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ALTSHULER DAVID

Disclosed activity across 1 company

Tapewire entity
15000
SEC CIK
0001550395

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875EVP, Chief Scientific OfficerJanuary 22, 2026January 26, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

VERTEX PHARMACEUTICALS INC / MA

Report date January 22, 2026 · Filed January 26, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect34,477 Ending reported balance After 2026-01-22 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-01-22 · Grant · Acquired 7,866 · Balance 31,149

F1: Represents earned performance shares with respect to a performance stock unit award granted on 02/01/2023 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest on 02/13/2026.

Row 2 · 2026-01-22 · Grant · Acquired 3,328 · Balance 34,477

F2: Represents earned performance shares with respect to a performance stock unit award granted on 02/12/2025 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest in installments beginning on 02/24/2026.

Filing footnotes · ownership attribution and instrument terms

F1: Represents earned performance shares with respect to a performance stock unit award granted on 02/01/2023 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest on 02/13/2026.

F2: Represents earned performance shares with respect to a performance stock unit award granted on 02/12/2025 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 01/22/2026 and the shares will vest in installments beginning on 02/24/2026.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
February 13, 2023 Filed Feb 14, 2023 21:49 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 5,990 $298.26 $1,786,577.40
Disclosure

SEC source: 0001209191-23-009174 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,194

Read SEC document
February 10, 2023 Filed Feb 14, 2023 21:49 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 3,461 $294.33 $1,018,676.13
Disclosure

SEC source: 0001209191-23-009174 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,184

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,304 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · derivative · entry 8

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,304 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: Fully vested.

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 153 $309.06 $47,286.18
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,645

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $309.06 (range $308.76 to $309.42).

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 620 $306.70 $190,154.00
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,798

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $306.70 (range $306.32 to $307.25).

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 349 $305.08 $106,472.92
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,418

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $305.08 (range $304.72 to $305.43).

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $303.64 $30,364.00
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,767

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $303.64 (range $303.37 to $304.27).

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 70 $302.00 $21,140.00
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,867

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 12 $300.39 $3,604.68
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,937

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 06, 2023 Filed Feb 8, 2023 21:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,304 $187.53 $244,539.12
Disclosure

SEC source: 0001209191-23-007827 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,949

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 01, 2023 Filed Feb 3, 2023 21:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 7,866 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-006869 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,645

F3 · shares: Restricted stock unit award that vests in installments beginning on 02/10/2024.

Read SEC document
February 01, 2023 Filed Feb 3, 2023 21:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,314 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-006869 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,779

F2 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 02/01/2022 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/01/2023 and the shares will vest in installments beginning on 02/24/2023.

Read SEC document
February 01, 2023 Filed Feb 3, 2023 21:30 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,388 $0.00 $0.00
Disclosure

SEC source: 0001209191-23-006869 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,465

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 02/05/2020 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/01/2023 and the shares will vest on 02/13/2023.

Read SEC document
November 15, 2022 Filed Nov 17, 2022 21:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 34 $308.61 $10,492.74
Disclosure

SEC source: 0000899243-22-036184 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,303 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · derivative · entry 9

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,304

Underlying: Common Stock · 1,303 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 83 $306.57 $25,445.31
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 8

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $306.57 (range $306.45 to $307.22).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 140 $305.39 $42,754.60
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,160

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $305.39 (range $305.38 to $305.39).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 280 $304.58 $85,282.40
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,300

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $304.58 (range $304.14 to $304.91).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 261 $303.21 $79,137.81
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,580

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $303.21 (range $302.89 to $303.45).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 189 $301.99 $57,076.11
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,841

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $301.99 (range $301.84 to $302.20).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 210 $300.96 $63,201.60
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,030

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $300.96 (range $300.54 to $301.18).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 140 $299.72 $41,960.80
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,240

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $299.72 (range $299.46 to $299.97).

Read SEC document
November 07, 2022 Filed Nov 9, 2022 21:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,303 $187.53 $244,351.59
Disclosure

SEC source: 0000899243-22-035443 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,380

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,304 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · derivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,607

Underlying: Common Stock · 1,304 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 146 $295.14 $43,090.44
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $295.14 (range $294.74 to $295.53).

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 302 $293.99 $88,784.98
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,223

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $293.99 (range $293.58 to $294.26).

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 210 $293.02 $61,534.20
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,525

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $293.02 (range $292.41 to $293.36).

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 424 $291.53 $123,608.72
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,735

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $291.53 (range $291.06 to $291.91).

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 222 $290.32 $64,451.04
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,159

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $290.32 (range $290.05 to $290.64).

Read SEC document
August 08, 2022 Filed Aug 10, 2022 20:06 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,304 $187.53 $244,539.12
Disclosure

SEC source: 0000899243-22-028246 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,381

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 7,338 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · derivative · entry 8

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,338 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 10,427 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · derivative · entry 7

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,911

Underlying: Common Stock · 10,427 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,604 $289.48 $1,911,725.92
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F2 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $289.48 (range $289.11 to $290.06).

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 5,737 $288.67 $1,656,099.79
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,681

F2 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $288.67 (range $288.11 to $289.09).

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July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,561 $287.83 $1,312,792.63
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,418

F2 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $287.83 (range $287.11 to $288.10).

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 963 $286.72 $276,111.36
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,979

F2 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $286.72 (range $286.07 to $287.01).

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,338 $155.57 $1,141,572.66
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,942

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 19, 2022 Filed Jul 21, 2022 20:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 10,427 $187.53 $1,955,375.31
Disclosure

SEC source: 0000899243-22-026486 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,604

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 100 shares previously purchased under the issuer's Employee Stock Purchase Plan.

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February 25, 2022 Filed Feb 28, 2022 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 560 $232.68 $130,300.80
Disclosure

SEC source: 0000899243-22-008109 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,077

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $232.68 (range $232.43 to $232.87).

Read SEC document
February 25, 2022 Filed Feb 28, 2022 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,784 $231.64 $644,885.76
Disclosure

SEC source: 0000899243-22-008109 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,637

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $231.64 (range $231.08 to $232.07).

Read SEC document
February 25, 2022 Filed Feb 28, 2022 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,188 $230.62 $735,216.56
Disclosure

SEC source: 0000899243-22-008109 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,421

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $230.62 (range $230.07 to $231.05).

Read SEC document
February 25, 2022 Filed Feb 28, 2022 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,040 $229.41 $238,586.40
Disclosure

SEC source: 0000899243-22-008109 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,609

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $229.41 (range $228.91 to $229.81).

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 24, 2022 Filed Feb 28, 2022 22:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 6,038 $227.86 $1,375,818.68
Disclosure

SEC source: 0000899243-22-008109 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,649

Read SEC document
February 18, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,038 $233.27 $242,134.26
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,687

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $233.27 (range $232.91 to $233.50).

Read SEC document
February 18, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 600 $231.85 $139,110.00
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,725

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $231.85 (range $231.67 to $232.01).

Read SEC document
February 18, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 385 $231.01 $88,938.85
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,325

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $231.01 (range $230.66 to $231.43).

Read SEC document
February 18, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,303 $230.05 $299,755.15
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,710

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $230.05 (range $229.65 to $230.59).

Read SEC document
February 18, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 986 $229.22 $226,010.92
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,013

F1 · kind: Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $229.22 (range $228.65 to $229.60).

F3 · price: Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 17, 2022 Filed Feb 22, 2022 21:51 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 3,439 $232.51 $799,601.89
Disclosure

SEC source: 0000899243-22-007203 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,999

Read SEC document
February 14, 2022 Filed Feb 16, 2022 21:05 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,444 $232.02 $567,056.88
Disclosure

SEC source: 0001209191-22-010175 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,438

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $232.02 (range $231.82 to $232.60).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.