirect · By The Maetzold Descendants 2020 Trust Disclosed balance after: 165,834 F6 · kind: These transactions were made pursuant to a Rule 10b5-1 plan adopted by DJM Grantor Retained Annuity Trust No. 1, The Maetzold Descendants 2020 Trust, and the Derek Maetzold 2020 Irrevocable Trust on June 15, 2021. F7 · price: This transaction was executed in multiple trades at prices ranging from $73.540 to $74.475, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. F12 · ownership.nature: Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.