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MUELLER PETER

Disclosed activity across 2 companies

Tapewire entity
16509
SEC CIK
0001256126

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
BioXcel Therapeutics, Inc.BTAI · Entity 8380DirectorJanuary 09, 2026January 12, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875EVP, Global R&D, CSOJune 16, 2014June 18, 2014

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

BioXcel Therapeutics, Inc.

Report date January 09, 2026 · Filed January 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.01 · Expires 2036-01-09Direct17,000 Reported balance After 2026-01-09 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-01-09 · Grant · Acquired 17,000 · Balance 17,000

F1: The option shall vest and become exercisable on the earlier of the first anniversary of the date of grant or the day immediately prior to the date of the next annual meeting of the Issuer's stockholders occurring after the date of grant, in either case, subject to the Reporting Person's continuing in service as a non-employee director through such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option shall vest and become exercisable on the earlier of the first anniversary of the date of grant or the day immediately prior to the date of the next annual meeting of the Issuer's stockholders occurring after the date of grant, in either case, subject to the Reporting Person's continuing in service as a non-employee director through such vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date June 16, 2014 · Filed June 18, 2014

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect151,017 Reported balance After 2014-06-16 transaction · row 1 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 1 · 2014-06-16 · Exercise / conversion · Acquired 7,500 · Balance 151,017

Common StockSEC Table I · non-derivativeDirect146,614 Reported balance After 2014-06-16 transaction · row 2 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 2 · 2014-06-16 · Sale · Disposed 4,403 · Balance 146,614

F1: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $67.72 (range $67.47 to $67.96).

F3: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Common StockSEC Table I · non-derivativeDirect145,114 Reported balance After 2014-06-16 transaction · row 3 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 3 · 2014-06-16 · Sale · Disposed 1,500 · Balance 145,114

F1: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $68.25 (range $68.04 to $68.86).

Common StockSEC Table I · non-derivativeDirect143,517 Reported balance After 2014-06-16 transaction · row 5 Sequence does not reconcile; account continuity is unresolved.
1 source row

Row 5 · 2014-06-16 · Sale · Disposed 1,000 · Balance 143,517

F1: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6: Open market sales reported on this line occurred at a weighted average price of $70.29 (range $70.00 to $70.99).

Common StockSEC Table I · non-derivativeDirect144,517 Reported balance After 2014-06-16 transaction · row 4
1 source row

Row 4 · 2014-06-16 · Sale · Disposed 597 · Balance 144,517

F1: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5: Open market sales reported on this line occurred at a weighted average price of $69.54 (range $69.15 to $69.95).

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $32.16 · Expires 2018-07-23Direct15,500 Reported balance After 2014-06-16 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2014-06-16 · Exercise / conversion · Disposed 7,500 · Balance 15,500

F8: Fully vested.

Common StockSEC Table I · non-derivativeIndirect401(k)4,770 Reported balance Holding disclosure · report date 2014-06-16 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 4,770

Common StockSEC Table I · non-derivativeIndirectRevocable Trust5,568 Reported balance Holding disclosure · report date 2014-06-16 · row 7 Holding and transaction disclosures are not merged.
1 source row

Row 7 · Balance 5,568

Common StockSEC Table I · non-derivativeIndirectCommon stock held in trust15,233 Reported balance Holding disclosure · report date 2014-06-16 · row 8 Holding and transaction disclosures are not merged.
1 source row

Row 8 · Balance 15,233

F7: Common stock held in grantor retained annuity trust.

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $67.72 (range $67.47 to $67.96).

F3: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $68.25 (range $68.04 to $68.86).

F5: Open market sales reported on this line occurred at a weighted average price of $69.54 (range $69.15 to $69.95).

F6: Open market sales reported on this line occurred at a weighted average price of $70.29 (range $70.00 to $70.99).

F7: Common stock held in grantor retained annuity trust.

F8: Fully vested.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
February 05, 2014 Filed Feb 7, 2014 21:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 51,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008356 · doc4.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,000

Underlying: Common Stock · 51,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 17,250 $0.01 $172.50
Disclosure

SEC source: 0001209191-14-008356 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 158,750

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

Read SEC document
January 15, 2014 Filed Jan 17, 2014 21:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 7,500 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-14-003731 · doc4.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,750

Underlying: Common Stock · 7,500 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
January 15, 2014 Filed Jan 17, 2014 21:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 7,500 $78.67 $590,025.00
Disclosure

SEC source: 0001209191-14-003731 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,500

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $78.67 (range $78.29 to $79.05).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 15, 2014 Filed Jan 17, 2014 21:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $28.84 $216,300.00
Disclosure

SEC source: 0001209191-14-003731 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 16, 2013 Filed Dec 17, 2013 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 7,500 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-13-057361 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,250

Underlying: Common Stock · 4,500 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
December 16, 2013 Filed Dec 17, 2013 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,100 $65.42 $137,382.00
Disclosure

SEC source: 0001209191-13-057361 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,500

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $65.42 (range $64.95 to $66.46).

Read SEC document
December 16, 2013 Filed Dec 17, 2013 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 5,400 $64.40 $347,760.00
Disclosure

SEC source: 0001209191-13-057361 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 143,600

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $64.40 (range $63.94 to $64.83).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
December 16, 2013 Filed Dec 17, 2013 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $28.84 $216,300.00
Disclosure

SEC source: 0001209191-13-057361 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 12, 2013 Filed Dec 12, 2013 22:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,900 $65.48 $189,892.00
Disclosure

SEC source: 0001209191-13-056698 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,500

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $65.48 (range $65.06 to $65.91).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 4,500 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · derivative · entry 9

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,750

Underlying: Common Stock · 4,500 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 3,000 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · derivative · entry 8

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,000 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,200 $63.12 $138,864.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · nonDerivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $63.12 (range $63.02 to $63.26).

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,200 $62.62 $263,004.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,600

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $62.62 (range $62.00 to $62.98).

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,100 $61.58 $67,738.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,800

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $61.58 (range $61.00 to $61.97).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,000 $18.93 $56,790.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 15, 2013 Filed Nov 19, 2013 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,500 $28.84 $129,780.00
Disclosure

SEC source: 0001209191-13-053081 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 15, 2013 Filed Oct 17, 2013 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-048645 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,000

Underlying: Common Stock · 7,500 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
October 15, 2013 Filed Oct 17, 2013 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 666 $73.85 $49,184.10
Disclosure

SEC source: 0001209191-13-048645 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $73.85 (range $73.67 to $74.16).

Read SEC document
October 15, 2013 Filed Oct 17, 2013 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,834 $73.19 $500,180.46
Disclosure

SEC source: 0001209191-13-048645 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,066

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $73.19 (range $72.66 to $73.65).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 15, 2013 Filed Oct 17, 2013 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $18.93 $141,975.00
Disclosure

SEC source: 0001209191-13-048645 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · derivative · entry 8

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,500

Underlying: Common Stock · 7,500 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 200 $79.08 $15,816.00
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · nonDerivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,320 $78.38 $103,461.60
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,600

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $78.38 (range $78.03 to $78.89).

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,895 $77.44 $224,188.80
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,920

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $77.44 (range $76.97 to $77.96).

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,085 $76.40 $235,694.00
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,815

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $76.40 (range $75.97 to $76.93).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
September 16, 2013 Filed Sep 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $18.93 $141,975.00
Disclosure

SEC source: 0001209191-13-044599 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 15, 2013 Filed Aug 19, 2013 20:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-041331 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 7,500 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
August 15, 2013 Filed Aug 19, 2013 20:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,000 $77.93 $233,790.00
Disclosure

SEC source: 0001209191-13-041331 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $77.93 (range $77.67 to $78.21).

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August 15, 2013 Filed Aug 19, 2013 20:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,500 $77.06 $346,770.00
Disclosure

SEC source: 0001209191-13-041331 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $77.06 (range $76.69 to $77.66).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 15, 2013 Filed Aug 19, 2013 20:16 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $18.93 $141,975.00
Disclosure

SEC source: 0001209191-13-041331 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 30, 2013 Filed Aug 1, 2013 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 34,000 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-13-038688 · doc4.xml · derivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,000

Underlying: Common Stock · 34,000 shares

Expires 2023-07-29

F1 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/30/2013.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-037015 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,500

Underlying: Common Stock · 7,500 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,535 $86.66 $219,683.10
Disclosure

SEC source: 0001209191-13-037015 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $86.66 (range $86.38 to $87.33).

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,965 $86.17 $427,834.05
Disclosure

SEC source: 0001209191-13-037015 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 146,935

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $86.17 (range $85.97 to $86.35).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 15, 2013 Filed Jul 17, 2013 20:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $18.93 $141,975.00
Disclosure

SEC source: 0001209191-13-037015 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · derivative · entry 11

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,000

Underlying: Common Stock · 7,500 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 9,800 $0.00 Strike: $16.32 $0.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · derivative · entry 10

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 9,800 shares

Expires 2013-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 105,000 $0.00 Strike: $33.00 $0.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · derivative · entry 9

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Stock · 105,000 shares

Expires 2019-10-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 39,365 $80.58 $3,172,031.70
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $80.58 (range $80.04 to $81.02).

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 68,985 $79.52 $5,485,687.20
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,765

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $79.52 (range $79.03 to $80.02).

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 13,950 $78.94 $1,101,213.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 252,750

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $78.94 (range $78.82 to $79.02).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $18.93 $141,975.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 266,700

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 9,800 $16.32 $159,936.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 259,200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 02, 2013 Filed Jul 3, 2013 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 105,000 $33.00 $3,465,000.00
Disclosure

SEC source: 0001209191-13-035485 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 249,400

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 16, 2013 Filed May 20, 2013 20:22 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GiftCommon Stock 10,352 $0.00 $0.00
Disclosure

SEC source: 0001209191-13-027552 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · Shares held by GRATS

Disclosed balance after: 0

F1 · ownership.nature: On May 16, 2013, grantor retained annuity trusts (GRATS) established by Dr. Mueller in 2010 that held 15,920 shares of common stock terminated in accordance with the terms of the GRATs. 10,352 shares were transferred to a trust established for the benefit of Dr. Mueller's adult child. The remaining 5,568 shares were distributed to revocable trusts established for the benefit of Dr. Mueller and his wife and are reported on this Form 4 as indirectly owned.

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February 05, 2013 Filed Feb 7, 2013 22:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 54,375 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-13-007128 · doc4.xml · derivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,375

Underlying: Common Stock · 54,375 shares

Expires 2023-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0001209191-13-007128 · doc4.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 144,400

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2017, subject to (i) acceleration of 50% of shares upon (a) receiving filing confirmation for an NDA for a combination regimen that includes both ivacaftor and a corrector compound or (b) receiving filing confirmation for an sNDA that would increase the number of patients with CF eligible for ivacaftor monotherapy, and (ii) acceleration of 50% of shares upon (a) the announcement of proof-of-concept data for a drug candidate other than an HCV, cystic fibrosis, influenza or JAK3 inhibition drug candidate or (b) reaching a specified net sales level over a twelve month period for our CF products.

Read SEC document
October 15, 2012 Filed Oct 16, 2012 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option Grant (right to buy) · Derivative 6,500 $0.00 Strike: $16.32 $0.00
Disclosure

SEC source: 0001209191-12-049586 · doc4.xml · derivative · entry 6

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,800

Underlying: Common Stock · 6,500 shares

Expires 2013-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Fully vested.

Read SEC document
October 15, 2012 Filed Oct 16, 2012 20:43 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,000 $53.14 $106,280.00
Disclosure

SEC source: 0001209191-12-049586 · doc4.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,316

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $53.14 (range $53.00 to $53.91).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.