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person · Reporting owner

SMITH IAN F

Disclosed activity across 7 companies

Tapewire entity
16070
SEC CIK
0001197032

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Acorda Therapeutics, Inc.ACOR · Entity 111987DirectorJune 27, 2018June 29, 2018
Foghorn Therapeutics Inc.FHTX · Entity 5820DirectorJune 24, 2026June 25, 2026
INFINITY PHARMACEUTICALS, INC.INFI · Entity 109802DirectorJune 12, 2018June 14, 2018
Odyssey Therapeutics, Inc.ODTX · Entity 4850DirectorMay 07, 2026May 12, 2026
Solid Biosciences Inc.SLDB · Entity 4915DirectorOctober 02, 2026October 06, 2026
Stoke Therapeutics, Inc.STOK · Entity 1723Director · Chief Executive OfficerFebruary 17, 2026February 19, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875EVP, COOJune 29, 2018July 03, 2018

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Acorda Therapeutics, Inc.

Report date June 27, 2018 · Filed June 29, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Non-Employee Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $28.15 · Expires 2028-06-27Direct15,000 Reported balance After 2018-06-27 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2018-06-27 · Grant · Acquired 15,000 · Balance 15,000

F1: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 27, 2018, with the first quarterly installment vesting on September 27, 2018.

Filing footnotes · ownership attribution and instrument terms

F1: The shares subject to this option vest in four equal quarterly installments over 12 months beginning on June 27, 2018, with the first quarterly installment vesting on September 27, 2018.

Foghorn Therapeutics Inc.

Report date June 24, 2026 · Filed June 25, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Options (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.08 · Expires 2036-06-23Direct28,000 Reported balance After 2026-06-24 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-24 · Grant · Acquired 28,000 · Balance 28,000

F1: The option vests in full on the first anniversary of the grant date, subject to the reporting person's continued service on the board of directors.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests in full on the first anniversary of the grant date, subject to the reporting person's continued service on the board of directors.

INFINITY PHARMACEUTICALS, INC.

Report date June 12, 2018 · Filed June 14, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect45,845 Reported balance After 2018-06-12 transaction · row 1
1 source row

Row 1 · 2018-06-12 · Grant · Acquired 22,857 · Balance 45,845

F1: Pursuant to the issuer's non-employee director compensation program, the reporting person has elected to receive this grant of shares in lieu of cash as payment of such person's $40,000 annual retainer for service as a director.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $1.75 · Expires 2028-06-12Direct20,000 Reported balance After 2018-06-12 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2018-06-12 · Grant · Acquired 20,000 · Balance 20,000

F2: The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as a director of the issuer.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $1.75 · Expires 2028-06-12Direct4,000 Reported balance After 2018-06-12 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2018-06-12 · Grant · Acquired 4,000 · Balance 4,000

F3: The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as Chair of the Audit Committee of the issuer's Board of Directors.

Filing footnotes · ownership attribution and instrument terms

F1: Pursuant to the issuer's non-employee director compensation program, the reporting person has elected to receive this grant of shares in lieu of cash as payment of such person's $40,000 annual retainer for service as a director.

F2: The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as a director of the issuer.

F3: The option vests over a period of one year in equal quarterly installments beginning at the end of the first quarter after the date of grant, provided that the holder continues to serve as Chair of the Audit Committee of the issuer's Board of Directors.

Odyssey Therapeutics, Inc.

Report date May 07, 2026 · Filed May 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $18.00 · Expires 2036-05-06Direct27,393 Reported balance After 2026-05-07 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-05-07 · Grant · Acquired 27,393 · Balance 27,393

F1: Option will vest in full on May 7, 2027, subject to the Reporting Person's continued service on each such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: Option will vest in full on May 7, 2027, subject to the Reporting Person's continued service on each such vesting date.

Solid Biosciences Inc.

Report date October 02, 2026 · Filed October 06, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect141,585 Reported balance After 2026-10-02 transaction · row 1
1 source row

Row 1 · 2026-10-02 · Exercise / conversion · Acquired 3,440 · Balance 141,585

F1: Restricted stock units convert to common stock on a one-for-one basis.

Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect3,440 Reported balance After 2026-10-02 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-10-02 · Exercise / conversion · Disposed 3,440 · Balance 3,440

F1: Restricted stock units convert to common stock on a one-for-one basis.

F2: The restricted stock units were granted on January 2, 2026 and vested in equal quarterly installments beginning three months from the date of grant, with the final installment vesting 12 months from the date of grant.

Filing footnotes · ownership attribution and instrument terms

F1: Restricted stock units convert to common stock on a one-for-one basis.

F2: The restricted stock units were granted on January 2, 2026 and vested in equal quarterly installments beginning three months from the date of grant, with the final installment vesting 12 months from the date of grant.

Stoke Therapeutics, Inc.

Report date February 17, 2026 · Filed February 19, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Employee Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $31.09 · Expires 2036-02-16Direct193,000 Reported balance After 2026-02-17 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-02-17 · Grant · Acquired 193,000 · Balance 193,000

F1: The option shall vest as to 1/48 of the total award on March 15, 2026, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Expires 2030-02-15Direct129,000 Reported balance After 2026-02-17 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-02-17 · Grant · Acquired 129,000 · Balance 129,000

F2: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the issuer's common stock upon settlement.

F3: The RSU award shall vest as to 1/4 of the total award annually with the first tranche vesting on February 15, 2027, subject to the reporting person's continued service to the issuer through each vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option shall vest as to 1/48 of the total award on March 15, 2026, with 1/48 vesting on each monthly anniversary thereafter, subject to the reporting person's continued service to the issuer through each vesting date.

F2: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the issuer's common stock upon settlement.

F3: The RSU award shall vest as to 1/4 of the total award annually with the first tranche vesting on February 15, 2027, subject to the reporting person's continued service to the issuer through each vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date June 29, 2018 · Filed July 03, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect46,699 Ending reported balance After 2018-06-29 transaction · row 3
3 source rows · reconciled sequence

Row 1 · 2018-06-29 · Exercise / conversion · Acquired 23,375 · Balance 70,074

Row 2 · 2018-06-29 · Sale · Disposed 4,741 · Balance 65,333

F1: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $165.22 (range $165.00 to $165.89).

F3: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Row 3 · 2018-06-29 · Sale · Disposed 18,634 · Balance 46,699

F1: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F3: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $166.57 (range $166.38 to $166.67).

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $131.89 · Expires 2025-07-20Direct10,625 Reported balance After 2018-06-29 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2018-06-29 · Exercise / conversion · Disposed 23,375 · Balance 10,625

F5: The option vests in 16 quarterly installments from 7/21/2015.

Common StockSEC Table I · non-derivativeIndirect401(k)5,306 Reported balance Holding disclosure · report date 2018-06-29 · row 4 Holding and transaction disclosures are not merged.
1 source row

Row 4 · Balance 5,306

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $165.22 (range $165.00 to $165.89).

F3: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $166.57 (range $166.38 to $166.67).

F5: The option vests in 16 quarterly installments from 7/21/2015.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 15, 2013 Filed May 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $80.50 $8,050.00
Disclosure

SEC source: 0001209191-13-027212 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,168

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2013 Filed May 17, 2013 20:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 509 $79.51 $40,470.59
Disclosure

SEC source: 0001209191-13-027212 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,268

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $79.51 (range $79.38 to $79.75).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 13,593 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 29

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,782

Underlying: Common Stock · 13,593 shares

Expires 2022-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/02/2012.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 15,858 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 28

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,392

Underlying: Common Stock · 15,858 shares

Expires 2021-07-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/13/2011.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 27,187 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 27

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,188

Underlying: Common Stock · 27,187 shares

Expires 2021-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 24,921 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 26

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,329

Underlying: Common Stock · 24,921 shares

Expires 2020-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy · Derivative 40,781 $0.00 Strike: $39.05 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 25

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,594

Underlying: Common Stock · 40,781 shares

Expires 2020-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/04/2010.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 300,000 $0.00 Strike: $33.00 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 24

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 300,000 shares

Expires 2019-10-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 33,983 $0.00 Strike: $33.28 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 23

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,267

Underlying: Common Stock · 33,983 shares

Expires 2019-07-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/16/2009.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 54,375 $0.00 Strike: $33.55 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 22

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 54,375 shares

Expires 2019-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 36,250 $0.00 Strike: $32.16 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 21

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 36,250 shares

Expires 2018-07-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 28,570 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 20

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 28,570 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 54,375 $0.00 Strike: $36.30 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 19

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 54,375 shares

Expires 2017-01-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 36,250 $0.00 Strike: $35.35 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 18

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 36,250 shares

Expires 2016-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 73,500 $0.00 Strike: $35.64 $0.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · derivative · entry 17

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 73,500 shares

Expires 2016-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 54,367 $85.00 $4,621,195.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 15

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,168

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 691,318 $81.50 $56,342,417.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 14

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,535

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 13,593 $37.86 $514,630.98
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 13

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 769,853

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 300,000 $33.00 $9,900,000.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 12

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 756,260

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 73,500 $35.64 $2,619,540.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 11

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 456,260

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 36,250 $32.16 $1,165,800.00
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 10

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 382,760

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 28,570 $28.84 $823,958.80
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 9

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 346,510

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 54,375 $36.30 $1,973,812.50
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 8

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 317,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 36,250 $35.35 $1,281,437.50
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,565

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 33,983 $33.28 $1,130,954.24
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,315

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 54,375 $33.55 $1,824,281.25
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 193,332

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 40,781 $39.05 $1,592,498.05
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138,957

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 24,921 $33.82 $842,828.22
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,176

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 27,187 $38.80 $1,054,855.60
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,255

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 15,858 $51.75 $820,651.50
Disclosure

SEC source: 0001209191-13-022280 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,068

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 54,375 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-13-007133 · doc4.xml · derivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,375

Underlying: Common Stock · 54,375 shares

Expires 2023-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0001209191-13-007133 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,210

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2017, subject to (i) acceleration of 50% of shares upon (a) receiving filing confirmation for an NDA for a combination regimen that includes both ivacaftor and a corrector compound or (b) receiving filing confirmation for an sNDA that would increase the number of patients with CF eligible for ivacaftor monotherapy, and (ii) acceleration of 50% of shares upon (a) the announcement of proof-of-concept data for a drug candidate other than an HCV, cystic fibrosis, influenza or JAK3 inhibition drug candidate or (b) reaching a specified net sales level over a twelve month period for our CF products.

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November 16, 2012 Filed Nov 20, 2012 21:19 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,042 $41.26 $249,292.92
Disclosure

SEC source: 0001209191-12-054065 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,126

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $41.26 (range $41.00 to $41.83).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 11, 2012 Filed Oct 15, 2012 20:44 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 6,363 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-12-049402 · doc4.xml · derivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,363 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
October 11, 2012 Filed Oct 15, 2012 20:44 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 7,680 $0.00 Strike: $28.84 $0.00
Disclosure

SEC source: 0001209191-12-049402 · doc4.xml · derivative · entry 5

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,570

Underlying: Common Stock · 7,680 shares

Expires 2017-07-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
October 11, 2012 Filed Oct 15, 2012 20:44 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 14,043 $60.00 $842,580.00
Disclosure

SEC source: 0001209191-12-049402 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,168

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

Read SEC document
October 11, 2012 Filed Oct 15, 2012 20:44 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 6,363 $18.93 $120,451.59
Disclosure

SEC source: 0001209191-12-049402 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,211

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 11, 2012 Filed Oct 15, 2012 20:44 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,680 $28.84 $221,491.20
Disclosure

SEC source: 0001209191-12-049402 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,848

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 7,875 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · derivative · entry 8

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,875 shares

Expires 2015-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 29,887 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · derivative · entry 7

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,363

Underlying: Common Stock · 29,887 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 6,187 $0.00 Strike: $10.41 $0.00
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · derivative · entry 6

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,187 shares

Expires 2015-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 44,787 $60.00 $2,687,220.00
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · nonDerivative · entry 4

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,168

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,875 $17.16 $135,135.00
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · nonDerivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,955

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 29,887 $18.93 $565,760.91
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · nonDerivative · entry 2

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,080

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 08, 2012 Filed Oct 9, 2012 20:25 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 6,187 $10.41 $64,406.67
Disclosure

SEC source: 0001209191-12-048728 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,193

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 25, 2012 Filed Jul 26, 2012 20:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 36,250 $0.00 Strike: $48.74 $0.00
Disclosure

SEC source: 0001209191-12-039166 · doc4.xml · derivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,250

Underlying: Common Stock · 36,250 shares

Expires 2022-07-24

F1 · derivative.exercise_date: The option vests in 16 quarterly installments beginning on 10/25/2012.

Read SEC document
February 08, 2012 Filed Feb 9, 2012 21:10 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 9,667 $36.80 $355,745.60
Disclosure

SEC source: 0001209191-12-008690 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,168

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $36.80 (range $36.48 to $37.20).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 02, 2012 Filed Feb 6, 2012 21:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 54,375 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-12-007782 · doc4.xml · derivative · entry 3

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,375

Underlying: Common Stock · 54,375 shares

Expires 2022-02-01

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/02/2012.

Read SEC document
February 02, 2012 Filed Feb 6, 2012 21:14 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0001209191-12-007782 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,835

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/2/2016, subject to (i) earlier acceleration of 50% of shares upon (A) reaching specified aggregate product and royalty sales levels or (B) completing enrollment of a pivotal trial in two distinct disease indications other than HCV and cystic fibrosis and (ii) earlier acceleration of 50% of shares upon receiving filing confirmation for an NDA for an all-oral regimen for the treatment of HCV infection.

Read SEC document
January 19, 2012 Filed Jan 23, 2012 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,042 $37.00 $223,554.00
Disclosure

SEC source: 0001209191-12-004855 · doc4.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,751

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $37.00 (range $36.85 to $37.11).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.