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BRUM LYNNE H

Disclosed activity across 2 companies

Tapewire entity
17409
SEC CIK
0001197017

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875VP, Strategic CommunicationsMay 08, 2006May 09, 2006
YIELD10 BIOSCIENCE, INC.YTEN · Entity 88195VP Planning and CommunicationsAugust 15, 2024August 19, 2024

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

VERTEX PHARMACEUTICALS INC / MA

Report date May 08, 2006 · Filed May 09, 2006

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect46,199 Ending reported balance After 2006-05-08 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2006-05-08 · Exercise / conversion · Acquired 1,000 · Balance 47,199

Row 2 · 2006-05-08 · Sale · Disposed 1,000 · Balance 46,199

F1: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Row 3 · 2006-05-08 · Exercise / conversion · Acquired 1,250 · Balance 47,449

Row 4 · 2006-05-08 · Sale · Disposed 1,250 · Balance 46,199

F1: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $15.56 · Expires 2006-12-11Direct279,183 Reported balance After 2006-05-08 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2006-05-08 · Grant · Disposed 1,000 · Balance 279,183

F2: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $13.67 · Expires 2007-12-11Direct277,933 Reported balance After 2006-05-08 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2006-05-08 · Grant · Disposed 1,250 · Balance 277,933

F3: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/97.

Common StockSEC Table I · non-derivativeIndirect401(k)6,793 Reported balance Holding disclosure · report date 2006-05-08 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 6,793

Common StockSEC Table I · non-derivativeIndirectOwned by husband10 Reported balance Holding disclosure · report date 2006-05-08 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 10

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

F2: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

F3: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/97.

YIELD10 BIOSCIENCE, INC.

Report date August 15, 2024 · Filed August 19, 2024

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect5,867 Reported balance After 2024-08-15 transaction · row 1
1 source row

Row 1 · 2024-08-15 · Tax withholding · Disposed 731 · Balance 5,867

F1: Represents shares withheld in payment of withholding taxes upon partial vesting of RSUs granted 2/15/2024.

F2: Share numbers reflect the 1:24 reverse stock split effected on 5/2/2024.

Common StockSEC Table I · non-derivativeIndirectBy 401(k) Plan2,056 Reported balance Holding disclosure · report date 2024-08-15 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 2,056

F3: Shares acquired as Issuer matching contribution under the Yield10 Bioscience, Inc. 401(k) Plan.

Filing footnotes · ownership attribution and instrument terms

F1: Represents shares withheld in payment of withholding taxes upon partial vesting of RSUs granted 2/15/2024.

F2: Share numbers reflect the 1:24 reverse stock split effected on 5/2/2024.

F3: Shares acquired as Issuer matching contribution under the Yield10 Bioscience, Inc. 401(k) Plan.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 20, 2006 Filed Mar 21, 2006 17:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 400 $40.12 $16,048.00
Disclosure

SEC source: 0000875320-06-000029 · edgar.xml · nonDerivative · entry 3

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,187

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
March 20, 2006 Filed Mar 21, 2006 17:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $40.12 $40,120.00
Disclosure

SEC source: 0000875320-06-000029 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
March 20, 2006 Filed Mar 21, 2006 17:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000029 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 20, 2006 Filed Mar 28, 2006 21:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $35.87 $35,870.00
Disclosure

SEC source: 0000875320-06-000033 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,199

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
March 13, 2006 Filed Mar 14, 2006 17:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000026 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 288,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
March 13, 2006 Filed Mar 14, 2006 17:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $37.23 $37,230.00
Disclosure

SEC source: 0000875320-06-000026 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
March 13, 2006 Filed Mar 14, 2006 17:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000026 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 06, 2006 Filed Mar 7, 2006 18:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000025 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 289,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
March 06, 2006 Filed Mar 7, 2006 18:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $43.94 $43,940.00
Disclosure

SEC source: 0000875320-06-000025 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
March 06, 2006 Filed Mar 7, 2006 18:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000025 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 27, 2006 Filed Feb 28, 2006 19:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000023 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 290,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
February 27, 2006 Filed Feb 28, 2006 19:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $43.87 $43,870.00
Disclosure

SEC source: 0000875320-06-000023 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 27, 2006 Filed Feb 28, 2006 19:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000023 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 21, 2006 Filed Feb 22, 2006 18:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000021 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 291,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
February 21, 2006 Filed Feb 22, 2006 18:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $37.13 $37,130.00
Disclosure

SEC source: 0000875320-06-000021 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 21, 2006 Filed Feb 22, 2006 18:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000021 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 13, 2006 Filed Feb 14, 2006 17:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000018 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 292,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
February 13, 2006 Filed Feb 14, 2006 17:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $34.96 $34,960.00
Disclosure

SEC source: 0000875320-06-000018 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 13, 2006 Filed Feb 14, 2006 17:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000018 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 06, 2006 Filed Feb 7, 2006 20:02 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000017 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 293,433

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
February 06, 2006 Filed Feb 7, 2006 20:02 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $34.33 $34,330.00
Disclosure

SEC source: 0000875320-06-000017 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 06, 2006 Filed Feb 7, 2006 20:02 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000017 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,587

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 02, 2006 Filed Feb 6, 2006 21:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 14,066 $0.00 Strike: $35.64 $0.00
Disclosure

SEC source: 0000875320-06-000014 · edgar.xml · derivative · entry 4

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 294,433

Underlying: Common stock · 14,066 shares

Expires 2016-02-01

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 02/02/2006.

Read SEC document
February 02, 2006 Filed Feb 6, 2006 21:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 3,240 $0.01 $32.40
Disclosure

SEC source: 0000875320-06-000014 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,587

F1 · shares: Stock grant made under 1996 Stock and Option Plan, vesting on 2/2/2010, subject to acceleration upon achievement of certain performance-based milestones.

Read SEC document
January 31, 2006 Filed Feb 1, 2006 17:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000006 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 280,367

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
January 31, 2006 Filed Feb 1, 2006 17:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $35.29 $35,290.00
Disclosure

SEC source: 0000875320-06-000006 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,196

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
January 31, 2006 Filed Feb 1, 2006 17:54 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000006 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2006 Filed Jan 24, 2006 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000003 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 281,367

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1995 Stock and Option Plan, vesting quarterly over 5 years from 12/14/95.

Read SEC document
January 23, 2006 Filed Jan 24, 2006 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $33.63 $33,630.00
Disclosure

SEC source: 0000875320-06-000003 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,196

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
January 23, 2006 Filed Jan 24, 2006 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000003 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Strategic Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 17, 2006 Filed Jan 18, 2006 17:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 1,000 $0.00 Strike: $15.56 $0.00
Disclosure

SEC source: 0000875320-06-000002 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 282,367

Underlying: Common Stock · 1,000 shares

Expires 2006-12-11

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 5 years from 12/12/96.

Read SEC document
January 17, 2006 Filed Jan 18, 2006 17:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $33.62 $33,620.00
Disclosure

SEC source: 0000875320-06-000002 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,196

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
January 17, 2006 Filed Jan 18, 2006 17:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,000 $15.56 $15,560.00
Disclosure

SEC source: 0000875320-06-000002 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 06, 2005 Filed Dec 7, 2005 20:19 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 2,000 $0.00 Strike: $9.50 $0.00
Disclosure

SEC source: 0000875320-05-000071 · edgar.xml · derivative · entry 5

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 283,367

Underlying: Common Stock · 2,000 shares

Expires 2005-12-13

F2 · derivative.exercise_date: Right to buy under 1995 Stock and Option Plan, vesting quarterly over 5 years from 12/14/95.

Read SEC document
December 06, 2005 Filed Dec 7, 2005 20:19 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,000 $24.80 $49,600.00
Disclosure

SEC source: 0000875320-05-000071 · edgar.xml · nonDerivative · entry 2

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,196

F1 · kind: Transaction made pursuant to Ms. Brum's company approved trading plan established under Rule 10b5-1.

Read SEC document
December 06, 2005 Filed Dec 7, 2005 20:19 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,000 $9.50 $19,000.00
Disclosure

SEC source: 0000875320-05-000071 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 20, 2005 Filed Jul 22, 2005 19:04 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 10,230 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0000875320-05-000043 · edgar.xml · derivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 285,367

Underlying: Common stock · 10,230 shares

Expires 2015-07-19

F1 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 07/20/2005.

Read SEC document
February 03, 2005 Filed Feb 7, 2005 21:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 10,313 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0000875320-05-000007 · edgar.xml · derivative · entry 4

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 275,137

Underlying: Common stock · 10,313 shares

Expires 2015-02-02

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 02/03/2005.

Read SEC document
February 03, 2005 Filed Feb 7, 2005 21:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 2,375 $0.01 $23.75
Disclosure

SEC source: 0000875320-05-000007 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,196

F1 · shares: Stock grant made under 1996 Stock and Option Plan, vesting on 2/3/2009, subject to acceleration upon achievement of certain performance-based milestones.

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October 07, 2004 Filed Oct 12, 2004 18:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 7,500 $0.00 Strike: $11.27 $0.00
Disclosure

SEC source: 0000875320-04-000105 · edgar.xml · derivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 264,824

Underlying: Common Stock · 7,500 shares

Expires 2014-10-06

F1 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting quarterly over 4 years.

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May 06, 2004 Filed May 10, 2004 19:59 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 35,000 $0.01 $350.00
Disclosure

SEC source: 0000875320-04-000048 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,821

F1 · shares: Stock grant made under 1996 Stock and Option Plan, vesting 50% on May 6, 2009, subject to acceleration upon achievement of a performance-based milestone based on Company profitability, and 50% on May 6, 2007.

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March 17, 2004 Filed Mar 19, 2004 20:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 6,000 $0.00 Strike: $9.69 $0.00
Disclosure

SEC source: 0000875320-04-000018 · edgar.xml · derivative · entry 4

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 257,324

Underlying: Common stock · 6,000 shares

Expires 2014-03-16

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 03/17/2004.

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March 17, 2004 Filed Mar 19, 2004 20:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 800 $0.01 $8.00
Disclosure

SEC source: 0000875320-04-000018 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,821

F1 · shares: Stock grant made under 1996 Stock and Option Plan, vesting on 3/17/2008, subject to acceleration upon achievement of certain peformance-based milestones.

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December 11, 2003 Filed Dec 15, 2003 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 6,000 $0.00 Strike: $9.07 $0.00
Disclosure

SEC source: 0000875320-03-000056 · edgar.xml · derivative · entry 4

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 251,324

Underlying: Common stock · 6,000 shares

Expires 2013-12-10

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 12/11/2003.

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December 11, 2003 Filed Dec 15, 2003 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 800 $0.00 $0.00
Disclosure

SEC source: 0000875320-03-000056 · edgar.xml · nonDerivative · entry 1

BRUM LYNNE H · CIK 0001197017 · VP, Corp. Comm.&Financial Plan

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,021

F1 · shares: Stock grant made under 1996 Stock and Option Plan, vesting in 4 equal annual installments from 12/11/2003.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.