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person · Reporting owner

Silva Paul M

Disclosed activity across 3 companies

Tapewire entity
15694
SEC CIK
0001446372

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Nurix Therapeutics, Inc.NRIX · Entity 1156DirectorMay 15, 2026May 15, 2026
Rapport Therapeutics, Inc.RAPP · Entity 4394DirectorJune 10, 2026June 10, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875SVP & Chief Accounting OfficerFebruary 26, 2021March 02, 2021

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Nurix Therapeutics, Inc.

Report date May 15, 2026 · Filed May 15, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $15.86 · Expires 2036-05-14Direct31,250 Reported balance After 2026-05-15 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-05-15 · Grant · Acquired 31,250 · Balance 31,250

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Rapport Therapeutics, Inc.

Report date June 10, 2026 · Filed June 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.21 · Expires 2036-06-10Direct15,200 Reported balance After 2026-06-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 15,200 · Balance 15,200

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date February 26, 2021 · Filed March 02, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect9,884 Ending reported balance After 2021-03-01 transaction · row 5
5 source rows · reconciled sequence

Row 1 · 2021-02-26 · Tax withholding · Disposed 2,218 · Balance 12,666

Row 2 · 2021-03-01 · Sale · Disposed 1,026 · Balance 11,640

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Row 3 · 2021-03-01 · Sale · Disposed 610 · Balance 11,030

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

Row 4 · 2021-03-01 · Sale · Disposed 915 · Balance 10,115

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

Row 5 · 2021-03-01 · Sale · Disposed 231 · Balance 9,884

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Common StockSEC Table I · non-derivativeIndirect401(k)169 Reported balance Holding disclosure · report date 2021-02-26 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 169

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
February 23, 2015 Filed Feb 25, 2015 21:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 860 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-15-018504 · doc4.xml · derivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,593

Underlying: Common Stock · 860 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/30/2013.

Read SEC document
February 23, 2015 Filed Feb 25, 2015 21:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,150 $119.85 $257,677.50
Disclosure

SEC source: 0001209191-15-018504 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
February 23, 2015 Filed Feb 25, 2015 21:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,290 $77.31 $99,729.90
Disclosure

SEC source: 0001209191-15-018504 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,775

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 23, 2015 Filed Feb 25, 2015 21:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 860 $83.36 $71,689.60
Disclosure

SEC source: 0001209191-15-018504 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,485

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 18, 2015 Filed Feb 20, 2015 21:17 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,449 $113.16 $163,968.84
Disclosure

SEC source: 0001209191-15-016687 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $113.16 (range $113.03 to $113.30).

Read SEC document
February 18, 2015 Filed Feb 20, 2015 21:17 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,988 $112.71 $224,067.48
Disclosure

SEC source: 0001209191-15-016687 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,074

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $112.71 (range $112.02 to $113.00).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2015 Filed Feb 6, 2015 22:41 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,688 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-15-010443 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,500

Underlying: Common Stock · 1,688 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2015 Filed Feb 6, 2015 22:41 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 388 $110.76 $42,974.88
Disclosure

SEC source: 0001209191-15-010443 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,062

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $110.76 (range $110.50 to $111.03).

Read SEC document
February 05, 2015 Filed Feb 6, 2015 22:41 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 900 $109.74 $98,766.00
Disclosure

SEC source: 0001209191-15-010443 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,450

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $109.74 (range $109.45 to $110.13).

Read SEC document
February 05, 2015 Filed Feb 6, 2015 22:41 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 400 $108.81 $43,524.00
Disclosure

SEC source: 0001209191-15-010443 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,350

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $108.81 (range $108.27 to $109.10).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2015 Filed Feb 6, 2015 22:41 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,688 $45.11 $76,145.68
Disclosure

SEC source: 0001209191-15-010443 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,750

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 938 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · derivative · entry 12

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 938 shares

Expires 2021-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $111.32 $11,132.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 9

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,187

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $109.50 $10,950.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 8

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,287

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $108.16 $32,448.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 7

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,387

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $108.16 (range $108.03 to $108.40).

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 438 $107.04 $46,883.52
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,687

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $107.04 (range $106.77 to $107.45).

Read SEC document
February 03, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 938 $38.80 $36,394.40
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,125

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 03, 2015 Filed Feb 5, 2015 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option (right to buy) · Derivative 20,625 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-15-009903 · doc4.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,625

Underlying: Common Stock · 20,625 shares

Expires 2025-02-02

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2015.

Read SEC document
February 03, 2015 Filed Feb 5, 2015 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 6,875 $0.01 $68.75
Disclosure

SEC source: 0001209191-15-009903 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,062

F1 · shares: Performance-based restricted stock award that will vest as to (i) 50% of the shares on the earlier to occur of (a) the attainment of a specified level of net product sales in the United States of lumacaftor in combination with ivacaftor over four calendar quarters and (b) the announcement of the results of a clinical trial establishing proof-of-concept for a next generation CFTR corrector and (ii) 50% of the shares on the earlier to occur of (a) the attainment of a specified level of net product sales outside of the United States of lumacaftor in combination with ivacaftor over four calendar quarters and (b) the announcement of the results from a successful pivotal clinical trial for a non-cystic fibrosis drug candidate sufficient to support the filing of an NDA.

Read SEC document
February 02, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,125 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · derivative · entry 11

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,500

Underlying: Common Stock · 1,125 shares

Expires 2022-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2012.

Read SEC document
February 02, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 157 $110.76 $17,389.32
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,187

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $110.76 (range $110.74 to $110.80).

Read SEC document
February 02, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 668 $109.89 $73,406.52
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,344

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $109.89 (range $109.51 to $110.42).

Read SEC document
February 02, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $108.11 $32,433.00
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,012

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $108.11 (range $107.94 to $108.22).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 02, 2015 Filed Feb 4, 2015 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $37.86 $42,592.50
Disclosure

SEC source: 0001209191-15-009472 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,312

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 26, 2015 Filed Jan 28, 2015 22:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,125 $0.00 Strike: $48.74 $0.00
Disclosure

SEC source: 0001209191-15-007111 · doc4.xml · derivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,750

Underlying: Common Stock · 1,125 shares

Expires 2022-07-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/25/2012.

Read SEC document
January 26, 2015 Filed Jan 28, 2015 22:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 400 $126.27 $50,508.00
Disclosure

SEC source: 0001209191-15-007111 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,187

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $126.27 (range $126.00 to $126.56).

Read SEC document
January 26, 2015 Filed Jan 28, 2015 22:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 725 $125.26 $90,813.50
Disclosure

SEC source: 0001209191-15-007111 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,587

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $125.26 (range $124.99 to $125.83).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2015 Filed Jan 28, 2015 22:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $48.74 $54,832.50
Disclosure

SEC source: 0001209191-15-007111 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,312

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 13, 2015 Filed Jan 15, 2015 21:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,125 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-15-004435 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,250

Underlying: Common Stock · 1,125 shares

Expires 2021-07-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/13/2011.

Read SEC document
January 13, 2015 Filed Jan 15, 2015 21:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 400 $123.05 $49,220.00
Disclosure

SEC source: 0001209191-15-004435 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,187

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $123.05 (range $122.87 to $123.57).

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January 13, 2015 Filed Jan 15, 2015 21:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $122.28 $36,684.00
Disclosure

SEC source: 0001209191-15-004435 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,587

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $122.28 (range $121.83 to $122.62).

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January 13, 2015 Filed Jan 15, 2015 21:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 425 $120.61 $51,259.25
Disclosure

SEC source: 0001209191-15-004435 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,887

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $120.61 (range $120.36 to $120.93).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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January 13, 2015 Filed Jan 15, 2015 21:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $51.75 $58,218.75
Disclosure

SEC source: 0001209191-15-004435 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,312

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 12, 2014 Filed Dec 16, 2014 21:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,100 $120.48 $132,528.00
Disclosure

SEC source: 0001209191-14-075839 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,187

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $120.48 (range $120.28 to $120.84).

Read SEC document
December 12, 2014 Filed Dec 16, 2014 21:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,713 $119.82 $205,251.66
Disclosure

SEC source: 0001209191-14-075839 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,287

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $119.82 (range $119.20 to $120.19).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 28, 2014 Filed Dec 1, 2014 22:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 3,867 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-071981 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,758

Underlying: Common Stock · 3,867 shares

Expires 2024-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
November 28, 2014 Filed Dec 1, 2014 22:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 4,297 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-14-071981 · doc4.xml · derivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,453

Underlying: Common Stock · 4,297 shares

Expires 2023-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/30/2013.

Read SEC document
November 28, 2014 Filed Dec 1, 2014 22:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 8,164 $119.85 $978,455.40
Disclosure

SEC source: 0001209191-14-071981 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
November 28, 2014 Filed Dec 1, 2014 22:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,867 $77.31 $298,957.77
Disclosure

SEC source: 0001209191-14-071981 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,164

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 28, 2014 Filed Dec 1, 2014 22:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,297 $83.36 $358,197.92
Disclosure

SEC source: 0001209191-14-071981 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,297

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,687 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-14-067326 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,188

Underlying: Common Stock · 1,687 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2013.

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $114.29 $11,429.00
Disclosure

SEC source: 0001209191-14-067326 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 700 $112.93 $79,051.00
Disclosure

SEC source: 0001209191-14-067326 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,100

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $112.93 (range $112.60 to $113.49).

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 887 $112.07 $99,406.09
Disclosure

SEC source: 0001209191-14-067326 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,800

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $112.07 (range $111.54 to $112.32).

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,687 $45.11 $76,100.57
Disclosure

SEC source: 0001209191-14-067326 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,687

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2014 Filed Nov 5, 2014 22:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 1,125 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-14-066704 · doc4.xml · derivative · entry 7

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,625

Underlying: Common Stock · 1,125 shares

Expires 2022-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2012.

Read SEC document
November 03, 2014 Filed Nov 5, 2014 22:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 937 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0001209191-14-066704 · doc4.xml · derivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 938

Underlying: Common Stock · 937 shares

Expires 2021-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2011.

Read SEC document
November 03, 2014 Filed Nov 5, 2014 22:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $113.09 $11,309.00
Disclosure

SEC source: 0001209191-14-066704 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
November 03, 2014 Filed Nov 5, 2014 22:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,962 $111.97 $219,685.14
Disclosure

SEC source: 0001209191-14-066704 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,100

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $111.97 (range $111.66 to $112.29).

Read SEC document
November 03, 2014 Filed Nov 5, 2014 22:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $37.86 $42,592.50
Disclosure

SEC source: 0001209191-14-066704 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,062

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.