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Tatsis Ourania

Disclosed activity across 3 companies

Tapewire entity
14404
SEC CIK
0001789815

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Odyssey Therapeutics, Inc.ODTX · Entity 4850DirectorMay 07, 2026May 12, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875EVP, Chief Reg. & Quality Off.July 21, 2026July 23, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Odyssey Therapeutics, Inc.

Report date May 07, 2026 · Filed May 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $18.00 · Expires 2036-05-06Direct27,393 Reported balance After 2026-05-07 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-05-07 · Grant · Acquired 27,393 · Balance 27,393

F1: Option will vest in full on May 7, 2027, subject to the Reporting Person's continued service on each such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: Option will vest in full on May 7, 2027, subject to the Reporting Person's continued service on each such vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date July 21, 2026 · Filed July 23, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect53,572 Reported balance After 2026-07-21 transaction · row 1
1 source row

Row 1 · 2026-07-21 · Grant · Acquired 8,251 · Balance 53,572

F1: Restricted stock unit award that vests on 03/31/2030.

Filing footnotes · ownership attribution and instrument terms

F1: Restricted stock unit award that vests on 03/31/2030.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Verve Therapeutics, Inc.

Report date July 25, 2025 · Filed July 28, 2025

Section 16 reporting ended · disclosed 2025-07-28. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.02Direct0 Reported balance After 2025-07-25 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2025-07-25 · Disposition to issuer · Disposed 267,541 · Balance 0

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the

F2: (continued from footnote 1) applicable exercise price per share underlying such Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.73Direct0 Reported balance After 2025-07-25 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2025-07-25 · Disposition to issuer · Disposed 42,200 · Balance 0

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the

F2: (continued from footnote 1) applicable exercise price per share underlying such Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Filing footnotes · ownership attribution and instrument terms

F1: Pursuant to the terms of an Agreement and Plan of Merger, dated as of June 16, 2025, by and among the Issuer, Eli Lilly and Company ("Parent") and Parent's indirect wholly owned subsidiary, Ridgeway Acquisition Corporation, at the effective time of the Merger (the "Effective Time"), each outstanding stock option of Issuer having an exercise price less than $10.50 per share in cash, without interest and less any applicable tax withholding (the "Cash Consideration") (each such option, a "Cash-Out Stock Option") that is outstanding immediately prior to the Effective Time, whether or not vested, was automatically cancelled, by virtue of the Merger and without any action on the part of any holder of any Cash-Out Stock Option, and each holder of such Cash-Out Stock Option received (without interest) (i) an amount in cash (less any applicable tax withholdings) equal to the product of (a) the excess, if any, of the Cash Consideration over the

F2: (continued from footnote 1) applicable exercise price per share underlying such Cash-Out Stock Option multiplied by (b) the total number of shares of the Issuer's Common Stock subject to such Cash-Out Stock Option and (ii) one non-tradeable contingent value right for each share subject to such Cash-Out Stock Option (without regard to vesting).

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
February 24, 2021 Filed Feb 26, 2021 21:26 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 1,036 $217.57 $225,402.52
Disclosure

SEC source: 0001209191-21-014752 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,432

Read SEC document
February 17, 2021 Filed Feb 19, 2021 21:24 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 2,000 $211.75 $423,500.00
Disclosure

SEC source: 0001209191-21-012360 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,468

Read SEC document
February 10, 2021 Filed Feb 12, 2021 21:17 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 1,230 $214.16 $263,416.80
Disclosure

SEC source: 0001209191-21-010129 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,468

Read SEC document
February 03, 2021 Filed Feb 5, 2021 21:59 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 13,952 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-008154 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,698

F3 · shares: Restricted stock unit award that vests in installments beginning on 02/17/2022.

Read SEC document
February 03, 2021 Filed Feb 5, 2021 21:59 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 6,194 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-008154 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,746

F2 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 02/05/2020 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/03/2021 and the shares will vest in installments beginning on 02/10/2021.

Read SEC document
February 03, 2021 Filed Feb 5, 2021 21:59 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 2,814 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-008154 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,552

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 02/06/2018 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/03/2021 and the shares will vest on 02/17/2021.

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 9 $288.38 $2,595.42
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 7

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,738

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $288.38 (range $288.20 to $288.47).

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 33 $287.61 $9,491.13
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 6

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,747

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $287.61 (range $287.04 to $287.99).

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 20 $286.12 $5,722.40
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,780

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $286.12 (range $285.79 to $286.44).

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10 $284.30 $2,843.00
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,800

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 21 $281.23 $5,905.83
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,810

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $281.23 (range $280.73 to $281.62).

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 17 $279.93 $4,758.81
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,831

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $279.93 (range $279.68 to $280.53).

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 15, 2020 Filed May 19, 2020 20:33 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10 $276.35 $2,763.50
Disclosure

SEC source: 0001209191-20-030494 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,848

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 407 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · derivative · entry 10

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,854

Underlying: Common Stock · 407 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 559 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · derivative · entry 9

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,145

Underlying: Common Stock · 559 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 30 $275.30 $8,259.00
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 8

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,738

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 330 $274.13 $90,462.90
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 7

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,768

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $274.13 (range $273.75 to $274.73).

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 210 $273.15 $57,361.50
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 6

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,098

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $273.15 (range $272.73 to $273.50).

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 217 $272.09 $59,043.53
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,308

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $272.09 (range $271.73 to $272.54).

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 136 $270.19 $36,745.84
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,525

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $270.19 (range $269.71 to $270.61).

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 43 $268.80 $11,558.40
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,661

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $268.80 (range $268.65 to $269.12).

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 407 $155.57 $63,316.99
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,704

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 06, 2020 Filed May 8, 2020 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 559 $187.53 $104,829.27
Disclosure

SEC source: 0001209191-20-027906 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,297

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 240 $237.81 $57,074.40
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 7

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,738

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $237.81 (range $237.24 to $238.18).

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 160 $235.39 $37,662.40
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 6

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,978

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $235.39 (range $235.33 to $235.44).

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 240 $234.43 $56,263.20
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,138

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $234.43 (range $234.14 to $234.89).

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 80 $232.43 $18,594.40
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,378

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 160 $231.82 $37,091.20
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,458

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $231.82 (range $231.27 to $232.37).

Read SEC document
February 25, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 416 $229.57 $95,501.12
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,618

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $229.57 (range $229.15 to $229.91).

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 24, 2020 Filed Feb 26, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 1,036 $239.23 $247,842.28
Disclosure

SEC source: 0001209191-20-013039 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,034

Read SEC document
February 18, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 145 $245.75 $35,633.75
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 6

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,070

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $245.75 (range $245.54 to $245.85).

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February 18, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 286 $244.99 $70,067.14
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,215

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $244.99 (range $244.52 to $245.30).

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February 18, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 160 $243.78 $39,004.80
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,501

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $243.78 (range $243.42 to $244.23).

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February 18, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 528 $242.78 $128,187.84
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,661

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $242.78 (range $242.38 to $243.31).

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February 18, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 160 $241.82 $38,691.20
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,189

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $241.82 (range $241.33 to $242.18).

F3 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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February 17, 2020 Filed Feb 19, 2020 21:39 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Tax withholdingCommon Stock 597 $241.50 $144,175.50
Disclosure

SEC source: 0001209191-20-010560 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,349

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 408 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · derivative · entry 10

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,261

Underlying: Common Stock · 408 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

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February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 559 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · derivative · entry 9

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,704

Underlying: Common Stock · 559 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

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February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 66 $242.47 $16,003.02
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 8

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,946

F3 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 90 $240.70 $21,663.00
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 7

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,012

F3 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F5 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $240.70 (range $240.47 to $241.04).

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 240 $239.68 $57,523.20
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 6

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,102

F3 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F5 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $239.68 (range $239.25 to $240.13).

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 571 $238.77 $136,337.67
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,342

F3 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $238.77 (range $238.20 to $239.14).

F5 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 408 $155.57 $63,472.56
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,913

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 06, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 559 $187.53 $104,829.27
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,505

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 05, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 6,194 $0.00 $0.00
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,946

F2 · shares: Restricted stock unit award that vests in installments beginning on 02/10/2021.

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February 05, 2020 Filed Feb 7, 2020 21:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 3,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-20-007525 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,752

F1 · shares: Represents earned performance shares with respect to a performance stock unit award granted on 02/06/2019 that contained performance-vesting requirements. The issuer's management development and compensation committee certified as to the level of performance-goal attainment on 02/05/2020. The earned performance shares will vest in installments beginning on 2/24/2020.

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January 08, 2020 Filed Jan 10, 2020 21:22 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (Right to Buy) · Derivative 1,675 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-003055 · doc4.xml · derivative · entry 3

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,263

Underlying: Common Stock · 1,675 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 2/6/2019.

Read SEC document
January 08, 2020 Filed Jan 10, 2020 21:22 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,675 $227.53 $381,112.75
Disclosure

SEC source: 0001209191-20-003055 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,252

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document
January 08, 2020 Filed Jan 10, 2020 21:22 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,675 $187.53 $314,112.75
Disclosure

SEC source: 0001209191-20-003055 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,927

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 15, 2019 Filed Nov 19, 2019 21:17 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 5 $205.95 $1,029.75
Disclosure

SEC source: 0001209191-19-057152 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · SVP, CRO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,252

F1 · kind: Transaction made pursuant to Ms. Tatsis' company-approved trading plan under Rule 10b5-1.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.