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ALTSHULER DAVID

Disclosed activity across 1 company

Tapewire entity
15000
SEC CIK
0001550395

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875EVP, Chief Scientific OfficerJanuary 22, 2026January 26, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

VERTEX PHARMACEUTICALS INC / MA

Report date January 22, 2026 · Filed January 26, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect34,477 Ending reported balance After 2026-01-22 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-01-22 · Grant · Acquired 7,866 · Balance 31,149

F1: Represents earned performance shares with respect to a performance stock unit award granted on 02/01/2023 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest on 02/13/2026.

Row 2 · 2026-01-22 · Grant · Acquired 3,328 · Balance 34,477

F2: Represents earned performance shares with respect to a performance stock unit award granted on 02/12/2025 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest in installments beginning on 02/24/2026.

Filing footnotes · ownership attribution and instrument terms

F1: Represents earned performance shares with respect to a performance stock unit award granted on 02/01/2023 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest on 02/13/2026.

F2: Represents earned performance shares with respect to a performance stock unit award granted on 02/12/2025 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest in installments beginning on 02/24/2026.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
February 19, 2019 Filed Feb 21, 2019 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 651 $187.40 $121,997.40
Disclosure

SEC source: 0001209191-19-011991 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,953

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $187.40 (range $187.12 to $187.96).

Read SEC document
February 19, 2019 Filed Feb 21, 2019 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,573 $186.81 $854,282.13
Disclosure

SEC source: 0001209191-19-011991 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,604

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $186.81 (range $186.09 to $187.08).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 11, 2019 Filed Feb 13, 2019 21:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $181.82 $18,182.00
Disclosure

SEC source: 0001209191-19-009652 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,177

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 11, 2019 Filed Feb 13, 2019 21:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,937 $181.03 $1,255,805.11
Disclosure

SEC source: 0001209191-19-009652 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,277

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $181.03 (range $180.76 to $181.52).

Read SEC document
February 11, 2019 Filed Feb 13, 2019 21:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 15,836 $180.33 $2,855,705.88
Disclosure

SEC source: 0001209191-19-009652 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,214

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $180.33 (range $179.77 to $180.74).

Read SEC document
February 11, 2019 Filed Feb 13, 2019 21:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10,083 $179.46 $1,809,495.18
Disclosure

SEC source: 0001209191-19-009652 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,050

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $179.46 (range $178.75 to $179.74).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option (Right to Buy) · Derivative 20,855 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-19-008546 · doc4.xml · derivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,855

Underlying: Common Stock · 20,855 shares

Expires 2029-02-05

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 8,166 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-008546 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,133

F3 · shares: Restricted stock unit award that vests in installments beginning on 2/24/2020.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 8,438 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-008546 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,967

F2 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/6/2018 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 2/6/2019. The earned performance shares will vest in installments beginning on 2/17/2019.

Read SEC document
February 06, 2019 Filed Feb 8, 2019 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 14,416 $0.00 $0.00
Disclosure

SEC source: 0001209191-19-008546 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,529

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 2/2/2016 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 2/6/2019 and the shares will vest on 2/10/2019.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · derivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,639

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2017.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · derivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,184

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2016.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,330 $189.19 $440,812.70
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,443

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,796 $189.19 $339,785.24
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 04, 2019 Filed Feb 6, 2019 21:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-19-007761 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,909

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 22, 2019 Filed Jan 24, 2019 21:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $131.89 $0.00
Disclosure

SEC source: 0001209191-19-005178 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,250

Underlying: Common Stock · 2,125 shares

Expires 2025-07-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/21/2015.

Read SEC document
January 22, 2019 Filed Jan 24, 2019 21:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,125 $193.48 $411,145.00
Disclosure

SEC source: 0001209191-19-005178 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
January 22, 2019 Filed Jan 24, 2019 21:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,125 $131.89 $280,266.25
Disclosure

SEC source: 0001209191-19-005178 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,238

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 18, 2019 Filed Jan 22, 2019 21:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,223 $0.00 Strike: $155.70 $0.00
Disclosure

SEC source: 0001209191-19-004722 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,898

Underlying: Common Stock · 1,223 shares

Expires 2028-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
January 18, 2019 Filed Jan 22, 2019 21:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,223 $194.62 $238,020.26
Disclosure

SEC source: 0001209191-19-004722 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
January 18, 2019 Filed Jan 22, 2019 21:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,223 $155.70 $190,421.10
Disclosure

SEC source: 0001209191-19-004722 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,336

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 15, 2018 Filed Nov 19, 2018 22:23 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $163.75 $16,375.00
Disclosure

SEC source: 0001209191-18-059246 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 07, 2018 Filed Nov 8, 2018 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $131.89 $0.00
Disclosure

SEC source: 0001209191-18-057744 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,375

Underlying: Common Stock · 2,125 shares

Expires 2025-07-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/21/2015.

Read SEC document
November 07, 2018 Filed Nov 8, 2018 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,125 $181.89 $386,516.25
Disclosure

SEC source: 0001209191-18-057744 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 07, 2018 Filed Nov 8, 2018 21:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,125 $131.89 $280,266.25
Disclosure

SEC source: 0001209191-18-057744 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,238

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 05, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · derivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,969

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2017.

Read SEC document
November 05, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,330 $172.08 $400,946.40
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 05, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,443

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 02, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · derivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,980

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/02/2016.

Read SEC document
November 02, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,796 $175.36 $314,946.56
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 02, 2018 Filed Nov 6, 2018 21:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-18-057370 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,909

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 01, 2018 Filed Oct 2, 2018 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,445 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-18-053152 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,121

Underlying: Common Stock · 2,445 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2018.

Read SEC document
October 01, 2018 Filed Oct 2, 2018 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,445 $194.62 $475,845.90
Disclosure

SEC source: 0001209191-18-053152 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
October 01, 2018 Filed Oct 2, 2018 20:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,445 $155.57 $380,368.65
Disclosure

SEC source: 0001209191-18-053152 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,558

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 28, 2018 Filed Aug 30, 2018 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,125 $0.00 Strike: $131.89 $0.00
Disclosure

SEC source: 0001209191-18-048923 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

Underlying: Common Stock · 2,125 shares

Expires 2025-07-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/21/2015.

Read SEC document
August 28, 2018 Filed Aug 30, 2018 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,125 $181.89 $386,516.25
Disclosure

SEC source: 0001209191-18-048923 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

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August 28, 2018 Filed Aug 30, 2018 20:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,125 $131.89 $280,266.25
Disclosure

SEC source: 0001209191-18-048923 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,238

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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August 03, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · derivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,299

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

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August 03, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,330 $174.20 $405,886.00
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 03, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,443

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · derivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,776

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

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August 02, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,796 $174.59 $313,563.64
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document
August 02, 2018 Filed Aug 6, 2018 21:42 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,796 $91.05 $163,525.80
Disclosure

SEC source: 0001209191-18-045583 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,909

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 16, 2018 Filed Jul 18, 2018 21:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 23,375 $0.00 Strike: $131.89 $0.00
Disclosure

SEC source: 0001209191-18-043125 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,625

Underlying: Common Stock · 23,375 shares

Expires 2025-07-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 7/21/2015.

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July 16, 2018 Filed Jul 18, 2018 21:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 23,375 $182.00 $4,254,250.00
Disclosure

SEC source: 0001209191-18-043125 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Dr. Altshuler's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $182.00 (range $181.89 to $182.16).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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July 16, 2018 Filed Jul 18, 2018 21:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 23,375 $131.89 $3,082,928.75
Disclosure

SEC source: 0001209191-18-043125 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,488

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 29, 2018 Filed Jul 3, 2018 20:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 11,649 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-18-041091 · doc4.xml · derivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,629

Underlying: Common Stock · 11,649 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/3/2017.

Read SEC document
June 29, 2018 Filed Jul 3, 2018 20:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,796 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-18-041091 · doc4.xml · derivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,572

Underlying: Common Stock · 1,796 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/2/2016.

Read SEC document
June 29, 2018 Filed Jul 3, 2018 20:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 5,000 $167.04 $835,200.00
Disclosure

SEC source: 0001209191-18-041091 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,113

F1 · kind: Transaction made pursuant to Mr. Altshuler's company-approved trading plan under Rule 10b5-1.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.