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Stamoulis Christiana

Disclosed activity across 5 companies

Tapewire entity
16615
SEC CIK
0001502917

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Cogent Biosciences, Inc.UMRX · Entity 3793President & C.F.O.March 28, 2018March 29, 2018
INCYTE CORPINCY · Entity 3182EVP & Chief Financial OfficerJuly 14, 2025July 16, 2025
Keenova Therapeutics plcNONE · Entity 28960President and CFOFebruary 25, 2026February 27, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875SVP, Corp Strategy & Bus DevlpJuly 30, 2013August 01, 2013

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Cogent Biosciences, Inc.

Report date March 28, 2018 · Filed March 29, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.18 · Expires 2025-01-28DirectNot disclosed Reported balance Holding disclosure · report date 2018-03-28 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: 25% of the shares vests on January 9, 2016, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $0.18 · Expires 2025-04-29DirectNot disclosed Reported balance Holding disclosure · report date 2018-03-28 · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · Balance Not disclosed

F2: 25% of the shares vest on April 30, 2016, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $9.77 · Expires 2027-10-26DirectNot disclosed Reported balance Holding disclosure · report date 2018-03-28 · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · Balance Not disclosed

F3: 25% of the shares vest on October 27, 2018, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $12.00 · Expires 2028-03-16DirectNot disclosed Reported balance Holding disclosure · report date 2018-03-28 · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · Balance Not disclosed

F4: 25% of the shares vest on March 28, 2019, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

Filing footnotes · ownership attribution and instrument terms

F1: 25% of the shares vests on January 9, 2016, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

F2: 25% of the shares vest on April 30, 2016, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

F3: 25% of the shares vest on October 27, 2018, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

F4: 25% of the shares vest on March 28, 2019, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Persons continuous service with the Issuer.

INCYTE CORP

Report date July 14, 2025 · Filed July 16, 2025

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect116,097 Reported balance After 2025-07-14 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2025-07-14 · Tax withholding · Disposed 1,407 · Balance 116,097

F1: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of RSUs or earned performance shares previously reported in Table I as common stock.

Common StockSEC Table I · non-derivativeDirect114,652 Reported balance After 2025-07-15 transaction · row 2 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 2 · 2025-07-15 · Tax withholding · Disposed 1,445 · Balance 114,652

F1: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of RSUs or earned performance shares previously reported in Table I as common stock.

Common StockSEC Table I · non-derivativeDirect125,759 Reported balance After 2025-07-15 transaction · row 3 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 3 · 2025-07-15 · Grant · Acquired 11,107 · Balance 125,759

F2: Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years. The RSUs may be settled only for shares of common stock on a one-for-one basis.

F3: Including the July 15, 2025 grant, this includes an aggregate of 64,006 shares of common stock issuable pursuant to previously reported RSUs and earned performance shares that have not vested.

Performance SharesSEC Table II · derivative / convertible security · Expires 2028-07-15Direct27,769 Reported balance After 2025-07-15 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2025-07-15 · Grant · Acquired 27,769 · Balance 27,769

F4: Each performance share represents the right to receive up to 200% of one share of common stock. Such shares may be earned based upon the issuer's relative total shareholder return ("TSR") over a three-year performance period beginning on January 1, 2025 as compared to the TSR of companies in a fixed peer group, as set forth in the Performance Share Award Agreement. The earned shares will vest on the third anniversary of the grant date subject to the Reporting Person's continued service with the issuer.

Employee Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $68.25 · Expires 2035-07-14Direct24,998 Reported balance After 2025-07-15 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2025-07-15 · Grant · Acquired 24,998 · Balance 24,998

F5: The July 15, 2025 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years.

Filing footnotes · ownership attribution and instrument terms

F1: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of RSUs or earned performance shares previously reported in Table I as common stock.

F2: Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years. The RSUs may be settled only for shares of common stock on a one-for-one basis.

F3: Including the July 15, 2025 grant, this includes an aggregate of 64,006 shares of common stock issuable pursuant to previously reported RSUs and earned performance shares that have not vested.

F4: Each performance share represents the right to receive up to 200% of one share of common stock. Such shares may be earned based upon the issuer's relative total shareholder return ("TSR") over a three-year performance period beginning on January 1, 2025 as compared to the TSR of companies in a fixed peer group, as set forth in the Performance Share Award Agreement. The earned shares will vest on the third anniversary of the grant date subject to the Reporting Person's continued service with the issuer.

F5: The July 15, 2025 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years.

Keenova Therapeutics plc

Report date February 25, 2026 · Filed February 27, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect174,181 Reported balance After 2026-02-25 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-02-25 · Grant · Acquired 101,262 · Balance 174,181

F1: Upon vesting, each restricted stock unit ("RSU") will be settled in ordinary shares of the Issuer at one share per RSU.

F2: The RSUs will vest ratably on each of the first three anniversaries of February 25, 2027.

Filing footnotes · ownership attribution and instrument terms

F1: Upon vesting, each restricted stock unit ("RSU") will be settled in ordinary shares of the Issuer at one share per RSU.

F2: The RSUs will vest ratably on each of the first three anniversaries of February 25, 2027.

VERTEX PHARMACEUTICALS INC / MA

Report date July 30, 2013 · Filed August 01, 2013

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $83.36 · Expires 2023-07-29Direct27,500 Reported balance After 2013-07-30 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2013-07-30 · Grant · Acquired 27,500 · Balance 27,500

F1: The option vests in 16 quarterly installments from 07/30/2013.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests in 16 quarterly installments from 07/30/2013.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

HOLOGIC INC

Report date April 07, 2026 · Filed April 09, 2026

Section 16 reporting ended · disclosed 2026-04-09. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2026-04-07 transaction · row 1
1 source row

Row 1 · 2026-04-07 · Disposition to issuer · Disposed 50,526 · Balance 0

F1: Pursuant to the Agreement and Plan of Merger, dated as of October 21, 2025 (the "Merger Agreement"), by and among Hologic, Inc. ("Hologic" or "Company"), Hopper Parent Inc., a Delaware corporation ("Parent"), and Hopper Merger Sub Inc., a Delaware corporation and wholly owned subsidiary of Parent ("Merger Sub"), Merger Sub merged with and into the Company (the "Merger"), with the Company surviving the Merger as a wholly owned subsidiary of Parent. At the effective time of the Merger (the "Effective Time"), each share of Hologic common stock, par value $0.01 ("Company Common Stock"), was converted into the right to receive (x) $76.00 per share in cash, without interest (the "Cash Consideration") and (y) one (1) contingent value right, which represents the right to receive up to $3.00 in cash, when and if payable (each, a "CVR") (the consideration contemplated by clauses (x) and (y), together, the "Merger Consideration").

F2: At the Effective Time, each time-vesting restricted stock unit award (a "Company RSU Award") held directly by the reporting person was converted into the right to receive the Merger Consideration in respect of each share of Company Common Stock underlying the Company RSU Award. As a result of the Merger, the reporting person no longer beneficially owns, directly or indirectly, any shares of Company Common Stock.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $41.92 · Expires 2027-03-08Direct0 Reported balance After 2026-04-07 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-04-07 · Disposition to issuer · Disposed 6,816 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $38.44 · Expires 2028-03-14Direct0 Reported balance After 2026-04-07 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-04-07 · Disposition to issuer · Disposed 7,551 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $46.81 · Expires 2029-03-07Direct0 Reported balance After 2026-04-07 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-04-07 · Disposition to issuer · Disposed 6,523 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $47.36 · Expires 2030-03-05Direct0 Reported balance After 2026-04-07 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-04-07 · Disposition to issuer · Disposed 7,322 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $71.03 · Expires 2031-03-11Direct0 Reported balance After 2026-04-07 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-04-07 · Disposition to issuer · Disposed 5,055 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $70.28 · Expires 2032-03-10Direct0 Reported balance After 2026-04-07 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-04-07 · Disposition to issuer · Disposed 5,293 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $78.49 · Expires 2033-03-09Direct0 Reported balance After 2026-04-07 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-04-07 · Disposition to issuer · Disposed 4,210 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $76.32 · Expires 2034-03-07Direct0 Reported balance After 2026-04-07 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2026-04-07 · Disposition to issuer · Disposed 4,536 · Balance 0

F3: For Footnote (3), see Remarks below.

Non-qualified Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $64.36 · Expires 2035-02-26Direct0 Reported balance After 2026-04-07 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2026-04-07 · Disposition to issuer · Disposed 5,535 · Balance 0

F3: For Footnote (3), see Remarks below.

Filing footnotes · ownership attribution and instrument terms

F1: Pursuant to the Agreement and Plan of Merger, dated as of October 21, 2025 (the "Merger Agreement"), by and among Hologic, Inc. ("Hologic" or "Company"), Hopper Parent Inc., a Delaware corporation ("Parent"), and Hopper Merger Sub Inc., a Delaware corporation and wholly owned subsidiary of Parent ("Merger Sub"), Merger Sub merged with and into the Company (the "Merger"), with the Company surviving the Merger as a wholly owned subsidiary of Parent. At the effective time of the Merger (the "Effective Time"), each share of Hologic common stock, par value $0.01 ("Company Common Stock"), was converted into the right to receive (x) $76.00 per share in cash, without interest (the "Cash Consideration") and (y) one (1) contingent value right, which represents the right to receive up to $3.00 in cash, when and if payable (each, a "CVR") (the consideration contemplated by clauses (x) and (y), together, the "Merger Consideration").

F2: At the Effective Time, each time-vesting restricted stock unit award (a "Company RSU Award") held directly by the reporting person was converted into the right to receive the Merger Consideration in respect of each share of Company Common Stock underlying the Company RSU Award. As a result of the Merger, the reporting person no longer beneficially owns, directly or indirectly, any shares of Company Common Stock.

F3: For Footnote (3), see Remarks below.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 08, 2017 Filed Mar 9, 2017 21:38 UTC HOLOGIC INC HOLX · Entity 12463 GrantCommon Stock 2,206 Not disclosed Not disclosed
Disclosure

SEC source: 0001127602-17-011066 · form4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,206

F1 · shares: Represents Restricted Stock Units (RSUs) which vest on the date of the 2018 Annual Meeting of Stockholders and are settled in shares of common stock.

F2 · price: RSUs convert into common stock on a one-for-one basis upon vesting.

Read SEC document
July 30, 2013 Filed Aug 1, 2013 20:15 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 27,500 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-13-038700 · doc4.xml · derivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,500

Underlying: Common Stock · 27,500 shares

Expires 2023-07-29

F1 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/30/2013.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 1,125 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0001209191-13-037018 · doc4.xml · derivative · entry 5

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,500

Underlying: Common Stock · 1,125 shares

Expires 2020-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/14/2010.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $87.33 $8,733.00
Disclosure

SEC source: 0001209191-13-037018 · doc4.xml · nonDerivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,712

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,025 $86.25 $88,406.25
Disclosure

SEC source: 0001209191-13-037018 · doc4.xml · nonDerivative · entry 2

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,812

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $86.25 (range $85.96 to $86.55).

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $33.82 $38,047.50
Disclosure

SEC source: 0001209191-13-037018 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,837

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 05, 2013 Filed Jul 9, 2013 20:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 4,687 $0.00 Strike: $34.57 $0.00
Disclosure

SEC source: 0001209191-13-035979 · doc4.xml · derivative · entry 5

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,688

Underlying: Common Stock · 4,687 shares

Expires 2019-10-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments beginning on 10/05/2009.

Read SEC document
July 05, 2013 Filed Jul 9, 2013 20:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,387 $81.42 $275,769.54
Disclosure

SEC source: 0001209191-13-035979 · doc4.xml · nonDerivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,712

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $81.42 (range $81.01 to $81.77).

Read SEC document
July 05, 2013 Filed Jul 9, 2013 20:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,300 $80.65 $104,845.00
Disclosure

SEC source: 0001209191-13-035979 · doc4.xml · nonDerivative · entry 2

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,099

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $80.65 (range $80.25 to $80.99).

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 05, 2013 Filed Jul 9, 2013 20:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,687 $34.57 $162,029.59
Disclosure

SEC source: 0001209191-13-035979 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,399

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 15, 2013 Filed May 17, 2013 20:15 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $80.50 $8,050.00
Disclosure

SEC source: 0001209191-13-027215 · doc4.xml · nonDerivative · entry 2

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,712

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2013 Filed May 17, 2013 20:15 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 502 $79.48 $39,898.96
Disclosure

SEC source: 0001209191-13-027215 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,812

F1 · kind: Transaction made pursuant to Ms. Stamoulis' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $79.48 (range $79.27 to $79.79).

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 30, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1 $0.00 Strike: $34.57 $0.00
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · derivative · entry 10

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,375

Underlying: Common Stock · 1 shares

Expires 2019-10-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 10/05/2009.

Read SEC document
April 30, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1 $77.88 $77.88
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 6

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,712

F1 · kind: Transaction made pursuant to Ms. Stamoulis's company approved trading plan under Rule 10b5-1.

Read SEC document
April 30, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1 $34.57 $34.57
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 5

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,713

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 12,375 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · derivative · entry 9

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,625

Underlying: Common Stock · 12,375 shares

Expires 2020-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 65,624 $0.00 Strike: $34.57 $0.00
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · derivative · entry 8

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,376

Underlying: Common Stock · 65,624 shares

Expires 2019-10-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 10/05/2009.

Read SEC document
April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 57,697 $79.69 $4,597,873.93
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 4

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,712

F1 · kind: Transaction made pursuant to Ms. Stamoulis's company approved trading plan under Rule 10b5-1.

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $79.69 (range $79.35 to $80.29).

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April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 25,302 $79.08 $2,000,882.16
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,409

F1 · kind: Transaction made pursuant to Ms. Stamoulis's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $79.08 (range $78.36 to $79.34).

F3 · price: Ms. Stamoulis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 12,375 $33.82 $418,522.50
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 2

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 123,711

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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April 29, 2013 Filed May 1, 2013 20:27 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 65,624 $34.57 $2,268,621.68
Disclosure

SEC source: 0001209191-13-023348 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,336

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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February 05, 2013 Filed Feb 7, 2013 22:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 45,750 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-13-007136 · doc4.xml · derivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,750

Underlying: Common Stock · 45,750 shares

Expires 2023-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/2013.

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February 05, 2013 Filed Feb 7, 2013 22:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0001209191-13-007136 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,712

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2017, subject to (i) acceleration of 50% of shares upon (a) receiving filing confirmation for an NDA for a combination regimen that includes both ivacaftor and a corrector compound or (b) receiving filing confirmation for an sNDA that would increase the number of patients with CF eligible for ivacaftor monotherapy, and (ii) acceleration of 50% of shares upon (a) the announcement of proof-of-concept data for a drug candidate other than an HCV, cystic fibrosis, influenza or JAK3 inhibition drug candidate or (b) reaching a specified net sales level over a twelve month period for our CF products.

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July 25, 2012 Filed Jul 26, 2012 20:52 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 30,500 $0.00 Strike: $48.74 $0.00
Disclosure

SEC source: 0001209191-12-039167 · doc4.xml · derivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common Stock · 30,500 shares

Expires 2022-07-24

F1 · derivative.exercise_date: The option vests in 16 quarterly installments beginning on 10/25/2012.

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February 02, 2012 Filed Feb 6, 2012 21:15 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 45,750 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-12-007783 · doc4.xml · derivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,750

Underlying: Common Stock · 45,750 shares

Expires 2022-02-01

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/02/2012.

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February 02, 2012 Filed Feb 6, 2012 21:15 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0001209191-12-007783 · doc4.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,708

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/2/2016, subject to (i) earlier acceleration of 50% of shares upon (A) reaching specified aggregate product and royalty sales levels or (B) completing enrollment of a pivotal trial in two distinct disease indications other than HCV and cystic fibrosis and (ii) earlier acceleration of 50% of shares upon receiving filing confirmation for an NDA for an all-oral regimen for the treatment of HCV infection.

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July 13, 2011 Filed Jul 14, 2011 19:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 30,500 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-11-039520 · doc4.xml · derivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,500

Underlying: Common Stock · 30,500 shares

Expires 2021-07-12

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/13/2011.

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February 03, 2011 Filed Feb 7, 2011 20:01 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 58,250 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000016 · edgar.xml · derivative · entry 3

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,250

Underlying: Common Stock · 58,250 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

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February 03, 2011 Filed Feb 7, 2011 20:01 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 10,166 $0.01 $101.66
Disclosure

SEC source: 0000875320-11-000016 · edgar.xml · nonDerivative · entry 1

Stamoulis Christiana · CIK 0001502917 · SVP, Corp Strategy & Bus Devlp

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,813

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.